Guadalupe Sabio

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 36

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III. Instituto de Salud Carlos III, Ministerio de Economía y Competitividad

Phosphophorylation Unit, Dundee, Scotland and University of Extremadura (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III. Instituto de Salud Carlos III, Ministerio de Economía y Competitividad

Spain

Assistant Professor

Centro Nacional de Biotecnología (CSIC)

Spain

researcher "Ramón y Cajal program"

Howard Hughes Medical Institute. University of Massachussets Medical School

United States

Research Associate

Spanish Ministry of Education. Dundee (Scotland) and University of Extremadura.

Spain

Fellowship

Spanish Ministry of Education . Universidad Of Extremadura

Spain

Graduate Student fellowship

Education History

Phosphophorylation Unit, Dundee, Scotland and University of Extremadura

Spain

PHD

Publications

Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesus Vazquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO reports (2024)
Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesus Vazquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO reports 25 (6) (2024)
Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesus Vazquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO reports 25 (6) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesus Vazquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO reports 25 (6) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Ana Belén Plata-Gómez, Lucía de Prado-Rivas, Alba Sanz, Nerea Deleyto-Seldas, Fernando Garcίa, Celia de la Calle Arregui, Camila Silva, Eduardo Caleiras, Osvaldo Graña-Castro, Elena Piñeiro-Yañez, Joseph Krebs, Luis Leiva-Vega, Javier Munoz, Ajay Jain, Guadalupe Sabio, Alejo Efeyan
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver. Nature communications 15 (1) (2024)
Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesus Vazquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis. EMBO reports 25 (6) (2024)
Cintia Folgueira, Leticia Herrera-Melle, Juan Antonio López, Victor Galvan-Alvarez, Marcos Martin-Rincon, María Isabel Cuartero, Alicia García-Culebras, Phillip A Dumesic, Elena Rodríguez, Luis Leiva, Marta León, Begoña Porteiro, Cristina Iglesias, Jorge L Torres, Lourdes Hernández-Cosido, Clara Bonacasa, Miguel Marcos, María Ángeles Moro, Jesus Vazquez, Jose A L Calbet, Bruce M Spiegelman, Alfonso Mora, Guadalupe Sabio
Remodeling p38 signaling in muscle controls locomotor activity via IL-15. Science advances 10 (33) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Ana Belén Plata-Gómez, Lucía de Prado-Rivas, Alba Sanz, Nerea Deleyto-Seldas, Fernando Garcίa, Celia de la Calle Arregui, Camila Silva, Eduardo Caleiras, Osvaldo Graña-Castro, Elena Piñeiro-Yañez, Joseph Krebs, Luis Leiva-Vega, Javier Munoz, Ajay Jain, Guadalupe Sabio, Alejo Efeyan
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver. Nature communications 15 (1) (2024)
Cintia Folgueira, Leticia Herrera-Melle, Juan Antonio López, Victor Galvan-Alvarez, Marcos Martin-Rincon, María Isabel Cuartero, Alicia García-Culebras, Phillip A Dumesic, Elena Rodríguez, Luis Leiva, Marta León, Begoña Porteiro, Cristina Iglesias, Jorge L Torres, Lourdes Hernández-Cosido, Clara Bonacasa, Miguel Marcos, María Ángeles Moro, Jesus Vazquez, Jose A L Calbet, Bruce M Spiegelman, Alfonso Mora, Guadalupe Sabio
Remodeling p38 signaling in muscle controls locomotor activity via IL-15. Science advances 10 (33) (2024)
Ana Belén Plata-Gómez, Lucía de Prado-Rivas, Alba Sanz, Nerea Deleyto-Seldas, Fernando Garcίa, Celia de la Calle Arregui, Camila Silva, Eduardo Caleiras, Osvaldo Graña-Castro, Elena Piñeiro-Yañez, Joseph Krebs, Luis Leiva-Vega, Javier Munoz, Ajay Jain, Guadalupe Sabio, Alejo Efeyan
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver. Nature communications 15 (1) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
María Ángeles García-López, Alfonso Mora, Patricia Corrales, Tirso Pons, Ainhoa Sánchez de Diego, Amaia Talavera Gutiérrez, Karel H M van Wely, Gema Medina-Gómez, Guadalupe Sabio, Carlos Martinez-A, Thierry Fischer
DIDO is necessary for the adipogenesis that promotes diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 121 (3) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Rafael Romero-Becerra, Francisco M Cruz, Alfonso Mora, Juan Antonio Lopez, Daniela Ponce-Balbuena, Andrew Allan, Roberto Ramos-Mondragón, Barbara Gonzalez-Teran, Marta León, Maria Elena Rodríguez, Luis Leiva-Vega, Guadalupe Guerrero-Serna, Eric N Jimenez-Vazquez, David Filgueiras-Rama, Jesus Vazquez, Jose Jalife, Guadalupe Sabio
p38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmia. Nature cardiovascular research 2 (12) (2023)
Rafael Romero-Becerra, Francisco M Cruz, Alfonso Mora, Juan Antonio Lopez, Daniela Ponce-Balbuena, Andrew Allan, Roberto Ramos-Mondragón, Barbara Gonzalez-Teran, Marta León, Maria Elena Rodríguez, Luis Leiva-Vega, Guadalupe Guerrero-Serna, Eric N Jimenez-Vazquez, David Filgueiras-Rama, Jesus Vazquez, Jose Jalife, Guadalupe Sabio
p38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmia. Nature cardiovascular research 2 (12) (2023)
María Fernández-Regueras, Cristina Carbonell, Daniel Salete-Granado, Juan Luis García Hernández, Marcos Gragera, María-Ángeles Pérez-Nieto, Francisco Javier Morán-Plata, Andrea Mayado, Jorge-Luis Torres, Luis-Antonio Corchete, Ricardo Usategui-Martín, Elena Bueno-Martínez, Maura Rojas-Pirela, Guadalupe Sabio, Rogelio González Sarmiento, Alberto Orfao, Francisco-Javier Laso, Julia Almeida, Miguel Marcos
Predominantly Pro-Inflammatory Phenotype with Mixed M1/M2 Polarization of Peripheral Blood Classical Monocytes and Monocyte-Derived Macrophages among Patients with Excessive Ethanol Intake. Antioxidants (Basel, Switzerland) 12 (9) (2023)
Veronica Pena-Leon, Cintia Folgueira, Silvia Barja-Fernández, Raquel Pérez-Lois, Natália Da Silva Lima, Marion Martin, Violeta Heras, Sara Martinez-Martinez, Paola Valero, Cristina Iglesias, Mannon Duquenne, Omar Al-Massadi, Daniel Beiroa, Yara Souto, Miguel Fidalgo, Sowmyalakshmi Rasika, Diana Guallar, Juan Cunarro, Cecilia Castelao, Ana Senra, Patricia González-Saenz, Rocío Vázquez-Cobela, Rosaura Leis, Guadalupe Sabio, Helge Müller-Fielitz, Markus Schwaninger, Miguel López, Sulay Tovar, Felipe F Casanueva, Emmanuel Valjent, Carlos Diéguez, Vincent Prevot, Ruben Nogueiras, Luisa M Seoane
Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21. Nature metabolism 4 (7) (2022)
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva-Vega, Aránzazu Pintor-Chocano, Daniel Horrillo, Lourdes Hernández-Cosido, Jorge L Torres, Eva Novoa, Rubén Nogueiras, Gema Medina-Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio
Myeloid p38 activation maintains macrophage-liver crosstalk and BAT thermogenesis through IL-12-FGF21 axis. Hepatology (Baltimore, Md.) (2022)
Diego Rodriguez-Muñoz, Ángela Sánchez, Susana Pérez-Benavente, Constanza Contreras-Jurado, Ana Montero-Pedrazuela, Marta Toledo-Castillo, María Gutiérrez-Hernández, Raquel Rodrigues-Díez, Cintia Folgueira, Ana M Briones, Guadalupe Sabio, Ignacio Monedero-Cobeta, Irene Chaves-Coira, David Castejón, Encarnación Fernández-Valle, Javier Regadera, José M Bautista, Ana Aranda, Susana Alemany
Hypothyroidism confers tolerance to cerebral malaria. Science advances 8 (14) (2022)
Rafael Romero-Becerra, Alfonso Mora, Elisa Manieri, Ivana Nikolic, Ayelén Melina Santamans, Valle Montalvo-Romeral, Francisco Miguel Cruz, Elena Rodríguez, Marta León, Luis Leiva-Vega, Laura Sanz, Víctor Bondía, David Filgueiras-Rama, Luis Jesús Jiménez-Borreguero, Jose Jalife, Barbara Gonzalez-Teran, Guadalupe Sabio
MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation. eLife 11 (2022)
Celia de la Calle Arregui, Ana Belén Plata-Gómez, Nerea Deleyto-Seldas, Fernando Garcίa, Ana Ortega-Molina, Julio Abril-Garrido, Elena Rodriguez, Ivan Nemazanyy, Laura Tribouillard, Alba de Martino, Eduardo Caleiras, Ramón Campos-Olivas, Francisca Mulero, Mathieu Laplante, Javier Munoz, Mario Pende, Guadalupe Sabio, David M Sabatini, Alejo Efeyan
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling. Nature communications 12 (1) (2021)
Ayelén M Santamans, Valle Montalvo-Romeral, Alfonso Mora, Juan Antonio López, Francisco González-Romero, Daniel Jimenez-Blasco, Elena Rodríguez, Aránzazu Pintor Chocano, Cristina Casanueva-Benítez, Rebecca Acin-Perez, Luis Leiva, Jordi Duran, Joan J Guinovart, Jesús Jiménez-Borreguero, José Antonio Enríquez, María Villlalba-Orero, Juan Pedro Bolaños, Patricia Aspichueta, Jesús Vázquez, Barbara Gonzalez-Teran, Guadalupe Sabio
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS biology 19 (11) (2021)
Elisa Manieri, Cintia Folgueira, María Elena Rodríguez, Luis Leiva-Vega, Laura Esteban-Lafuente, Chaobo Chen, Francisco Javier Cubero, Tamera Barrett, Julie Cavanagh-Kyros, Davide Seruggia, Alejandro Rosell, Fatima Sánchez-Cabo, Manuel Jose Gómez, Maria J Monte, Jose J G Marin, Roger J Davis, Alfonso Mora, Guadalupe Sabio
JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma. Proceedings of the National Academy of Sciences of the United States of America 117 (28) (2020)
Ana Victoria Lechuga-Vieco, Ana Latorre-Pellicer, Iain G Johnston, Gennaro Prota, Uzi Gileadi, Raquel Justo-Méndez, Rebeca Acín-Pérez, Raquel Martínez-de-Mena, Jose María Fernández-Toro, Daniel Jimenez-Blasco, Alfonso Mora, José Ángel Nicolás-Ávila, Demetrio Julián Santiago, Silvia Giuliana Priori, Juan Pedro Bolaños, Guadalupe Sabio, Luis Miguel Criado, Jesús Ruíz-Cabello, Vincenzo Cerundolo, Nick S Jones, José Antonio Enríquez
Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics. Science advances 6 (31) (2020)
Ivana Nikolic, Magdalena Leiva, Guadalupe Sabio
The role of stress kinases in metabolic disease. Nature reviews. Endocrinology 16 (12) (2020)
Rafael Romero-Becerra, Ayelén M Santamans, Cintia Folgueira, Guadalupe Sabio
p38 MAPK Pathway in the Heart: New Insights in Health and Disease. International journal of molecular sciences 21 (19) (2020)
Maria Crespo-Ruiz, Barbara Gonzalez-Teran, Ivana Nikolic, Alfonso Mora, Cintia Folgueira, Elena Rodríguez, Luis Leiva-Vega, Aránzazu Pintor-Chocano, Macarena Fernández-Chacón, Irene Ruiz-Garrido, Beatriz Cicuéndez, Antonia Tomás-Loba, Noelia Alonso Gonzalez, Ainoa Caballero-Molano, Daniel Beiroa, Lourdes Hernández-Cosido, Jorge L Torres, Norman J Kennedy, Roger J Davis, Rui Benedito, Miguel Marcos, Ruben Nogueiras, Andrés Hidalgo, Nuria Matesanz, Magdalena Leiva, Guadalupe Sabio
Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. eLife 9 (2020)
Elisa Manieri, Leticia Herrera-Melle, Alfonso Mora, Antonia Tomás-Loba, Luis Leiva-Vega, Delia I Fernández, Elena Rodríguez, Laura Morán, Lourdes Hernández-Cosido, Jorge L Torres, Luisa M Seoane, Francisco Javier Cubero, Miguel Marcos, Guadalupe Sabio
Adiponectin accounts for gender differences in hepatocellular carcinoma incidence. The Journal of experimental medicine 216 (5) (2019)
Nuria Matesanz, Ivana Nikolic, Magdalena Leiva, Marta Pulgarín-Alfaro, Ayelén M Santamans, Edgar Bernardo, Alfonso Mora, Leticia Herrera-Melle, Elena Rodríguez, Daniel Beiroa, Ainoa Caballero, Elena Martín-García, Rebeca Acín-Pérez, Lourdes Hernández-Cosido, Luis Leiva-Vega, Jorge L Torres, Francisco Centeno, Angel R Nebreda, José Antonio Enríquez, Rubén Nogueiras, Miguel Marcos, Guadalupe Sabio
p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS biology 16 (7) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Guadalupe Sabio