Andreas Lingel

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 11

Top Venues

Journal of medicinal chemistry

Journal of the American Chemical Society

Biochemistry

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Stefan Schütz, Christian Bergsdorf, Sandra Hänni-Holzinger, Andreas Lingel, Martin Renatus, Alvar D Gossert, Wolfgang Jahnke
Intrinsically Disordered Regions in the Transcription Factor MYC:MAX Modulate DNA Binding via Intramolecular Interactions. Biochemistry (2024)
Ulrich Hommel, Konstanze Hurth, Jean-Michel Rondeau, Anna Vulpetti, Daniela Ostermeier, Andreas Boettcher, Jacob Peter Brady, Michael Hediger, Sylvie Lehmann, Elke Koch, Anke Blechschmidt, Rina Yamamoto, Valentina Tundo Dottorello, Sandra Haenni-Holzinger, Christian Kaiser, Philipp Lehr, Andreas Lingel, Luca Mureddu, Christian Schleberger, Jutta Blank, Paul Ramage, Felix Freuler, Joerg Eder, Frédéric Bornancin
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β. Nature communications 14 (1) (2023)
Ying Huang, Martin Sendzik, Jeff Zhang, Zhenting Gao, Yongfeng Sun, Long Wang, Justin Gu, Kehao Zhao, Zhengtian Yu, Lijun Zhang, Qiong Zhang, Joachim Blanz, Zijun Chen, Valérie Dubost, Douglas Fang, Lijian Feng, Xingnian Fu, Michael Kiffe, Ling Li, Fangjun Luo, Xiao Luo, Yuan Mi, Prakash Mistry, David Pearson, Alessandro Piaia, Clemens Scheufler, Remi Terranova, Andreas Weiss, Jue Zeng, Hailong Zhang, Jiangwei Zhang, Mengxi Zhao, Michael P Dillon, Sebastien Jeay, Wei Qi, Jonathan Moggs, Carole Pissot Soldermann, En Li, Peter Atadja, Andreas Lingel, Counde Oyang
Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. Journal of medicinal chemistry 65 (7) (2022)
Edwige L Lorthiois, Marc Gerspacher, Kim S Beyer, Andrea Vaupel, Catherine Leblanc, Rowan Stringer, Andreas Weiss, Rainer Wilcken, Daniel A Guthy, Andreas Lingel, Claudio Bomio, Rainer Machauer, Pascal Rigollier, Johannes Ottl, Dorothee Arz, Pascal Bernet, Gaëlle Desjonqueres, Solene Dussauge, Malika Kazic-Legueux, Marie-Anne Lozac'h, Christophe Mura, Mickaël Sorge, Milen Todorov, Nicolas Warin, Florence Zink, Johannes Voshol, Frederic J Zecri, Richard C Sedrani, Nils Ostermann, Saskia M Brachmann, Simona Cotesta
JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS G12C for the Treatment of Solid Tumors. Journal of medicinal chemistry (2022)
Wooseok Han, Xiaolei Ma, Carl J Balibar, Christopher M Baxter Rath, Bret Benton, Alun Bermingham, Fergal Casey, Barbara Chie-Leon, Min-Kyu Cho, Andreas O Frank, Alexandra Frommlet, Chi-Min Ho, Patrick S Lee, Min Li, Andreas Lingel, Sylvia Ma, Hanne Merritt, Elizabeth Ornelas, Gianfranco De Pascale, Ramadevi Prathapam, Katherine R Prosen, Dita Rasper, Alexey Ruzin, William S Sawyer, Jacob Shaul, Xiaoyu Shen, Steven Shia, Micah Steffek, Sharadha Subramanian, Jason Vo, Feng Wang, Charles Wartchow, Tsuyoshi Uehara
Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Journal of the American Chemical Society 142 (9) (2020)
Andreas Lingel, Anna Vulpetti, Tony Reinsperger, Andrew Proudfoot, Regis Denay, Alexandra Frommlet, Christelle Henry, Ulrich Hommel, Alvar D Gossert, Burkhard Luy, Andreas O Frank
Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband 19 F NMR-Based Screening. Angewandte Chemie (International ed. in English) 59 (35) (2020)
Robert J Moreau, Colin K Skepper, Brent A Appleton, Anke Blechschmidt, Carl J Balibar, Bret M Benton, Joseph E Drumm, Brian Y Feng, Mei Geng, Cindy Li, Mika K Lindvall, Andreas Lingel, Yipin Lu, Mulugeta Mamo, Wosenu Mergo, Valery Polyakov, Thomas M Smith, Kenneth Takeoka, Kyoko Uehara, Lisha Wang, Jun-Rong Wei, Andrew H Weiss, Lili Xie, Wenjian Xu, Qiong Zhang, Javier de Vicente
Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria. Journal of medicinal chemistry 61 (8) (2018)
Colin K Skepper, Robert J Moreau, Brent A Appleton, Bret M Benton, Joseph E Drumm, Brian Y Feng, Mei Geng, Cheng Hu, Cindy Li, Andreas Lingel, Yipin Lu, Mulugeta Mamo, Wosenu Mergo, Mina Mostafavi, Christopher M Rath, Micah Steffek, Kenneth T Takeoka, Kyoko Uehara, Lisha Wang, Jun-Rong Wei, Lili Xie, Wenjian Xu, Qiong Zhang, Javier de Vicente
Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity. Journal of medicinal chemistry 61 (8) (2018)
Ying Huang, Jeff Zhang, Zhengtian Yu, Hailong Zhang, Youzhen Wang, Andreas Lingel, Wei Qi, Justin Gu, Kehao Zhao, Michael D Shultz, Long Wang, Xingnian Fu, Yongfeng Sun, Qiong Zhang, Xiangqing Jiang, Jiangwei Zhang, Chunye Zhang, Ling Li, Jue Zeng, Lijian Feng, Chao Zhang, Yueqin Liu, Man Zhang, Lijun Zhang, Mengxi Zhao, Zhenting Gao, Xianghui Liu, Douglas Fang, Haibing Guo, Yuan Mi, Tobias Gabriel, Michael P Dillon, Peter Atadja, Counde Oyang
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy. Journal of medicinal chemistry 60 (6) (2017)
Andrew Proudfoot, Dirksen E Bussiere, Andreas Lingel
High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. Journal of the American Chemical Society 139 (49) (2017)
Andreas Lingel, Martin Sendzik, Ying Huang, Michael D Shultz, John Cantwell, Michael P Dillon, Xingnian Fu, John Fuller, Tobias Gabriel, Justin Gu, Xiangqing Jiang, Ling Li, Fang Liang, Maureen McKenna, Wei Qi, Weijun Rao, Xijun Sheng, Wei Shu, James Sutton, Benjamin Taft, Long Wang, Jue Zeng, Hailong Zhang, Maya Zhang, Kehao Zhao, Mika Lindvall, Dirksen E Bussiere
Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase. Journal of medicinal chemistry 60 (1) (2017)

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Publication Activity (10 Years)

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Andreas Lingel