Anna Vulpetti

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

Nature communications

Journal of medicinal chemistry

Bioconjugate chemistry

ACS medicinal chemistry letters

Novartis Institutes for BioMedical Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Novartis Institutes for BioMedical Research Apr 01 2006

Switzerland

Senior Investigator :: Global Discovery Chemistry

Pharmacia & Upjohn Sep 15 1995 - Mar 31 2006

Italy

Principal Scientist :: Structural Chemistry

Publications

Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel A Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Luca Arista, Thomas Zoller, Thomas Radimerski, Claudio Thoma, Christina Hebach, William R Tschantz, Alexei S Karpov, Gregory J Hollingworth, Joseph A D'Alessio, Stephane Ferretti, Matthew T Burger
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates. Bioconjugate chemistry 35 (2) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Anna Vulpetti, Jean-Michel Rondeau, Marie-Hélène Bellance, Jutta Blank, Ralf Boesch, Andreas Boettcher, Frédéric Bornancin, Sylvia Buhr, Lauren E Connor, Christoph E Dumelin, Oliver Esser, Michael Hediger, Samuel Hintermann, Ulrich Hommel, Elke Koch, Guillaume Lapointe, Lukas Leder, Sylvie Lehmann, Philipp Lehr, Peter Meier, Lionel Muller, Daniela Ostermeier, Paul Ramage, Sihame Schiebel-Haddad, Alexander Baxter Smith, Aleksandar Stojanovic, Juraj Velcicky, Rina Yamamoto, Konstanze Hurth
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches. Journal of medicinal chemistry (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Anna Vulpetti, Jean-Michel Rondeau, Marie-Hélène Bellance, Jutta Blank, Ralf Boesch, Andreas Boettcher, Frédéric Bornancin, Sylvia Buhr, Lauren E Connor, Christoph E Dumelin, Oliver Esser, Michael Hediger, Samuel Hintermann, Ulrich Hommel, Elke Koch, Guillaume Lapointe, Lukas Leder, Sylvie Lehmann, Philipp Lehr, Peter Meier, Lionel Muller, Daniela Ostermeier, Paul Ramage, Sihame Schiebel-Haddad, Alexander Baxter Smith, Aleksandar Stojanovic, Juraj Velcicky, Rina Yamamoto, Konstanze Hurth
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches. Journal of medicinal chemistry 67 (10) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel A Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Luca Arista, Thomas Zoller, Thomas Radimerski, Claudio Thoma, Christina Hebach, William R Tschantz, Alexei S Karpov, Gregory J Hollingworth, Joseph A D'Alessio, Stephane Ferretti, Matthew T Burger
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates. Bioconjugate chemistry 35 (2) (2024)
Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel A Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Luca Arista, Thomas Zoller, Thomas Radimerski, Claudio Thoma, Christina Hebach, William R Tschantz, Alexei S Karpov, Gregory J Hollingworth, Joseph A D'Alessio, Stephane Ferretti, Matthew T Burger
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates. Bioconjugate chemistry 35 (2) (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Anna Vulpetti, Jean-Michel Rondeau, Marie-Hélène Bellance, Jutta Blank, Ralf Boesch, Andreas Boettcher, Frédéric Bornancin, Sylvia Buhr, Lauren E Connor, Christoph E Dumelin, Oliver Esser, Michael Hediger, Samuel Hintermann, Ulrich Hommel, Elke Koch, Guillaume Lapointe, Lukas Leder, Sylvie Lehmann, Philipp Lehr, Peter Meier, Lionel Muller, Daniela Ostermeier, Paul Ramage, Sihame Schiebel-Haddad, Alexander Baxter Smith, Aleksandar Stojanovic, Juraj Velcicky, Rina Yamamoto, Konstanze Hurth
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches. Journal of medicinal chemistry 67 (10) (2024)
Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel A Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Luca Arista, Thomas Zoller, Thomas Radimerski, Claudio Thoma, Christina Hebach, William R Tschantz, Alexei S Karpov, Gregory J Hollingworth, Joseph A D'Alessio, Stephane Ferretti, Matthew T Burger
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates. Bioconjugate chemistry (2024)
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic D Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R Thoma
Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications 15 (1) (2024)
Ulrich Hommel, Konstanze Hurth, Jean-Michel Rondeau, Anna Vulpetti, Daniela Ostermeier, Andreas Boettcher, Jacob Peter Brady, Michael Hediger, Sylvie Lehmann, Elke Koch, Anke Blechschmidt, Rina Yamamoto, Valentina Tundo Dottorello, Sandra Haenni-Holzinger, Christian Kaiser, Philipp Lehr, Andreas Lingel, Luca Mureddu, Christian Schleberger, Jutta Blank, Paul Ramage, Felix Freuler, Joerg Eder, Frédéric Bornancin
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β. Nature communications 14 (1) (2023)
Klemens Hoegenauer, Shaojian An, Jake Axford, Christina Benander, Christian Bergsdorf, Josephine Botsch, Suzanne Chau, César Fernández, Scott Gleim, Ulrich Hassiepen, Juerg Hunziker, Emilie Joly, Aramis Keller, Sandra Lopez Romero, Robert Maher, Anne-Sophie Mangold, Craig Mickanin, Manuel Mihalic, Philippe Neuner, Andrew W Patterson, Francesca Perruccio, Silvio Roggo, Julien Scesa, Martin Schröder, Dojna Shkoza, Binh Thai, Anna Vulpetti, Martin Renatus, John S Reece-Hoyes
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. ACS medicinal chemistry letters 14 (12) (2023)
Anna Vulpetti, Philipp Holzer, Niko Schmiedeberg, Patricia Imbach-Weese, Carole Pissot Soldermann, Gregory J Hollingworth, Thomas Radimerski, Claudio R Thoma, Therese-Marie Stachyra, Matthias Wojtynek, Magdalena Maschlej, Suzanne Chau, Ansgar Schuffenhauer, César Fernández, Martin Schröder, Martin Renatus
Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. ACS medicinal chemistry letters 14 (7) (2023)
Klemens Hoegenauer, Shaojian An, Jake Axford, Christina Benander, Christian Bergsdorf, Josephine Botsch, Suzanne Chau, César Fernández, Scott Gleim, Ulrich Hassiepen, Juerg Hunziker, Emilie Joly, Aramis Keller, Sandra Lopez Romero, Robert Maher, Anne-Sophie Mangold, Craig Mickanin, Manuel Mihalic, Philippe Neuner, Andrew W Patterson, Francesca Perruccio, Silvio Roggo, Julien Scesa, Martin Schröder, Dojna Shkoza, Binh Thai, Anna Vulpetti, Martin Renatus, John S Reece-Hoyes
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. ACS medicinal chemistry letters 14 (12) (2023)
Patrick Penner, Anna Vulpetti
QM assisted ML for 19 F NMR chemical shift prediction. Journal of computer-aided molecular design 38 (1) (2023)
Jean Quancard, Anna Vulpetti, Anders Bach, Brian Cox, Stéphanie M Guéret, Ingo V Hartung, Hannes F Koolman, Stefan A Laufer, Josef Messinger, Gianluca Sbardella, Russell Craft
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation. ChemMedChem (2023)
Anna Vulpetti, Andreas Lingel, Claudio Dalvit, Nikolaus Schiering, Lukas Oberer, Christelle Henry, Yipin Lu
Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19 F NMR Binding Assay with Predicted 19 F NMR Chemical Shifts. ChemMedChem 17 (13) (2022)
Anna Vulpetti, Claudio Dalvit
Hydrogen Bond Acceptor Propensity of Different Fluorine Atom Types: An Analysis of Experimentally and Computationally Derived Parameters. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (34) (2021)
Daniela Angst, François Gessier, Philipp Janser, Anna Vulpetti, Rudolf Wälchli, Christian Beerli, Amanda Littlewood-Evans, Janet Dawson, Barbara Nuesslein-Hildesheim, Grazyna Wieczorek, Sascha Gutmann, Clemens Scheufler, Alexandra Hinniger, Alfred Zimmerlin, Enrico G Funhoff, Robert Pulz, Bruno Cenni
Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase. Journal of medicinal chemistry 63 (10) (2020)
Andreas Lingel, Anna Vulpetti, Tony Reinsperger, Andrew Proudfoot, Regis Denay, Alexandra Frommlet, Christelle Henry, Ulrich Hommel, Alvar D Gossert, Burkhard Luy, Andreas O Frank
Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband 19 F NMR-Based Screening. Angewandte Chemie (International ed. in English) 59 (35) (2020)
Rajeshri G Karki, James Powers, Nello Mainolfi, Karen Anderson, David B Belanger, Donglei Liu, Nan Ji, Keith Jendza, Christine F Gelin, Aengus Mac Sweeney, Catherine Solovay, Omar Delgado, Maura Crowley, Sha-Mei Liao, Upendra A Argikar, Stefanie Flohr, Laura R La Bonte, Edwige L Lorthiois, Anna Vulpetti, Ann Brown, Debby Long, Melissa Prentiss, Nathalie Gradoux, Andrea de Erkenez, Frederic Cumin, Christopher M Adams, Bruce Jaffee, Muneto Mogi
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway. Journal of medicinal chemistry 62 (9) (2019)
Claudio Dalvit, Anna Vulpetti
Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects. Journal of medicinal chemistry 62 (5) (2018)
David A Carcache, Anna Vulpetti, Joerg Kallen, Henri Mattes, David Orain, Rowan Stringer, Eric Vangrevelinghe, Romain M Wolf, Klemens Kaupmann, Johannes Ottl, Janet Dawson, Nigel G Cooke, Klemens Hoegenauer, Andreas Billich, Juergen Wagner, Christine Guntermann, Samuel Hintermann
Optimizing a Weakly Binding Fragment into a Potent RORγt Inverse Agonist with Efficacy in an in Vivo Inflammation Model. Journal of medicinal chemistry 61 (15) (2018)
Anna Vulpetti, Stefan Randl, Simon Rüdisser, Nils Ostermann, Paul Erbel, Aengus Mac Sweeney, Thomas Zoller, Bahaa Salem, Bernd Gerhartz, Frederic Cumin, Ulrich Hommel, Claudio Dalvit, Edwige Lorthiois, Jürgen Maibaum
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors. Journal of medicinal chemistry 60 (5) (2017)
Edwige L Lorthiois, Karen Anderson, Anna Vulpetti, Olivier Rogel, Frederic Cumin, Nils Ostermann, Stefan Steinbacher, Aengus Mac Sweeney, Omar Delgado, Sha-Mei Liao, Stefan Randl, Simon Rüdisser, Solene Dussauge, Kamal Fettis, Laurence Kieffer, Andrea de Erkenez, Louis Yang, Constanze Hartwieg, Upendra A Argikar, Laura R La Bonte, Ronald Newton, Viral Kansara, Stefanie Flohr, Ulrich Hommel, Bruce Jaffee, Jürgen Maibaum
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo. Journal of medicinal chemistry 60 (13) (2017)
Claudio Dalvit, Anna Vulpetti
Weak Intermolecular Hydrogen Bonds with Fluorine: Detection and Implications for Enzymatic/Chemical Reactions, Chemical Properties, and Ligand/Protein Fluorine NMR Screening. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (22) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Anna Vulpetti