Andrew David Smith (Andrew D Smith)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Topics

Molecular Docking

Breast Cancer Cells

Top Venues

Angewandte Chemie (International ed. in English)

Chemical science

Organic letters

Chemical communications (Cambridge, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Alastair J Nimmo, Kevin Kasten, George White, Julia Roeterdink, Aidan P McKay, David Bradford Cordes, Andrew David Smith
One-Pot Access to Functionalised Malamides via Organocatalytic Enantioselective Formation of Spirocyclic β-Lactone-Oxindoles and Double Ring-Opening. Molecules (Basel, Switzerland) 29 (15) (2024)
Haoxiang Zhu, Alejandro Manchado, Abdikani Omar Farah, Aidan P McKay, David Bradford Cordes, Paul Ha-Yeon Cheong, Kevin Kasten, Andrew David Smith
Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution of Tetra-substituted Morpholinone and Benzoxazinone Lactols. Angewandte Chemie (International ed. in English) (2024)
Aífe Conboy, Alister S Goodfellow, Kevin Kasten, Joanne Dunne, David Bradford Cordes, Michael Bűhl, Andrew David Smith
De-epimerizing DyKAT of β-lactones generated by isothiourea-catalysed enantioselective [2 + 2] cycloaddition. Chemical science 15 (23) (2024)
Zhanyu Zhou, Kevin Kasten, Tengfei Kang, David Bradford Cordes, Andrew David Smith
Enantioselective Synthesis in Continuous Flow: Polymer-Supported Isothiourea-Catalyzed Enantioselective Michael Addition-Cyclization with α-Azol-2-ylacetophenones. Organic process research & development 28 (5) (2024)
Alastair J Nimmo, Kevin Kasten, George White, Julia Roeterdink, Aidan P McKay, David Bradford Cordes, Andrew David Smith
One-Pot Access to Functionalised Malamides via Organocatalytic Enantioselective Formation of Spirocyclic β-Lactone-Oxindoles and Double Ring-Opening. Molecules (Basel, Switzerland) 29 (15) (2024)
Aífe Conboy, Alister S Goodfellow, Kevin Kasten, Joanne Dunne, David Bradford Cordes, Michael Bűhl, Andrew David Smith
De-epimerizing DyKAT of β-lactones generated by isothiourea-catalysed enantioselective [2 + 2] cycloaddition. Chemical science 15 (23) (2024)
Zhanyu Zhou, Kevin Kasten, Tengfei Kang, David Bradford Cordes, Andrew David Smith
Enantioselective Synthesis in Continuous Flow: Polymer-Supported Isothiourea-Catalyzed Enantioselective Michael Addition-Cyclization with α-Azol-2-ylacetophenones. Organic process research & development 28 (5) (2024)
Haoxiang Zhu, Alejandro Manchado, Abdikani Omar Farah, Aidan P McKay, David Bradford Cordes, Paul Ha-Yeon Cheong, Kevin Kasten, Andrew David Smith
Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution of Tetra-substituted Morpholinone and Benzoxazinone Lactols. Angewandte Chemie (International ed. in English) 63 (37) (2024)
Paul M D A Ewing, Pankaj Kumar Majhi, Callum Prentice, Claire M Young, Karlotta van Rees, Polly L Arnold, Eli Zysman-Colman, Andrew David Smith
α-Phenylthioaldehydes for the effective generation of acyl azolium and azolium enolate intermediates. Chemical science 15 (24) (2024)
Shubham K Agrawal, Pankaj K Majhi, Alister S Goodfellow, Raj Kumar Tak, David Bradford Cordes, Aidan P McKay, Kevin Kasten, Michael Bühl, Andrew David Smith
Synthesis of Tetra-Substituted 3-Hydroxyphthalide Esters by Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution. Angewandte Chemie (International ed. in English) 63 (37) (2024)
Paul M D A Ewing, Pankaj Kumar Majhi, Callum Prentice, Claire M Young, Karlotta van Rees, Polly L Arnold, Eli Zysman-Colman, Andrew David Smith
α-Phenylthioaldehydes for the effective generation of acyl azolium and azolium enolate intermediates. Chemical science 15 (24) (2024)
Shubham K Agrawal, Pankaj K Majhi, Alister S Goodfellow, Raj Kumar Tak, David Bradford Cordes, Aidan P McKay, Kevin Kasten, Michael Bühl, Andrew David Smith
Synthesis of Tetra-Substituted 3-Hydroxyphthalide Esters by Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution. Angewandte Chemie (International ed. in English) (2024)
Ding Yuan, Alister S Goodfellow, Kevin Kasten, Zhuan Duan, Tengfei Kang, David Bradford Cordes, Aidan P McKay, Michael Bűhl, Gregory R Boyce, Andrew David Smith
Understanding divergent substrate stereoselectivity in the isothiourea-catalysed conjugate addition of cyclic α-substituted β-ketoesters to α,β-unsaturated aryl esters. Chemical science 14 (48) (2023)
Alastair J Nimmo, Jacqueline Bitai, Claire M Young, Calum McLaughlin, Alexandra M Z Slawin, David Bradford Cordes, Andrew David Smith
Enantioselective isothiourea-catalysed reversible Michael addition of aryl esters to 2-benzylidene malononitriles. Chemical science 14 (27) (2023)
Grant J Sherborne, Coura Diène, Paul Kemmitt, Andrew David Smith
Access to a Diverse Array of Bridged Benzo[1,5]oxazocine and Benzo[1,4]diazepine Structures. Organic letters (2023)
Callum Prentice, Alice E Martin, James Morrison, Andrew David Smith, Eli Zysman-Colman
Benzophenone as a cheap and effective photosensitizer for the photocatalytic synthesis of dimethyl cubane-1,4-dicarboxylate. Organic & biomolecular chemistry (2023)
Ding Yuan, Alister S Goodfellow, Kevin Kasten, Zhuan Duan, Tengfei Kang, David Bradford Cordes, Aidan P McKay, Michael Bűhl, Gregory R Boyce, Andrew David Smith
Understanding divergent substrate stereoselectivity in the isothiourea-catalysed conjugate addition of cyclic α-substituted β-ketoesters to α,β-unsaturated aryl esters. Chemical science 14 (48) (2023)
Callum Prentice, James Morrison, Eli Zysman-Colman, Andrew David Smith
Dual NHC/photoredox catalytic synthesis of 1,4-diketones using an MR-TADF photocatalyst (DiKTa). Chemical communications (Cambridge, England) (2022)
Arianna Brandolese, Mark D Greenhalgh, Titouan Desrues, Xueyang Liu, Shen Qu, Cyril Bressy, Andrew David Smith
Horeau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow. Organic & biomolecular chemistry 19 (16) (2022)
Jiayun Zhu, Inmaculada Moreno, Peter Quinn, Dmitry S Yufit, Lijuan Song, Claire M Young, Zhuan Duan, Andrew R Tyler, Paul G Waddell, Michael John Hall, Michael R Probert, Andrew David Smith, AnnMarie C O'Donoghue
The Role of the Fused Ring in Bicyclic Triazolium Organocatalysts: Kinetic, X-ray, and DFT Insights. The Journal of organic chemistry 87 (6) (2022)
Grant J Sherborne, Paul Kemmitt, Callum Prentice, Eli Zysman-Colman, Andrew David Smith, Charlene Fallan
Visible Light-Mediated Cyclisation Reaction for the Synthesis of Highly-Substituted Tetrahydroquinolines and Quinolines. Angewandte Chemie (International ed. in English) (2022)
Jerson E Lapetaje, Claire M Young, Chang Shu, Andrew David Smith
Isothiourea-catalyzed formal enantioselective conjugate addition of benzophenone imines to β-fluorinated α,β-unsaturated esters. Chemical communications (Cambridge, England) 58 (49) (2022)
Yihong Wang, Claire M Young, Honglei Liu, Will C Hartley, Max Wienhold, David B Cordes, Alexandra M Z Slawin, Andrew David Smith
A Desilylative Approach to Alkyl Substituted C(1)-Ammonium Enolates: Application in Enantioselective [2+2] Cycloadditions. Angewandte Chemie (International ed. in English) 61 (38) (2022)
Yusra Abdelhamid, Kevin Kasten, Joanne Dunne, Will C Hartley, Claire M Young, David Bradford Cordes, Alexandra M Z Slawin, Sean Ng, Andrew David Smith
Isothiourea-Catalyzed [2 + 2] Cycloaddition of C(1)-Ammonium Enolates and N -Alkyl Isatins. Organic letters 24 (29) (2022)
Zhuan Duan, Claire M Young, Jiayun Zhu, Alexandra M Z Slawin, AnnMarie C O'Donoghue, Andrew David Smith
Rate and equilibrium constants for the addition of triazolium salt derived N-heterocyclic carbenes to heteroaromatic aldehydes. Chemical science 14 (1) (2022)
Roberto Del Río-Rodríguez, Matthew T Westwood, Marina Sicignano, Martin Juhl, José A Fernández-Salas, José Alemán, Andrew David Smith
Isothiourea-catalysed enantioselective radical conjugate addition under batch and flow conditions. Chemical communications (Cambridge, England) 58 (52) (2022)
Gregory R Boyce, Stefania F Musolino, Jianing Yang, Andrew David Smith, James E Taylor
Arylboronic Acid-Catalyzed Racemization of Secondary and Tertiary Alcohols. The Journal of organic chemistry 87 (19) (2022)
Jiufeng Wu, Claire M Young, Amy A Watts, Alexandra M Z Slawin, Gregory R Boyce, Michael Bühl, Andrew David Smith
Isothiourea-Catalyzed Enantioselective Michael Addition of Malonates to α,β-Unsaturated Aryl Esters. Organic letters 24 (22) (2022)
Jacqueline Bitai, Alastair J Nimmo, Alexandra M Z Slawin, Andrew David Smith
Cooperative Palladium/Isothiourea Catalyzed Enantioselective Formal (3+2) Cycloaddition of Vinylcyclopropanes and α,β-Unsaturated Esters. Angewandte Chemie (International ed. in English) 61 (25) (2022)
Feng Zhao, Chang Shu, Claire M Young, Cameron Carpenter-Warren, Alexandra M Z Slawin, Andrew David Smith
Enantioselective Synthesis of α-Aryl-β2 -Amino-Esters by Cooperative Isothiourea and Brønsted Acid Catalysis. Angewandte Chemie (International ed. in English) 60 (21) (2021)
Richard S Massey, Jacob Murray, Christopher J Collett, Jiayun Zhu, Andrew David Smith, AnnMarie C O'Donoghue
Kinetic and structure-activity studies of the triazolium ion-catalysed benzoin condensation. Organic & biomolecular chemistry 19 (2) (2021)
Jude N Arokianathar, Will C Hartley, Calum McLaughlin, Mark D Greenhalgh, Darren Stead, Sean Ng, Alexandra M Z Slawin, Andrew David Smith
Isothiourea-Catalyzed Enantioselective α-Alkylation of Esters via 1,6-Conjugate Addition to para-Quinone Methides. Molecules (Basel, Switzerland) 26 (21) (2021)
Calum McLaughlin, Jacqueline Bitai, Lydia J Barber, Alexandra M Z Slawin, Andrew David Smith
Catalytic enantioselective synthesis of 1,4-dihydropyridines via the addition of C(1)-ammonium enolates to pyridinium salts. Chemical science 12 (36) (2021)
Elizabeth S Munday, Markas A Grove, Taisiia Feoktistova, Alexander C Brueckner, Daniel M Walden, Claire M Young, Alexandra M Z Slawin, Andrew D Campbell, Paul Ha-Yeon Cheong, Andrew David Smith
Isothiourea-Catalyzed Atropselective Acylation of Biaryl Phenols via Sequential Desymmetrization/Kinetic Resolution. Angewandte Chemie (International ed. in English) 59 (20) (2020)
Shuyue Zhang, Mark D Greenhalgh, Alexandra M Z Slawin, Andrew David Smith
Tandem sequential catalytic enantioselective synthesis of highly-functionalised tetrahydroindolizine derivatives. Chemical science 11 (15) (2020)
Honglei Liu, Alexandra M Z Slawin, Andrew David Smith
Isothiourea-Catalyzed Enantioselective Synthesis of Tetrahydro-α-carbolinones. Organic letters 22 (4) (2020)
Alyn T Davies, Mark D Greenhalgh, Alexandra M Z Slawin, Andrew David Smith
NHC-catalyzed enantioselective synthesis of β-trifluoromethyl-β-hydroxyamides. Beilstein journal of organic chemistry 16 (2020)
Calum McLaughlin, Andrew David Smith
Generation and Reactivity of C(1)-Ammonium Enolates by Using Isothiourea Catalysis. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (5) (2020)
Callum Prentice, James Morrisson, Andrew David Smith, Eli Zysman-Colman
Recent developments in enantioselective photocatalysis. Beilstein journal of organic chemistry 16 (2020)
Shen Qu, Samuel M Smith, Víctor Laina-Martín, Rifahath M Neyyappadath, Mark D Greenhalgh, Andrew David Smith
Isothiourea-Catalyzed Acylative Kinetic Resolution of Tertiary α-Hydroxy Esters. Angewandte Chemie (International ed. in English) 59 (38) (2020)
Claire M Young, Alex Elmi, Dominic J Pascoe, Rylie K Morris, Calum McLaughlin, Andrew M Woods, Aileen B Frost, Alix de la Houpliere, Kenneth B Ling, Terry K Smith, Alexandra M Z Slawin, Patrick H Willoughby, Scott L Cockroft, Andrew David Smith
The Importance of 1,5-Oxygen⋅⋅⋅Chalcogen Interactions in Enantioselective Isochalcogenourea Catalysis. Angewandte Chemie (International ed. in English) 59 (9) (2020)
Shen Qu, Mark D Greenhalgh, Andrew David Smith
Isothiourea-Catalysed Regioselective Acylative Kinetic Resolution of Axially Chiral Biaryl Diols. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (11) (2019)
Diego-Javier Barrios Antúnez, Mark D Greenhalgh, Alexander C Brueckner, Daniel M Walden, Pilar Elías-Rodríguez, Patrick Roberts, Benjamin G Young, Thomas H West, Alexandra M Z Slawin, Paul Ha-Yeon Cheong, Andrew David Smith
Catalytic enantioselective synthesis of perfluoroalkyl-substituted β-lactones via a concerted asynchronous [2 + 2] cycloaddition: a synthetic and computational study. Chemical science 10 (24) (2019)
Anastassia Matviitsuk, Mark D Greenhalgh, James E Taylor, Xuan B Nguyen, David Bradford Cordes, Alexandra M Z Slawin, David W Lupton, Andrew David Smith
Unanticipated Silyl Transfer in Enantioselective α,β-Unsaturated Acyl Ammonium Catalysis Using Silyl Nitronates. Organic letters 22 (1) (2019)
Calum McLaughlin, Alexandra M Z Slawin, Andrew David Smith
Base-free Enantioselective C(1)-Ammonium Enolate Catalysis Exploiting Aryloxides: A Synthetic and Mechanistic Study. Angewandte Chemie (International ed. in English) 58 (42) (2019)
Chang Shu, Honglei Liu, Alexandra M Z Slawin, Cameron Carpenter-Warren, Andrew David Smith
Isothiourea-catalysed enantioselective Michael addition of N-heterocyclic pronucleophiles to α,β-unsaturated aryl esters. Chemical science 11 (1) (2019)
Polly L Arnold, Ryan W F Kerr, Catherine E Weetman, Scott R Docherty, Julia Rieb, Faye L Cruickshank, Kai Wang, Christian Jandl, Max W McMullon, Alexander Pöthig, Fritz E Kühn, Andrew David Smith
Selective and catalytic carbon dioxide and heteroallene activation mediated by cerium N-heterocyclic carbene complexes. Chemical science 9 (42) (2018)
John D Parkin, Ross Chisholm, Aileen B Frost, Richard G Bailey, Andrew David Smith, Georg Hähner
Direct Organocatalytic Enantioselective Functionalization of SiOx Surfaces. Angewandte Chemie (International ed. in English) 57 (30) (2018)
Danila Gasperini, Mark D Greenhalgh, Rehan Imad, Shezaib Siddiqui, Anum Malik, Fizza Arshad, Muhammad Iqbal Choudhary, Abdullah M Al-Majid, David B Cordes, Alexandra M Z Slawin, Steven P Nolan, Andrew David Smith
Chiral AuI - and AuIII -Isothiourea Complexes: Synthesis, Characterization and Application. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (4) (2018)
Mark D Greenhalgh, Samuel M Smith, Daniel M Walden, James E Taylor, Zamira Brice, Emily R T Robinson, Charlene Fallan, David B Cordes, Alexandra M Z Slawin, H Camille Richardson, Markas A Grove, Paul Ha-Yeon Cheong, Andrew David Smith
A C=O⋅⋅⋅Isothiouronium Interaction Dictates Enantiodiscrimination in Acylative Kinetic Resolutions of Tertiary Heterocyclic Alcohols. Angewandte Chemie (International ed. in English) 57 (12) (2018)
Shuyue Zhang, James E Taylor, Alexandra M Z Slawin, Andrew David Smith
Isothiourea-Catalyzed Enantioselective Functionalization of 2-Pyrrolyl Acetic Acid: Two-Step Synthesis of Stereodefined Dihydroindolizinones. Organic letters 20 (17) (2018)
Mark D Greenhalgh, Shen Qu, Alexandra M Z Slawin, Andrew David Smith
Multiple roles of aryloxide leaving groups in enantioselective annulations employing α,β-unsaturated acyl ammonium catalysis. Chemical science 9 (21) (2018)
Rifahath M Neyyappadath, David Bradford Cordes, Alexandra M Z Slawin, Andrew David Smith
6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis. Chemical communications (Cambridge, England) 53 (17) (2018)
Anastassia Matviitsuk, Mark D Greenhalgh, Diego-Javier Barrios Antúnez, Alexandra M Z Slawin, Andrew David Smith
Aryloxide-Facilitated Catalyst Turnover in Enantioselective α,β-Unsaturated Acyl Ammonium Catalysis. Angewandte Chemie (International ed. in English) 56 (40) (2017)
Stéphanie S M Spoehrle, Thomas H West, James E Taylor, Alexandra M Z Slawin, Andrew David Smith
Tandem Palladium and Isothiourea Relay Catalysis: Enantioselective Synthesis of α-Amino Acid Derivatives via Allylic Amination and [2,3]-Sigmatropic Rearrangement. Journal of the American Chemical Society 139 (34) (2017)
Thomas H West, Daniel M Walden, James E Taylor, Alexander C Brueckner, Ryne C Johnston, Paul Ha-Yeon Cheong, Guy C Lloyd Jones, Andrew David Smith
Catalytic Enantioselective [2,3]-Rearrangements of Allylic Ammonium Ylides: A Mechanistic and Computational Study. Journal of the American Chemical Society 139 (12) (2017)
Kevin Kasten, Alexandra M Z Slawin, Andrew David Smith
Enantioselective Synthesis of β-Fluoro-β-aryl-α-aminopentenamides by Organocatalytic [2,3]-Sigmatropic Rearrangement. Organic letters 19 (19) (2017)