Organic process research & development

Keyphrases

Publications

volume 28, number 1, 2024

Shohei Fukuda, Kanako Kondo, Shoji Fukumoto, Norimichi Takenaka, Osamu Uchikawa, Itsuro Yoshida
Correction to " N -Nitrosodimethylamine Formation in Metformin Drug Products by the Reaction of Dimethylamine and Atmospheric NO 2 ". Organic process research & development 28 (1) (2024)

volume 28, number 2, 2024

Andrew Fox, Liam T Ball
Development and Scale-Up of a New Sulfone-Based Bismacycle as a Universal Precursor for Bi(V)-Mediated Electrophilic Arylation. Organic process research & development 28 (2) (2024)
Andrew Fox, Liam T Ball
Development and Scale-Up of a New Sulfone-Based Bismacycle as a Universal Precursor for Bi(V)-Mediated Electrophilic Arylation. Organic process research & development 28 (2) (2024)

volume 28, number 4, 2024

Bhavik A Mehta, Ekaterina Gramadnikova, Cameron J Brown, Niall A Mitchell, Sara Ottoboni
Integrated Filtration and Washing Modeling: Optimization of Impurity Rejection for Filtration and Washing of Active Pharmaceutical Ingredients. Organic process research & development 28 (4) (2024)
Pankaj V Khairnar, John M Saathoff, Daniel W Cook, Samuel R Hochstetler, Urvish Pandya, Stephen J Robinson, Vijay Satam, Kai O Donsbach, B Frank Gupton, Li-Mei Jin, Charles S Shanahan
Practical Synthesis of 6-Amino-1-hydroxy-2,1-benzoxaborolane: A Key Intermediate of DNDI-6148. Organic process research & development 28 (4) (2024)
Bhavik A Mehta, Ekaterina Gramadnikova, Cameron J Brown, Niall A Mitchell, Sara Ottoboni
Integrated Filtration and Washing Modeling: Optimization of Impurity Rejection for Filtration and Washing of Active Pharmaceutical Ingredients. Organic process research & development 28 (4) (2024)
Cláudia Bento, Marianna Katz, Maria M M Santos, Carlos A M Afonso
Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol. Organic process research & development 28 (4) (2024)
Pankaj V Khairnar, John M Saathoff, Daniel W Cook, Samuel R Hochstetler, Urvish Pandya, Stephen J Robinson, Vijay Satam, Kai O Donsbach, B Frank Gupton, Li-Mei Jin, Charles S Shanahan
Practical Synthesis of 6-Amino-1-hydroxy-2,1-benzoxaborolane: A Key Intermediate of DNDI-6148. Organic process research & development 28 (4) (2024)
Hui Xiao, Yanyue Feng, William R F Goundry, Staffan Karlsson
Organic Solvent Nanofiltration in Pharmaceutical Applications. Organic process research & development 28 (4) (2024)
Hui Xiao, Yanyue Feng, William R F Goundry, Staffan Karlsson
Organic Solvent Nanofiltration in Pharmaceutical Applications. Organic process research & development 28 (4) (2024)
Hanuman P Kalmode, Ongolu Ravikumar, Dinesh J Paymode, John Bachert, Justina M Burns, Rodger W Stringham, Sarah L Bliese, Ryan C Nelson
A Tandem Ring Closure and Nitrobenzene Reduction with Sulfide Provides an Improved Route to an Important Intermediate for the Anti-Tuberculosis Drug Candidate Sutezolid. Organic process research & development 28 (4) (2024)
Hanuman P Kalmode, Ongolu Ravikumar, Dinesh J Paymode, John Bachert, Justina M Burns, Rodger W Stringham, Sarah L Bliese, Ryan C Nelson
A Tandem Ring Closure and Nitrobenzene Reduction with Sulfide Provides an Improved Route to an Important Intermediate for the Anti-Tuberculosis Drug Candidate Sutezolid. Organic process research & development 28 (4) (2024)
Cláudia Bento, Marianna Katz, Maria M M Santos, Carlos A M Afonso
Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol. Organic process research & development 28 (4) (2024)

volume 28, number 5, 2024

Zhanyu Zhou, Kevin Kasten, Tengfei Kang, David Bradford Cordes, Andrew David Smith
Enantioselective Synthesis in Continuous Flow: Polymer-Supported Isothiourea-Catalyzed Enantioselective Michael Addition-Cyclization with α-Azol-2-ylacetophenones. Organic process research & development 28 (5) (2024)
Matthew D Edwards, Matthew T Pratley, Charles M Gordon, Rodolfo Inêz Teixeira, Hamza Ali, Irfhan Mahmood, Reece Lester, Ashley Love, Johannes G H Hermens, Thomas Freese, Ben L Feringa, Martyn Poliakoff, Michael W George
Process Intensification of the Continuous Synthesis of Bio-Derived Monomers for Sustainable Coatings Using a Taylor Vortex Flow Reactor. Organic process research & development 28 (5) (2024)
Zhanyu Zhou, Kevin Kasten, Tengfei Kang, David Bradford Cordes, Andrew David Smith
Enantioselective Synthesis in Continuous Flow: Polymer-Supported Isothiourea-Catalyzed Enantioselective Michael Addition-Cyclization with α-Azol-2-ylacetophenones. Organic process research & development 28 (5) (2024)
Matthew D Edwards, Matthew T Pratley, Charles M Gordon, Rodolfo Inêz Teixeira, Hamza Ali, Irfhan Mahmood, Reece Lester, Ashley Love, Johannes G H Hermens, Thomas Freese, Ben L Feringa, Martyn Poliakoff, Michael W George
Process Intensification of the Continuous Synthesis of Bio-Derived Monomers for Sustainable Coatings Using a Taylor Vortex Flow Reactor. Organic process research & development 28 (5) (2024)
Michelle-Rose Ryan, Denis Lynch, Stuart G Collins, Anita R Maguire
Selective Thermal Deprotection of N -Boc Protected Amines in Continuous Flow. Organic process research & development 28 (5) (2024)
Jack J Bennett, Paul V Murphy
Flow Chemistry for Synthesis of 2-(C-Glycosyl)acetates from Pyranoses via Tandem Wittig and Michael Reactions. Organic process research & development 28 (5) (2024)
Ursina Gnädinger, Dario Poier, Claudio Trombini, Michal Dabros, Roger Marti
Development of Lab-Scale Continuous Stirred-Tank Reactor as Flow Process Tool for Oxidation Reactions Using Molecular Oxygen. Organic process research & development 28 (5) (2024)
Ursina Gnädinger, Dario Poier, Claudio Trombini, Michal Dabros, Roger Marti
Development of Lab-Scale Continuous Stirred-Tank Reactor as Flow Process Tool for Oxidation Reactions Using Molecular Oxygen. Organic process research & development 28 (5) (2024)
James Daglish, A John Blacker, Gregory de Boer, Stephen J Russell, Muhammad Tausif, David R J Hose, Anna R Parsons, Alex Crampton, Nikil Kapur
A Coalescing Filter for Liquid-Liquid Separation and Multistage Extraction in Continuous-Flow Chemistry. Organic process research & development 28 (5) (2024)
James Daglish, A John Blacker, Gregory de Boer, Stephen J Russell, Muhammad Tausif, David R J Hose, Anna R Parsons, Alex Crampton, Nikil Kapur
A Coalescing Filter for Liquid-Liquid Separation and Multistage Extraction in Continuous-Flow Chemistry. Organic process research & development 28 (5) (2024)
Michelle-Rose Ryan, Denis Lynch, Stuart G Collins, Anita R Maguire
Selective Thermal Deprotection of N -Boc Protected Amines in Continuous Flow. Organic process research & development 28 (5) (2024)
Jack J Bennett, Paul V Murphy
Flow Chemistry for Synthesis of 2-(C-Glycosyl)acetates from Pyranoses via Tandem Wittig and Michael Reactions. Organic process research & development 28 (5) (2024)

volume 28, number 7, 2024

Sayan Pal, Arun Pankajakshan, Maximilian Otto Besenhard, Nicholas Snead, Juan Almeida, Shorooq Abukhamees, Duncan Craig, Federico Galvanin, Asterios Gavriilidis, Luca Mazzei
Automated Continuous Crystallization Platform with Real-Time Particle Size Analysis via Laser Diffraction. Organic process research & development 28 (7) (2024)
Sayan Pal, Arun Pankajakshan, Maximilian Otto Besenhard, Nicholas Snead, Juan Almeida, Shorooq Abukhamees, Duncan Craig, Federico Galvanin, Asterios Gavriilidis, Luca Mazzei
Automated Continuous Crystallization Platform with Real-Time Particle Size Analysis via Laser Diffraction. Organic process research & development 28 (7) (2024)

volume 28, number 8, 2024

Daryl Guthrie, John M Saathoff, Rajkumar Lalji Sahani, Aline Nunes De Souza, Daniel W Cook, Samuel R Hochstetler, Justina M Burns, Roudabeh Sadat Moazeni-Pourasil, Janie Wierzbicki, Saeed Ahmad, G Michael Laidlaw, B Frank Gupton, Charles S Shanahan, Douglas A Klumpp, Li-Mei Jin
Synthetic Process Development of ( R )-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block. Organic process research & development 28 (8) (2024)
Ruairi Bannon, Gary Morrison, Megan Smyth, Thomas S Moody, Scott Wharry, Philippe M C Roth, Guillaume Gauron, Marcus Baumann
Continuous Flow Approach for Benzylic Photo-oxidations Using Compressed Air. Organic process research & development 28 (8) (2024)
Daryl Guthrie, John M Saathoff, Rajkumar Lalji Sahani, Aline Nunes De Souza, Daniel W Cook, Samuel R Hochstetler, Justina M Burns, Roudabeh Sadat Moazeni-Pourasil, Janie Wierzbicki, Saeed Ahmad, G Michael Laidlaw, B Frank Gupton, Charles S Shanahan, Douglas A Klumpp, Li-Mei Jin
Synthetic Process Development of ( R )-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block. Organic process research & development 28 (8) (2024)
Ruairi Bannon, Gary Morrison, Megan Smyth, Thomas S Moody, Scott Wharry, Philippe M C Roth, Guillaume Gauron, Marcus Baumann
Continuous Flow Approach for Benzylic Photo-oxidations Using Compressed Air. Organic process research & development 28 (8) (2024)

volume 28, number 1, 2023

Mukut Gohain, Modibo S Malefo, Phaladi Kunyane, Chantal Scholtz, Sangeeta Baruah, Andile Zitha, Gerrit van der Klashorst, Hannes Malan
Process Development for the Manufacture of the Antimalarial Amodiaquine Dihydrochloride Dihydrate. Organic process research & development 28 (1) (2023)
Mukut Gohain, Modibo S Malefo, Phaladi Kunyane, Chantal Scholtz, Sangeeta Baruah, Andile Zitha, Gerrit van der Klashorst, Hannes Malan
Process Development for the Manufacture of the Antimalarial Amodiaquine Dihydrochloride Dihydrate. Organic process research & development 28 (1) (2023)
Pankaj V Khairnar, Sarah L Bliese, Ravi Kumar Ongolu, Li-Mei Jin, Michael G Laidlaw, Kai O Donsbach, B Frank Gupton, Ryan C Nelson, Charles S Shanahan
Highly Regioselective Protecting-Group-Free Synthesis of the Antimalarial Drug MMV693183. Organic process research & development 28 (1) (2023)
Mukut Gohain, Modibo S Malefo, Phaladi Kunyane, Chantal Scholtz, Sangeeta Baruah, Andile Zitha, Gerrit van der Klashorst, Hannes Malan
Process Development for the Manufacture of the Antimalarial Amodiaquine Dihydrochloride Dihydrate. Organic process research & development 28 (1) (2023)
Pankaj V Khairnar, Sarah L Bliese, Ravi Kumar Ongolu, Li-Mei Jin, Michael G Laidlaw, Kai O Donsbach, B Frank Gupton, Ryan C Nelson, Charles S Shanahan
Highly Regioselective Protecting-Group-Free Synthesis of the Antimalarial Drug MMV693183. Organic process research & development 28 (1) (2023)

volume 28, number 5, 2023

Katia Martina, Maria Jesus Moran, Maela Manzoli, Mikhail V Trukhan, Simon Kuhn, Tom Van Gerven, Giancarlo Cravotto
Copper-Catalyzed Continuous-Flow Transfer Hydrogenation of Nitroarenes to Anilines: A Scalable and Reliable Protocol. Organic process research & development 28 (5) (2023)
Arlene Bonner, Marcus Baumann
Development of a Continuous Flow Baldwin Rearrangement Process and Its Comparison to Traditional Batch Mode. Organic process research & development 28 (5) (2023)
Arlene Bonner, Marcus Baumann
Development of a Continuous Flow Baldwin Rearrangement Process and Its Comparison to Traditional Batch Mode. Organic process research & development 28 (5) (2023)
Parth Naik, Jorge García-Lacuna, Patrick O'Neill, Marcus Baumann
Continuous Flow Oxidation of Alcohols Using TEMPO/NaOCl for the Selective and Scalable Synthesis of Aldehydes. Organic process research & development 28 (5) (2023)
Katia Martina, Maria Jesus Moran, Maela Manzoli, Mikhail V Trukhan, Simon Kuhn, Tom Van Gerven, Giancarlo Cravotto
Copper-Catalyzed Continuous-Flow Transfer Hydrogenation of Nitroarenes to Anilines: A Scalable and Reliable Protocol. Organic process research & development 28 (5) (2023)
Parth Naik, Jorge García-Lacuna, Patrick O'Neill, Marcus Baumann
Continuous Flow Oxidation of Alcohols Using TEMPO/NaOCl for the Selective and Scalable Synthesis of Aldehydes. Organic process research & development 28 (5) (2023)

volume 27, number 6, 2023

Jingyu Wang, Elif Erdem, John M Woodley
Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas-Liquid Interface. Organic process research & development 27 (6) (2023)
Desiree M Dalligos, Michael J Pilling, Georgios Dimitrakis, Liam T Ball
Coaxial Dielectric Spectroscopy as an In-Line Process Analytical Technique for Reaction Monitoring. Organic process research & development 27 (6) (2023)

volume 27, number 7, 2023

Thomas Hilberath, Remco van Oosten, Juliet Victoria, Hugo Brasselet, Miguel Alcalde, John M Woodley, Frank Hollmann
Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane. Organic process research & development 27 (7) (2023)
Matisyahu S Fogel, Kazunori Koide
Recent Progress on One-Pot Multisubstrate Screening. Organic process research & development 27 (7) (2023)
Reilly E Sonstrom, Zoua Pa Vang, Haley N Scolati, Justin L Neill, Brooks H Pate, Joseph R Clark
Rapid Enantiomeric Excess Measurements of Enantioisotopomers by Molecular Rotational Resonance Spectroscopy. Organic process research & development 27 (7) (2023)
Flavio S P Cardoso, Appasaheb L Kadam, Ryan C Nelson, John W Tomlin, Dipendra Dahal, Christopher S Kuehner, Gard Gudvangen, Anthony J Arduengo, Justina M Burns, Sarah L Bliese, David R Snead, Fengrui Qu, Ken Belmore, Saeed Ahmad, Toolika Agrawal, Joshua D Sieber, Kai Oliver Donsbach
Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223. Organic process research & development 27 (7) (2023)

volume 27, number 9, 2023

Tobias Lucas, Jule-Philipp Dietz, Flavio S P Cardoso, David R Snead, Ryan C Nelson, Kai Oliver Donsbach, B Frank Gupton, Jason Sirleaf
Short and Efficient Synthesis of the Antituberculosis Agent Pretomanid from ( R )-Glycidol. Organic process research & development 27 (9) (2023)
William Eales, Chris J Price, William Hicks, Paul A Mulheran
Properties of Packed Bed Structures Formed during Filtration: A Two and Three-Dimensional Model. Organic process research & development 27 (9) (2023)