Anthony R Fehr

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 44

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Microbiology spectrum

Pathogens (Basel, Switzerland)

University of Kansas

Washington University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kansas Aug 18 2018

United States

Assistant Professor :: Molecular Biosciences

Education History

Washington University

United States

PHD :: Molecular Microbiology and Microbial Pathogenesis

Publications

Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Anuradha Roy, Joseph J O'Connor, Roshan Ghimire, Reem Khattabi, Rakshya Shrestha, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Rudragouda Channappanavar, Anthony R Fehr
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Srivatsan Parthasarathy, Pradtahna Saenjamsai, Hongping Hao, Anna Ferkul, Jessica J Pfannenstiel, Ellen L Suder, Daniel S Bejan, Yating Chen, Nancy Schwarting, Masanori Aikawa, Elke Muhlberger, Robin C Orozco, Christopher S Sullivan, Michael S Cohen, David J Davido, Adam J Hume, Anthony R Fehr
PARP14 is pro- and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses. bioRxiv : the preprint server for biology (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Anuradha Roy, Joseph J O'Connor, Roshan Ghimire, Reem Khattabi, Rakshya Shrestha, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Rudragouda Channappanavar, Anthony R Fehr
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Anuradha Roy, Joseph J O'Connor, Roshan Ghimire, Reem Khattabi, Rakshya Shrestha, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Rudragouda Channappanavar, Anthony R Fehr
Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Joseph J O'Connor, Roshan Ghimire, Rakshya Shrestha, Reem Khattabi, Pradtahna Saenjamsai, Srivatsan Parthasarathy, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Anuradha Roy, Rudragouda Channappanavar, Anthony R Fehr
Mutation of a highly conserved isoleucine residue in loop 2 of several 𝛽-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Joseph J O'Connor, Roshan Ghimire, Rakshya Shrestha, Reem Khattabi, Pradtahna Saenjamsai, Srivatsan Parthasarathy, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Anuradha Roy, Rudragouda Channappanavar, Anthony R Fehr
Mutation of a highly conserved isoleucine residue in loop 2 of several 𝛽-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Srivatsan Parthasarathy, Pradtahna Saenjamsai, Hongping Hao, Anna Ferkul, Jessica J Pfannenstiel, Ellen L Suder, Daniel S Bejan, Yating Chen, Nancy Schwarting, Masanori Aikawa, Elke Muhlberger, Robin C Orozco, Christopher S Sullivan, Michael S Cohen, David J Davido, Adam J Hume, Anthony R Fehr
PARP14 is pro- and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses. bioRxiv : the preprint server for biology (2024)
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M O Alhammad, Joseph J O'Connor, Roshan Ghimire, Rakshya Shrestha, Reem Khattabi, Pradtahna Saenjamsai, Srivatsan Parthasarathy, Peter R McDonald, Philip Gao, David K Johnson, Sunil S More, Anuradha Roy, Rudragouda Channappanavar, Anthony R Fehr
Mutation of a highly conserved isoleucine residue in loop 2 of several β -coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection. bioRxiv : the preprint server for biology (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Srivatsan Parthasarathy, Pradtahna Saenjamsai, Hongping Hao, Anna Ferkul, Jessica J Pfannenstiel, Ellen L Suder, Daniel S Bejan, Yating Chen, Nancy Schwarting, Masanori Aikawa, Elke Muhlberger, Robin C Orozco, Christopher S Sullivan, Michael S Cohen, David J Davido, Adam J Hume, Anthony R Fehr
PARP14 is pro- and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses. bioRxiv : the preprint server for biology (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Clayton J Otter, Nicole Bracci, Nicholas A Parenti, Chengjin Ye, Abhishek Asthana, Ebba K Blomqvist, Li Hui Tan, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, James M Burke, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Srivatsan Parthasarathy, Pradtahna Saenjamsai, Hongping Hao, Anna Ferkul, Jessica J Pfannenstiel, Ellen L Suder, Daniel S Bejan, Yating Chen, Nancy Schwarting, Masanori Aikawa, Elke Muhlberger, Robin C Orozco, Christopher S Sullivan, Michael S Cohen, David J Davido, Adam J Hume, Anthony R Fehr
PARP14 is pro- and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses. bioRxiv : the preprint server for biology (2024)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Yousef M O Alhammad, Srivatsan Parthasarathy, Roshan Ghimire, Joseph J O'Connor, Catherine M Kerr, Jessica J Pfannenstiel, Debarati Chanda, Caden A Miller, Robert L Unckless, Sonia Zuniga, Luis Enjuanes, Sunil S More, Rudragouda Channappanavar, Anthony R Fehr
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice. bioRxiv : the preprint server for biology (2023)
Joseph J O'Connor, Dana V Ferraris, Anthony R Fehr
An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors. Pathogens (Basel, Switzerland) 12 (10) (2023)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Joseph J O'Connor, Lynden Voth, Jeremiah Athmer, Nicholas M George, Christopher M Connelly, Anthony R Fehr
Two Commercially Available Blood-Stabilization Reagents Serve as Potent Inactivators of Coronaviruses. Pathogens (Basel, Switzerland) 12 (9) (2023)
Yousef M Alhammad, Srivatsan Parthasarathy, Roshan Ghimire, Catherine M Kerr, Joseph J O'Connor, Jessica J Pfannenstiel, Debarati Chanda, Caden A Miller, Nathalie Baumlin, Matthias A Salathe, Robert L Unckless, Sonia Zuñiga, Luis Enjuanes, Sunil More, Rudragouda Channappanavar, Anthony R Fehr
SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Proceedings of the National Academy of Sciences of the United States of America 120 (35) (2023)
Catherine M Kerr, Srivatsan Parthasarathy, Nancy Schwarting, Joseph J O'Connor, Emily Giri, Sunil More, Robin C Orozco, Anthony R Fehr
PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner. bioRxiv : the preprint server for biology (2023)
Catherine M Kerr, Srivatsan Parthasarathy, Nancy Schwarting, Joseph J O'Connor, Jessica J Pfannenstiel, Emily Giri, Sunil More, Robin C Orozco, Anthony R Fehr
PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell- and tissue-specific manner. Journal of virology (2023)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Clayton J Otter, Nicole R Bracci, Nicholas A Parenti, Chengjin Ye, Li Hui Tan, Abhishek Asthana, Jessica J Pfannenstiel, Nathaniel Jackson, Anthony R Fehr, Robert H Silverman, Noam A Cohen, Luis Martinez-Sobrido, Susan R Weiss
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling. bioRxiv : the preprint server for biology (2023)
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff, Sven T Sowa, Albert Galera-Prat, Dana V Ferraris, Mirko M Maksimainen, Anthony R Fehr, Juha P Heiskanen, Lari Lehtiö
Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv : the preprint server for biology (2023)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum 11 (1) (2022)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum (2022)
Anthony K L Leung, Diane E Griffin, Jürgen Bosch, Anthony R Fehr
The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses. Pathogens (Basel, Switzerland) 11 (1) (2022)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum (2022)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum 11 (1) (2022)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum 11 (1) (2022)
Courtney E Comar, Clayton J Otter, Jessica Pfannenstiel, Ethan Doerger, David M Renner, Li Hui Tan, Stanley Perlman, Noam A Cohen, Anthony R Fehr, Susan R Weiss
MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 119 (21) (2022)
Srivatsan Parthasarathy, Anthony R Fehr
PARP14: A key ADP-ribosylating protein in host-virus interactions? PLoS pathogens 18 (6) (2022)
Cindy Y Ly, Jessica Pfannenstiel, Anil Pant, Zhilong Yang, Anthony R Fehr, Maxim S Rodzkin, David J Davido
Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles. Microbiology spectrum 11 (1) (2022)
Anu Roy, Yousef M O Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo, Sarah Wazir, Dana V Ferraris, Lari Lehtiö, Anthony K L Leung, Anthony R Fehr
Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening. bioRxiv : the preprint server for biology (2022)
Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald, Philip Gao, Louis Nonfoux, Kevin P Battaile, David K Johnson, Erik D Holmstrom, Guy G Poirier, Scott Lovell, Anthony R Fehr
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. Journal of virology 95 (3) (2021)
Lynden S Voth, Joseph J O'Connor, Catherine M Kerr, Ethan Doerger, Nancy Schwarting, Parker Sperstad, David K Johnson, Anthony R Fehr
An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus replication. bioRxiv : the preprint server for biology (2021)
Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald, Philip Gao, Louis Nonfoux, Kevin P Battaile, David K Johnson, Erik D Holmstrom, Guy G Poirier, Scott Lovell, Anthony R Fehr
The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase. bioRxiv : the preprint server for biology (2020)
Yousef M O Alhammad, Anthony R Fehr
The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation. Viruses 12 (4) (2020)
Matthew E Grunewald, Yating Chen, Chad V Kuny, Takashi Maejima, Robert Lease, Dana Ferraris, Masanori Aikawa, Christopher S Sullivan, Stanley Perlman, Anthony R Fehr
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression. PLoS pathogens 15 (5) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Anthony R Fehr