Brian D Sykes

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 11

Top Topics

Amyotrophic Lateral Sclerosis

Skeletal Muscle

Capillary Electrophoresis

Perovskite Solar Cells

Top Venues

ACS chemical biology

Journal of biomolecular NMR

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Fangze Cai, Thomas Kampourakis, Priyanka Parijat, Kieran T Cockburn, Brian D Sykes
Conversion of a Cardiac Muscle Modulator from an Inhibitor to an Activator. ACS medicinal chemistry letters 14 (4) (2023)
Fangze Cai, Thomas Kampourakis, Kieran T Cockburn, Brian D Sykes
Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7. ACS chemical biology 17 (6) (2022)
Fangze Cai, Thomas Kampourakis, Brittney A Klein, Brian D Sykes
A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction. ACS medicinal chemistry letters 12 (9) (2021)
Monica X Li, Pascal Mercier, James J Hartman, Brian D Sykes
Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle. Journal of medicinal chemistry 64 (6) (2021)
Ze-Lin Fu, Pascal Mercier, Ghazaleh Eskandari-Sedighi, Jing Yang, David Westaway, Brian D Sykes
Metabolomic study of disease progression in scrapie prion infected mice; validation of a novel method for brain metabolite extraction. Metabolomics : Official journal of the Metabolomic Society 16 (6) (2020)
Ian M Robertson, Brittney A Klein, Brian D Sykes
Optimizing fluorine labelling for 19F solid-state NMR in oriented biological systems. Journal of biomolecular NMR 74 (1) (2020)
Fangze Cai, Ian M Robertson, Thomas Kampourakis, Brittney A Klein, Brian D Sykes
The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers. ACS chemical biology 15 (8) (2020)
Brittney A Klein, Brian D Sykes
Feasibility of trifluoromethyl TROSY NMR at high magnetic fields. Journal of biomolecular NMR 73 (10-11) (2019)
Robert C C Mercer, Nathalie Daude, Lyudmyla Dorosh, Ze-Lin Fu, Charles E Mays, Hristina Gapeshina, Serene L Wohlgemuth, Claudia Y Acevedo-Morantes, Jing Yang, Neil R Cashman, Michael B Coulthart, Dawn M Pearson, Jeffrey T Joseph, Holger Wille, Jiri G Safar, Gerard H Jansen, Maria Stepanova, Brian D Sykes, David Westaway
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles. PLoS pathogens 14 (1) (2018)
Brittney A Klein, Béla Reiz, Ian M Robertson, Malcolm Irving, Liang Li, Yin-Biao Sun, Brian D Sykes
Reversible Covalent Reaction of Levosimendan with Cardiac Troponin C in Vitro and in Situ. Biochemistry 57 (15) (2018)
Fangze Cai, Peter M Hwang, Brian D Sykes
Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin. Biochemistry 57 (46) (2018)