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Brian W Bigger (Brian Bigger, B W Bigger)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 13

Top Venues

PloS one

EMBO molecular medicine

International journal of molecular sciences

Pharmaceutics

University of Manchester

Imperial College London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Manchester

United Kingdom

Reader

Education History

Imperial College London

United Kingdom

PHD

Publications

Anna-Maria Wiesinger, Brian W Bigger, Roberto Giugliani, Christina Lampe, Maurizio Scarpa, Tobias Moser, Christoph Kampmann, Georg Zimmermann, Florian B Lagler
RETRACTED: Wiesinger et al. An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis. Pharmaceutics 2023, 15 , 1565. Pharmaceutics 15 (11) (2023)
Anna-Maria Wiesinger, Brian W Bigger, Roberto Giugliani, Christina Lampe, Maurizio Scarpa, Tobias Moser, Christoph Kampmann, Georg Zimmermann, Florian B Lagler
An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis. Pharmaceutics 15 (5) (2023)
Oriana Mandolfo, Helen Parker, Brian W Bigger
Innate Immunity in Mucopolysaccharide Diseases. International journal of molecular sciences 23 (4) (2022)
Claire Horgan, Simon A Jones, Brian W Bigger, Robert Wynn
Current and Future Treatment of Mucopolysaccharidosis (MPS) Type II: Is Brain-Targeted Stem Cell Gene Therapy the Solution for This Devastating Disorder? International journal of molecular sciences 23 (9) (2022)
Arunabha Ghosh, Stewart Rust, Kia Langford-Smith, Daniel Weisberg, Maria Canal, Catherine Breen, Michelle Hepburn, Karen Tylee, Frédéric M Vaz, Andy Vail, Frits Wijburg, Claire O'Leary, Helen Parker, J Ed Wraith, Brian W Bigger, Simon A Jones
High dose genistein in Sanfilippo syndrome: A randomised controlled trial. Journal of inherited metabolic disease 44 (5) (2021)
Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao, Jalal Asadi, Emily Glover, Arunabha Ghosh, Simon Jones, Fiona L Wilkinson, David Brough, Emmanuel Pinteaux, Hervé Boutin, Brian W Bigger
Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA. EMBO molecular medicine 12 (3) (2020)
Hélène F E Gleitz, Ai Yin Liao, James R Cook, Samuel F Rowlston, Gabriella Ma Forte, Zelpha D'Souza, Claire O'Leary, Rebecca J Holley, Brian W Bigger
Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms. EMBO molecular medicine 10 (7) (2019)
K Yu, A S Youshani, F L Wilkinson, C O'Leary, P Cook, L Laaniste, A Liao, D Mosses, C Waugh, H Shorrock, O Pathmanaban, A Macdonald, I Kamaly-Asl, F Roncaroli, Brian W Bigger
A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma. Neuropathology and applied neurobiology 45 (2) (2018)
Abhijit Ricky Pal, Jean Mercer, Simon A Jones, Iain A Bruce, Brian W Bigger
Substrate accumulation and extracellular matrix remodelling promote persistent upper airway disease in mucopolysaccharidosis patients on enzyme replacement therapy. PloS one 13 (9) (2018)
Rebecca J Holley, Shaun R Wood, Brian W Bigger
Delivering Hematopoietic Stem Cell Gene Therapy Treatments for Neurological Lysosomal Diseases. ACS chemical neuroscience 10 (1) (2018)
Helen Parker, Brian W Bigger
The role of innate immunity in mucopolysaccharide diseases. Journal of neurochemistry 148 (5) (2018)
Kenny Kwok-Hei Yu, Jessica T Taylor, Omar N Pathmanaban, Amir Saam Youshani, Deniz Beyit, Joanna Dutko-Gwozdz, Roderick Benson, Gareth Griffiths, Ian Peers, Peter Cueppens, Brian A Telfer, Kaye J Williams, Catherine McBain, Ian D Kamaly-Asl, Brian W Bigger
High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma. PloS one 13 (3) (2018)
Hélène F E Gleitz, Claire O'Leary, Rebecca J Holley, Brian W Bigger
Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II. PloS one 12 (2) (2017)

Brian W Bigger.css-eqlu8i{font-size:small;padding-left:4px;} (Brian Bigger, B W Bigger)

Publication Activity (10 Years)

Top Topics

Top Venues

Brian W Bigger (Brian Bigger, B W Bigger)