C James Chou (James C Chou)

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 9

Top Topics

Histone Deacetylase

Top Venues

Journal of medicinal chemistry

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Kairui Yue, Simin Sun, Geng Jia, Mengting Qin, Xiaohan Hou, C James Chou, Chao Huang, Xiaoyang Li
First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation. Journal of medicinal chemistry 65 (18) (2022)
Feng He, C James Chou, Matthias Scheiner, Eleonora Poeta, Natalia Yuan Chen, Sandra Gunesch, Matthias Hoffmann, Christoph Sotriffer, Barbara Monti, Tangui Maurice, Michael Decker
Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer's Disease Mouse Model. Journal of medicinal chemistry 64 (7) (2021)
Yuqi Jiang, Jie Xu, Kairui Yue, Chao Huang, Mengting Qin, Dongyu Chi, Qixin Yu, Yue Zhu, Xiaohan Hou, Tongqiang Xu, Min Li, C James Chou, Xiaoyang Li
Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo. Journal of medicinal chemistry 65 (1) (2021)
Xiaoyang Li, Richard A Himes, Lyndsey C Prosser, Charleston F Christie, Emma Watt, Sharon F Edwards, Cameron S Metcalf, Peter J West, Karen S Wilcox, Sherine S L Chan, C James Chou
Discovery of the First Vitamin K Analogue as a Potential Treatment of Pharmacoresistant Seizures. Journal of medicinal chemistry 63 (11) (2020)
Jia Jia, Eun Je Jeon, Mei Li, Dylan J Richards, Youngmee Jung, Ryan W Barrs, Robert Coyle, Xiaoyang Li, C James Chou, Michael J Yost, Sharon Gerecht, Seung-Woo Cho, Ying Mei
Evolutionarily conserved sequence motif analysis guides development of chemically defined hydrogels for therapeutic vascularization. Science advances 6 (28) (2020)
Xiaoyang Li, Yuqi Jiang, Yuri K Peterson, Tongqiang Xu, Richard A Himes, Xin Luo, Guilin Yin, Elizabeth S Inks, Nathan Dolloff, Stephanie Halene, Sherine S L Chan, C James Chou
Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity. Journal of medicinal chemistry 63 (10) (2020)
Xuewu Liang, Jie Zang, Xiaoyang Li, Shuai Tang, Min Huang, Meiyu Geng, C James Chou, Chunpu Li, Yichun Cao, Wenfang Xu, Hong Liu, Yingjie Zhang
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies. Journal of medicinal chemistry 62 (8) (2019)
Jie Zang, Xuewu Liang, Yongxue Huang, Yuping Jia, Xiaoyang Li, Wenfang Xu, C James Chou, Yingjie Zhang
Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously. Journal of medicinal chemistry 61 (12) (2018)
Xiaoyang Li, Yuri K Peterson, Elizabeth S Inks, Richard A Himes, Jiaying Li, Yingjie Zhang, Xiujie Kong, C James Chou
Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status. Journal of medicinal chemistry 61 (6) (2018)