Charles A Brearley

Scopus Author ID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 25

Top Topics

Liquid Chromatography

Tyrosine Kinase

Fluorescent Probe

Top Venues

Nature communications

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Colleen Sprigg, Philip Thomas Leftwich, Emily Burton, Dawn Scholey, Michael R Bedford, Charles A Brearley
Accentuating the positive and eliminating the negative: Efficacy of TiO2 as digestibility index marker for poultry nutrition studies. PloS one 18 (6) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Colleen Sprigg, Philip Thomas Leftwich, Emily Burton, Dawn Scholey, Michael R Bedford, Charles A Brearley
Accentuating the positive and eliminating the negative: Efficacy of TiO2 as digestibility index marker for poultry nutrition studies. PloS one 18 (6) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Colleen Sprigg, Philip Thomas Leftwich, Emily Burton, Dawn Scholey, Michael R Bedford, Charles A Brearley
Accentuating the positive and eliminating the negative: Efficacy of TiO2 as digestibility index marker for poultry nutrition studies. PloS one 18 (6) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Colleen Sprigg, Philip Thomas Leftwich, Emily Burton, Dawn Scholey, Michael R Bedford, Charles A Brearley
Accentuating the positive and eliminating the negative: Efficacy of TiO2 as digestibility index marker for poultry nutrition studies. PloS one 18 (6) (2023)
Gregory D Rix, Colleen Sprigg, Hayley Whitfield, Andrew M Hemmings, Jonathan D Todd, Charles A Brearley
Characterisation of a soil MINPP phytase with remarkable long-term stability and activity from Acinetobacter sp. PloS one 17 (8) (2022)
Isabella Maria Acquistapace, Emma J Thompson, Imke Kühn, Michael R Bedford, Charles A Brearley, Andrew M Hemmings
Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA. International journal of molecular sciences 23 (11) (2022)
Colleen Sprigg, Hayley Whitfield, Emily Burton, Dawn Scholey, Michael R Bedford, Charles A Brearley
Phytase dose-dependent response of kidney inositol phosphate levels in poultry. PloS one 17 (10) (2022)
Hayley Whitfield, Andrew M Hemmings, Stephen J Mills, Kendall Baker, Gaye White, Stuart Rushworth, Andrew M Riley, Barry V L Potter, Charles A Brearley
Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention. Journal of medicinal chemistry 64 (7) (2021)
Gregory D Rix, Jonathan D Todd, Andrew L Neal, Charles A Brearley
Improved sensitivity, accuracy and prediction provided by a high-performance liquid chromatography screen for the isolation of phytase-harbouring organisms from environmental samples. Microbial biotechnology 14 (4) (2020)
Isabella Maria Acquistapace, Monika Ziętek, Arthur W H Li, Melissa Salmon, Imke Kühn, Mike R Bedford, Charles A Brearley, Andrew M Hemmings
Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced fit structural mechanism. The Journal of biological chemistry (2020)
Megan L Shipton, Andrew M Riley, Ana M Rossi, Charles A Brearley, Colin W Taylor, Barry V L Potter
Both d- and l-Glucose Polyphosphates Mimic d-myo-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins(1,4,5)P3 Receptor. Journal of medicinal chemistry 63 (10) (2020)
Beth T Williams, Kasha Cowles, Ana Bermejo Martínez, Andrew R J Curson, Yanfen Zheng, Jingli Liu, Simone Newton-Payne, Andrew J Hind, Chun-Yang Li, Peter Paolo L Rivera, Ornella Carrión, Ji Liu, Lewis G Spurgin, Charles A Brearley, Brett Wagner Mackenzie, Benjamin J Pinchbeck, Ming Peng, Jennifer Pratscher, Xiao-Hua Zhang, Yu-Zhong Zhang, J Colin Murrell, Jonathan D Todd
Bacteria are important dimethylsulfoniopropionate producers in coastal sediments. Nature microbiology 4 (11) (2019)
Hayley Whitfield, Megan Gilmartin, Kendall Baker, Andrew M Riley, H Y Godage, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase. Journal of medicinal chemistry 61 (19) (2018)