Barry V L Potter

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Topics

Molecular Docking

Postmenopausal Women

Crystal Structure

Top Venues

Molecules (Basel, Switzerland)

Journal of medicinal chemistry

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Shane W Garrett, Megan L Shipton, Charles A Brearley, Barry V L Potter, Beatriz González
Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. Nature communications 15 (1) (2024)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Ylana Adami Franco, Manoel Oliveira de Moraes Junior, Larissa A C Carvalho, Wolfgang Dohle, Renaira Oliveira da Silva, Isabella Harumi Yonehara Noma, Keli Lima, Barry V L Potter, João Agostinho Machado-Neto, Silvya Stuchi Maria-Engler
2-Methoxyestradiol-3,17- O , O -bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells. International journal of molecular sciences 24 (14) (2023)
Megan L Shipton, Fathima A Jamion, Simon Wheeler, Andrew M Riley, Felix Plasser, Barry V L Potter, Stephen J Butler
Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP 5 . Chemical science 14 (19) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Mariana Sacerdoti, Lissy Z F Gross, Andrew M Riley, Karin Zehnder, Abhijeet Ghode, Sebastián Klinke, Ganesh Srinivasan Anand, Kristina A Paris, Angelika Winkel, Amanda Katherina Herbrand, H Yasmin Godage, Gyles E Cozier, Evelyn Süß, Jörg O Schulze, Daniel Pastor-Flores, Mariela Bollini, María Victoria Cappellari, Dmitri I Svergun, Melissa Ann Graewert, Pedro F Aramendia, Alejandro E Leroux, Barry V L Potter, Carlos Jaime Camacho, Ricardo M Biondi
Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein. Science signaling 16 (789) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Megan L Shipton, Fathima A Jamion, Simon Wheeler, Andrew M Riley, Felix Plasser, Barry V L Potter, Stephen J Butler
Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP 5 . Chemical science 14 (19) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Ruqaiyyah Siddiqui, Mutasem Rawas-Qalaji, Mohammed I El-Gamal, Sreedevi Sajeev, Jayalakshmi Jagal, Seyed-Omar Zaraei, Rawan M Sbenati, Hanan S Anbar, Wolfgang Dohle, Barry V L Potter, Naveed Ahmad Khan
Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations. Antibiotics (Basel, Switzerland) 12 (3) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Megan L Shipton, Fathima A Jamion, Simon Wheeler, Andrew M Riley, Felix Plasser, Barry V L Potter, Stephen J Butler
Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP 5 . Chemical science 14 (19) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Ruqaiyyah Siddiqui, Mutasem Rawas-Qalaji, Mohammed I El-Gamal, Sreedevi Sajeev, Jayalakshmi Jagal, Seyed-Omar Zaraei, Rawan M Sbenati, Hanan S Anbar, Wolfgang Dohle, Barry V L Potter, Naveed Ahmad Khan
Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations. Antibiotics (Basel, Switzerland) 12 (3) (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry (2023)
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1). Biochemistry 63 (1) (2023)
Wolfgang Dohle, Xiangdong Su, Yamni Nigam, Edward Dudley, Barry V L Potter
Synthesis and In Vitro Antimicrobial SAR of Benzyl and Phenyl Guanidine and Aminoguanidine Hydrazone Derivatives. Molecules (Basel, Switzerland) 28 (1) (2022)
Scott D Hargrave, Annie Margaretha Joubert, Barry V L Potter, Wolfgang Dohle, Sumari Marais, Anne Elisabeth Mercier
Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451. Molecules (Basel, Switzerland) 27 (12) (2022)
Wolfgang Dohle, Xiangdong Su, Yamni Nigam, Edward Dudley, Barry V L Potter
Synthesis and In Vitro Antimicrobial SAR of Benzyl and Phenyl Guanidine and Aminoguanidine Hydrazone Derivatives. Molecules (Basel, Switzerland) 28 (1) (2022)
Wolfgang Dohle, Hannah Asiki, Wojciech Gruchot, Paul A Foster, Havreen K Sahota, Ruoli Bai, Kirsten E Christensen, Ernest Hamel, Barry V L Potter
2-Difluoromethoxy-Substituted Estratriene Sulfamates: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Steroid Sulfatase Inhibition. ChemMedChem (2022)
Wolfgang Dohle, Xiangdong Su, Yamni Nigam, Edward Dudley, Barry V L Potter
Synthesis and In Vitro Antimicrobial SAR of Benzyl and Phenyl Guanidine and Aminoguanidine Hydrazone Derivatives. Molecules (Basel, Switzerland) 28 (1) (2022)
Huanchen Wang, Lalith Perera, Nikolaus Jork, Guangning Zong, Andrew M Riley, Barry V L Potter, Henning J Jessen, Stephen B Shears
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop. Nature communications 13 (1) (2022)
María Ángeles Márquez-Moñino, Raquel Ortega-García, Megan L Shipton, Elsa Franco Echevarria, Andrew M Riley, Julia Sanz-Aparicio, Barry V L Potter, Beatriz González
Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping. Science advances 7 (17) (2021)
Joanna M Watt, Richard Graeff, Barry V L Potter
Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-inosine 5'-monophosphate, Analogues and Early Structure-Activity Relationship. Molecules (Basel, Switzerland) 26 (23) (2021)
Hayley Whitfield, Andrew M Hemmings, Stephen J Mills, Kendall Baker, Gaye White, Stuart Rushworth, Andrew M Riley, Barry V L Potter, Charles A Brearley
Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention. Journal of medicinal chemistry 64 (7) (2021)
Nigel Vicker, Helen V Bailey, Joanna M Day, Mary F Mahon, Andrew Smith, Helena J Tutill, Atul Purohit, Barry V L Potter
Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3. Molecules (Basel, Switzerland) 26 (23) (2021)
Stephen J Mills, Ana M Rossi, Vera Konieczny, Daniel Bakowski, Colin W Taylor, Barry V L Potter
d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities. Journal of medicinal chemistry 63 (6) (2020)
Alfred C Chin, Zhe Gao, Andrew M Riley, David Furkert, Christopher Wittwer, Amit Dutta, Tomas Rojas, Evan R Semenza, Robin A Felder, Jennifer L Pluznick, Henning Jacob Jessen, Dorothea Fiedler, Barry V L Potter, Solomon H Snyder, Chenglai Fu
The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α. Science advances 6 (44) (2020)
Marco Mottinelli, Maša Sinreih, Tea Lanišnik Rižner, Mathew P Leese, Barry V L Potter
N-Phenyl-1,2,3,4-tetrahydroisoquinoline: An Alternative Scaffold for the Design of 17β-Hydroxysteroid Dehydrogenase 1 Inhibitors. ChemMedChem 16 (1) (2020)
Megan L Shipton, Andrew M Riley, Ana M Rossi, Charles A Brearley, Colin W Taylor, Barry V L Potter
Both d- and l-Glucose Polyphosphates Mimic d-myo-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins(1,4,5)P3 Receptor. Journal of medicinal chemistry 63 (10) (2020)
Helen V Bailey, Mary F Mahon, Nigel Vicker, Barry V L Potter
Rapid and Efficient Microwave-Assisted Friedländer Quinoline Synthesis. ChemistryOpen 9 (11) (2020)
Ondřej Baszczyňski, Joanna M Watt, Monika D Rozewitz, Andreas H Guse, Ralf Fliegert, Barry V L Potter
Synthesis of Terminal Ribose Analogues of Adenosine 5'-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2. The Journal of organic chemistry 84 (10) (2019)
Jacob T Andring, Wolfgang Dohle, Chingkuang Tu, Barry V L Potter, Robert McKenna
3,17β-Bis-sulfamoyloxy-2-methoxyestra-1,3,5(10)-triene and Nonsteroidal Sulfamate Derivatives Inhibit Carbonic Anhydrase IX: Structure-Activity Optimization for Isoform Selectivity. Journal of medicinal chemistry 62 (4) (2019)
Andrew M Riley, Huanchen Wang, Stephen B Shears, Barry V L Potter
Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7. MedChemComm 10 (7) (2019)
Joanna M Watt, Mark P Thomas, Barry V L Potter
Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers. Scientific reports 8 (1) (2018)
Bo Zhang, Joanna M Watt, Chiara Cordiglieri, Werner Dammermann, Mary F Mahon, Alexander Flügel, Andreas H Guse, Barry V L Potter
Small Molecule Antagonists of NAADP-Induced Ca2+ Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease. Scientific reports 8 (1) (2018)
Wolfgang Dohle, Fabrice L Jourdan, Grégory Menchon, Andrea E Prota, Paul A Foster, Pascoe Mannion, Ernest Hamel, Mark P Thomas, Philip G Kasprzyk, Eric Ferrandis, Michel O Steinmetz, Mathew P Leese, Barry V L Potter
Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure. Journal of medicinal chemistry 61 (3) (2018)
Hayley Whitfield, Megan Gilmartin, Kendall Baker, Andrew M Riley, H Y Godage, Barry V L Potter, Andrew M Hemmings, Charles A Brearley
A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase. Journal of medicinal chemistry 61 (19) (2018)
Ralf Fliegert, Andreas Bauche, Adriana-Michelle Wolf Pérez, Joanna M Watt, Monika D Rozewitz, Riekje Winzer, Mareike Janus, Feng Gu, Annette Rosche, Angelika Harneit, Marianne Flato, Christelle Moreau, Tanja Kirchberger, Valerie Wolters, Barry V L Potter, Andreas H Guse
2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist. Nature chemical biology 13 (9) (2017)
Mark P Thomas, Christophe Erneux, Barry V L Potter
SHIP2: Structure, Function and Inhibition. Chembiochem : a European journal of chemical biology 18 (3) (2017)
Marco Mottinelli, Mathew P Leese, Barry V L Potter
Accessing simply-substituted 4-hydroxytetrahydroisoquinolines via Pomeranz-Fritsch-Bobbitt reaction with non-activated and moderately-activated systems. Beilstein journal of organic chemistry 13 (2017)
Joanna M Watt, Richard Graeff, Mark P Thomas, Barry V L Potter
Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid "L-cyclic inosine 5'-diphosphate ribose". Scientific reports 7 (1) (2017)