Charles R Dean (C R Dean)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2022
Publications (10 Years): 12

Top Venues

Antimicrobial agents and chemotherapy

mSphere

ACS infectious diseases

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Johanne Blais, Charles R Dean, Guillaume Lapointe, Jennifer A Leeds, Sylvia Ma, Laura Morris, Heinz E Moser, Colin S Osborne, Katherine R Prosen, Daryl Richie, Colin Skepper, Katherine Thompson, Jason Vo, Qin Yue, Alexey Rivkin
In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor. Antimicrobial agents and chemotherapy (2022)
Srijan Ranjitkar, Adriana K Jones, Mina Mostafavi, Zachary Zwirko, Oleg Iartchouk, S Whitney Barnes, John R Walker, Thomas W Willis, Patrick S Lee, Charles R Dean
Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of β-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression. Antimicrobial agents and chemotherapy 63 (2) (2019)
Srijan Ranjitkar, Folkert Reck, Xiaobo Ke, Qingming Zhu, Glenn McEnroe, Sara L Lopez, Charles R Dean
Identification of Mutations in the mrdA Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of Escherichia coli Clinical Isolates with Mutations in ftsI (PBP3) and Which Carry bla NDM-1. mSphere 4 (4) (2019)
Folkert Reck, Alun Bermingham, Johanne Blais, Anthony Casarez, Richard Colvin, Charles R Dean, Markus Furegati, Luis Gamboa, Ellena Growcott, Cindy Li, Sara Lopez, Louis Metzger, Sandro Nocito, Flavio Ossola, Kaci Phizackerley, Dita Rasper, Jacob Shaul, Xiaoyu Shen, Robert L Simmons, Dazhi Tang, Kyuto Tashiro, Qin Yue
IID572: A New Potentially Best-In-Class β-Lactamase Inhibitor. ACS infectious diseases 5 (7) (2019)
Xiaoyu Shen, Nicole V Johnson, Naomi N K Kreamer, S Whitney Barnes, John R Walker, Angela L Woods, David A Six, Charles R Dean
Defects in Efflux (oprM), β-Lactamase (ampC), and Lipopolysaccharide Transport (lptE) Genes Mediate Antibiotic Hypersusceptibility of Pseudomonas aeruginosa Strain Z61. Antimicrobial agents and chemotherapy 63 (7) (2019)
Adriana K Jones, Ruth E Caughlan, Angela L Woods, Kyoko Uehara, Lili Xie, S Whitney Barnes, John R Walker, Katherine V Thompson, Srijan Ranjitkar, Patrick S Lee, Charles R Dean
Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms. Antimicrobial agents and chemotherapy 64 (1) (2019)
Adriana K Jones, Srijan Ranjitkar, Sara Lopez, Cindy Li, Johanne Blais, Folkert Reck, Charles R Dean
Impact of Inducible blaDHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne blaDHA-1 Expression. Antimicrobial agents and chemotherapy 62 (10) (2018)
Charles R Dean, David T Barkan, Alun Bermingham, Johanne Blais, Fergal Casey, Anthony Casarez, Richard Colvin, John Fuller, Adriana K Jones, Cindy Li, Sara Lopez, Louis E Metzger, Mina Mostafavi, Ramadevi Prathapam, Dita Rasper, Folkert Reck, Alexey Ruzin, Jacob Shaul, Xiaoyu Shen, Robert L Simmons, Peter Skewes-Cox, Kenneth T Takeoka, Pramila Tamrakar, Tsuyoshi Uehara, Jun-Rong Wei
Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae. Antimicrobial agents and chemotherapy 62 (10) (2018)
Johanne Blais, Sara Lopez, Cindy Li, Alexey Ruzin, Srijan Ranjitkar, Charles R Dean, Jennifer A Leeds, Anthony Casarez, Robert L Simmons, Folkert Reck
In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae. Antimicrobial agents and chemotherapy 62 (10) (2018)
Mina Mostafavi, Lisha Wang, Lili Xie, Kenneth T Takeoka, Daryl L Richie, Fergal Casey, Alexey Ruzin, William S Sawyer, Christopher M Rath, Jun-Rong Wei, Charles R Dean
Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis. mSphere 3 (5) (2018)
Grazia Piizzi, David T Parker, Yunshan Peng, Markus Dobler, Anup Patnaik, Som Wattanasin, Eugene Liu, Francois Lenoir, Jill Nunez, John Kerrigan, David McKenney, Colin Osborne, Donghui Yu, Leanne Lanieri, Jade Bojkovic, JoAnn Dzink-Fox, Maria-Dawn Lilly, Elizabeth R Sprague, Yipin Lu, Hongming Wang, Srijan Ranjitkar, Lili Xie, Bing Wang, Meir Glick, Lawrence G Hamann, Ruben Tommasi, Xia Yang, Charles R Dean
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. Journal of medicinal chemistry 60 (12) (2017)
Jun-Rong Wei, Daryl L Richie, Mina Mostafavi, Louis E Metzger, Christopher M Rath, William S Sawyer, Kenneth T Takeoka, Charles R Dean
LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates. mSphere 2 (4) (2017)

Charles R Dean.css-eqlu8i{font-size:small;padding-left:4px;} (C R Dean)

Publication Activity (10 Years)

Top Topics

Top Venues

Charles R Dean (C R Dean)