Christian P R Hackenberger

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Chemical science

Angewandte Chemie (International ed. in English)

Chemical communications (Cambridge, England)

Chembiochem : a European journal of chemical biology

Leibniz-Institut für Molekulare Pharmakologie

Rheinisch Westfälische Technische Hochschule Aachen RWTH Aachen Fakultät für Mathematik Informatik und Naturwissenschaften (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leibniz-Institut für Molekulare Pharmakologie

Germany

Department Head :: Chemical Biology

Humboldt-Universität zu Berlin

Germany

Leibniz-Humboldt Professor (W3,Full professor) for Chemical Biology

Freie Universität Berlin Fachbereich Biologie Chemie Pharmazie

Germany

Associate Professor (W2) for Bioorganic Chemistry

Freie Universität Berlin Fachbereich Biologie Chemie Pharmazie

Germany

Emmy-Noether-Group leader

Freie Universität Berlin Fachbereich Biologie Chemie Pharmazie

Germany

Junior group leader as Liebig-Scholar (FCI)

Massachusetts Institute of Technology

United States

Postdoctoral work

Education History

Rheinisch Westfälische Technische Hochschule Aachen RWTH Aachen Fakultät für Mathematik Informatik und Naturwissenschaften

Germany

PHD

University of Wisconsin Madison

United States

MSC

Publications

Alen Koçak, Amal K Homer, Antonia Feida, Florian Telschow, Jacob L Gorenflos López, Cihan Baydaroğlu, Michael Gradzielski, Christian P R Hackenberger, Ulrike Alexiev, Oliver Seitz
Fluorogenic cell surface glycan labelling with fluorescence molecular rotor dyes and nucleic acid stains. Chemical communications (Cambridge, England) (2024)
Alen Koçak, Amal K Homer, Antonia Feida, Florian Telschow, Jacob L Gorenflos López, Cihan Baydaroğlu, Michael Gradzielski, Christian P R Hackenberger, Ulrike Alexiev, Oliver Seitz
Fluorogenic cell surface glycan labelling with fluorescence molecular rotor dyes and nucleic acid stains. Chemical communications (Cambridge, England) 60 (36) (2024)
Alen Koçak, Amal K Homer, Antonia Feida, Florian Telschow, Jacob L Gorenflos López, Cihan Baydaroğlu, Michael Gradzielski, Christian P R Hackenberger, Ulrike Alexiev, Oliver Seitz
Fluorogenic cell surface glycan labelling with fluorescence molecular rotor dyes and nucleic acid stains. Chemical communications (Cambridge, England) 60 (36) (2024)
Arseniy Galashov, Ekaterina Kazakova, Christian E Stieger, Christian P R Hackenberger, Oliver Seitz
Rapid building block-economic synthesis of long, multi- O -GalNAcylated MUC5AC tandem repeat peptides. Chemical science 15 (4) (2023)
Philipp Ochtrop, Jahaziel Jahzerah, Paul Machui, Isabelle Mai, Dominik Schumacher, Jonas Helma, Marc-André Kasper, Christian P R Hackenberger
Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent in vivo PK profile. Chemical science 14 (9) (2023)
Arseniy Galashov, Ekaterina Kazakova, Christian E Stieger, Christian P R Hackenberger, Oliver Seitz
Rapid building block-economic synthesis of long, multi- O -GalNAcylated MUC5AC tandem repeat peptides. Chemical science 15 (4) (2023)
Philipp Ochtrop, Jahaziel Jahzerah, Paul Machui, Isabelle Mai, Dominik Schumacher, Jonas Helma, Marc-André Kasper, Christian P R Hackenberger
Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent in vivo PK profile. Chemical science 14 (9) (2023)
Jacob L Gorenflos López, Peter Schmieder, Kristin Kemnitz-Hassanin, Hatice Ceyda Asikoglu, Arif Celik, Christian E Stieger, Dorothea Fiedler, Stephan Hinderlich, Christian P R Hackenberger
Real-time monitoring of the sialic acid biosynthesis pathway by NMR. Chemical science 14 (13) (2023)
Jan Vincent V Arafiles, Jonathan Franke, Luise Franz, Jacobo Gómez-González, Kristin Kemnitz-Hassanin, Christian P R Hackenberger
Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins. Journal of the American Chemical Society (2023)
Saskia Schmitt, Paul Machui, Isabelle Mai, Sarah Herterich, Swetlana Wunder, Philipp Cyprys, Marcus Gerlach, Philipp Ochtrop, Christian P R Hackenberger, Dominik Schumacher, Jonas Helma, Annette M Vogl, Marc-André Kasper
Design and evaluation of phosphonamidate-linked exatecan constructs for highly loaded, stable, and efficacious Antibody-Drug-Conjugates. Molecular cancer therapeutics (2023)
Abhishek Saha, Shaswati Mandal, Jan Vincent V Arafiles, Jacobo Gómez-González, Christian P R Hackenberger, Ashraf Brik
Structure-Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell-Penetrating Peptides for Live-Cell Delivery of Synthetic Proteins. Angewandte Chemie (International ed. in English) 61 (47) (2022)
Pascal M Engelhardt, Sebastián Florez-Rueda, Marco Drexelius, Jörg-Martin Neudörfl, Daniel Lauster, Christian P R Hackenberger, Ronald Kühne, Ines Neundorf, Hans-Günther Schmalz
Synthetic α-Helical Peptides as Potential Inhibitors of the ACE2 SARS-CoV-2 Interaction. Chembiochem : a European journal of chemical biology 23 (17) (2022)
Lutz Adam, Eva Müller, Kai Ludwig, Simon Klenk, Daniel Lauster, Susanne Liese, Andreas Herrmann, Christian P R Hackenberger
Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza Virus. Bioconjugate chemistry 33 (7) (2022)
Carolina Sarto, Sebastián Florez-Rueda, Mehrnoosh Arrar, Christian P R Hackenberger, Daniel Lauster, Santiago Di Lella
Atomistic insight into the essential binding event of ACE2-derived peptides to the SARS-CoV-2 spike protein. Biological chemistry 403 (5-6) (2022)
Sarah Hansen, Jan Vincent V Arafiles, Philipp Ochtrop, Christian P R Hackenberger
Modular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides. Chemical communications (Cambridge, England) 58 (60) (2022)
Christian E Stieger, Yerin Park, Mark A R de Geus, Dongju Kim, Christiane Huhn, J Sophia Slenczka, Philipp Ochtrop, Judith M Müchler, Roderich D Süssmuth, Johannes Broichhagen, Mu-Hyun Baik, Christian P R Hackenberger
DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angewandte Chemie (International ed. in English) 61 (41) (2022)
Maike Roas, Binje Vick, Marc-André Kasper, Marina Able, Harald Polzer, Marcus Gerlach, Elisabeth Kremmer, Judith S Hecker, Saskia Schmitt, Andreas Stengl, Verena Waller, Natascha Hohmann, Moreno Festini, Alexander Edmund Ludwig, Lisa Rohrbacher, Tobias Herold, Marion Subklewe, Katharina S Götze, Christian P R Hackenberger, Dominik Schumacher, Jonas Helma-Smets, Irmela Jeremias, Heinrich Leonhardt, Karsten Spiekermann
TARGETING FLT3 BY NEW-GENERATION ANTIBODY-DRUG-CONJUGATE IN COMBINATION WITH KINASE INHIBITORS FOR TREATMENT OF AML. Blood (2022)
Christian P R Hackenberger, Phillip E Dawson, Yong Xiang Chen, Hironobu Hojo
Modern Peptide and Protein Chemistry: Reaching New Heights. The Journal of organic chemistry 85 (3) (2021)
Yerin Park, Alice L Baumann, Hyejin Moon, Stephen Byrne, Marc-André Kasper, Songhwan Hwang, Han Sun, Mu-Hyun Baik, Christian P R Hackenberger
The mechanism behind enhanced reactivity of unsaturated phosphorus(v) electrophiles towards thiols. Chemical science 12 (23) (2021)
Anselm F L Schneider, Joerg Kallen, Johannes Ottl, Patrick C Reid, Sebastien Ripoche, Stephan Ruetz, Therese-Marie Stachyra, Samuel Hintermann, Christoph E Dumelin, Christian P R Hackenberger, Andreas L Marzinzik
Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors. RSC chemical biology 2 (6) (2021)
Christian E Stieger, Luise Franz, Frieder Körlin, Christian P R Hackenberger
Diethynyl Phosphinates for Cysteine-Selective Protein Labeling and Disulfide Rebridging. Angewandte Chemie (International ed. in English) 60 (28) (2021)
Anselm F L Schneider, Laila S Benz, Martin Lehmann, Christian P R Hackenberger
Cell-Permeable Nanobodies Allow Dual-Color Super-Resolution Microscopy in Untransfected Living Cells. Angewandte Chemie (International ed. in English) 60 (40) (2021)
Anselm F L Schneider, Marina Kithil, Maria Cristina Cardoso, Martin Lehmann, Christian P R Hackenberger
Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives. Nature chemistry 13 (6) (2021)
Bingjia Yan, Wenyi Li, Christian P R Hackenberger
A silyl ether-protected building block for O-GlcNAcylated peptide synthesis to enable one-pot acidic deprotection. Organic & biomolecular chemistry 19 (37) (2021)
Daniel Lauster, Simon Klenk, Kai Ludwig, Saba Nojoumi, Sandra Behren, Lutz Adam, Marlena Stadtmüller, Sandra Saenger, Stephanie Zimmler, Katja Hönzke, Ling Yao, Ute Hoffmann, Markus Bardua, Alf Hamann, Martin Witzenrath, Leif E Sander, Thorsten Wolff, Andreas C Hocke, Stefan Hippenstiel, Sacha De Carlo, Jens Neudecker, Klaus Osterrieder, Nediljko Budisa, Roland R Netz, Christoph Böttcher, Susanne Liese, Andreas Herrmann, Christian P R Hackenberger
Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry. Nature nanotechnology 15 (5) (2020)
Anett Hauser, Eleftheria Poulou, Fabian Müller, Peter Schmieder, Christian P R Hackenberger
Synthesis and Evaluation of Non-Hydrolyzable Phospho-Lysine Peptide Mimics. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (7) (2020)
Anett Hauser, Songhwan Hwang, Han Sun, Christian P R Hackenberger
Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase. Chemical science 11 (47) (2020)
Marc-André Kasper, Marcus Gerlach, Anselm F L Schneider, Christiane Groneberg, Philipp Ochtrop, Stefanie Boldt, Dominik Schumacher, Jonas Helma, Heinrich Leonhardt, Mathias Christmann, Christian P R Hackenberger
N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates. Chembiochem : a European journal of chemical biology 21 (1-2) (2020)
Anett Hauser, Eleftheria Poulou, Fabian Müller, Peter Schmieder, Christian P R Hackenberger
Synthesis and Evaluation of Non-Hydrolyzable Phospho-Lysine Peptide Mimics. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (7) (2020)
Marc-André Kasper, Andreas Stengl, Philipp Ochtrop, Marcus Gerlach, Tina Stoschek, Dominik Schumacher, Jonas Helma, Martin Penkert, Eberhard Krause, Heinrich Leonhardt, Christian P R Hackenberger
Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates. Angewandte Chemie (International ed. in English) 58 (34) (2019)
Marc-André Kasper, Maria Glanz, Andreas Stengl, Martin Penkert, Simon Klenk, Tom Sauer, Dominik Schumacher, Jonas Helma, Eberhard Krause, Maria Cristina Cardoso, Heinrich Leonhardt, Christian P R Hackenberger
Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations. Angewandte Chemie (International ed. in English) 58 (34) (2019)
Anselm F L Schneider, Antoine L D Wallabregue, Luise Franz, Christian P R Hackenberger
Targeted Subcellular Protein Delivery Using Cleavable Cyclic Cell-Penetrating Peptides. Bioconjugate chemistry 30 (2) (2019)
Caroline Apel, Marc-André Kasper, Christian E Stieger, Christian P R Hackenberger, Mathias Christmann
Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal. Organic letters 21 (24) (2019)
Marc-André Kasper, Maria Glanz, Andreas Oder, Peter Schmieder, Jens P von Kries, Christian P R Hackenberger
Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization. Chemical science 10 (25) (2019)
Andreas Stengl, Marcus Gerlach, Marc-André Kasper, Christian P R Hackenberger, Heinrich Leonhardt, Dominik Schumacher, Jonas Helma
TuPPL: Tub-tag mediated C-terminal protein-protein-ligation using complementary click-chemistry handles. Organic & biomolecular chemistry 17 (20) (2019)
Daniel Lauster, Maria Glanz, Markus Bardua, Kai Ludwig, Markus Hellmund, Ute Hoffmann, Alf Hamann, Christoph Böttcher, Rainer Haag, Christian P R Hackenberger, Andreas Herrmann
Multivalent Peptide-Nanoparticle Conjugates for Influenza-Virus Inhibition. Angewandte Chemie (International ed. in English) 56 (21) (2017)
Stephan Hinderlich, Martin Neuenschwander, Paul R Wratil, Andreas Oder, Michael Lisurek, Long D Nguyen, Jens P von Kries, Christian P R Hackenberger
Small Molecules Targeting Human N-Acetylmannosamine Kinase. Chembiochem : a European journal of chemical biology 18 (13) (2017)
Dominik Schumacher, Oliver Lemke, Jonas Helma, Lena Gerszonowicz, Verena Waller, Tina Stoschek, Patrick M Durkin, Nediljko Budisa, Heinrich Leonhardt, Bettina G Keller, Christian P R Hackenberger
Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling. Chemical science 8 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christian P R Hackenberger