Christoph Handschin

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 25

Top Venues

Nature communications

Aging cell

Proceedings of the National Academy of Sciences of the United States of America

The Journal of physiology

Universität Basel Department Biozentrum

Universität Basel Department Biozentrum (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universität Basel Department Biozentrum

Switzerland

Professor :: Biozentrum

Universität Basel Department Biozentrum

Switzerland

Associate Professor :: Biozentrum

University of Zurich

Switzerland

Assistant Professor :: Institute of Physiology, Zurich Center for Integrative Human Physiology

Dana Farber Cancer Institute

United States

Instructor :: Cancer Biology

Dana Farber Cancer Institute

United States

Postdoctoral fellow :: Cancer Biology

Universität Basel Department Biozentrum

Switzerland

Postdoctoral fellow :: Biozentrum

Education History

Universität Basel Department Biozentrum

Switzerland

PHD :: Biozentrum

University of Basel

Switzerland

MSC :: Biozentrum

Publications

Shivani Mansingh, Geraldine Maier, Julien Delezie, Pål O Westermark, Danilo Ritz, Wandrille Duchemin, Gesa Santos, Bettina Karrer-Cardel, Stefan A Steurer, Urs Albrecht, Christoph Handschin
More than the clock: distinct regulation of muscle function and metabolism by PER2 and RORα. The Journal of physiology (2024)
Regula Furrer, Barbara Heim, Svenia Schmid, Sedat Dilbaz, Volkan Adak, Karl J V Nordström, Danilo Ritz, Stefan A Steurer, Jörn Walter, Christoph Handschin
Molecular control of endurance training adaptation in male mouse skeletal muscle. Nature metabolism (2023)
Aurel B Leuchtmann, Yasmine Afifi, Danilo Ritz, Christoph Handschin
Effects of high-resistance wheel running on hallmarks of endurance and resistance training adaptations in mice. Physiological reports 11 (11) (2023)
Laura M de Smalen, Anastasiya Börsch, Aurel B Leuchtmann, Jonathan F Gill, Danilo Ritz, Mihaela Zavolan, Christoph Handschin
Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α. Proceedings of the National Academy of Sciences of the United States of America 120 (36) (2023)
Katerina Novakova, Michael Török, Miljenko Panajatovic, Jamal Bouitbir, François H T Duong, Christoph Handschin, Stephan Krähenbühl
PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle. International journal of molecular sciences 23 (20) (2022)
Joaquín Pérez-Schindler, Bastian Kohl, Konstantin Schneider-Heieck, Aurel B Leuchtmann, Carlos Henríquez Olguín, Volkan Adak, Geraldine Maier, Julien Delezie, Thomas Sakoparnig, Elyzabeth Vargas-Fernández, Bettina Karrer-Cardel, Danilo Ritz, Alexander Schmidt, Maria Hondele, Thomas E Jensen, Sebastian Hiller, Christoph Handschin
RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates. Proceedings of the National Academy of Sciences of the United States of America 118 (36) (2022)
Daniel J Ham, Anastasiya Börsch, Kathrin Chojnowska, Shuo Lin, Aurel B Leuchtmann, Alexander S Ham, Marco Thürkauf, Julien Delezie, Regula Furrer, Dominik Burri, Michael Sinnreich, Christoph Handschin, Lionel A Tintignac, Mihaela Zavolan, Nitish Mittal, Markus A Rüegg
Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle. Nature communications 13 (1) (2022)
Aurel B Leuchtmann, Regula Furrer, Stefan A Steurer, Konstantin Schneider-Heieck, Bettina Karrer-Cardel, Yves Sagot, Christoph Handschin
Interleukin-6 potentiates endurance training adaptation and improves functional capacity in old mice. Journal of cachexia, sarcopenia and muscle 13 (2) (2022)
Regula Furrer, Christoph Handschin
Drugs, clocks and exercise in ageing: hype and hope, fact and fiction. The Journal of physiology (2022)
Daniel J Ham, Anastasiya Börsch, Kathrin Chojnowska, Shuo Lin, Aurel B Leuchtmann, Alexander S Ham, Marco Thürkauf, Julien Delezie, Regula Furrer, Dominik Burri, Michael Sinnreich, Christoph Handschin, Lionel A Tintignac, Mihaela Zavolan, Nitish Mittal, Markus A Rüegg
Author Correction: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle. Nature communications 13 (1) (2022)
Regula Furrer, Annaïse J Jauch, Tata Nageswara Rao, Sedat Dilbaz, Peter Rhein, Stefan A Steurer, Mike Recher, Radek C Skoda, Christoph Handschin
Remodeling of metabolism and inflammation by exercise ameliorates tumor-associated anemia. Science advances 7 (37) (2021)
Geraldine Maier, Julien Delezie, Pål O Westermark, Gesa Santos, Danilo Ritz, Christoph Handschin
Transcriptomic, proteomic and phosphoproteomic underpinnings of daily exercise performance and zeitgeber activity of training in mouse muscle. The Journal of physiology (2021)
Fabienne Battilana, Stefan Steurer, Giorgio Rizzi, Ana C Delgado, Kelly R Tan, Christoph Handschin
Exercise-linked improvement in age-associated loss of balance is associated with increased vestibular input to motor neurons. Aging cell 19 (12) (2020)
Daniel J Ham, Anastasiya Börsch, Shuo Lin, Marco Thürkauf, Martin Weihrauch, Judith R Reinhard, Julien Delezie, Fabienne Battilana, Xueyong Wang, Marco S Kaiser, Maitea Guridi, Michael Sinnreich, Mark M Rich, Nitish Mittal, Lionel A Tintignac, Christoph Handschin, Mihaela Zavolan, Markus A Rüegg
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia. Nature communications 11 (1) (2020)
Julien Delezie, Martin Weihrauch, Geraldine Maier, Rocío Tejero, Daniel J Ham, Jonathan F Gill, Bettina Karrer-Cardel, Markus A Rüegg, Lucía Tabares, Christoph Handschin
BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America 116 (32) (2019)
Jonathan F Gill, Julien Delezie, Gesa Santos, Shawn McGuirk, Svenia Schnyder, Stephan Frank, Martin Rausch, Julie St-Pierre, Christoph Handschin
Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging. Aging cell 18 (5) (2019)
Anne I Krämer, Christoph Handschin
How Epigenetic Modifications Drive the Expression and Mediate the Action of PGC-1α in the Regulation of Metabolism. International journal of molecular sciences 20 (21) (2019)
Leandro Z Agudelo, Duarte M S Ferreira, Shamim Dadvar, Igor Cervenka, Lars Ketscher, Manizheh Izadi, Liu Zhengye, Regula Furrer, Christoph Handschin, Tomas Venckunas, Marius Brazaitis, Sigitas Kamandulis, Johanna T Lanner, Jorge L Ruas
Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. Nature communications 10 (1) (2019)
Alexis Ruiz, Erez Dror, Christoph Handschin, Regula Furrer, Joaquin Perez-Schindler, Christoph Bachmann, Susan Treves, Francesco Zorzato
Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance. Scientific reports 8 (1) (2018)
Deana Haralampieva, Souzan Salemi, Thomas Betzel, Ivana Dinulovic, Stefanie D Krämer, Roger Schibli, Tullio Sulser, Christoph Handschin, Simon M Ametamey, Daniel Eberli
Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma. Stem cells international 2018 (2018)
Svenia Schnyder, Kristoffer Svensson, Bettina Cardel, Christoph Handschin
Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice. American journal of physiology. Endocrinology and metabolism 312 (5) (2017)
Jonathan F Gill, Gesa Santos, Svenia Schnyder, Christoph Handschin
PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice. Aging cell 17 (1) (2017)
Ivana Dinulovic, Regula Furrer, Sabrina Di Fulvio, Arnaud Ferry, Markus Beer, Christoph Handschin
PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle. Skeletal muscle 6 (2016)
Kristoffer Svensson, Svenia Schnyder, Bettina Cardel, Christoph Handschin
Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice. PloS one 11 (7) (2016)
Ivana Dinulovic, Regula Furrer, Markus Beer, Arnaud Ferry, Bettina Cardel, Christoph Handschin
Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche. Skeletal muscle 6 (1) (2016)
Kristoffer Svensson, Svenia Schnyder, Verena Albert, Bettina Cardel, Luca Quagliata, Luigi M Terracciano, Christoph Handschin
Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α). The Journal of biological chemistry 290 (26) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christoph Handschin