Colin Adrain

ResearcherID Scopus Author ID Scopus Author ID Ciência ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Venues

Nature communications

Life science alliance

Cellular and molecular life sciences : CMLS

The FEBS journal

Instituto Gulbenkian de Ciencia

Smurfit Institute of Genetics Trinity College (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Instituto Gulbenkian de Ciencia Jun 01 2013

Portugal

Principal Investigator / Lab Head :: Membrane Traffic Lab

MRC Laboratory of Molecular Biology Feb 20 2007 - May 20 2013

United Kingdom

Postdoctoral Fellow (supported by EMBO & HFSP) :: Division of Cell Biology

Smurfit Institute of Genetics Trinity College Jul 03 2003 - Dec 31 2006

Ireland

Postdoc :: Department of Genetics

National University of Ireland Department of Biology Oct 01 1997 - Oct 01 1998

Ireland

Research Assistant :: Department of Biology

Education History

Smurfit Institute of Genetics Trinity College Oct 01 1998 - Jul 02 2003

Ireland

PHD :: Department of Genetics

Queen Mary University of London Sep 01 1994 - Jul 09 1997

United Kingdom

BSC :: Department of Genetics

Publications

Katharina Bläsius, Lena Ludwig, Sarah Knapp, Charlotte Flaßhove, Friederike Sonnabend, Diandra Keller, Nikola Tacken, Xintong Gao, Selcan Kahveci-Türköz, Caroline Grannemann, Aaron Babendreyer, Colin Adrain, Sebastian Huth, Jens Malte Baron, Andreas Ludwig, Stefan Düsterhöft
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Julia D Knopf, Susanne S Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J Theobald, Jan Rybniker, Colin Adrain, Marius K Lemberg
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nature communications 15 (1) (2024)
Julia D Knopf, Susanne S Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J Theobald, Jan Rybniker, Colin Adrain, Marius K Lemberg
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nature communications 15 (1) (2024)
Katharina Bläsius, Lena Ludwig, Sarah Knapp, Charlotte Flaßhove, Friederike Sonnabend, Diandra Keller, Nikola Tacken, Xintong Gao, Selcan Kahveci-Türköz, Caroline Grannemann, Aaron Babendreyer, Colin Adrain, Sebastian Huth, Jens Malte Baron, Andreas Ludwig, Stefan Düsterhöft
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Julia D Knopf, Susanne S Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J Theobald, Jan Rybniker, Colin Adrain, Marius K Lemberg
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nature communications 15 (1) (2024)
Julia D Knopf, Susanne S Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J Theobald, Jan Rybniker, Colin Adrain, Marius K Lemberg
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nature communications 15 (1) (2024)
Katharina Bläsius, Lena Ludwig, Sarah Knapp, Charlotte Flaßhove, Friederike Sonnabend, Diandra Keller, Nikola Tacken, Xintong Gao, Selcan Kahveci-Türköz, Caroline Grannemann, Aaron Babendreyer, Colin Adrain, Sebastian Huth, Jens Malte Baron, Andreas Ludwig, Stefan Düsterhöft
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Julia D Knopf, Susanne S Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J Theobald, Jan Rybniker, Colin Adrain, Marius K Lemberg
RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nature communications 15 (1) (2024)
Marina Badenes, Emma Burbridge, Ioanna Oikonomidi, Abdulbasit Amin, Érika Carvalho, Lindsay Kosack, Camila Mariano, Pedro M Domingos, Pedro Faísca, Colin Adrain
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth. Life science alliance 6 (4) (2023)
Marina Badenes, Emma Burbridge, Ioanna Oikonomidi, Abdulbasit Amin, Érika Carvalho, Lindsay Kosack, Camila Mariano, Pedro M Domingos, Pedro Faísca, Colin Adrain
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth. Life science alliance 6 (4) (2023)
Marina Badenes, Emma Burbridge, Ioanna Oikonomidi, Abdulbasit Amin, Érika Carvalho, Lindsay Kosack, Camila Mariano, Pedro M Domingos, Pedro Faísca, Colin Adrain
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth. Life science alliance 6 (4) (2023)
Marina Badenes, Emma Burbridge, Ioanna Oikonomidi, Abdulbasit Amin, Érika Carvalho, Lindsay Kosack, Camila Mariano, Pedro M Domingos, Pedro Faísca, Colin Adrain
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth. Life science alliance 6 (4) (2023)
Emma Burbridge, Colin Adrain
Organelle homeostasis: from cellular mechanisms to disease. The FEBS journal 289 (22) (2022)
Xianhe Li, Julian Straub, Tânia Catarina Medeiros, Chahat Mehra, Fabian den Brave, Esra Peker, Ilian Atanassov, Katharina Stillger, Jonas Benjamin Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena F Pernas
Mitochondria shed their outer membrane in response to infection-induced stress. Science (New York, N.Y.) 375 (6577) (2022)
Catarina J Gaspar, Lígia C Vieira, Cristiana C Santos, John C Christianson, David Jakubec, Kvido Strisovsky, Colin Adrain, Pedro M Domingos
EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel. EMBO reports 23 (1) (2021)
Colin Adrain
Systemic and cellular metabolism: the cause of and remedy for disease? The FEBS journal 288 (12) (2021)
Colin Adrain, Miguel A Cavadas
The complex life of rhomboid pseudoproteases. The FEBS journal 287 (19) (2020)
Marina Badenes, Colin Adrain
iRhom2 and TNF: Partners or enemies? Science signaling 12 (605) (2019)
Ioanna Oikonomidi, Emma Burbridge, Miguel Cavadas, Graeme Sullivan, Blanka Collis, Heike Naegele, Danielle Clancy, Jana Brezinova, Tianyi Hu, Andrea Bileck, Christopher Gerner, Alfonso Bolado, Alex von Kriegsheim, Seamus J Martin, Florian Steinberg, Kvido Strisovsky, Colin Adrain
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE. eLife 7 (2018)

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Publication Activity (10 Years)

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Colin Adrain