Christian Münch

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 52

Top Venues

Cells

The Journal of experimental medicine

Molecular pharmaceutics

Cell death discovery

Goethe-Universität Frankfurt am Main

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Goethe-Universität Frankfurt am Main

Germany

Emmy Noether Group Leader :: Biochemistry II

Goethe University Frankfurt

Germany

Independent Group Leader :: Biochemistry II

Harvard Medical School

United States

Postdoctoral Fellow :: Cell Biology

MRC Laboratory of Molecular Biology

United Kingdom

Investigator Scientist :: Neurobiology

Education History

University of Cambridge

United Kingdom

PHD :: Laboratory of Molecular Biology

Publications

David Brenner, Kirsten Sieverding, Jahnavi Srinidhi, Susanne Zellner, Christopher Secker, Rüstem Yilmaz, Julia Dyckow, Shady Amr, Anna Ponomarenko, Esra Tunaboylu, Yasmin Douahem, Joana S Schlag, Lucía Rodríguez Martínez, Georg Kislinger, Cornelia Niemann, Karsten Nalbach, Wolfgang P Ruf, Jonathan Uhl, Johanna Hollenbeck, Lucas Schirmer, Alberto Catanese, Christian S Lobsiger, Karin M Danzer, Deniz Yilmazer-Hanke, Christian Münch, Philipp Koch, Axel Freischmidt, Martina Fetting, Christian Behrends, Rosanna Parlato, Jochen H Weishaupt
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice. The Journal of experimental medicine 221 (5) (2024)
David Brenner, Kirsten Sieverding, Jahnavi Srinidhi, Susanne Zellner, Christopher Secker, Rüstem Yilmaz, Julia Dyckow, Shady Amr, Anna Ponomarenko, Esra Tunaboylu, Yasmin Douahem, Joana S Schlag, Lucía Rodríguez Martínez, Georg Kislinger, Cornelia Niemann, Karsten Nalbach, Wolfgang P Ruf, Jonathan Uhl, Johanna Hollenbeck, Lucas Schirmer, Alberto Catanese, Christian S Lobsiger, Karin M Danzer, Deniz Yilmazer-Hanke, Christian Münch, Philipp Koch, Axel Freischmidt, Martina Fetting, Christian Behrends, Rosanna Parlato, Jochen H Weishaupt
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice. The Journal of experimental medicine 221 (5) (2024)
Benedikt Sauer, Nadja I Lorenz, Iris Divé, Kevin Klann, Anna-Luisa Luger, Hans Urban, Jan-Hendrik Schröder, Joachim P Steinbach, Christian Münch, Michael W Ronellenfitsch
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death. Cell death discovery 10 (1) (2024)
David Brenner, Kirsten Sieverding, Jahnavi Srinidhi, Susanne Zellner, Christopher Secker, Rüstem Yilmaz, Julia Dyckow, Shady Amr, Anna Ponomarenko, Esra Tunaboylu, Yasmin Douahem, Joana S Schlag, Lucía Rodríguez Martínez, Georg Kislinger, Cornelia Niemann, Karsten Nalbach, Wolfgang P Ruf, Jonathan Uhl, Johanna Hollenbeck, Lucas Schirmer, Alberto Catanese, Christian S Lobsiger, Karin M Danzer, Deniz Yilmazer-Hanke, Christian Münch, Philipp Koch, Axel Freischmidt, Martina Fetting, Christian Behrends, Rosanna Parlato, Jochen H Weishaupt
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice. The Journal of experimental medicine 221 (5) (2024)
Benedikt Sauer, Nadja I Lorenz, Iris Divé, Kevin Klann, Anna-Luisa Luger, Hans Urban, Jan-Hendrik Schröder, Joachim P Steinbach, Christian Münch, Michael W Ronellenfitsch
Mammalian target of rapamycin inhibition protects glioma cells from temozolomide-induced cell death. Cell death discovery 10 (1) (2024)
David Brenner, Kirsten Sieverding, Jahnavi Srinidhi, Susanne Zellner, Christopher Secker, Rüstem Yilmaz, Julia Dyckow, Shady Amr, Anna Ponomarenko, Esra Tunaboylu, Yasmin Douahem, Joana S Schlag, Lucía Rodríguez Martínez, Georg Kislinger, Cornelia Niemann, Karsten Nalbach, Wolfgang P Ruf, Jonathan Uhl, Johanna Hollenbeck, Lucas Schirmer, Alberto Catanese, Christian S Lobsiger, Karin M Danzer, Deniz Yilmazer-Hanke, Christian Münch, Philipp Koch, Axel Freischmidt, Martina Fetting, Christian Behrends, Rosanna Parlato, Jochen H Weishaupt
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice. The Journal of experimental medicine 221 (5) (2024)
Anshu Bhattacharya, Rukmini Mukherjee, Santosh Kumar Kuncha, Melinda Elaine Brunstein, Rajeshwari Rathore, Stephan Junek, Christian Münch, Ivan Đikić
A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Nature cell biology (2023)
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. Cells 12 (1) (2023)
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. Cells 12 (1) (2023)
Pablo Sánchez-Martín, Franziska Kriegenburg, Ludovico Alves, Julius Adam, Jana Elsaesser, Riccardo Babic, Hector Mancilla, Mariya Licheva, Georg Tascher, Christian Münch, Stefan Eimer, Claudine Kraft
ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy. Journal of cell science (2023)
Raquel S Pereira, Rahul Kumar, Alessia Cais, Lara Paulini, Alisa Kahler, Jimena Bravo, Valentina R Minciacchi, Theresa Krack, Eric Kowarz, Costanza Zanetti, Parimala Sonika Godavarthy, Fabian Hoeller, Pablo Llavona, Tabea Stark, Georg Tascher, Daniel Nowak, Eshwar Meduri, Brian James Patrick Huntly, Christian Münch, Francesco Pampaloni, Rolf Marschalek, Daniela S Krause
Distinct and targetable role of calcium-sensing receptor in leukaemia. Nature communications 14 (1) (2023)
Christian Münch, Janine Kirstein
Protein quality control: from molecular mechanisms to therapeutic intervention-EMBO workshop, May 21-26 2023, Srebreno, Croatia. Cell stress & chaperones (2023)
Carina R Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M Al-Shami, Lisa Schlicker, Felix C E Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A Calzado, Martin Eilers, Nikita Popov, Mathias T Rosenfeldt, Markus Elmar Diefenbacher, Almut Schulze
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer. Cell death and differentiation (2023)
F X Reymond Sutandy, Ines Gößner, Georg Tascher, Christian Münch
A cytosolic surveillance mechanism activates the mitochondrial UPR. Nature (2023)
Sarah Rehbein, Anna-Lena Possmayer, Süleyman Bozkurt, Catharina Lotsch, Julia Gerstmeier, Michael C Burger, Stefan Momma, Claudia Maletzki, Carl Friedrich Classen, Thomas M Freiman, Daniel Dubinski, Katrin Lamszus, Brett W Stringer, Christel Herold-Mende, Christian Münch, Donat Kögel, Benedikt Linder
Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells. Cancers 15 (21) (2023)
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. Cells 12 (1) (2023)
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1. Cells 12 (1) (2023)
Silvia Kuntschar, Giulia Cardamone, Kevin Klann, Rebekka Bauer, Sofie Patrizia Meyer, Rebecca Raue, Peter Rappl, Christian Münch, Bernhard Brüne, Tobias Schmid
Mmp12 Is Translationally Regulated in Macrophages during the Course of Inflammation. International journal of molecular sciences 24 (23) (2023)
Jana Key, Suzana Gispert, Lieke Koornneef, Esther Sleddens-Linkels, Aneesha Kohli, Sylvia Torres-Odio, Gabriele Koepf, Shady Amr, Marina Reichlmeir, Patrick N Harter, Andrew Phillip West, Christian Münch, Willy M Baarends, Georg Auburger
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2. Cells 12 (1) (2022)
F X Reymond Sutandy, Rebecca George Tharyan, Christian Münch
The beginning of a new era: pioneering direct screens for RNA modulators. Signal transduction and targeted therapy 7 (1) (2022)
Iris Divé, Kevin Klann, Jonas B Michaelis, Dennis Heinzen, Joachim P Steinbach, Christian Münch, Michael W Ronellenfitsch
Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autophagy-independent manner. Cell death discovery 8 (1) (2022)
Sebastian E Koschade, Georg Tascher, Bhavesh S Parmar, Christian H Brandts, Christian Münch
SpinTip: A Simple, Robust, and Versatile Preanalytical Method for Microscale Suspension Cell Proteomics. Journal of proteome research 21 (11) (2022)
Marcel Walther, Pia Katharina Vestweber, Shafreena Kühn, Ulrich Rieger, Jasmin Schäfer, Christian Münch, Sarah Vogel-Kindgen, Viktoria Planz, Maike Windbergs
Bioactive Insulin-Loaded Electrospun Wound Dressings for Localized Drug Delivery and Stimulation of Protein Expression Associated with Wound Healing. Molecular pharmaceutics (2022)
Jana Key, Suzana Gispert, Lieke Koornneef, Esther Sleddens-Linkels, Aneesha Kohli, Sylvia Torres-Odio, Gabriele Koepf, Shady Amr, Marina Reichlmeir, Patrick N Harter, Andrew Phillip West, Christian Münch, Willy M Baarends, Georg Auburger
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2. Cells 12 (1) (2022)
Marcel Walther, Pia Katharina Vestweber, Shafreena Kühn, Ulrich Rieger, Jasmin Schäfer, Christian Münch, Sarah Vogel-Kindgen, Viktoria Planz, Maike Windbergs
Bioactive Insulin-Loaded Electrospun Wound Dressings for Localized Drug Delivery and Stimulation of Protein Expression Associated with Wound Healing. Molecular pharmaceutics 20 (1) (2022)
Jana Key, Suzana Gispert, Lieke Koornneef, Esther Sleddens-Linkels, Aneesha Kohli, Sylvia Torres-Odio, Gabriele Koepf, Shady Amr, Marina Reichlmeir, Patrick N Harter, Andrew Phillip West, Christian Münch, Willy M Baarends, Georg Auburger
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2. Cells 12 (1) (2022)
Jana Key, Suzana Gispert, Lieke Koornneef, Esther Sleddens-Linkels, Aneesha Kohli, Sylvia Torres-Odio, Gabriele Koepf, Shady Amr, Marina Reichlmeir, Patrick N Harter, Andrew Phillip West, Christian Münch, Willy M Baarends, Georg Auburger
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2. Cells 12 (1) (2022)
Xianhe Li, Julian Straub, Tânia Catarina Medeiros, Chahat Mehra, Fabian den Brave, Esra Peker, Ilian Atanassov, Katharina Stillger, Jonas Benjamin Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena F Pernas
Mitochondria shed their outer membrane in response to infection-induced stress. Science (New York, N.Y.) 375 (6577) (2022)
Sebastian E Koschade, Kevin Klann, Shabnam Shaid, Binje Vick, Jan A Stratmann, Marlyn Thölken, Laura M Meyer, The Duy Nguyen, Julia Campe, Laura M Moser, Susanna Hock, Fatima Baker, Christian T Meyer, Frank Wempe, Hubert Serve, Evelyn Ullrich, Irmela Jeremias, Christian Münch, Christian H Brandts
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia. Leukemia 36 (10) (2022)
Kevin Klann, Christian Münch
PBLMM: Peptide-based linear mixed models for differential expression analysis of shotgun proteomics data. Journal of cellular biochemistry 123 (3) (2022)
Marcel Walther, Pia Katharina Vestweber, Shafreena Kühn, Ulrich Rieger, Jasmin Schäfer, Christian Münch, Sarah Vogel-Kindgen, Viktoria Planz, Maike Windbergs
Bioactive Insulin-Loaded Electrospun Wound Dressings for Localized Drug Delivery and Stimulation of Protein Expression Associated with Wound Healing. Molecular pharmaceutics 20 (1) (2022)
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas Benjamin Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus. The EMBO journal (2022)
Daniel Schmitt, Süleyman Bozkurt, Pascale Henning-Domres, Heike Huesmann, Stefan Eimer, Laura Bindila, Christian Behrends, Emily Boyle, Florian Wilfling, Georg Tascher, Christian Münch, Christian Behl, Andreas Kern
Lipid and protein content profiling of isolated native autophagic vesicles. EMBO reports 23 (12) (2022)
Marcel Walther, Pia Katharina Vestweber, Shafreena Kühn, Ulrich Rieger, Jasmin Schäfer, Christian Münch, Sarah Vogel-Kindgen, Viktoria Planz, Maike Windbergs
Bioactive Insulin-Loaded Electrospun Wound Dressings for Localized Drug Delivery and Stimulation of Protein Expression Associated with Wound Healing. Molecular pharmaceutics 20 (1) (2022)
Jonas Benjamin Michaelis, Melinda Elaine Brunstein, Süleyman Bozkurt, Ludovico Alves, Martin Wegner, Manuel Kaulich, Christian Pohl, Christian Münch
Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy. Nature communications 13 (1) (2022)
Aneesha Kohli, Lucie Sauerhering, Sarah K Fehling, Kevin Klann, Helmut Geiger, Stephan Becker, Benjamin Koch, Patrick C Baer, Thomas Strecker, Christian Münch
Proteomic landscape of SARS-CoV-2- and MERS-CoV-infected primary human renal epithelial cells. Life science alliance 5 (5) (2022)
Sylvain Delaunay, Gloria Pascual, Bohai Feng, Kevin Klann, Mikaela Behm, Agnes Hotz-Wagenblatt, Karsten Richter, Karim Zaoui, Esther Herpel, Christian Münch, Sabine Dietmann, Jochen Hess, Salvador Aznar Benitah, Michaela Frye
Mitochondrial RNA modifications shape metabolic plasticity in metastasis. Nature 607 (7919) (2022)
Julia Gerstmeier, Anna-Lena Possmayer, Süleyman Bozkurt, Marina E Hoffmann, Ivan Dikic, Christel Herold-Mende, Michael C Burger, Christian Münch, Donat Kögel, Benedikt Linder
Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide. Cancers 13 (14) (2021)
Cristian Prieto-Garcia, Oliver Hartmann, Michaela Reissland, Thomas Fischer, Carina R Maier, Mathias T Rosenfeldt, Christina Schülein-Völk, Kevin Klann, Reinhard Kalb, Ivan Đikić, Christian Münch, Markus Elmar Diefenbacher
Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway. Cell death and differentiation (2021)
Alec Geßner, Benjamin Koch, Kevin Klann, Dominik Christian Fuhrmann, Samira Farmand, Ralf Schubert, Christian Münch, Helmut Geiger, Patrick C Baer
Characterization of Extracellular Vesicles from Preconditioned Human Adipose-Derived Stromal/Stem Cells. International journal of molecular sciences 22 (6) (2021)
Rodrigo A Gama-Brambila, Jie Chen, Yasamin Dabiri, Georg Tascher, Václav Němec, Christian Münch, Guangqi Song, Stefan Knapp, Xinlai Cheng
A Chemical Toolbox for Labeling and Degrading Engineered Cas Proteins. JACS Au 1 (6) (2021)
Ömer Güllülü, Stephanie Hehlgans, Benjamin E Mayer, Ines Gößner, Chrysi Petraki, Melanie Hoffmann, Maximilian J Dombrowsky, Patrick Kunzmann, Kay Hamacher, Klaus Strebhardt, Emmanouil Fokas, Claus Rödel, Christian Münch, Franz Rödel
A Spatial and Functional Interaction of a Heterotetramer Survivin-DNA-PKcs Complex in DNA Damage Response. Cancer research 81 (9) (2021)
Nina Meyer, Lisa Henkel, Benedikt Linder, Svenja Zielke, Georg Tascher, Sandra Trautmann, Gerd Geisslinger, Christian Münch, Simone Fulda, Irmgard Tegeder, Donat Kögel
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death. Autophagy 17 (11) (2021)
Kevin Klann, Christian Münch
Instrument Logic Increases Identifications during Mutliplexed Translatome Measurements. Analytical chemistry 92 (12) (2020)
Denisa Bojkova, Kevin Klann, Benjamin Florian Koch, Marek Widera, David Krause, Sandra Ciesek, Jindrich Cinatl, Christian Münch
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets. Nature 583 (7816) (2020)
Denisa Bojkova, Marco Bechtel, Katie-May McLaughlin, Jake E McGreig, Kevin Klann, Carla Bellinghausen, Gernot G U Rohde, Danny Jonigk, Peter Braubach, Sandra Ciesek, Christian Münch, Mark N Wass, Martin Michaelis, Jindrich Cinatl
Aprotinin Inhibits SARS-CoV-2 Replication. Cells 9 (11) (2020)
Tabea Osthues, Béla Zimmer, Vittoria Rimola, Kevin Klann, Karin Schilling, Praveen Mathoor, Carlo Angioni, Andreas Weigert, Gerd Geisslinger, Christian Münch, Klaus Scholich, Marco Sisignano
The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain. Cells 9 (7) (2020)
Kevin Klann, Christian Münch
Unbiased translation proteomics upon cell stress. Molecular & cellular oncology 7 (4) (2020)
Susanne Pitzius, Christian Osterburg, Jakob Gebel, Georg Tascher, Birgit Schäfer, Huiqing Zhou, Christian Münch, Volker Dötsch
TA*p63 and GTAp63 achieve tighter transcriptional regulation in quality control by converting an inhibitory element into an additional transactivation domain. Cell death & disease 10 (10) (2019)
The Duy Nguyen, Shabnam Shaid, Olesya Vakhrusheva, Sebastian E Koschade, Kevin Klann, Marlyn Thölken, Fatima Baker, Jing Zhang, Thomas Oellerich, Duran Sürün, Anja Derlet, Isabella Haberbosch, Stefan Eimer, Heinz D Osiewacz, Christian Behrends, Christian Münch, Ivan Đikić, Christian H Brandts
Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy. Blood 133 (2) (2018)
Nina Meyer, Svenja Zielke, Jonas B Michaelis, Benedikt Linder, Verena Warnsmann, Stefanie Rakel, Heinz D Osiewacz, Simone Fulda, Michel Mittelbronn, Christian Münch, Christian Behrends, Donat Kögel
AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells. Autophagy 14 (10) (2018)
Koji Yamano, Chunxin Wang, Shireen A Sarraf, Christian Münch, Reika Kikuchi, Nobuo N Noda, Yohei Hizukuri, Masato T Kanemaki, J Wade Harper, Keiji Tanaka, Noriyuki Matsuda, Richard J Youle
Endosomal Rab cycles regulate Parkin-mediated mitophagy. eLife 7 (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christian Münch