Colin G Nichols (Colin Nichols, C G Nichols)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 62

Top Topics

Molecular Dynamics Simulations

Intellectual Disability

Acute Heart Failure

Top Venues

The Journal of general physiology

Nature communications

Function (Oxford, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Jian Gao, Athina Ververi, Ellen Thompson, Rob Tryon, Alexandros Sotiriadis, Fotios Rouvalis, Dorothy K Grange, Christos Giannios, Colin G Nichols
A novel ABCC9 variant in a Greek family with Cantu syndrome affecting multiple generations highlights the functional role of the SUR2B NBD1. American journal of medical genetics. Part A (2024)
Alex Hanson, Conor McClenaghan, Kuo-Chan Weng, Sarah Colijn, Amber N Stratman, Carmen M Halabi, Dorothy K Grange, Jonathan R Silva, Colin G Nichols
Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations. Function (Oxford, England) (2024)
Alex Hanson, Conor McClenaghan, Kuo-Chan Weng, Sarah Colijn, Amber N Stratman, Carmen M Halabi, Dorothy K Grange, Jonathan R Silva, Colin G Nichols
Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations. Function (Oxford, England) (2024)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Michael J Davis, Jorge A Castorena-Gonzalez, Hae Jin Kim, Min Li, Maria Remedi, Colin G Nichols
Lymphatic contractile dysfunction in mouse models of Cantú Syndrome with K ATP channel gain-of-function. Function (Oxford, England) 4 (3) (2023)
Maria S Remedi, Colin G Nichols
Glucokinase Inhibition: A Novel Treatment for Diabetes? Diabetes 72 (2) (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Maria S Remedi, Colin G Nichols
Glucokinase Inhibition: A Novel Treatment for Diabetes? Diabetes 72 (2) (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, Colin G Nichols
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters. Nature communications 14 (1) (2023)
Grigory Maksaev, Michael Bründl-Jirout, Anna Stary-Weinzinger, Eva-Maria Zangerl-Plessl, Sun-Joo Lee, Colin G Nichols
Subunit gating resulting from individual protonation events in Kir2 channels. Research square (2023)
Grigory Maksaev, Michael Bründl-Jirout, Anna Stary-Weinzinger, Eva-Maria Zangerl-Plessl, Sun-Joo Lee, Colin G Nichols
Subunit gating resulting from individual protonation events in Kir2 channels. Nature communications 14 (1) (2023)
Grigory Maksaev, Peng Yuan, Colin G Nichols
Blockade of TRPV channels by intracellular spermine. The Journal of general physiology 155 (5) (2023)
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Oxidation Driven Reversal of PIP 2 -dependent Gating in GIRK2 Channels. Function (Oxford, England) 4 (3) (2023)
Maria S Remedi, Colin G Nichols
Glucokinase Inhibition: A Novel Treatment for Diabetes? Diabetes 72 (2) (2023)
Conor McClenaghan, Maya A Mukadam, Jacob Roeglin, Robert C Tryon, Manfred Grabner, Anamika Dayal, Gretchen A Meyer, Colin G Nichols
Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS. EMBO molecular medicine (2023)
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Oxidation Driven Reversal of PIP 2 -dependent Gating in GIRK2 Channels. Function (Oxford, England) 4 (3) (2023)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Oxidation Driven Reversal of PIP 2 -dependent Gating in GIRK2 Channels. Function (Oxford, England) 4 (3) (2023)
Grigory Maksaev, Peng Yuan, Colin G Nichols
Blockade of TRPV channels by intracellular spermine. The Journal of general physiology 155 (5) (2023)
Jian Gao, Conor G McClenaghan, Kenneth Matreyek, Dorothy K Grange, Colin G Nichols
Rapid characterization of the functional and pharmacological consequences of Cantú syndrome K ATP channel mutations in intact cells . The Journal of pharmacology and experimental therapeutics (2023)
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Oxidation Driven Reversal of PIP 2 -dependent Gating in GIRK2 Channels. Function (Oxford, England) 4 (3) (2023)
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Oxidation Driven Reversal of PIP 2 -dependent Gating in GIRK2 Channels. Function (Oxford, England) 4 (3) (2023)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Grigory Maksaev, Peng Yuan, Colin G Nichols
Blockade of TRPV channels by intracellular spermine. The Journal of general physiology 155 (5) (2023)
Neil L Harrison, Geoffrey W Abbott, Conor McClenaghan, Colin G Nichols, David Cabrera Garcia
Endogenous currents in HEK 293 cells are inhibited by memantine. Nature chemical biology (2023)
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. eLife 12 (2023)
Grigory Maksaev, Peng Yuan, Colin G Nichols
Blockade of TRPV channels by intracellular spermine. The Journal of general physiology 155 (5) (2023)
Michael J Davis, Hae Jin Kim, Colin G Nichols
K<sub>ATP</sub> channels in lymphatic function. American journal of physiology. Cell physiology 323 (4) (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association 11 (24) (2022)
Colin G Nichols, Conor McClenaghan
Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies? Function (Oxford, England) 3 (1) (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Colin G Nichols, Nathaniel W York, Maria S Remedi
ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm? Diabetes 71 (3) (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association 11 (24) (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association 11 (24) (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association 11 (24) (2022)
Conor McClenaghan, Colin G Nichols
Kir6.1 and SUR2B in Cantú syndrome. American journal of physiology. Cell physiology 323 (3) (2022)
Nazzareno D'Avanzo, Andrew J Miles, Andrew M Powl, Colin G Nichols, B A Wallace, Andrias O O'Reilly
The T1-tetramerisation domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac sodium channel. FEBS letters 596 (6) (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, Colin G Nichols
A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome. Journal of the American Heart Association 11 (24) (2022)
Jian Gao, Conor McClenaghan, Imke Christiaans, Marielle Alders, Kirsten van Duinen, Mieke M van Haelst, Gijs van Haaften, Colin G Nichols
Lymphedema as first clinical presentation of Cantu Syndrome: reversed phenotyping after identification of gain-of-function variant in ABCC9. European journal of human genetics : EJHG (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Sun-Joo Lee, Colin G Nichols
Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels. The Journal of general physiology 155 (2) (2022)
Soma S Singareddy, Helen I Roessler, Conor McClenaghan, Jen Ikle, Rob Tryon, Gijs van Haaften, Colin G Nichols
ATP-sensitive potassium channels in zebrafish cardiac and vascular smooth muscle. The Journal of physiology (2021)
J Oh, S J Matkovich, Amy E Riek, S M Bindom, J S Shao, R D Head, Ruteja A Barve, M S Sands, Geert Carmeliet, P Osei-Owusu, R H Knutsen, H Zhang, K J Blumer, Colin G Nichols, Robert P Mecham, Á Baldán, Bruno A Benitez, M L Sequeira-Lopez, R A Gomez, Carlos Bernal-Mizrachi
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension. Nature communications 11 (1) (2020)
Michael J Davis, Hae Jin Kim, Scott D Zawieja, Jorge A Castorena-Gonzalez, Peichun Gui, Min Li, Brian T Saunders, Bernd H Zinselmeyer, Gwendalyn J Randolph, Maria S Remedi, Colin G Nichols
Kir6.1-dependent KATP channels in lymphatic smooth muscle and vessel dysfunction in mice with Kir6.1 gain-of-function. The Journal of physiology 598 (15) (2020)
Christopher H Emfinger, Réka Lőrincz, Yixi Wang, Nathaniel W York, Soma S Singareddy, Jennifer M Ikle, Robert C Tryon, Conor McClenaghan, Zeenat A Shyr, Yan Huang, Christopher A Reissaus, Dirk Meyer, David W Piston, Krzysztof Hyrc, Maria S Remedi, Colin G Nichols
Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets. Physiological reports 7 (11) (2020)
Alan Ma, Sunita Gurnasinghani, Edwin P Kirk, Conor McClenaghan, Gautam K Singh, Dorothy K Grange, Chetan Pandit, Yung Zhu, Tony Roscioli, George Elakis, Michael Buckley, Bhavesh Mehta, Philip Roberts, Jonathan Mervis, Andrew Biggin, Colin G Nichols
Glibenclamide treatment in a Cantú syndrome patient with a pathogenic ABCC9 gain-of-function variant: Initial experience. American journal of medical genetics. Part A 179 (8) (2019)
Zeenat A Shyr, Zhiyu Wang, Nathaniel W York, Colin G Nichols, Maria S Remedi
The role of membrane excitability in pancreatic β-cell glucotoxicity. Scientific reports 9 (1) (2019)
Marie F Smeland, Conor McClenaghan, Helen I Roessler, Sanne Savelberg, Geir Åsmund Myge Hansen, Helene Hjellnes, Kjell Arne Arntzen, Kai Ivar Müller, Andreas Rosenberger Dybesland, Theresa Harter, Monica Sala-Rabanal, Chris H Emfinger, Yan Huang, Soma S Singareddy, Jamie Gunn, David F Wozniak, Attila Kovacs, Maarten Massink, Federico Tessadori, Sarah M Kamel, Jeroen Bakkers, Maria S Remedi, Marijke Van Ghelue, Colin G Nichols, Gijs van Haaften
ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9. Nature communications 10 (1) (2019)
Shizhen Wang, Sun-Joo Lee, Grigory Maksaev, Xin Fang, Chong Zuo, Colin G Nichols
Potassium channel selectivity filter dynamics revealed by single-molecule FRET. Nature chemical biology 15 (4) (2019)
Reka Lorincz, Christopher H Emfinger, Andrea Walcher, Michael Giolai, Claudia Krautgasser, Maria S Remedi, Colin G Nichols, Dirk Meyer
In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish embryos. Islets 10 (6) (2018)
Christopher H Emfinger, Alecia Welscher, Zihan Yan, Yixi Wang, Hannah Conway, Jennifer B Moss, Larry G Moss, Maria S Remedi, Colin G Nichols
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells. Royal Society open science 4 (2) (2017)
William F Borschel, Shizhen Wang, Sunjoo Lee, Colin G Nichols
Control of Kir channel gating by cytoplasmic domain interface interactions. The Journal of general physiology 149 (5) (2017)