Research square

Keyphrases

Publications

2024

Jiyue Zhu, De Cheng, Fan Zhang, Kenneth I Porter, Shuwen Wang, Hui Zhang, Christopher J Davis, Gavin Robertson
Humanization of the mouse telomerase gene reset telomeres to human length. Research square (2024)
Marco Capogrosso, Josep-Maria Balaguer, Genis Prat-Ortega, Nikhil Verma, Prakarsh Yadav, Erynn Sorensen, Roberto de Freitas, Scott Ensel, Luigi Borda, Serena Donadio, Lucy Liang, Jonathan Ho, Arianna Damiani, Erinn Grigsby, Daryl Fields, Jorge Gonzalez-Martinez, Peter Gerszten, Douglas Weber, Elvira Pirondini
Supraspinal control of motoneurons after paralysis enabled by spinal cord stimulation. Research square (2024)
Jonathan B Savitz, Soumyabrata Munshi, Ahlam Alarbi, Haixia Zheng, Rayus Kuplicki, Kaiping Burrows, Leandra K Figueroa-Hall, Teresa Victor, Robin Aupperle, Sahib S Khalsa, Martin P Paulus, T Kent Teague
Increased expression of ER stress, inflammasome activation, and mitochondrial biogenesis-related genes in peripheral blood mononuclear cells in major depressive disorder. Research square (2024)
Gillian L Hirst, Thomas O'Keefe, Christina Yau, Emma Iaconetti, Eliza Jeong, Case Brabham, Paul Kim, Joseph McGuire, Ann Griffin, Anne Wallace, Laura J Esserman, Olivier Harismendy
Duration of Endocrine Treatment for DCIS impacts second events: Insights from a large cohort of cases at two academic medical centers. Research square (2024)
Kirkwood E Personius, Pihu Mehrotra, James Jablonski, John Toftegard, Yali Zhang, Shahryar Shahini, Jianmin Wang, Carey Hung, Reilly Ellis, Gabriella Kayal, Nika Rajabian, Song Liu, Kelly Roballo, Susan B Udin, Stelios T Andreadis
Skeletal muscle reprogramming enhances reinnervation after peripheral nerve injury. Research square (2024)
Luke Harper, Olof Strandberg, Nicola Spotorno, Markus Nilsson, Olof Lindberg, Oskar Hansson, Alexander F Santillo
Structural and functional connectivity associations with anterior cingulate sulcal variability. Research square (2024)
Ram Kumar Singh, Richard J Jones, Fazal Shirazi, Li Qin, Jianxuan Zou, Samuel Hong, Hua Wang, Hans C Lee, Krina K Patel, Jie Wan, Rajan Kumar Choudhary, Isere Kuiatse, Andreas Pahl, Robert Z Orlowski
Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models. Research square (2024)
Xiang Xue, Zhaoli Liu, Yanshan Liang, Young-Yon Kwon, Rui Liu, David Martin, Sheng Hui
Glutathione peroxidase 4 suppresses manganese-dependent oxidative stress to reduce colorectal tumorigenesis. Research square (2024)
Masanori Oshi, Kohei Chida, Arya Mariam Roy, Gabriella Kim Mann, Nan An, Li Yan, Itaru Endo, Kazuaki Takabe
Higher Inflammatory Response in Hepatocellular Carcinoma is Associated with Immune Cell Infiltration and a Better Outcome. Research square (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Concepcion Sanchez, Anamika Campeau, Ru Liu-Bryan, Ted Mikuls, James O'Dell, David Gonzalez, Robert Terkeltaub
Sustained xanthine oxidase inhibitor treat to target urate lowering therapy rewires a tight inflammation serum protein interactome. Research square (2024)
Roberta S Dos Reis, Marc C E Wagner, Savannah McKenna, Velpandi Ayyavoo
Neuroinflammation driven by Human Immunodeficiency Virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of Neurogranin in vivo and in vitro. Research square (2024)
Alexandra Pool, Elizabeth Molina Kuna, Amy Anderson-Mellies, Alexandra Kreis, Marcus Marable, Claire Fraley, Daniel Pacheco, Adam L Green
Medical Record Level-Evaluation of Impact of Demographic and Socioeconomic Factors on Pediatric Neuro-Oncology Outcomes at Children's Hospital Colorado. Research square (2024)
Sean M Hartig, Jessica Felix, Pradip Saha, Evelyn de Groot, Lin Tan, Robert Sharp, Elizabeth Anaya, Yafang Li, Holly Quang, Nooshin Saidi, Layla Abushamat, Christie M Ballantyne, Christopher Ian Amos, Philip L Lorenzi, Samuel Klein, Xia Gao
N-acetylaspartate from fat cells regulates postprandial body temperature. Research square (2024)
David Parker, Rebekah Trotti, Jennifer McDowell, Sarah Keedy, Matcheri S Keshavan, Godfrey Pearlson, Elliot Gershon, Elena Ivleva, Ling-Yu Huang, Kodiak Sauer, Scot Hill, John Sweeny, Carol A Tamminga, Brett Clementz
Differentiating Biomarker Features and Familial Characteristics of B-SNIP Psychosis Biotypes. Research square (2024)
Yuanhao Sun, Xiangdong Li, Haiyang Liu, Yuqing Li, Jiaofeng Gui, Xiaoyun Zhang, Xiaoping Li, Lu Sun, Congzhi Wang, Jing Li, Mingming Liu, Dongmei Zhang, Jingyi Gao, Xuefeng Kang, Yunxiao Lei, Lin Zhang, Ting Yuan
Predictive Role of Depressive Symptoms on Frailty and its Components in Chinese Middle-Aged and Older Adults: a Longitudinal Analysis. Research square (2024)
Samuel A Bobholz, Alisha Hoefs, Jordyn Hamburger, Allison K Lowman, Aleksandra Winiarz, Savannah R Duenweg, Fitzgerald Kyereme, Jennifer Connelly, Dylan Coss, Max Krucoff, Anjishnu Banerjee, Peter S LaViolette
Radio-pathomic maps of glioblastoma identify phenotypes of non-enhancing tumor infiltration associated with bevacizumab treatment response. Research square (2024)
Weidong Yang, Wenlan Yu, Mark Tingey, Joseph Kelich, Yichen Li, Jinjie Yu, Samuel Junod, Zecheng Jiang, Ian Hansen, Nacef Good
Exploring Cellular Gateways: Unraveling the Secrets of Disordered Proteins within Live Nuclear Pores. Research square (2024)
Zachary W Davis, Alexandria Busch, Christopher Steward, Lyle E Muller, John H Reynolds
Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity. Research square (2024)
Andrew Dakopolos, Emma Condy, Elizabeth Smith, Danielle Harvey, Aaron J Kaat, Jeanine Coleman, Karen Riley, Elizabeth Berry-Kravis, David R Hessl
Developmental Associations between Cognition and Adaptive Behavior in Intellectual and Developmental Disability. Research square (2024)
Hua Lu, Zhihui Tan, Hyunmin Ko, Parnia Naji, Rong Zhu, Jieqiong Wang, Shibo Huang, Yi-Wei Zhang, Shelya X Zeng
Tripartite motif-containing protein 26 promotes colorectal cancer growth by inactivating p53. Research square (2024)
Tamara I Tanner, Ilir Agalliu, Dawn M Wahezi, Tamar B Rubinstein, Carra Registry Investigators
Relationship of ultraviolet light exposure and cutaneous and systemic disease activity in youth with childhood-onset systemic lupus: Results from the Childhood Arthritis and Rheumatology Research Alliance Registry. Research square (2024)
Shraddha Mainali, Gaurav Nepal, Amy Webb, Paolo Fadda, Darya Mirebrahimi, Patrick Nana-Sinkam, Brad Worrall, Daniel Woo, Nicholas Johnson, Mohammad Hamed
MicroRNA Expression Profile in Acute Ischemic Stroke. Research square (2024)
Yan Chen, Bin Liu, Chen Huan, Puguang Xie, Chenzhen Du, Shunli Rui, Mei Hao, Zixiao Duan, David G Armstrong, Wuquan Deng, Xiaoqiu Xiao
Comparison of bacterial species and clinical outcomes in patients with diabetic hand infection in tropical and nontropical regions. Research square (2024)
Sven Koehler, Julian Kuhm, Tyler Huffaker, Daniel Young, Animesh Tandon, Florian Andre, Norbert Frey, Gerald Greil, Tarique Hussain, Sandy Engelhardt
Artificial Intelligence to derive aligned strain in cine CMR to detect patients with myocardial fibrosis: an open and scrutinizable approach. Research square (2024)
Bryan Kennedy, Sarala N Malladi, Roger Bh Tootell, Shahin Nasr
A previously undescribed scene-selective site is the key to encoding ego-motion in naturalistic environments. Research square (2024)
Adwoa K A Afrane, Yakubu Alhassan, Linda Eva Amoah, Mame Yaa Nyarko, Adolphina Addo-Lartey, Elijah Paintsil, Kwasi Torpey
Asymptomatic malaria parasitaemia and virological non-suppression among children living with HIV in Accra, Ghana: a cross-sectional study. Research square (2024)
Matthew Halvorsen, Elles de Schipper, Julia Boberg, Nora I Strom, Kristen Hagen, Kerstin Lindblad-Toh, Elinor K Karlsson, Nancy Pedersen, Cynthia M Bulik, Bengt Fundín, Mikael Landén, Gerd Kvale, Bjarne Hansen, Jan Haavik, Manuel Mattheisen, Christian P Rück, David Mataix-Cols, James J Crowley
A Burden of Rare Copy Number Variants in Obsessive-Compulsive Disorder. Research square (2024)
Mala R Ananth, John D Gardus, Chuan Huang, Nikhil Palekar, Mark Slifstein, Laszlo Záborszky, Ramin V Parsey, David A Talmage, Christine DeLorenzo, Lorna W Role
Loss of septal cholinergic input to lateral entorhinal cortex is an early indicator of cognitive impairment. Research square (2024)
Shuhui Wang, Kun Wang, Kangkang Song, Pengfei Li, Dongying Li, Yajie Sun, Ye Mei, Chen Xu, Maofu Liao
Structures of the essential efflux pump EfpA from Mycobacterium tuberculosis reveal the mechanisms of substrate transport and small-molecule inhibition. Research square (2024)
Nicolas Grillet, Pei Wang, Katharine Miller, Enqi He, Siddhant Dhawan, Christopher Cunningham
LOXHD1 is indispensable for coupling auditory mechanosensitive channels to the site of force transmission. Research square (2024)
Debora S Marks, Rose Orenbuch, Aaron Kollasch, Hansen Spinner, Courtney Shearer, Thomas A Hopf, Dinko Franceschi, Mafalda Dias, Jonathan Frazer
Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders. Research square (2024)
Yanchen Zhang, Madeline Larson, Mark G Ehrhart, Kevin King, Aaron R Lyon, Jill Locke, Clayton Cook
Inter-Organizational Alignment and Implementation Outcomes in Integrated Mental Healthcare for Children and Adolescents: A Cross-Sectional Observational Study. Research square (2024)
Lewis Zhichang Shi, Hongxing Shen, Logan Mullen, Oluwagbemiga Ojo, Chuan Xing, Abdelrahman Yassin, Zach Lewis, James Bonner
HIF1α-glycolysis engages activation-induced cell death to drive IFN-γ induction in hypoxic T cells. Research square (2024)
Shannon Ruble, Cassandra Kramer, Lexe West, Karissa Payne, Greg Erickson, Alyssa Scott, Maria M Diehl
Active avoidance under social conditions recruits the anterior cingulate cortex in male and female rats. Research square (2024)
Zening Fu, Jing Sui, Armin Iraji, Jingyu Liu, Vince Calhoun
Cognitive and Psychiatric Relevance of Dynamic Functional Connectivity States in a Large (N>10,000) Children Population. Research square (2024)
Chengjie Xiong, Suzanne Schindler, Jingqin R Luo, John Morris, Randell J Bateman, David M Holtzman, Cruchaga Carlos, Ganesh Babulal, Rachel Henson, Tammie L S Benzinger, Quoc Bui, Folasade Agboola, Elizabeth Grant, Emily Gremminger, Krista Moulder, David Geldmacher, Olivio Clay, Erik D Roberson, Charles Murchison, David Wolk, Leslie Shaw
Baseline levels and longitudinal rates of change in plasma Aβ42/40 among self-identified Black/African American and White individuals. Research square (2024)
Konstantinos Konstantopoulos, Avery Tran, Emily Wisniewski, Panagiotis Mistriotis, Konstantin Stoletov, Maria Parlani, Alice Amitrano, Brent Ifemembi, Se Jong Lee, Kaustav Bera, Yuqi Zhang, Soontorn Tuntithavornwat, Alexandros Afthinos, Alexander Kiepas, John Jamieson, Yi Zuo, Daniel Roy Sadek Habib, Pei Hsun Wu, Stuart Martin, Sharon Gerecht, Luo Gu, John D Lewis, Petr Kalab, Peter Friedl
Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion. Research square (2024)
Hisashi Tanaka, Michael M Murata, Fumie Igari, Ryan Urbanowicz, Lila Mouakkad, Sungjin Kim, Zijing Chen, Dolores Di Vizio, Edwin M Posadas, Armando Giuliano
A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA. Research square (2024)
Andrew Kalra, Preetham Bachina, Benjamin L Shou, Jaeho Hwang, Meylakh Barshay, Shreyas Kulkarni, Isaac Sears, Carsten Eickhoff, Christian A Bermudez, Daniel Brodie, Corey E Ventetuolo, Bo Soo Kim, Glenn J R Whitman, Adeel Abbasi, Sung-Min Cho
Predicting Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation Patients with Tree-Based Machine Learning: Analysis of the Extracorporeal Life Support Organization Registry. Research square (2024)
James A Swartz, Peipei Zhao, Ross Jacobucci, Dennis Watson, Mary Ellen Mackesy-Amiti, Dana Franceschini, A David Jimenez
Associations among Drug Acquisition and Use Behaviors, Psychosocial Attributes, and Opioid-Involved Overdoses: A SEM Analysis. Research square (2024)
Elias Oxman, Huili Li, Hong-Yan Wang, Irene Zohn
Identification and Functional Analysis of Rare HECTD1 Missense Variants in Human Neural Tube Defects. Research square (2024)
Natalie May Zahr, Adolf Pfefferbaum
Serum albumin and white matter hyperintensities. Research square (2024)
Michele Fornaro, Claudio Caiazza, Martina Billeci, Michael Berk, Wolfgang Marx, Vicent Balanzá-Martínez, Michele De Prisco, Rosanna Pezone, Giuseppe De Simone, Niccolo' Solini, Felice Iasevoli, Fabrice Berna, Guillaume Fond, Laurent Boyer, Andre Fèrrer Carvalho, Elena Dragioti, Jess G Fiedorowicz, Andrea de Bartolomeis, Christoph U Correll, Marco Solmi
Nutraceuticals and phytoceuticals in the treatment of schizophrenia: a systematic review and network meta-analysis. Research square (2024)
Juliet N Sekandi, Trang Quach, Ronald Olum, Damalie Nakkonde, Leila Farist, Rochelle Obiekwe, Sarah Zalwango, Esther Buregyeya
Stigma and Associated Sex Disparities Among Patients with Tuberculosis in Uganda: A Cross-Sectional Study. Research square (2024)
Bruce K Krueger, Susan Dorsey, Evelina Mocci, Malcolm Lane
Rapid effects of valproic acid on the fetal brain transcriptome: Implications for brain development and autism. Research square (2024)
Ling Qi, Hancheng Mao, Geun Hyang Kim
SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity. Research square (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis O'Neil, Ching Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Research square (2024)
Oliva Starich, Jared M Rieck, Wyatt J Tarter, Camille J Hochheimer, Vijaya Knight, Jordan K Abbott
Composition of the CD27+ Memory-B-Cell Compartment Delineates Immunoglobulin Deficiency Endotypes. Research square (2024)
Nikolaos Mellios, Grigorios Papageorgiou, Victor Gorgievski, Gabriella Maxson, Megan Hernandez, Madison Otero, Michael Varangis, Michela Dell'Orco, Nora I Perrone-Bizzozero, Eleni Tzavara
Regulation of neuronal circHomer1 biogenesis by PKA/CREB/ERK-mediated pathways and effects of glutamate and dopamine receptor blockade. Research square (2024)