Research square

Keyphrases

Publications

2023

Tiffany L Carson, Doratha A Byrd, Kristen S Smith, Daniel Carter, Michael Abaskaron, Rebecca B Little, Sh'Nese Townsend Holmes, William J van Der Pol, Elliot J Lefkowitz, Casey D Morrow, Andrew D Fruge, Maria Gomez
A case-control study of the association between the gut microbiota and colorectal cancer: exploring the roles of diet, stress, and race. Research square (2023)
Panos Arvanitis, Alexis Hope Lerner, Kendra Vieira, Nouf Almaghlouth, Dimitrios Farmakiotis
Outpatient anti-spike monoclonal antibody administration is associated with decreased morbidity and mortality among patients with cancer and COVID-19. Research square (2023)
Ramya Undamatla, Olayemi G Fagunloye, Jeffrey Chen, Lia R Edmunds, Anjana Murali, Amanda Mills, Bingxian Xie, Martha M Pangburn, Ian Sipula, Gregory Gibson, Claudette St Croix, Michael J Jurczak
Reduced hepatocyte mitophagy is an early feature of NAFLD pathogenesis and hastens the onset of steatosis, inflammation and fibrosis. Research square (2023)
Paige M Porrett, Matthew D Cheung, Rebecca Asiimwe, Elise Erman, Christopher Fucile, Shanrun Liu, Chiao-Wang Sun, Vidya Hanumanthu, Harish Pal, Emma Wright, Gelare Ghajar-Rahimi, Daniel Epstein, Babak J Orandi, Vineeta Kumar, Douglas Anderson, Morgan Greene, Markayla Bell, Stefani Yates, Kyle Moore, Jennifer Lafontaine, John Killian, Gavin Baker, Jackson Perry, Rhiannon Reed, Shawn Little, Alexander Rosenberg, James George, Jayme Locke
Spatiotemporal immune atlas of the first clinical-grade, gene-edited pig-to-human kidney xenotransplant. Research square (2023)
William Walters, Catherine Ley, Trevor J Hastie, Ruth Ley, Julie Parsonnet
Use of a modified Michaelis-Menten equation to estimate growth from birth to 3 years in healthy full term babies. Research square (2023)
Michael Harr, Andrew Lavik, Karen McColl, Fei Zhong, Ben Haberer, Khadijah Aldabbagh, Vivien Yee, Clark W Distelhorst
A novel peptide that disrupts the Lck-IP3R protein-protein interaction induces widespread cell death in leukemia and lymphoma. Research square (2023)
Harry K W Kim, Chi Ma, Minsung Park, Felipe Monte, Vishal Gokani, Olumide Aruwajoye, Yinshi Ren, Xiaohua Liu
Local Administration of Bone Morphogenetic Protein-2 Using a Hydrogel Carrier for Robust Bone Regeneration in a Large Animal Model of Legg-Calvé-Perthes disease. Research square (2023)
Michelle Sophie Keller, Nabeel Qureshi, Elaine Albertson, Joshua Pevnick, Nicole Brandt, Alex Bui, Catherine A Sarkisian
Comparing risk prediction models aimed at predicting hospitalizations for adverse drug events in community dwelling older adults: a protocol paper. Research square (2023)
Nguyen H Tran, Yahya Almodallal, Mashal Batheja, Nicole Martin, Jennifer Le-Rademacher, Jennifer Ridgeway, Irene G Sia, Aminah Jatoi
Social Determinants of Health: A Need for Evidence-Based Guidelines on How to Capture Data on Underserved Patients. Research square (2023)
James Chen, Alice Fruhauf, Catherine Fan, Jackeline Ponce, Beatrix Ueberheide, Gira Bhabha, Damian C Ekiert
Structure of an endogenous mycobacterial MCE lipid transporter. Research square (2023)
Pamela Leland, Dhiraj Kumar, Sridhar Nimaggada, Steven R Bauer, Raj K Puri, Bharat H Joshi
Characterization of Chimeric Antigen Receptor Modified T Cells Expressing scFv-IL-13Rα2 after Radiolabeling with 89Zirconium Oxine for PET Imaging. Research square (2023)
Alyssa Davis, Alyson L Dickson, Laura L Daniel, Puran Nepal, Jacy Zanussi, Tyne W Miller-Fleming, Peter S Straub, Wei-Qi Wei, Ge Liu, Nancy J Cox, Adriana M Hung, QiPing Feng, C Michael Stein, Cecilia P Chung
Association Between Genetically Predicted Expression of TPMT and Azathioprine Adverse Events. Research square (2023)
Arun J Sanyal, Sudha Shankar, Katherine Yates, James Bolognese, Erica Daly, Clayton Dehn, Brent A Neuschwander-Tetri, Kris Kowdley, Raj Vuppalanchi, Cynthia A Behling, James Tonascia, Anthony Samir, Claude B Sirlin, Sarah Sherlock, Kathryn Fowler, Helen Heymann, Tania Kamphaus, Stephen Caldwell, Roberto A Calle
The Nimble Stage 1 Study Validates Diagnostic Circulating Biomarkers for Nonalcoholic Steatohepatitis. Research square (2023)
Mingming Wang, Junfeng Wang, Yuzhen Wang, Manikanda Raja, Gourab Gupta, Xiangxiang Hu, Shanshan Shi, Hexin Chen, Daping Fan, Peisheng Xu
Trim-Away in adult animals through Nano-ERASER and its application in cancer therapy. Research square (2023)
Meng Zhang, César-Díaz Celis, Jianfang Liu, Carlos J Bustamante, Gang Gary Ren
Conformational Change of Nucleosome Arrays prior to Phase Separation. Research square (2023)
Bing Xin Song, Laiba Azhar, Grace Ka Yi Koo, Susan Marzolini, Damien Gallagher, Walter Swardfager, Clara Chen, Joycelyn Ba, Nathan Herrmann, Krista Lanctôt
The effect of exercise on blood concentrations of angiogenesis markers in older adults: a systematic review and meta-analysis. Research square (2023)
Chelsea Phillips, Svetlana Stamatovic, Richard Keep, Anuska Andjelkovic
Epigenetics and stroke: role of DNA methylation and effect of aging on blood-brain barrier recovery. Research square (2023)
James A Swartz, Mary Ellen Mackesy-Amiti, A David Jimenez, Lisa D Robison -Taylor, Elizabeth Prete
Feasibility Study of Using Mobile Phone-Based Experience Sampling to Assess Drug Checking by Opioid Street Drug Users. Research square (2023)
Magdalena Matusiak, John W Hickey, Bogdan Luca, Guolan Lu, Lukasz Kidzinski, Shirley Zhu, Deana Colburg, Darci Phillips, Sky Brubaker, Gregory Charville, Jeanne Shen, Garry P Nolan, Aaron M Newman, Robert West, Matt van de Rijn
A spatial map of human macrophage niches reveals context-dependent macrophage functions in colon and breast cancer. Research square (2023)
Ignacio Emanuel Scarinci, Mauro Valente, Pedro Pérez
A Machine Learning based model for a Dose Point Kernel calculation. Research square (2023)
Riccardo Fodde, Mathijs P Verhagen, Rosalie Joosten, Mark Schmitt, Andrea Sacchetti, Jiahn Choi, Niko Välimäki, Lauri A Aaltonen, Leonard Augenlicht
Paneth cells as the origin of intestinal cancer in the context of inflammation. Research square (2023)
Jeremy A Balch, Tyler J Loftus, Philip A Efron, Alicia M Mohr, Gilbert R Upchurch, R Stephen Smith
Survival and neurologic outcomes following aortic occlusion for trauma and hemorrhagic shock in a hybrid operating room. Research square (2023)
Cale A Jacobs, Robert C Schenck, Leorrie A Watson, Caitlin E W Conley, Darren L Johnson, Austin V Stone, Christian Lattermann, Dustin L Richter
Synovial Fluid Inflammatory Profiles did not Differ between Isolated Anterior Cruciate Ligament and Multi-ligament Knee Injuries. Research square (2023)
Martin N Kaddumukasa, Mark Kaddumukasa, Elly Katabira, Nelson Sewankambo, Lillian D Namujju, Larry B Goldstein
Prevalence and Predictors of Post-stroke Cognitive Impairment among Stroke Survivors in Uganda. Research square (2023)
David Hou, Brandyn Castro, Mark Dapash, Andrew Zolp, Joshua Katz, Víctor Arrieta, Jana Biermann, Johannes C Melms, Jan Kueckelhaus, Jasim Benotmane, Mark Youngblood, Aida Rashidi, Leah Billingham, Crismita Dmello, Gustavo Vazquez-Cervantes, Aurora Lopez-Rosas, Yu Han, Ronit Patel, Tzu-Yi Chia, Lu Sun, Robert M Prins, Benjamin Izar, Deiter Henrik Heiland, Peng Zhang, Adam M Sonabend, Jason M Miska, Maciej Lesniak, Junfei Zhao, Catalina Lee-Chang
B-cells Drive Response to PD-1 Blockade in Glioblastoma Upon Neutralization of TGFβ-mediated Immunosuppression. Research square (2023)
Alexander Gusev, Intae Moon, Jaclyn LoPiccolo, Sylvan Baca, Lynette M Sholl, Kenneth L Kehl, Michael Hassett, David R Liu, Deborah Schrag
Utilizing Electronic Health Records (EHR) and Tumor Panel Sequencing to Demystify Prognosis of Cancer of Unknown Primary (CUP) patients. Research square (2023)
Sonia Jangra, Jeffrey Landers, Gabriel Laghlali, Raveen Rathnasinghe, Jessica J O'Konek, Katarzyna Janczak, Adolfo García-Sastre, James Baker, Michael Schotsaert, Pamela T Wong
A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice. Research square (2023)
Supaporn Wacharapluesadee, Piyapha Hirunpatrawong, Sininat Petcharat, Pattama Torvorapanit, Anusara Jitsatja, Nattakarn Thippamom, Sasiprapa Ninwattana, Chanchanit Phanlop, Rome Buathong, Ratanaporn Tangwangvivat, Chonticha Klungthong, Piyawan Chinnawirotpisan, Taweewun Hunsawong, Krairerk Suthum, Suparerk Komolsiri, Anthony R Jones, Stefan Fernandez, Opass Putcharoen
Simultaneous Detection of Omicron and Other SARS-CoV-2 Variants by Multiplex PCR MassARRAY Technology. Research square (2023)
Siva Venkadesh, Anthony Santarelli, Tyler Boesen, Hong-Wei Dong, Giorgio A Ascoli
Combinatorial quantification of distinct neural projections from retrograde tracing. Research square (2023)
Shinya Imada, Heaji Shin, Saleh Khawaled, Sven Meckelmann, Charles Whittaker, Renan Correa, Dikshant Pradhan, Gizem Calibasi, Luiza Nascentes Nascentes, Gabriele Allies, Pia Wittenhofer, Oliver J Schmitz, Jatin Roper, Marco Vinolo, Chia-Wei Cheng, Alpaslan Tasdogan, Ömer H Yilmaz
Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis. Research square (2023)
Jimmy Zhang, Luo Song, Kwun Chan, Zachary Miller, Kuan-Lin Huang
Predictive Models and Features of Patient Mortality across Dementia Types. Research square (2023)
Hongxin Dong, Daniel Fisher, Jeffrey Dunn, Rachel Keszycki, Guadalupe Rodriguez, David Bennett, Robert Wilson
Unique Transcriptional Signatures Correlate with Behavioral and Psychological Symptom Domains in Alzheimer's Disease. Research square (2023)
Sharon L Campbell, Venkat Chirasani, Mohammad Khan, Juilee Malavade, Nikolay Dokholyan, Brenton Hoffman
Elucidation of the Molecular Basis and Cellular Functions of Vinculin-Actin Directional Catch Bonding. Research square (2023)
Mark Philips, Antonio García-España
Origin and evolution of RAS oncoprotein membrane targeting. Research square (2023)
Grace Scheidemantle, Likun Duan, Mareca Lodge, Magdalina J Cummings, Dalton Hilovsky, Eva Pham, Xiaoqiu Wang, Arion Kennedy, Xiaojing Liu
Data-dependent and -independent acquisition lipidomics analysis reveals the tissue-dependent effect of metformin on lipid metabolism. Research square (2023)
Roozbeh Jafari, Kaan Sel, Amirmohammad Mohammadi, Roderic I Pettigrew
Physics-Informed Neural Networks for Modeling Physiological Time Series: A Case Study with Continuous Blood Pressure. Research square (2023)
Jun Yup Lee, Dylan Harney, John Kwok, Mark Larance, Anthony Simon Don
The major TMEM106B dementia risk allele affects TMEM106B protein levels and myelin lipid homeostasis in the ageing human hippocampus. Research square (2023)
Shizhong Ke, Fabin Dang, Lin Wang, Jia-Yun Chen, Mandar Naik, Abhishek Thavamani, Yansheng Liu, Wenxue Li, Nami Kim, Nandita Naik, Huaxiu Sui, Wei Tang, Chenxi Qiu, Kazuhiro Koikawa, Xiaodong Wang, Felipe Batalini, John Gerard Clohessy, Yujing Heng, Galit Lahav, Nathanael S Gray, Xiao Zhen Zhou, null Wei, Gerburg M Wulf, Kun Ping Lu
Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability. Research square (2023)
Jun Yi Wang, Gerard J Sonico, Maria Jimena Salcedo-Arellano, Randi J Hagerman, Verónica Martínez-Cerdeño
A postmortem MRI study of cerebrovascular disease and iron content at end-stage of fragile X-associated tremor/ataxia syndrome. Research square (2023)
Shadhmer Demehri, Jong Ho Park, Mahsa Mortaja, Heehwa Son, Marjan Azin, Jun Wang, Michael Collier, Anna Mandinova, Yevgeniy R Semenov, Mari A Mino-Kenudson
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Research square (2023)
Yingying Jiao, Weiyi Li, Xiaofang Jia, Zhihong Wang, Hui-Jun Wang, Bing Zhang, Hong-Ru Jiang, Gangqiang Ding
Association between regional dietary patterns and cardiovascular health status among elderly in China. Research square (2023)
Rudi Fasan, Satyajit Roy, David Vargas, Pengchen Ma, Arkajyoti Sengupta, Kendall N Houk
Stereoselective Construction of β-, γ-, and δ-Lactam Rings via Enzymatic C-H Amidation. Research square (2023)
Willie Njoroge, Rachel Maina, Frank Elena, Lukoye Atwoli, Zhenke Wu, Anthony Ngugi, Srijan Sen, Jian Wang, Stephen Wong, Jessica Baker, Eileen Haus, Linda Khakali, Andrew Aballa, James Orwa, Moses Nyongesa, Zul Merali, Karim Akbar, Amina Abubakar
Use of Mobile Technology to Identify Behavioral Mechanisms Linked to Mental Health Outcomes in Kenya: Protocol for Development and Validation of a Predictive Model. Research square (2023)
Lyle G Best, Marcia O'Leary, Rae O'Leary, Wendy Lawrence, Dara G Torgerson
Return of Participants' Incidental Genetic Research Findings: Experience from a Case-Control Study of Asthma in an American Indian Community. Research square (2023)
Julia J Lund, Elizabeth Tomsich, Julia P Schleimer, Veronica A Pear
Changes in self-harm and suicide in California from 2017-2021: a population-based study. Research square (2023)
Rosana Wiscovitch-Russo, Elsa D Ibáñez-Prada, Cristian C Serrano-Mayorga, Benjamin L Sievers, Maeve A Engelbride, Surya Padmanabhan, Gene S Tan, Sanjay Vashee, Ingrid G Bustos, Carlos Pachecho, Lina Mendez, Peter H Dube, Harinder Singh, Luis Felipe Reyes, Norberto Gonzalez-Juarbe
Necroptosis Drives Major Adverse Cardiovascular Events During Severe COVID-19. Research square (2023)
Nan Bai, Yusuf Adeshina, Igor Bychkov, Yan Xia, Ragul Gowthaman, Sven A Miller, Abhishek Gupta, David K Johnson, Lan Lan, Erica A Golemis, Peter Makhov, Liang Xu, Manoj M Pillai, Yanis Boumber, John Karanicolas
Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry. Research square (2023)
Christian Sinnott, Peter Hausamann, Paul R MacNeilage
Natural statistics of human head orientation constrain models of vestibular processing. Research square (2023)
Martha Namusobya, Felix Bongomin, John Mukisa, Charles Batte, William Kane Olwit, Joshua Rhein, Christine Sekaggya-Wiltshire, Shailendra Prasad
The Impact of Chronic Pulmonary Aspergillosis Co-infection on the Health-Related Quality of Life of Patients with Pulmonary Tuberculosis in Uganda. Research square (2023)
Stephanie L Baringer, Kondaiah Palsa, Ian A Simpson, James R Connor
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier. Research square (2023)