D Sean Froese

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Topics

Induced Pluripotent Stem Cells

Top Venues

Journal of inherited metabolic disease

Nature communications

Nature metabolism

This page only lists publications with an associated author ORCID identifier.

Publications

Linnea K M Blomgren, Melanie Huber, Sabrina R Mackinnon, Céline Bürer, Arnaud Basle, Wyatt W Yue, D Sean Froese, Thomas J McCorvie
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nature communications 15 (1) (2024)
Linnea K M Blomgren, Melanie Huber, Sabrina R Mackinnon, Céline Bürer, Arnaud Basle, Wyatt W Yue, D Sean Froese, Thomas J McCorvie
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nature communications 15 (1) (2024)
Linnea K M Blomgren, Melanie Huber, Sabrina R Mackinnon, Céline Bürer, Arnaud Basle, Wyatt W Yue, D Sean Froese, Thomas J McCorvie
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nature communications 15 (1) (2024)
Linnea K M Blomgren, Melanie Huber, Sabrina R Mackinnon, Céline Bürer, Arnaud Basle, Wyatt W Yue, D Sean Froese, Thomas J McCorvie
Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nature communications 15 (1) (2024)
Patrick Forny, Ximena Bonilla, David Lamparter, Wenguang Shao, Tanja Plessl, Caroline Frei, Anna Bingisser, Sandra Goetze, Audrey van Drogen, Keith Harshman, Patrick G A Pedrioli, Cedric Howald, Martin Poms, Florian Traversi, Céline Bürer, Sarah Cherkaoui, Raphael J Morscher, Luke Simmons, Merima Forny, Ioannis Xenarios, Ruedi Aebersold, Nicola Zamboni, Gunnar Rätsch, Emmanouil T Dermitzakis, Bernd Wollscheid, Matthias R Baumgartner, D Sean Froese
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature metabolism 5 (1) (2023)
Thomas J McCorvie, Douglas Ferreira, Wyatt W Yue, D Sean Froese
The complex machinery of human cobalamin metabolism. Journal of inherited metabolic disease (2023)
Patrick Forny, Ximena Bonilla, David Lamparter, Wenguang Shao, Tanja Plessl, Caroline Frei, Anna Bingisser, Sandra Goetze, Audrey van Drogen, Keith Harshman, Patrick G A Pedrioli, Cedric Howald, Martin Poms, Florian Traversi, Céline Bürer, Sarah Cherkaoui, Raphael J Morscher, Luke Simmons, Merima Forny, Ioannis Xenarios, Ruedi Aebersold, Nicola Zamboni, Gunnar Rätsch, Emmanouil T Dermitzakis, Bernd Wollscheid, Matthias R Baumgartner, D Sean Froese
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature metabolism 5 (1) (2023)
Marie Lucienne, Raffaele Gerlini, Birgit Rathkolb, Julia Calzada-Wack, Patrick Forny, Stephan Wueest, Andres Kaech, Florian Traversi, Merima Forny, Céline Bürer, Antonio Aguilar-Pimentel, Martin Irmler, Johannes Beckers, Sven Sauer, Stefan Kölker, Joseph P Dewulf, Guido T Bommer, Daniel Hoces, Valerie Gailus-Durner, Helmut Fuchs, Jan Rozman, D Sean Froese, Matthias R Baumgartner, Martin Hrabě de Angelis
Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria. Human molecular genetics (2023)
Patrick Forny, Ximena Bonilla, David Lamparter, Wenguang Shao, Tanja Plessl, Caroline Frei, Anna Bingisser, Sandra Goetze, Audrey van Drogen, Keith Harshman, Patrick G A Pedrioli, Cedric Howald, Martin Poms, Florian Traversi, Céline Bürer, Sarah Cherkaoui, Raphael J Morscher, Luke Simmons, Merima Forny, Ioannis Xenarios, Ruedi Aebersold, Nicola Zamboni, Gunnar Rätsch, Emmanouil T Dermitzakis, Bernd Wollscheid, Matthias R Baumgartner, D Sean Froese
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature metabolism 5 (1) (2023)
Thomas J McCorvie, Douglas Ferreira, Wyatt W Yue, D Sean Froese
The complex machinery of human cobalamin metabolism. Journal of inherited metabolic disease (2023)
Patrick Forny, Ximena Bonilla, David Lamparter, Wenguang Shao, Tanja Plessl, Caroline Frei, Anna Bingisser, Sandra Goetze, Audrey van Drogen, Keith Harshman, Patrick G A Pedrioli, Cedric Howald, Martin Poms, Florian Traversi, Céline Bürer, Sarah Cherkaoui, Raphael J Morscher, Luke Simmons, Merima Forny, Ioannis Xenarios, Ruedi Aebersold, Nicola Zamboni, Gunnar Rätsch, Emmanouil T Dermitzakis, Bernd Wollscheid, Matthias R Baumgartner, D Sean Froese
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature metabolism 5 (1) (2023)
Patrick Forny, Ximena Bonilla, David Lamparter, Wenguang Shao, Tanja Plessl, Caroline Frei, Anna Bingisser, Sandra Goetze, Audrey van Drogen, Keith Harshman, Patrick G A Pedrioli, Cedric Howald, Martin Poms, Florian Traversi, Céline Bürer, Sarah Cherkaoui, Raphael J Morscher, Luke Simmons, Merima Forny, Ioannis Xenarios, Ruedi Aebersold, Nicola Zamboni, Gunnar Rätsch, Emmanouil T Dermitzakis, Bernd Wollscheid, Matthias R Baumgartner, D Sean Froese
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature metabolism 5 (1) (2023)
Thomas J McCorvie, Douglas Ferreira, Wyatt W Yue, D Sean Froese
The complex machinery of human cobalamin metabolism. Journal of inherited metabolic disease (2023)
Thomas J McCorvie, Paula M Loria, Meihua Tu, Seungil Han, Leela Shrestha, D Sean Froese, Igor M Ferreira, Allison P Berg, Wyatt W Yue
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate. Nature structural & molecular biology 29 (7) (2022)
Charlotte Ramon, Florian Traversi, Céline Bürer, D Sean Froese, Joerg Stelling
Cellular and computational models reveal environmental and metabolic interactions in MMUT-type methylmalonic aciduria. Journal of inherited metabolic disease (2022)
Patrick Forny, Tanja Plessl, Caroline Frei, Celine Bürer, D Sean Froese, Matthias R Baumgartner
Spectrum and characterization of bi-allelic variants in MMAB causing cblB-type methylmalonic aciduria. Human genetics (2021)
Marie Lucienne, Déborah Mathis, Nathan Perkins, Ralph Fingerhut, Matthias R Baumgartner, D Sean Froese
Decrease of disease-related metabolites upon fasting in a hemizygous knock-in mouse model (Mut-ko/ki) of methylmalonic aciduria. JIMD reports 58 (1) (2020)
D Sean Froese, Brian Fowler, Matthias R Baumgartner
Vitamin B12 , folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation. Journal of inherited metabolic disease 42 (4) (2019)
D Sean Froese, Jolanta Kopec, Elzbieta Rembeza, Gustavo Arruda Bezerra, Anselm Erich Oberholzer, Terttu Suormala, Seraina Lutz, Rod Chalk, Oktawia Borkowska, Matthias R Baumgartner, Wyatt W Yue
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition. Nature communications 9 (1) (2018)
Tanja Plessl, Céline Bürer, Seraina Lutz, Wyatt W Yue, Matthias R Baumgartner, D Sean Froese
Protein destabilization and loss of protein-protein interaction are fundamental mechanisms in cblA-type methylmalonic aciduria. Human mutation 38 (8) (2017)