Darren G Monckton (Darren Monckton)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 34

Top Venues

European journal of human genetics : EJHG

Brain communications

Proceedings of the National Academy of Sciences of the United States of America

Neurology. Genetics

University of Glasgow

University of Leicester (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Glasgow Oct 01 1996

United Kingdom

Professor of Human Genetics :: Institute of Molecular, Cell and Systems Biology

Education History

University of Leicester

United Kingdom

PHD :: Department of Genetics

Publications

Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG 32 (7) (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Kyung-Hee Kim, Eun Pyo Hong, Yukyeong Lee, Zachariah L McLean, Emanuela Elezi, Ramee Lee, Seung Kwak, Branduff McAllister, Thomas H Massey, Sergey Lobanov, Peter Holmans, Michael Orth, Marc Ciosi, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG 32 (7) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG 32 (7) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG (2024)
null null, Jong-Min Lee, Zachariah L McLean, Kevin Correia, Jun Wan Shin, Sujin Lee, Jae-Hyun Jang, Yukyeong Lee, Kyung-Hee Kim, Doo Eun Choi, Jeffrey D Long, Diane Lucente, Ihn Sik Seong, Ricardo Mouro Pinto, James V Giordano, Jayalakshmi S Mysore, Jacqueline Siciliano, Emanuela Elezi, Jayla Ruliera, Tammy Gillis, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Anna Gatseva, Marc Ciosi, Vilija Lomeikaite, Hossameldin Loay, Darren G Monckton, Christopher Wills, Thomas H Massey, Lesley Jones, Peter A Holmans, Seung Kwak, Cristina Sampaio, Michael Orth, G Bernhard Landwehrmeyer, Jane S Paulsen, E Ray Dorsey, Richard H Myers
Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease reveal shared and tissue-specific effects. bioRxiv : the preprint server for biology (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Ainara Ruiz de Sabando, Marc Ciosi, Arkaitz Galbete, Sarah A Cumming, null null, Darren G Monckton, María A Ramos-Arroyo
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European journal of human genetics : EJHG 32 (7) (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Eun Pyo Hong, Eliana Marisa Ramos, N Ahmad Aziz, Thomas H Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi, Vilija Lomeikaite, Darren G Monckton, Jeffrey D Long, Diane Lucente, Vanessa C Wheeler, Tammy Gillis, Marcy E MacDonald, Jorge Sequeiros, James F Gusella, Jong-Min Lee
Modification of Huntington's disease by short tandem repeats. Brain communications 6 (2) (2024)
Alysha S Taylor, Dinis Barros, Nastassia Gobet, Thierry Schuepbach, Branduff McAllister, Lorene Aeschbach, Emma L Randall, Evgeniya Trofimenko, Eleanor R Heuchan, Paula Barszcz, Marc Ciosi, Joanne Morgan, Nathaniel J Hafford-Tear, Alice E Davidson, Thomas H Massey, Darren G Monckton, Lesley Jones, Registry Investigators Of The European Huntington's Disease Network, Ioannis Xenarios, Vincent Dion
Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR genomics and bioinformatics 4 (4) (2022)
Ainara Ruiz de Sabando, Edurne Urrutia Lafuente, Arkaitz Galbete, Marc Ciosi, Fermín García Amigot, Virginia García Solaesa, null null, Darren G Monckton, Maria A Ramos-Arroyo
Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease. Human molecular genetics (2022)
Branduff McAllister, Jasmine Donaldson, Caroline S Binda, Sophie Powell, Uroosa Chughtai, Gareth Edwards, Joseph Stone, Sergey V Lobanov, Linda Elliston, Laura-Nadine Schuhmacher, Elliott Rees, Georgina E Menzies, Marc Ciosi, Alastair Maxwell, Michael J Chao, Eun Pyo Hong, Diane Lucente, Vanessa Wheeler, Jong-Min Lee, Marcy E MacDonald, Jeffrey D Long, Elizabeth H Aylward, G Bernhard Landwehrmeyer, Anne E Rosser, null null, Jane S Paulsen, null null, Nigel M Williams, James F Gusella, Darren G Monckton, Nicholas D Allen, Peter A Holmans, Lesley Jones, Thomas H Massey
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature neuroscience 25 (4) (2022)
Stephan Wenninger, Sarah A Cumming, Kristina Gutschmidt, Kees Okkersen, Aura Cecilia Jimenez-Moreno, Ferroudja Daidj, Hanns Lochmüller, Fiona Hogarth, Hans Knoop, Guillaume Bassez, Darren G Monckton, Baziel G M van Engelen, Benedikt Schoser
Associations Between Variant Repeat Interruptions and Clinical Outcomes in Myotonic Dystrophy Type 1. Neurology. Genetics 7 (2) (2021)
Ellen van der Plas, Timothy R Koscik, Vincent A Magnotta, Sarah A Cumming, Darren G Monckton, Laurie Gutmann, Peggy C Nopoulos
Neurocognitive Features of Motor Premanifest Individuals With Myotonic Dystrophy Type 1. Neurology. Genetics 7 (2) (2021)
Erik Landfeldt, Nikoletta Nikolenko, Cecilia Jimenez-Moreno, Sarah A Cumming, Darren G Monckton, Catharina G Faber, Ingemar S J Merkies, Grainne Gorman, Chris Turner, Hanns Lochmüller
Activities of daily living in myotonic dystrophy type 1. Acta neurologica Scandinavica 141 (5) (2020)
Jacob N Miller, Ellen van der Plas, Mark J Hamilton, Timothy R Koscik, Laurie Gutmann, Sarah A Cumming, Darren G Monckton, Peggy C Nopoulos
Variant repeats within the DMPK CTG expansion protect function in myotonic dystrophy type 1. Neurology. Genetics 6 (5) (2020)
Édith Breton, Cécilia Légaré, Gayle Overend, Simon-Pierre Guay, Darren G Monckton, Jean Mathieu, Cynthia Gagnon, Louis Richer, Benjamin Gallais, Luigi Bouchard
DNA methylation at the DMPK gene locus is associated with cognitive functions in myotonic dystrophy type 1. Epigenomics 12 (23) (2020)
Ake T Lu, Pritika Narayan, Matthew J Grant, Peter Langfelder, Nan Wang, Seung Kwak, Hilary Wilkinson, Richard Z Chen, Jian Chen, C Simon Bawden, Skye R Rudiger, Marc Ciosi, Afroditi Chatzi, Alastair Maxwell, Timothy Alexander Hore, Jeff Aaronson, Jim Rosinski, Alicia Preiss, Thomas F Vogt, Giovanni Coppola, Darren G Monckton, Russell G Snell, Xiangdong William Yang, Steve Horvath
DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature communications 11 (1) (2020)
Alfonsina Ballester-Lopez, Emma Koehorst, Ian Linares-Pardo, Judit Núñez-Manchón, Miriam Almendrote, Giuseppe Lucente, Andrea Arbex, Carles Puente, Alejandro Lucia, Darren G Monckton, Sarah A Cumming, Guillem Pintos-Morell, Jaume Coll-Cantí, Alba Ramos-Fransi, Alicia Martínez-Piñeiro, Gisela Nogales-Gadea
Preliminary Findings on CTG Expansion Determination in Different Tissues from Patients with Myotonic Dystrophy Type 1. Genes 11 (11) (2020)
Sarah A Cumming, Aura Cecilia Jimenez-Moreno, Kees Okkersen, Stephan Wenninger, Ferroudja Daidj, Fiona Hogarth, Roberta Littleford, Gráinne Siobhan Gorman, Guillaume Bassez, Benedikt Schoser, Hanns Lochmüller, Baziel G M van Engelen, Darren G Monckton, null null
Genetic determinants of disease severity in the myotonic dystrophy type 1 OPTIMISTIC cohort. Neurology 93 (10) (2019)
Linda Heskamp, Marlies van Nimwegen, Marieke J Ploegmakers, Guillaume Bassez, Jean-Francois Deux, Sarah A Cumming, Darren G Monckton, Baziel G M van Engelen, Arend Heerschap
Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI. Neurology 92 (24) (2019)
Eyleen Corrales, Melissa Vásquez, Baili Zhang, Carolina Santamaría-Ulloa, Patricia Cuenca, Ralf Krahe, Darren G Monckton, Fernando Morales
Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1. PloS one 14 (5) (2019)
Alfonsina Ballester-Lopez, Emma Koehorst, Miriam Almendrote, Alicia Martínez-Piñeiro, Giuseppe Lucente, Ian Linares-Pardo, Judit Núñez-Manchón, Nicolau Guanyabens, Antoni Cano, Alejandro Lucia, Gayle Overend, Sarah A Cumming, Darren G Monckton, Teresa Casadevall, Irina Isern, Josep Sánchez-Ojanguren, Albert Planas, Agustín Rodriguez-Palmero, Laura Monlleó-Neila, Guillem Pintos-Morell, Alba Ramos-Fransi, Jaume Coll-Cantí, Gisela Nogales-Gadea
A DM1 family with interruptions associated with atypical symptoms and late onset but not with a milder phenotype. Human mutation 41 (2) (2019)
Sarah A Cumming, Mark J Hamilton, Yvonne Robb, Helen Gregory, Catherine McWilliam, Anneli Cooper, Berit Adam, Josephine McGhie, Graham Hamilton, Pawel Herzyk, Michael R Tschannen, Elizabeth Worthey, Richard Petty, Bob Ballantyne, null null, Jon Warner, Maria Elena Farrugia, Cheryl Longman, Darren G Monckton
De novo repeat interruptions are associated with reduced somatic instability and mild or absent clinical features in myotonic dystrophy type 1. European journal of human genetics : EJHG 26 (11) (2018)

Darren G Monckton.css-eqlu8i{font-size:small;padding-left:4px;} (Darren Monckton)

Publication Activity (10 Years)

Top Topics

Top Venues

Darren G Monckton (Darren Monckton)