David A Hume

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Venues

Journal of leukocyte biology

Journal of immunology (Baltimore, Md. : 1950)

Proceedings of the National Academy of Sciences of the United States of America

NAR genomics and bioinformatics

University of Queensland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Queensland Jan 01 2018

Australia

Professor :: Mater Research Institute

University Of Edinburgh Jan 01 2007 - Dec 31 2017

United Kingdom

Director :: The Roslin Institute

Publications

Lena Batoon, Sahar Keshvari, Katharine M Irvine, Eileen Ho, Melanie Caruso, Omkar L Patkar, Anuj Sehgal, Susan M Millard, David A Hume, Allison R Pettit
Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer. Journal of leukocyte biology (2024)
David A Hume, Ngari Teakle, Sahar Keshvari, Katharine M Irvine
Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development. Journal of leukocyte biology (2023)
David A Hume, Lena Batoon, Anuj Sehgal, Sahar Keshvari, Katharine M Irvine
CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple. Current osteoporosis reports 20 (6) (2022)
Tom C Freeman, Sebastian Horsewell, Anirudh Patir, Joshua D Harling-Lee, Tim Regan, Barbara Bo-Ju Shih, James G D Prendergast, David A Hume, Tim Angus
Graphia: A platform for the graph-based visualisation and analysis of high dimensional data. PLoS computational biology 18 (7) (2022)
Jennifer Stables, Emma K Green, Anuj Sehgal, Omkar L Patkar, Sahar Keshvari, Isis Taylor, Maisie E Ashcroft, Kathleen Grabert, Evi Wollscheid-Lengeling, Stefan Szymkowiak, Barry W McColl, Antony Adamson, Neil E Humphreys, Werner Mueller, Hana Starobova, Irina Vetter, Sepideh Kiani Shabestari, Matthew M Blurton-Jones, Kim M Summers, Katharine M Irvine, Clare Pridans, David A Hume
A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling. Development (Cambridge, England) 149 (8) (2022)
Kim M Summers, Stephen J Bush, Chunlei Wu, David A Hume
Generation and network analysis of an RNA-seq transcriptional atlas for the rat. NAR genomics and bioinformatics 4 (1) (2022)
Kim N Green, David A Hume
On the utility of CSF1R inhibitors. Proceedings of the National Academy of Sciences of the United States of America 118 (4) (2021)
Sahar Keshvari, Melanie Caruso, Ngari Teakle, Lena Batoon, Anuj Sehgal, Omkar L Patkar, Michelle Ferrari-Cestari, Cameron E Snell, Chen Chen, Alexander J Stevenson, Felicity Mae Davis, Stephen J Bush, Clare Pridans, Kim M Summers, Allison R Pettit, Katharine M Irvine, David A Hume
CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS genetics 17 (6) (2021)
Zofia M Lisowski, Lucas Lefevre, Tim S Mair, Emily L Clark, Neil P H Hudson, David A Hume, R Scott Pirie
Use of quantitative real-time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis of horses undergoing small intestinal resection. Equine veterinary journal 54 (1) (2021)
David A Hume, Melanie Caruso, Sahar Keshvari, Omkar L Patkar, Anuj Sehgal, Stephen J Bush, Kim M Summers, Clare Pridans, Katharine M Irvine
The Mononuclear Phagocyte System of the Rat. Journal of immunology (Baltimore, Md. : 1950) 206 (10) (2021)
Kim M Summers, Stephen J Bush, David A Hume
Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. PLoS biology 18 (10) (2020)
Kathleen Grabert, Anuj Sehgal, Katharine M Irvine, Evi Wollscheid-Lengeling, Derya D Ozdemir, Jennifer Stables, Garry A Luke, Martin D Ryan, Antony D Adamson, Neil E Humphreys, Cheyenne J Sandrock, Rocío Rojo, Veera A Verkasalo, Werner Muller, Peter Hohenstein, Allison R Pettit, Clare Pridans, David A Hume
A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System. Journal of immunology (Baltimore, Md. : 1950) 205 (11) (2020)
Katharine M Irvine, Melanie Caruso, Michelle Ferrari Cestari, Gemma M Davis, Sahar Keshvari, Anuj Sehgal, Clare Pridans, David A Hume
Analysis of the impact of CSF-1 administration in adult rats using a novel Csf1r-mApple reporter gene. Journal of leukocyte biology 107 (2) (2019)
David A Hume, Melanie Caruso, Michelle Ferrari-Cestari, Kim M Summers, Clare Pridans, Katharine M Irvine
Phenotypic impacts of CSF1R deficiencies in humans and model organisms. Journal of leukocyte biology 107 (2) (2019)
David A Hume, Maria W Gutowska-Ding, Carla Garcia-Morales, Adebabay Kebede, Oladeji Bamidele, Adriana Vallejo Trujillo, Almas A Gheyas, Jacqueline Smith
Functional evolution of the colony-stimulating factor 1 receptor (CSF1R) and its ligands in birds. Journal of leukocyte biology 107 (2) (2019)
Tuanjun Hu, Zhiguang Wu, Stephen J Bush, Lucy Freem, Lonneke Vervelde, Kim M Summers, David A Hume, Adam Balic, Pete Kaiser
Characterization of Subpopulations of Chicken Mononuclear Phagocytes That Express TIM4 and CSF1R. Journal of immunology (Baltimore, Md. : 1950) 202 (4) (2019)
V Kartik Chundru, Riccardo E Marioni, James G D Prendergast, Costanza Ludovica Vallerga, Tian Lin, Allan J Beveridge, null null, Jacob Gratten, David A Hume, Ian J Deary, Naomi R Wray, Peter M Visscher, Allan F McRae
Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait. Genetics 212 (3) (2019)
Clare Pridans, Anna Raper, Gemma M Davis, Joana Alves, Kristin A Sauter, Lucas Lefevre, Tim Regan, Stephen Meek, Linda Sutherland, Alison J Thomson, Sara Clohisey Hendry, Stephen J Bush, Rocío Rojo, Zofia M Lisowski, Robert Wallace, Kathleen Grabert, Kyle R Upton, Yi Ting Tsai, Deborah Brown, Lee B Smith, Kim M Summers, Neil A Mabbott, Pedro Piccardo, Michael T Cheeseman, Tom Burdon, David A Hume
Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus. Journal of immunology (Baltimore, Md. : 1950) 201 (9) (2018)

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Publication Activity (10 Years)

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David A Hume