David A Lomas

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 9

Top Venues

EMBO molecular medicine

The FEBS journal

Science advances

Hepatology (Baltimore, Md.)

This page only lists publications with an associated author ORCID identifier.

Publications

Kamila Kamuda, Riccardo Ronzoni, Avik Majumdar, Fiona H X Guan, James A Irving, David A Lomas
A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. The FEBS journal 291 (13) (2024)
Deniz Kent, Soon Seng Ng, Adam M Syanda, Payam Khoshkenar, Riccardo Ronzoni, Chao Zheng Li, Marina Zieger, Cindy Greer, Stephanie Hatch, Joe Segal, Samuel J I Blackford, Yu Ri Im, Vivek Chowdary, Taylor Ismaili, Davide Danovi, Patrick A Lewis, James A Irving, Sunil Sahdeo, David A Lomas, Daniel Ebner, Christian Mueller, Sheikh Tamir Rashid
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors. Hepatology (Baltimore, Md.) (2024)
Kamila Kamuda, Riccardo Ronzoni, Avik Majumdar, Fiona H X Guan, James A Irving, David A Lomas
A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. The FEBS journal (2024)
Marie-Christine Bouton, Margarethe Geiger, William P Sheffield, James A Irving, David A Lomas, Sihong Song, Ritvik S Satyanarayanan, Liqiang Zhang, Grant McFadden, Alexandra R Lucas
The under-appreciated world of the serpin family of serine proteinase inhibitors. EMBO molecular medicine (2023)
Samuele Raccosta, Fabio Librizzi, Alistair M Jagger, Rosina Noto, Vincenzo Martorana, David A Lomas, James A Irving, Mauro Manno
Scaling Concepts in Serpin Polymer Physics. Materials (Basel, Switzerland) 14 (10) (2021)
David A Lomas, James A Irving, Christopher Arico-Muendel, Svetlana Belyanskaya, Andrew Brewster, Murray Brown, Chun-Wa Chung, Hitesh Dave, Alexis Denis, Nerina Dodic, Anthony Dossang, Peter Eddershaw, Diana Klimaszewska, Imran Haq, Duncan S Holmes, Jonathan P Hutchinson, Alistair M Jagger, Toral Jakhria, Emilie Jigorel, John Liddle, Ken Lind, Stefan J Marciniak, Jeff Messer, Margaret Neu, Allison Olszewski, Adriana Ordonez, Riccardo Ronzoni, James Rowedder, Martin Rüdiger, Steve Skinner, Kathrine J Smith, Rebecca Terry, Lionel Trottet, Iain Uings, Steve Wilson, Zhengrong Zhu, Andrew C Pearce
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin. EMBO molecular medicine 13 (3) (2021)
Malin Fromme, Carolin V Schneider, Vitor Pereira, Karim Hamesch, Monica Pons, Matthias Christian Reichert, Federica Benini, Paul Ellis, Katrine H Thorhauge, Mattias Mandorfer, Barbara Burbaum, Vivien Woditsch, Joanna Chorostowska-Wynimko, Jef Verbeek, Frederik Nevens, Joan Genesca, Marc Miravitlles, Alexa Nuñez, Benedikt Schaefer, Heinz Zoller, Sabina Janciauskiene, Nélia Abreu, Luís Jasmins, Rui Gaspar, Rodrigo Liberal, Guilherme Macedo, Ravi Mahadeva, Catarina Gomes, Kai Markus Schneider, Michael Trauner, Aleksander Krag, Bibek Gooptu, Douglas Thorburn, Aileen Marshall, John R Hurst, David A Lomas, Frank Lammert, Nadine T Gaisa, Virginia Clark, William Griffiths, Christian Trautwein, Alice M Turner, Noel G McElvaney, Pavel Strnad
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency. Gut (2021)
Riccardo Ronzoni, Ilaria Ferrarotti, Emanuela D'Acunto, Alice Maria Balderacchi, Stefania Ottaviani, David A Lomas, James A Irving, Elena Miranda, Annamaria Fra
The Importance of N186 in the Alpha-1-Antitrypsin Shutter Region Is Revealed by the Novel Bologna Deficiency Variant. International journal of molecular sciences 22 (11) (2021)
Sarah V Faull, Emma L K Elliston, Bibek Gooptu, Alistair M Jagger, Ibrahim Aldobiyan, Adam Redzej, Magd Badaoui, Nina Heyer-Chauhan, Sheikh Tamir Rashid, Gary M Reynolds, David H Adams, Elena Miranda, Elena V Orlova, James A Irving, David A Lomas
The structural basis for Z α1-antitrypsin polymerization in the liver. Science advances 6 (43) (2020)

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Publication Activity (10 Years)

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David A Lomas