David A Sinclair

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Nature aging

EMBO molecular medicine

Nature communications

Nature biotechnology

Harvard Medical School

University of New South Wales (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School

United States

Professor :: Genetics

Harvard Medical School

United States

Associate Professor :: Pathology

Harvard Medical School

United States

Assistant Professor :: Pathology

Massachusetts Institute of Technology

United States

Postdoctoral Fellow :: Biology

Education History

University of New South Wales

Australia

PHD :: Biochemistry

University of New South Wales

Australia

BSC :: Biochemistry

Publications

Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Lynn-Jee Kim, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Emily R Frost, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Romanthi Madawala, Maria Marchante, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden Anthony Homer, Robert B Gilchrist, Lindsay E Wu
Fertility protection during chemotherapy treatment by boosting the NAD(P) + metabolome. EMBO molecular medicine (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging 4 (2) (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging 4 (2) (2024)
Laena Pernomian, Emily W Waigi, Vi Nguyen, Ahmed D Mohammed, Tiago J da Costa, Milene T Fontes, Jason Lee Kubinak, Andrew V Aitken, Vinicia Campana Biancardi, David A Sinclair, Cameron G McCarthy, Yunguan Wang, Wenbin Tan, Camilla Ferreira Wenceslau
A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice. bioRxiv : the preprint server for biology (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging 4 (2) (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging 4 (2) (2024)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Publisher Correction: Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging (2024)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Publisher Correction: Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging (2024)
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Albert K Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, David A Sinclair
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature aging 4 (2) (2024)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Yuancheng Ryan Lu, Xiao Tian, David A Sinclair
The Information Theory of Aging. Nature aging 3 (12) (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Lindsay E Wu, Corrine E Fiveash, Nicholas L Bentley, Myung-Jin Kang, Hemna Govindaraju, Jayne Alexandra Barbour, Brendan P Wilkins, Sarah E Hancock, Romanthi Madawala, Abhijit Das, Hassina Massudi, Catherine Li, Lynn-Jee Kim, Ashley S A Wong, Maria B Marinova, Ghazal Sultani, Abhirup Das, Neil A Youngson, David G Le Couteur, David A Sinclair, Nigel Turner
SIRT2 transgenic over-expression does not impact lifespan in mice. Aging cell (2023)
Yuancheng Ryan Lu, Xiao Tian, David A Sinclair
The Information Theory of Aging. Nature aging 3 (12) (2023)
Nicola Boekstein, Nir Barzilai, André Bertram, Joe Betts-LaCroix, Kristen Fortney, Stephen B Helliwell, Michael Hufford, Joan Mannick, Jerry McLaughlin, Jim Mellon, Eric Morgen, Nils Regge, Daisy A Robinton, David A Sinclair, Sergey Young, Risa Starr, Alex Zhavoronkov, James Peyer
Defining a longevity biotechnology company. Nature biotechnology (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Andrea Cipriano, Mahdi Moqri, Sun Y Maybury-Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A Sinclair, Vittorio Sebastiano
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nature aging 4 (1) (2023)
Yuancheng Ryan Lu, Xiao Tian, David A Sinclair
The Information Theory of Aging. Nature aging 3 (12) (2023)
João A Amorim, Giuseppe Coppotelli, Anabela P Rolo, Carlos M Palmeira, Jaime M Ross, David A Sinclair
Mitochondrial and metabolic dysfunction in ageing and age-related diseases. Nature reviews. Endocrinology 18 (4) (2022)
Adam Li, Amber L Mueller, Brad English, Anthony Arena, Daniel L Vera, Alice E Kane, David A Sinclair
Novel feature selection methods for construction of accurate epigenetic clocks. PLoS computational biology 18 (8) (2022)
Andrew J Scott, Martin Ellison, David A Sinclair
The economic value of targeting aging. Nature aging 1 (7) (2021)
Andrew J Scott, Martin Ellison, David A Sinclair
The economic value of targeting aging. Nature aging 1 (7) (2021)
Juan Alfonso Martínez-Greene, Karina Hernández-Ortega, Ricardo Quiroz-Baez, Resendis-Antonio Osbaldo, Israel Pichardo-Casas, David A Sinclair, Bogdan Budnik, Alfredo Hidalgo-Miranda, Eileen Uribe-Querol, María Del Pilar Ramos-Godínez, Eduardo Martinez-Martinez
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. Journal of extracellular vesicles 10 (6) (2021)
Andrew J Scott, Martin Ellison, David A Sinclair
The economic value of targeting aging. Nature aging 1 (7) (2021)
Andrew J Scott, Martin Ellison, David A Sinclair
The economic value of targeting aging. Nature aging 1 (7) (2021)
Michael B Schultz, Alice E Kane, Sarah J Mitchell, Michael R MacArthur, Elisa Warner, David S Vogel, James R Mitchell, Susan E Howlett, Michael S Bonkowski, David A Sinclair
Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty. Nature communications 11 (1) (2020)
Michael B Schultz, Alice E Kane, Sarah J Mitchell, Michael R MacArthur, Elisa Warner, David S Vogel, James R Mitchell, Susan E Howlett, Michael S Bonkowski, David A Sinclair
Age and life expectancy clocks based on machine learning analysis of mouse frailty. Nature communications 11 (1) (2020)
Michael B Schultz, Daniel Vera, David A Sinclair
Can artificial intelligence identify effective COVID-19 therapies? EMBO molecular medicine 12 (8) (2020)
Yuancheng Ryan Lu, Benedikt Brommer, Xiao Tian, Anitha Krishnan, Margarita Meer, Chen Wang, Daniel L Vera, Qiurui Zeng, Doudou Yu, Michael S Bonkowski, Jae-Hyun Yang, Songlin Zhou, Emma M Hoffmann, Margarete M Karg, Michael B Schultz, Alice E Kane, Noah Davidsohn, Ekaterina Korobkina, Karolina Chwalek, Luis A Rajman, George M Church, Konrad Hochedlinger, Vadim N Gladyshev, Steve Horvath, Morgan E Levine, Meredith S Gregory-Ksander, Bruce R Ksander, Zhigang He, David A Sinclair
Reprogramming to recover youthful epigenetic information and restore vision. Nature 588 (7836) (2020)
Jun Li, Michael S Bonkowski, Sébastien Moniot, Dapeng Zhang, Basil P Hubbard, Alvin J Y Ling, Luis A Rajman, Bo Qin, Zhenkun Lou, Vera Gorbunova, L Aravind, Clemens Steegborn, David A Sinclair
A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science (New York, N.Y.) 355 (6331) (2017)

David A Sinclair.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

David A Sinclair