David I Roper

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 23

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Scientific reports

Journal of medicinal chemistry

University of Warwick

University of Leicester (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Warwick Jun 01 2017

United Kingdom

Professor :: School of Life Sciences

University of Warwick Oct 01 2010 - May 31 2017

United Kingdom

Reader :: School of Life Sciences

University of Warwick Mar 01 2001 - Oct 01 2011

United Kingdom

Lecturer-Senior Lecturer :: Biological Sciences

University of York Oct 01 1996 - Mar 01 2001

United Kingdom

MRC Career Develoment Fellow :: Chemistry

University of York Aug 01 1990 - Oct 01 1996

United Kingdom

Postdoctoral researcher :: Chemistry

Education History

University of Leicester Oct 01 1987 - Oct 01 1990

United Kingdom

PHD :: Biochemistry

Publications

Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Jonathan Cook, Tyler C Baverstock, Martin B L McAndrew, David I Roper, Phillip J Stansfeld, Allister Crow
Activator-induced conformational changes regulate division-associated peptidoglycan amidases. Proceedings of the National Academy of Sciences of the United States of America 120 (24) (2023)
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Rie Nygaard, Chris L B Graham, Meagan Belcher Dufrisne, Jonathan D Colburn, Joseph G Pepe, Molly A Hydorn, Silvia Corradi, Chelsea M Brown, Khuram U Ashraf, Owen N Vickery, Nicholas S Briggs, John J Deering, Brian Kloss, Bruno Botta, Oliver B Clarke, Linda Columbus, Jonathan Dworkin, Phillip J Stansfeld, David I Roper, Filippo Mancia
Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex. Nature communications 14 (1) (2023)
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R Isberg, Christopher G Dowson, Adrian J Lloyd, Edward Geisinger, Allister Crow, David I Roper
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Khuram U Ashraf, Rie Nygaard, Owen N Vickery, Satchal K Erramilli, Carmen M Herrera, Thomas H McConville, Vasileios I Petrou, Sabrina I Giacometti, Meagan Belcher Dufrisne, Kamil Nosol, Allen P Zinkle, Chris L B Graham, Michael Loukeris, Brian Kloss, Karolina Skorupinska-Tudek, Ewa Swiezewska, David I Roper, Oliver Biggs Clarke, Anne-Catrin Uhlemann, Anthony A Kossiakoff, M Stephen Trent, Phillip J Stansfeld, Filippo Mancia
Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature 604 (7905) (2022)
Amanda J Dowson, Adrian J Lloyd, Andrew C Cuming, David I Roper, Lorenzo Frigerio, Christopher G Dowson
Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria. Plant physiology 190 (1) (2022)
Wendy Tran, Ali S Kusay, Paige M E Hawkins, Chen-Yi Cheung, Gayathri Nagalingam, Venugopal Pujari, Daniel J Ford, Alexander Stoye, Jessica L Ochoa, Rebecca E Audette, Elinor Hortle, Stefan H Oehlers, Susan A Charman, Roger G Linington, Eric J Rubin, Christopher G Dowson, David I Roper, Dean C Crick, Thomas Balle, Gregory M Cook, Warwick J Britton, Richard J Payne
Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors. Journal of medicinal chemistry 64 (23) (2021)
Chris L B Graham, Hector Newman, Francesca N Gillett, Katie Smart, Nicholas Briggs, Manuel Banzhaf, David I Roper
A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria. International journal of molecular sciences 22 (23) (2021)
Surya D Aggarwal, Adrian J Lloyd, Saigopalakrishna S Yerneni, Ana Rita Narciso, Jennifer Shepherd, David I Roper, Christopher G Dowson, Sérgio Raposo Filipe, N Luisa Hiller
A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Anita C Catherwood, Adrian J Lloyd, Julie A Tod, Smita Chauhan, Susan E Slade, Grzegorz P Walkowiak, Nicola F Galley, Avinash S Punekar, Katie Smart, Dean Rea, Neil D Evans, Michael J Chappell, David I Roper, Christopher G Dowson
Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by Escherichia coli PBP1B. Journal of the American Chemical Society 142 (11) (2020)
Jonathan Cook, Tyler C Baverstock, Martin B L McAndrew, Phillip J Stansfeld, David I Roper, Allister Crow
Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain. Proceedings of the National Academy of Sciences of the United States of America 117 (45) (2020)
Ahmad Massarweh, Michael Bosco, Isabelle Chantret, Thibaut Léger, Layla Jamal, David I Roper, Christopher G Dowson, Patricia Busca, Ahmed Bouhss, Christine Gravier-Pelletier, Stuart E H Moore
Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities. Molecules (Basel, Switzerland) 24 (11) (2019)
Erkin Kuru, Atanas Radkov, Xin Meng, Alexander Egan, Laura Alvarez, Amanda Dowson, Garrett Booher, Eefjan Breukink, David I Roper, Felipe Cava, Waldemar Vollmer, Yves Brun, Michael S VanNieuwenhze
Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis. ACS chemical biology 14 (12) (2019)
Alvin C K Teo, Sarah C Lee, Naomi L Pollock, Zoe Stroud, Stephen C L Hall, Alpesh Thakker, Andrew R Pitt, Timothy R Dafforn, Corinne M Spickett, David I Roper
Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein. Scientific reports 9 (1) (2019)
Sarah C Lee, Richard Collins, Yu-Pin Lin, Mohammed Jamshad, Claire Broughton, Sarah A Harris, Benjamin S Hanson, Cecilia Tognoloni, Rosemary A Parslow, Ann E Terry, Alison Rodger, Corinne J Smith, Karen J Edler, Robert Ford, David I Roper, Timothy R Dafforn
Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ. Scientific reports 9 (1) (2019)
Ricky Cain, Ramya Salimraj, Avinash S Punekar, Dom Bellini, Colin W G Fishwick, Lloyd Czaplewski, David J Scott, Gemma Harris, Christopher G Dowson, Adrian J Lloyd, David I Roper
Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase. Journal of medicinal chemistry 62 (21) (2019)
David Sychantha, Carys S Jones, Dustin J Little, Patrick Joseph Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke
In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). PLoS pathogens 13 (10) (2017)
Anh T Tran, Emma E Watson, Venugopal Pujari, Trent Conroy, Luke J Dowman, Andrew M Giltrap, Angel Pang, Weng Ruh Wong, Roger G Linington, Sebabrata Mahapatra, Jessica Saunders, Susan A Charman, Nicholas P West, Timothy D H Bugg, Julie Tod, Christopher G Dowson, David I Roper, Dean C Crick, Warwick J Britton, Richard J Payne
Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature communications 8 (2017)
Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W Thoroughgood, Katie J Simmons, Christopher G Dowson, Colin W G Fishwick, Luiz Pedro Sorio de Carvalho, David I Roper
Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nature communications 8 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

David I Roper