Stanislav Gobec

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Pharmaceuticals (Basel, Switzerland)

Molecules (Basel, Switzerland)

Journal of medicinal chemistry

ACS omega

University of Ljubljana

University of Ljubljana (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Ljubljana

Slovenia

Professor :: Faculty of Pharmacy

Education History

University of Ljubljana

Slovenia

PHD :: Faculty of Pharmacy

Publications

Mireia Toledano-Pinedo, Alicia Porro-Pérez, Linda Schäker-Hübner, Fernando Romero, Min Dong, Abdelouahid Samadi, Pedro Almendros, Isabel Iriepa, Òscar M Bautista-Aguilera, M Mercedes Rodríguez-Fernández, Cristina Solana-Manrique, Inmaculada Sanchis, Alba Mora-Morell, Ania Canseco Rodrìguez, Ana M Sànchez-Pérez, Damijan Knez, Stanislav Gobec, Aina Bellver-Sanchis, Belén Pérez, Alexey V Dobrydnev, Aizpea Artetxe-Zurutuza, Ander Matheu, Agata Siwek, Małgorzata Wolak, Grzegorz Satała, Andrzej J Bojarski, Agata Doroz-Płonka, Jadwiga Handzlik, Justyna Godyń, Anna Więckowska, Nuria Paricio, Christian Griñán-Ferré, Finn K Hansen, José Marco-Contelles
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases. Journal of medicinal chemistry (2024)
Katarina Grabrijan, Nika Strašek Benedik, Alen Krajnc, Krištof Bozovičar, Damijan Knez, Matic Proj, Irena Zdovc, Gobec Izidor Sosič, Carlos Contreras-Martel, Andrea Dessen, Martina Hrast Rambaher, Stanislav Gobec
Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s). Acta pharmaceutica (Zagreb, Croatia) 74 (3) (2024)
Nika Strašek Benedik, Ana Dolšak, Urban Švajger, Gobec Izidor Sosič, Stanislav Gobec, Matej Sova
Structural Optimization and Biological Evaluation of Isoxazolo[5,4 -d ]pyrimidines as Selective Toll-Like Receptor 7 Agonists. ACS omega 9 (2) (2024)
Nika Strašek Benedik, Ana Dolšak, Urban Švajger, Gobec Izidor Sosič, Stanislav Gobec, Matej Sova
Structural Optimization and Biological Evaluation of Isoxazolo[5,4 -d ]pyrimidines as Selective Toll-Like Receptor 7 Agonists. ACS omega 9 (2) (2024)
Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder
Biological Evaluation of Valeriana Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities-The Case of Valeriana carnosa Sm. (Caprifoliaceae) Studied in Mice. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder
Biological Evaluation of Valeriana Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities-The Case of Valeriana carnosa Sm. (Caprifoliaceae) Studied in Mice. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Rok Frlan, Martina Hrast Rambaher, Stanislav Gobec
Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues. ACS omega 8 (36) (2023)
Martina Hrast Rambaher, Irena Zdovc, Nina Kočevar Glavač, Stanislav Gobec, Rok Frlan
Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (-)-epicatechin. Journal of computer-aided molecular design (2023)
Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder
Biological Evaluation of Valeriana Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities-The Case of Valeriana carnosa Sm. (Caprifoliaceae) Studied in Mice. Pharmaceuticals (Basel, Switzerland) 16 (1) (2023)
Péter Ábrányi-Balogh, Aaron Keeley, György G Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast Rambaher, Damijan Knez, Janez Ilaš, Stanislav Gobec, György Miklós Keserű
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (12) (2022)
Matic Proj, Martina Hrast Rambaher, Damijan Knez, Krištof Bozovičar, Katarina Grabrijan, Anže Meden, Stanislav Gobec, Rok Frlan
Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe? ACS medicinal chemistry letters 13 (12) (2022)
Janez Konc, Samo Lešnik, Blaž Škrlj, Matej Sova, Matic Proj, Damijan Knez, Stanislav Gobec, Dušanka Janežič
ProBiS-Dock: A Hybrid Multitemplate Homology Flexible Docking Algorithm Enabled by Protein Binding Site Comparison. Journal of chemical information and modeling 62 (6) (2022)
Péter Ábrányi-Balogh, Aaron Keeley, György G Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast Rambaher, Damijan Knez, Janez Ilaš, Stanislav Gobec, György Miklós Keserű
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (12) (2022)
Damijan Knez, Stanislav Gobec, Martina Hrast Rambaher
Screening of Big Pharma's Library against Various in-house Biological Targets. Molecules (Basel, Switzerland) 27 (14) (2022)
Péter Ábrányi-Balogh, Aaron Keeley, György G Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast Rambaher, Damijan Knez, Janez Ilaš, Stanislav Gobec, György Miklós Keserű
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (12) (2022)
Péter Ábrányi-Balogh, Aaron Keeley, György G Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast Rambaher, Damijan Knez, Janez Ilaš, Stanislav Gobec, György Miklós Keserű
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors. Pharmaceuticals (Basel, Switzerland) 15 (12) (2022)
Mihajlo Gajic, Damijan Knez, Gobec Izidor Sosič, Janez Mravljak, Anže Meden, Urban Košak, Luisa Leitzbach, Sven George, Bettina Hofmann, Aleksandra Zivkovic, Dieter Steinhilber, Holger Stark, Stanislav Gobec, Andrija Šmelcerović, Marko Anderluh
Repurposing of 8-Hydroxyquinoline-Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors. ChemMedChem 17 (5) (2022)
Bernarda Majc, Anamarija Habič, Metka Novak, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Vera Župunski, Urša Pečar Fonović, Damijan Knez, Nace Zidar, Stanislav Gobec, Janko Kos, Tamara Lah Turnšek, Anja Pišlar, Barbara Breznik
Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors. International journal of molecular sciences 23 (3) (2022)
Óscar M Bautista-Aguilera, José M Alonso, Marco Catto, Isabel Iriepa, Damijan Knez, Stanislav Gobec, José Marco-Contelles
N -Hydroxy- N -Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases. Molecules (Basel, Switzerland) 27 (21) (2022)
Matic Proj, Martina Hrast Rambaher, Damijan Knez, Krištof Bozovičar, Katarina Grabrijan, Anže Meden, Stanislav Gobec, Rok Frlan
Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe? ACS medicinal chemistry letters 13 (12) (2022)
Daniel Diez-Iriepa, Damijan Knez, Stanislav Gobec, Isabel Iriepa, Cristóbal de Los Ríos, Isaac Bravo, Francisco López Muñoz, José Marco-Contelles, Dimitra Hadjipavlou-Litina
Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment. Antioxidants (Basel, Switzerland) 11 (9) (2022)
Katarina Grabrijan, Nika Strašek, Stanislav Gobec
Synthesis of 3-Amino-4-substituted Monocyclic ß-Lactams-Important Structural Motifs in Medicinal Chemistry. International journal of molecular sciences 23 (1) (2021)
Katja Pirc, Vesna Hodnik, Tina Snoj, Tea Lenarčič, Simon Caserman, Marjetka Podobnik, Hannah Böhm, Isabell Albert, Anita Kotar, Janez Plavec, Jure Borišek, Martina Damuzzo, Alessandra Magistrato, Boris Brus, Gobec Izidor Sosič, Stanislav Gobec, Thorsten Nürnberger, Gregor Anderluh
Nep1-like proteins as a target for plant pathogen control. PLoS pathogens 17 (4) (2021)
Tjaša Mazej, Damijan Knez, Anže Meden, Stanislav Gobec, Matej Sova
4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B. Molecules (Basel, Switzerland) 26 (14) (2021)
Levente Kollár, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez, Tímea Imre, Ágnes Gömöry, László Petri, Péter Ábrányi-Balogh, Dorottya Csányi, György G Ferenczy, Stanislav Gobec, Gobec Izidor Sosič, György Miklós Keserű
Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads. Cells 10 (12) (2021)
László Petri, Péter Ábrányi-Balogh, Imre Tímea, Gyula Pálfy, András Perczel, Damijan Knez, Martina Hrast, Martina Gobec, Izidor Sosič, Kinga Nyíri, Beáta G Vértessy, Niklas Jänsch, Charlotte Desczyk, Franz-Josef Meyer-Almes, Iza Ogris, Simona Golič Grdadolnik, Luca Giacinto Iacovino, Claudia Binda, Stanislav Gobec, György M Keserű
Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments. Chembiochem : a European journal of chemical biology 22 (4) (2020)
Damijan Knez, Natalia Colettis, Luca G Iacovino, Matej Sova, Anja Pišlar, Janez Konc, Samo Lešnik, Josefina Higgs, Fabiola Kamecki, Irene Mangialavori, Ana Dolšak, Simon Žakelj, Jurij Trontelj, Janko Kos, Claudia Binda, Mariel Marder, Stanislav Gobec
Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B. Journal of medicinal chemistry 63 (3) (2020)
Ana Mitrović, Jakob Kljun, Gobec Izidor Sosič, Matija Uršič, Anton Meden, Stanislav Gobec, Janko Kos, Iztok Turel
Organoruthenated Nitroxoline Derivatives Impair Tumor Cell Invasion through Inhibition of Cathepsin B Activity. Inorganic chemistry 58 (18) (2019)
Lena Decuyper, Katarina Magdalenić, Marie Verstraete, Marko Jukič, Gobec Izidor Sosič, Eric Sauvage, Ana Maria Amoroso, Olivier Verlaine, Bernard Joris, Stanislav Gobec, Matthias D'hooghe
α-Unsaturated 3-Amino-1-carboxymethyl-β-lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment. Chemistry (Weinheim an der Bergstrasse, Germany) (2019)
Anna Więckowska, Tomasz Wichur, Justyna Godyń, Adam Bucki, Monika Marcinkowska, Agata Siwek, Krzysztof Więckowski, Paula Zaręba, Damijan Knez, Monika Głuch-Lutwin, Grzegorz Kazek, Gniewomir Latacz, Kamil Mika, Marcin Kołaczkowski, Jan Korabecny, Ondrej Soukup, Marketa Benkova, Katarzyna Kieć-Kononowicz, Stanislav Gobec, Barbara Malawska
Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease. ACS chemical neuroscience 9 (5) (2018)
Marko Jukič, Stanislav Gobec, Matej Sova
Reaching toward underexplored targets in antibacterial drug design. Drug development research 80 (1) (2018)
Lena Decuyper, Sari Deketelaere, Lore Vanparys, Marko Jukič, Gobec Izidor Sosič, Eric Sauvage, Ana Maria Amoroso, Olivier Verlaine, Bernard Joris, Stanislav Gobec, Matthias D'hooghe
In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3-Amino-1-carboxymethyl-β-lactams as Inhibitors of Penicillin-Binding Proteins of Resistant Bacteria. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (57) (2018)
Martina Hrast, Marko Jukič, Delphine Patin, Julie Tod, Christopher G Dowson, David I Roper, Hélène Barreteau, Stanislav Gobec
In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB. Chemical biology & drug design 91 (6) (2018)
Dawid Panek, Anna Więckowska, Jakub Jończyk, Justyna Godyń, Marek Bajda, Tomasz Wichur, Anna Pasieka, Damijan Knez, Anja Pišlar, Jan Korabecny, Ondrej Soukup, Vendula Sepsova, Raimon Sabatè, Janko Kos, Stanislav Gobec, Barbara Malawska
Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents. ACS chemical neuroscience 9 (5) (2018)
Urban Košak, Boris Brus, Damijan Knez, Simon Žakelj, Jurij Trontelj, Anja Pišlar, Roman Šink, Marko Jukič, Marko Živin, Adrian Podkowa, Florian Nachon, Xavier Brazzolotto, Jure Stojan, Janko Kos, Nicolas Coquelle, Kinga Sałat, Jacques-Philippe Colletier, Stanislav Gobec
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity. Journal of medicinal chemistry 61 (1) (2017)
Marko Jukič, Janez Konc, Stanislav Gobec, Dušanka Janežič
Identification of Conserved Water Sites in Protein Structures for Drug Design. Journal of chemical information and modeling 57 (12) (2017)
Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W Thoroughgood, Katie J Simmons, Christopher G Dowson, Colin W G Fishwick, Luiz Pedro Sorio de Carvalho, David I Roper
Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nature communications 8 (1) (2017)
Urša Pečar Fonović, Ana Mitrović, Damijan Knez, Tanja Jakoš, Anja Pišlar, Boris Brus, Bojan Doljak, Jure Stojan, Simon Žakelj, Jurij Trontelj, Stanislav Gobec, Janko Kos
Identification and characterization of the novel reversible and selective cathepsin X inhibitors. Scientific reports 7 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Stanislav Gobec