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David J Beech

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 13

Top Venues

Scientific reports

The Journal of physiology

Communications biology

The Journal of biological chemistry

University of Leeds

St George's, University of London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Leeds Aug 1o 2000

United Kingdom

Professor :: Biological Sciences, Medicine

Education History

St George's, University of London Oct 1o 1988

United Kingdom

PHD :: Pharmacology

Publications

Nicoletta Murciano, Maria Giustina Rotordam, Nadine Becker, Melanie J Ludlow, Gregory Parsonage, Alexis Darras, Lars Kaestner, David J Beech, Michael George, Niels Fertig, Markus Rapedius, Andrea Brüggemann
A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation. The Journal of general physiology 155 (12) (2023)
Eulashini Chuntharpursat-Bon, Oleksandr V Povstyan, Melanie J Ludlow, David J Carrier, Marjolaine Debant, Jian Shi, Hannah J Gaunt, Claudia C Bauer, Alistair P Curd, T Simon Futers, Paul D Baxter, Michelle Peckham, Stephen P Muench, Antony D Adamson, Neil Humphreys, Sarka Tumova, Robin S Bon, Richard Cubbon, Laeticia Lichtenstein, David J Beech
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications biology 6 (1) (2023)
Naima Endesh, Eulashini Chuntharpursat-Bon, Charlotte Revill, Nadira Y Yuldasheva, T Simon Futers, Gregory Parsonage, Neil E Humphreys, Antony D Adamson, Lara C Morley, Richard M Cubbon, K Raj Prasad, Richard Foster, Laeticia Lichtenstein, David J Beech
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver international : official journal of the International Association for the Study of the Liver (2023)
Fiona Bartoli, Elizabeth L Evans, Nicola M Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T Simon Futers, Neil A Turner, David J Beech
Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice. Cells 11 (7) (2022)
Gregory Parsonage, Kevin Cuthbertson, Naima Endesh, Nicoletta Murciano, Adam J Hyman, Charlotte H Revill, Oleksandr V Povstyan, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Melanie J Ludlow, T Simon Futers, Laeticia Lichtenstein, Jacob A Kinsella, Fiona Bartoli, Maria Giustina Rotordam, Nadine Becker, Andrea Brüggemann, Richard Foster, David J Beech
Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British journal of pharmacology (2022)
David J Beech, Laeticia Lichtenstein
RNA and the PIEZO force sensor. Cell research 30 (10) (2021)
David J Wright, Katie J Simmons, Rachel M Johnson, David J Beech, Stephen P Muench, Robin S Bon
Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. Communications biology 3 (1) (2020)
Vincenza Caolo, Marjolaine Debant, Naima Endesh, T Simon Futers, Laeticia Lichtenstein, Fiona Bartoli, Gregory Parsonage, Elizabeth Av Jones, David J Beech
Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. eLife 9 (2020)
Nicola M Blythe, Katsuhiko Muraki, Melanie J Ludlow, Vasili Stylianidis, Hamish T J Gilbert, Elizabeth L Evans, Kevin Cuthbertson, Richard Foster, Joe Swift, Jing Li, Mark J Drinkhill, Frans A van Nieuwenhoven, Karen E Porter, David J Beech, Neil A Turner
Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion. The Journal of biological chemistry 294 (46) (2019)
Baptiste Rode, Nadira Y Yuldasheva, Paul D Baxter, Alicia Sedo, Justin F-X Ainscough, Michael Shires, Mark T Kearney, Marc A Bailey, Stephen B Wheatcroft, David J Beech
TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice. Scientific reports 9 (1) (2019)
David J Beech, Bailong Xiao
Piezo channel mechanisms in health and disease. The Journal of physiology 596 (6) (2019)
Vijayalakshmi Deivasikamani, Savitha Dhayalan, Yilizila Abudushalamu, Romana Mughal, Asjad Visnagri, Kevin Cuthbertson, Jason L Scragg, Tim S Munsey, Hema Viswambharan, Katsuhiko Muraki, Richard Foster, Asipu Sivaprasadarao, Mark T Kearney, David J Beech, Piruthivi Sukumar
Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific reports 9 (1) (2019)
David J Beech
Endothelial Piezo1 channels as sensors of exercise. The Journal of physiology 596 (6) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

David J Beech