David M Perrin (David Perrin)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Topics

Positron Emission Tomography

Top Venues

Angewandte Chemie (International ed. in English)

Chemistry (Weinheim an der Bergstrasse, Germany)

The Journal of organic chemistry

Journal of labelled compounds & radiopharmaceuticals

This page only lists publications with an associated author ORCID identifier.

Publications

Mihajlo Todorovic, Antoine Blanc, Zhou Wang, Jerome Lozada, Juliette Froelich, Jutta Zeisler, Chengcheng Zhang, Helen Merkens, Francois Benard, David M Perrin
5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (19) (2024)
Shanal Gunasekera, Alla Pryyma, Jimin Jung, Rebekah Greenwood, Brian O Patrick, David M Perrin
Diphenylphosphinylhydroxylamine (DPPH) Affords Late-Stage S-imination to access free-NH Sulfilimines and Sulfoximines. Angewandte Chemie (International ed. in English) (2024)
Shambhu Deo Chandra, Shanal Gunasekera, Benjamin Philipp Noichl, Brian O Patrick, David M Perrin
Synthesis of (2 S ,3 R ,4 R )-Dihydroxyisoleucine for Use in Amatoxin Synthesis. The Journal of organic chemistry (2024)
Mihajlo Todorovic, Antoine Blanc, Zhou Wang, Jerome Lozada, Juliette Froelich, Jutta Zeisler, Chengcheng Zhang, Helen Merkens, Francois Benard, David M Perrin
5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Shanal Gunasekera, Alla Pryyma, Jimin Jung, Rebekah Greenwood, Brian O Patrick, David M Perrin
Diphenylphosphinylhydroxylamine (DPPH) Affords Late-Stage S-imination to access free-NH Sulfilimines and Sulfoximines. Angewandte Chemie (International ed. in English) 63 (13) (2024)
Shanal Gunasekera, Alla Pryyma, Jimin Jung, Rebekah Greenwood, Brian O Patrick, David M Perrin
Diphenylphosphinylhydroxylamine (DPPH) Affords Late-Stage S-imination to access free-NH Sulfilimines and Sulfoximines. Angewandte Chemie (International ed. in English) (2024)
Mihajlo Todorovic, Antoine Blanc, Zhou Wang, Jerome Lozada, Juliette Froelich, Jutta Zeisler, Chengcheng Zhang, Helen Merkens, Francois Benard, David M Perrin
5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (19) (2024)
Jerome Lozada, Wen Xuan Lin, Rosana M Cao-Shen, Ruyin Astoria Tai, David M Perrin
Salt Metathesis: Tetrafluoroborate Anion Rapidly Fluoridates Organoboronic Acids to give Organotrifluoroborates. Angewandte Chemie (International ed. in English) (2023)
Jerome Lozada, Hsiou-Ting Kuo, Wen Xuan Lin, Kuo-Shyan Lin, François Bénard, David M Perrin
Imidazolium-methylene-trifluoroborate: A novel radioprosthetic group validated with preclinical 18 F-Positron Emission Tomography imaging of Prostate Specific Membrane Antigen in mice. Journal of labelled compounds & radiopharmaceuticals (2023)
Jerome Lozada, Hsiou-Ting Kuo, Wen Xuan Lin, Kuo-Shyan Lin, François Bénard, David M Perrin
Imidazolium-Methylene-Trifluoroborate: a Novel Radioprosthetic Group Validated with Preclinical 18 F-PET Imaging of PSMA in Mice. Journal of labelled compounds & radiopharmaceuticals (2023)
Antoine Blanc, Mihajlo Todorovic, Iulia Dude, Helen Merkens, François Bénard, David M Perrin
Toward tryptathionine-stapled one-bead-one-compound (OBOC) libraries: solid phase synthesis of a bioactive octretoate analog. Organic & biomolecular chemistry (2023)
Jerome Lozada, Hsiou-Ting Kuo, Wen Xuan Lin, Kuo-Shyan Lin, François Bénard, David M Perrin
Imidazolium-methylene-trifluoroborate: A novel radioprosthetic group validated with preclinical 18 F-Positron Emission Tomography imaging of Prostate Specific Membrane Antigen in mice. Journal of labelled compounds & radiopharmaceuticals (2023)
Mihajlo Todorovic, Paul Rivollier, Antonio A W L Wong, Zhou Wang, Alla Pryyma, Tuan Trung Nguyen, Kayla C Newell, Juliette Froelich, David M Perrin
Rationally Designed Amanitins Achieve Enhanced Cytotoxicity. Journal of medicinal chemistry 65 (15) (2022)
Omar Sadek, Laura Abad Galán, Frédéric Gendron, Bruno Baguenard, Stéphan Guy, Amina Bensalah-Ledoux, Boris Le Guennic, Olivier Maury, David M Perrin, Emmanuel Gras
Chiral Benzothiazole Monofluoroborate Featuring Chiroptical and Oxygen-Sensitizing Properties: Synthesis and Photophysical Studies. The Journal of organic chemistry 86 (17) (2021)
Chido M Hambira, Kaveh Matinkhoo, Alla Pryyma, Brian O Patrick, David M Perrin
Scaling Amatoxin Synthesis with an Improved Route to (2S,3R,4R)-Dihydroxyisoleucine Exemplified by a Toxic, Clickable α-Amanitin Analogue. The Journal of organic chemistry 86 (7) (2021)
Alla Pryyma, Kaveh Matinkhoo, Yong Jia Bu, Helen Merkens, Zhengxing Zhang, Francois Bénard, David M Perrin
Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells. RSC chemical biology 3 (1) (2021)
Kaveh Matinkhoo, Alla Pryyma, Antonio A W L Wong, David M Perrin
Synthesis and evaluation of "Ama-Flash", a photocaged amatoxin prodrug for light-activated RNA Pol II inhibition and cell death. Chemical communications (Cambridge, England) 57 (75) (2021)
Kaveh Matinkhoo, Antonio A W L Wong, Chido M Hambira, Brandon Kato, Charlie Wei, Christoph Müller, Torsten Hechler, Alexandra Braun, Francesca Gallo, Andreas Pahl, David M Perrin
Design, Synthesis, and Biochemical Evaluation of Alpha-Amanitin Derivatives Containing Analogs of the trans-Hydroxyproline Residue for Potential Use in Antibody-Drug Conjugates. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (40) (2021)
Daniel Kwon, Jerome Lozada, Zhengxing Zhang, Jutta Zeisler, Richel Poon, Chengcheng Zhang, Áron Roxin, Kuo-Shyan Lin, David M Perrin, François Bénard
High-Contrast CXCR4-Targeted 18F-PET Imaging Using a Potent and Selective Antagonist. Molecular pharmaceutics 18 (1) (2020)
Alla Pryyma, Shanal Gunasekera, Joshua Lewin, David M Perrin
Rapid, High-Yielding Solid-Phase Synthesis of Cathepsin-B Cleavable Linkers for Targeted Cancer Therapeutics. Bioconjugate chemistry 31 (12) (2020)
Antonio A W L Wong, Jerome Lozada, Mathieu L Lepage, Chengcheng Zhang, Helen Merkens, Jutta Zeisler, Kuo-Shyan Lin, François Bénard, David M Perrin
Synthesis and 18F-radiolabeling of thymidine AMBF3 conjugates. RSC medicinal chemistry 11 (5) (2020)
Alla Pryyma, Kaveh Matinkhoo, Antonio A W L Wong, David M Perrin
Meeting key synthetic challenges in amanitin synthesis with a new cytotoxic analog: 5'-hydroxy-6'-deoxy-amanitin. Chemical science 11 (43) (2020)
Mathieu L Lepage, Hsiou-Ting Kuo, Áron Roxin, Sungjoon Huh, Zhengxing Zhang, Rajaguru Kandasamy, Helen Merkens, Joel O Kumlin, Alan Limoges, Stefan K Zeisler, Kuo-Shyan Lin, François Bénard, David M Perrin
Toward 18 F-Labeled Theranostics: A Single Agent that Can Be Labeled with 18 F, 64 Cu, or 177 Lu. Chembiochem : a European journal of chemical biology 21 (7) (2019)
Áron Roxin, Chengcheng Zhang, Sungjoon Huh, Mathieu L Lepage, Zhengxing Zhang, Kuo-Shyan Lin, François Bénard, David M Perrin
A Metal-Free DOTA-Conjugated 18F-Labeled Radiotracer: [18F]DOTA-AMBF3-LLP2A for Imaging VLA-4 Over-Expression in Murine Melanoma with Improved Tumor Uptake and Greatly Enhanced Renal Clearance. Bioconjugate chemistry 30 (4) (2019)
Chengcheng Zhang, Zhengxing Zhang, Helen Merkens, Jutta Zeisler, Nadine Colpo, Navjit Hundal-Jabal, David M Perrin, Kuo-Shyan Lin, François Bénard
18F-Labeled Cyclized α-Melanocyte-Stimulating Hormone Derivatives for Imaging Human Melanoma Xenograft with Positron Emission Tomography. Scientific reports 9 (1) (2019)
Alla Pryyma, Yong Jia Bu, Yonnie Wai, Brian O Patrick, David M Perrin
Synthesis and Activation of Bench-Stable 3a-Fluoropyrroloindolines as Latent Electrophiles for the Synthesis of C-2-Thiol-Substituted Tryptophans and C-3a-Substituted Pyrroloindolines. Organic letters 21 (20) (2019)
Mihajlo Todorovic, Katerina D Schwab, Jutta Zeisler, Chengcheng Zhang, François Bénard, David M Perrin
Fluorescent Isoindole Crosslink (FlICk) Chemistry: A Rapid, User-friendly Stapling Reaction. Angewandte Chemie (International ed. in English) 58 (40) (2019)
Tharwat Mohy El Dine, Omar Sadek, Emmanuel Gras, David M Perrin
Expanding the Balz-Schiemann Reaction: Organotrifluoroborates Serve as Competent Sources of Fluoride Ion for Fluoro-Dediazoniation. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (56) (2018)
Yajun Wang, Erkai Liu, Curtis H Lam, David M Perrin
A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover. Chemical science 9 (7) (2018)
Chengcheng Zhang, Zhengxing Zhang, Kuo-Shyan Lin, Joseph Lau, Jutta Zeisler, Nadine Colpo, David M Perrin, François Bénard
Melanoma Imaging Using 18F-Labeled α-Melanocyte-Stimulating Hormone Derivatives with Positron Emission Tomography. Molecular pharmaceutics 15 (6) (2018)
Kaveh Matinkhoo, Alla Pryyma, Mihajlo Todorovic, Brian O Patrick, David M Perrin
Synthesis of the Death-Cap Mushroom Toxin α-Amanitin. Journal of the American Chemical Society 140 (21) (2018)
Yajun Wang, Nicole Ng, Erkai Liu, Curtis H Lam, David M Perrin
Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selection. Organic & biomolecular chemistry 15 (3) (2018)
Marleen Renders, Emily Miller, Curtis H Lam, David M Perrin
Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria. Organic & biomolecular chemistry 15 (9) (2018)
Mathieu L Lepage, Samson Lai, Nicolas Peressin, Romain Hadjerci, Brian O Patrick, David M Perrin
Direct Access to MIDA Acylboronates through Mild Oxidation of MIDA Vinylboronates. Angewandte Chemie (International ed. in English) 56 (48) (2017)