Dimitrios Tsikas (Dimitros Tsikas, D Tsikas)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 59

Top Topics

Mass Spectrometry

Transforming Growth Factor

Cystic Fibrosis

Top Venues

Molecules (Basel, Switzerland)

Journal of clinical medicine

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Rene A Posma, Stephan J L Bakker, Maarten W Nijsten, Daniel J Touw, Dimitrios Tsikas
Comprehensive GC-MS Measurement of Amino Acids, Metabolites, and Malondialdehyde in Metformin-Associated Lactic Acidosis at Admission and during Renal Replacement Treatment. Journal of clinical medicine 13 (13) (2024)
Dimitrios Tsikas
Application of the Bland-Altman and Receiver Operating Characteristic (ROC) Approaches to Study Isotope Effects in Gas Chromatography-Mass Spectrometry Analysis of Human Plasma, Serum and Urine Samples. Molecules (Basel, Switzerland) 29 (2) (2024)
Dimitrios Tsikas
Application of the Bland-Altman and Receiver Operating Characteristic (ROC) Approaches to Study Isotope Effects in Gas Chromatography-Mass Spectrometry Analysis of Human Plasma, Serum and Urine Samples. Molecules (Basel, Switzerland) 29 (2) (2024)
Dimitrios Tsikas
Application of the Bland-Altman and Receiver Operating Characteristic (ROC) Approaches to Study Isotope Effects in Gas Chromatography-Mass Spectrometry Analysis of Human Plasma, Serum and Urine Samples. Molecules (Basel, Switzerland) 29 (2) (2024)
Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. eLife 13 (2024)
Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata
Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. eLife 13 (2024)
Dimitrios Tsikas
Application of the Bland-Altman and Receiver Operating Characteristic (ROC) Approaches to Study Isotope Effects in Gas Chromatography-Mass Spectrometry Analysis of Human Plasma, Serum and Urine Samples. Molecules (Basel, Switzerland) 29 (2) (2024)
Lea Kukoc-Modun, Tomislav Kraljevic, Dimitrios Tsikas, Tony G Spassov, Spas D Kolev
Determination of N -Acetyl-L-cysteine Ethyl Ester (NACET) by Sequential Injection Analysis. Sensors (Basel, Switzerland) 24 (2) (2024)
Lea Kukoc-Modun, Tomislav Kraljevic, Dimitrios Tsikas, Tony G Spassov, Spas D Kolev
Determination of N -Acetyl-L-cysteine Ethyl Ester (NACET) by Sequential Injection Analysis. Sensors (Basel, Switzerland) 24 (2) (2024)
Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. eLife 13 (2024)
Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. eLife 13 (2024)
Lea Kukoc-Modun, Tomislav Kraljevic, Dimitrios Tsikas, Tony G Spassov, Spas D Kolev
Determination of N -Acetyl-L-cysteine Ethyl Ester (NACET) by Sequential Injection Analysis. Sensors (Basel, Switzerland) 24 (2) (2024)
Rene A Posma, Stephan J L Bakker, Maarten W Nijsten, Daniel J Touw, Dimitrios Tsikas
Comprehensive GC-MS Measurement of Amino Acids, Metabolites, and Malondialdehyde in Metformin-Associated Lactic Acidosis at Admission and during Renal Replacement Treatment. Journal of clinical medicine 13 (13) (2024)
Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata
Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. eLife 13 (2024)
Dimitrios Tsikas, Bibiana Beckmann, Svetlana Baskal, Gorig Brunner
Pentafluoropropionic Anhydride Derivatization and GC-MS Analysis of Histamine, Agmatine, Putrescine, and Spermidine: Effects of Solvents and Starting Column Temperature. Molecules (Basel, Switzerland) 28 (3) (2023)
Dimitrios Tsikas
Mass Spectrometry-Based Evaluation of the Bland-Altman Approach: Review, Discussion, and Proposal. Molecules (Basel, Switzerland) 28 (13) (2023)
Harrina Erlianti Rahardjo, Viktoria Märker, Dimitrios Tsikas, Markus A Kuczyk, Stefan Ückert, Andreas Bannowsky
Fibrotic Diseases of the Human Urinary and Genital Tract: Current Understanding and Potential Strategies for Treatment. Journal of clinical medicine 12 (14) (2023)
Dimitrios Tsikas, Bibiana Beckmann
Quality Control in Targeted GC-MS for Amino Acid-OMICS. Metabolites 13 (9) (2023)
Dimitrios Tsikas, Bibiana Beckmann, Svetlana Baskal, Gorig Brunner
Pentafluoropropionic Anhydride Derivatization and GC-MS Analysis of Histamine, Agmatine, Putrescine, and Spermidine: Effects of Solvents and Starting Column Temperature. Molecules (Basel, Switzerland) 28 (3) (2023)
Dimitrios Tsikas, Stefanos A Tsikas, Marie Mikuteit, Stefan Ückert
Circulating and Urinary Concentrations of Malondialdehyde in Aging Humans in Health and Disease: Review and Discussion. Biomedicines 11 (10) (2023)
Lisa Eggenkemper, Anne Schlegtendal, Christoph Maier, Thomas Lücke, Folke Brinkmann, Bibiana Beckmann, Dimitrios Tsikas, Cordula Koerner-Rettberg
Impaired Nitric Oxide Synthetase Activity in Primary Ciliary Dyskinesia-Data-Driven Hypothesis. Journal of clinical medicine 12 (18) (2023)
Dimitrios Tsikas
Malondialdehyde-Induced Post-Translational Modification of Human Hemoglobin. Journal of proteome research (2023)
Dimitrios Tsikas, Bibiana Beckmann, Svetlana Baskal, Gorig Brunner
Pentafluoropropionic Anhydride Derivatization and GC-MS Analysis of Histamine, Agmatine, Putrescine, and Spermidine: Effects of Solvents and Starting Column Temperature. Molecules (Basel, Switzerland) 28 (3) (2023)
Dimitrios Tsikas
GC-MS Studies on Nitric Oxide Autoxidation and S -Nitrosothiol Hydrolysis to Nitrite in pH-Neutral Aqueous Buffers: Definite Results Using 15 N and 18 O Isotopes. Molecules (Basel, Switzerland) 28 (11) (2023)
Dimitrios Tsikas, Björn Redfors
Pilot Study on Acute Effects of Pharmacological Intraperitoneal L-Homoarginine on Homeostasis of Lysine and Other Amino Acids in a Rat Model of Isoprenaline-Induced Takotsubo Cardiomyopathy. International journal of molecular sciences 23 (9) (2022)
Svetlana Baskal, Stefanos A Tsikas, Olga Begou, Alexander Bollenbach, Sigurd Lenzen, Anne Jörns, Dimitrios Tsikas
Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1 -iddm Rat, an Animal Model of Human Type 1 Diabetes. International journal of molecular sciences 23 (3) (2022)
Beatrice Hanusch, Kathrin Sinningen, Folke Brinkmann, Stefanie Dillenhöfer, Mirjam Frank, Karl-Heinz Jöckel, Cordula Koerner-Rettberg, Martin Holtmann, Tanja Legenbauer, Christian Langrock, Thomas Reinehr, Patricia Maasjosthusmann, Bibiana Beckmann, Hamelmann Eckard, Dimitrios Tsikas, Thomas Lücke
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases. International journal of molecular sciences 23 (4) (2022)
Svetlana Baskal, Alexander Bollenbach, Bettina Henzi, Patricia Hafner, Dirk Fischer, Dimitrios Tsikas
Stable-Isotope Dilution GC-MS Measurement of Metformin in Human Serum and Urine after Derivatization with Pentafluoropropionic Anhydride and Its Application in Becker Muscular Dystrophy Patients Administered with Metformin, l-Citrulline, or Their Combination. Molecules (Basel, Switzerland) 27 (12) (2022)
Dimitrios Tsikas, Norbert Maassen, Antonie Thorns, Armin Finkel, Moritz Lützow, Magdalena Aleksandra Röhrig, Larissa Sarah Blau, Laurianne Dimina, François Mariotti, Bibiana Beckmann, Vladimir Shushakov, Mirja Jantz
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise. International journal of molecular sciences 23 (18) (2022)
Alexander Bollenbach, Svetlana Baskal, Catharina Martha Cornelia Mels, Ruan Kruger, Dimitrios Tsikas
Unusual Derivatization of Methylmalonic Acid with Pentafluorobenzyl Bromide to a Tripentafluorobenzyl Derivative and Its Stable-Isotope Dilution GC-MS Measurement in Human Urine. Molecules (Basel, Switzerland) 27 (16) (2022)
Svetlana Baskal, Dimitrios Tsikas
Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form N ε -Carboxymethyl-Lysine, N ε -Carboxyethyl-Lysine and N ε -Hydroxymethyl-Lysine. International journal of molecular sciences 23 (7) (2022)
Svetlana Baskal, Annette Kaiser, Catharina Mels, Ruan Kruger, Dimitrios Tsikas
Specific and sensitive GC-MS analysis of hypusine, N ε -(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study. Amino acids 54 (7) (2022)
Alexander Bollenbach, Dimitrios Tsikas
GC-MS Studies on the Conversion and Derivatization of γ-Glutamyl Peptides to Pyroglutamate (5-Oxo-Proline) Methyl Ester Pentafluoropropione Amide Derivatives. Molecules (Basel, Switzerland) 27 (18) (2022)
Svetlana Baskal, Laurianne Dimina, Stefanos A Tsikas, Laurent Mosoni, Didier Remond, François Mariotti, Dimitrios Tsikas
Lysine and homoarginine are closely interrelated metabolites in the rat. Amino acids 54 (6) (2022)
Svetlana Baskal, Alexander Bollenbach, Dimitrios Tsikas
GC-MS Discrimination of Citrulline from Ornithine and Homocitrulline from Lysine by Chemical Derivatization: Evidence of Formation of N5-Carboxy-ornithine and N6-Carboxy-lysine. Molecules (Basel, Switzerland) 26 (8) (2021)
Stefan Ückert, Karin Richter, Klaus-Dieter Fischer, Dimitrios Tsikas, Markus Antonius Kuczyk
Re-evaluation of the immunohistochemical distribution of isoforms of nitric oxide synthase in the human prostate: A light and electron microscopical study. Andrologia 53 (7) (2021)
Dimitrios Tsikas
GC-MS Analysis of Biological Nitrate and Nitrite Using Pentafluorobenzyl Bromide in Aqueous Acetone: A Dual Role of Carbonate/Bicarbonate as an Enhancer and Inhibitor of Derivatization. Molecules (Basel, Switzerland) 26 (22) (2021)
Lea Kukoc-Modun, Tomislav Kraljević, Dimitrios Tsikas, Njegomir Radić, Darko Modun
Determination of N-Acetyl-l-cysteine Ethyl Ester (NACET) by Flow Injection Analysis and Spectrophotometric Detection Using Different Thiol-Sensitive Ligands. Molecules (Basel, Switzerland) 26 (22) (2021)
Dimitrios Tsikas
Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface. Amino acids 53 (4) (2021)
Dimitrios Tsikas, Stepan Gambaryan
Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Svetlana Baskal, Adrian Post, Daan Kremer, Alexander Bollenbach, Stephan J L Bakker, Dimitrios Tsikas
Urinary excretion of amino acids and their advanced glycation end-products (AGEs) in adult kidney transplant recipients with emphasis on lysine: furosine excretion is associated with cardiovascular and all-cause mortality. Amino acids 53 (11) (2021)
Svetlana Baskal, Petra Büttner, Sarah Werner, Christian Besler, Philipp Lurz, Holger Thiele, Dimitrios Tsikas
Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats. Amino acids (2021)
Olga Begou, Kathrin Weber, Bibiana Beckmann, Dimitrios Tsikas
GC-MS Studies on Derivatization of Creatinine and Creatine by BSTFA and Their Measurement in Human Urine. Molecules (Basel, Switzerland) 26 (11) (2021)
Olga Begou, Antigoni Pavlaki, Olga Deda, Alexander Bollenbach, Kathrin Drabert, Helen G Gika, Evangelia Farmaki, John Dotis, Nikoleta Printza, Georgios A Theodoridis, Dimitrios Tsikas
Diminished Systemic Amino Acids Metabolome and Lipid Peroxidation in Ureteropelvic Junction Obstruction (UPJO) Infants Requiring Surgery. Journal of clinical medicine 10 (7) (2021)
Dimitrios Tsikas
Homocysteine and copper ions: is their interaction responsible for cardiovascular-related damage? Amino acids 53 (8) (2021)
Svetlana Baskal, Alexander Bollenbach, Catharina Mels, Ruan Kruger, Dimitrios Tsikas
Development, validation of a GC-MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special emphasis to lysine. Amino acids (2021)
Svetlana Baskal, Alexander Bollenbach, Dimitrios Tsikas
Two-Step Derivatization of Amino Acids for Stable-Isotope Dilution GC-MS Analysis: Long-Term Stability of Methyl Ester-Pentafluoropropionic Derivatives in Toluene Extracts. Molecules (Basel, Switzerland) 26 (6) (2021)
Kata Csekő, Dániel Pécsi, Béla Kajtár, Ivett Hegedűs, Alexander Bollenbach, Dimitrios Tsikas, Imre László Szabó, Sándor Szabó, Zsuzsanna Helyes
Upregulation of the TRPA1 Ion Channel in the Gastric Mucosa after Iodoacetamide-Induced Gastritis in Rats: A Potential New Therapeutic Target. International journal of molecular sciences 21 (16) (2020)
Folke Brinkmann, Beatrice Hanusch, Manfred Ballmann, Sebene Mayorandan, Alexander Bollenbach, Kristine Chobanyan-Jürgens, Kathrin Jansen, Anjona Schmidt-Choudhury, Nico Derichs, Dimitrios Tsikas, Thomas Lücke
Activated L-Arginine/Nitric Oxide Pathway in Pediatric Cystic Fibrosis and Its Association with Pancreatic Insufficiency, Liver Involvement and Nourishment: An Overview and New Results. Journal of clinical medicine 9 (6) (2020)
George T Kedia, Stefan Ückert, Dimitrios Tsikas, Armin J Becker, Markus A Kuczyk, Andreas Bannowsky
The Use of Vasoactive Drugs in the Treatment of Male Erectile Dysfunction: Current Concepts. Journal of clinical medicine 9 (9) (2020)
Alexander Bollenbach, Aletta Elisabeth Schutte, Ruan Kruger, Dimitrios Tsikas
An Ethnic Comparison of Arginine Dimethylation and Cardiometabolic Factors in Healthy Black and White Youth: The ASOS and African-PREDICT Studies. Journal of clinical medicine 9 (3) (2020)
Beatrice Hanusch, Folke Brinkmann, Sebene Mayorandan, Kristine Chobanyan-Jürgens, Anna Wiemers, Kathrin Jansen, Manfred Ballmann, Anjona Schmidt-Choudhury, Alexander Bollenbach, Nico Derichs, Dimitrios Tsikas, Thomas Lücke
Local and Systemic Alterations of the L-Arginine/Nitric Oxide Pathway in Sputum, Blood, and Urine of Pediatric Cystic Fibrosis Patients and Effects of Antibiotic Treatment. Journal of clinical medicine 9 (12) (2020)
Josefine Nebl, Kathrin Drabert, Sven Haufe, Paulina Wasserfurth, Julian Eigendorf, Uwe Tegtbur, Andreas Hahn, Dimitrios Tsikas
Exercise-Induced Oxidative Stress, Nitric Oxide and Plasma Amino Acid Profile in Recreational Runners with Vegetarian and Non-Vegetarian Dietary Patterns. Nutrients 11 (8) (2019)
Harrina E Rahardjo, Stefan Ückert, Dimitrios Tsikas, Petter Hedlund, Andreas Bannowsky, Markus A Kuczyk, George T Kedia
Arginase enzymes in the human prostate: A molecular biological and immunohistochemical approach. Andrologia 51 (9) (2019)
Alexander Bollenbach, Dimitrios Tsikas, Sigurd Lenzen, Anne Jörns
Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy. Amino acids 52 (1) (2019)
Dimitrios Tsikas, Alexander Bollenbach, Erik Hanff, Bibiana Beckmann, Björn Redfors
Synthesis of homoagmatine and GC-MS analysis of tissue homoagmatine and agmatine: evidence that homoagmatine but not agmatine is a metabolite of pharmacological L-homoarginine in the anesthetized rat. Amino acids 52 (2) (2019)
Adrian Post, M Yusof Said, Antonio W Gomes-Neto, Jennifer van der Krogt, Pim de Blaauw, Stefan P Berger, Johanna Marianna Geleijnse, Karin J Borgonjen-van den Berg, Else van den Berg, Harry Van Goor, Gerald Rimbach, Ido P Kema, Dimitrios Tsikas, M Rebecca Heiner-Fokkema, Stephan J L Bakker
Urinary Taurine Excretion and Risk of Late Graft Failure in Renal Transplant Recipients. Nutrients 11 (9) (2019)
Harrina E Rahardjo, Stefan Ückert, Andreas Bannowsky, Dimitrios Tsikas, Armin J Becker, Markus A Kuczyk
Course of transforming growth factor ß1 in the systemic and cavernous blood of healthy males through different penile conditions. Andrologia 51 (1) (2018)
P Shahin, H E Rahardjo, A Bannowsky, Dimitrios Tsikas, M Sohn, M A Kuczyk, Stefan Ückert
Endopeptidase inhibition attenuates the contraction induced by big endothelin-1 of isolated human penile erectile tissue. Andrologia 50 (5) (2018)
Darko Modun, Daniela Giustarini, Dimitrios Tsikas
Nitric oxide-related oxidative stress and redox status in health and disease. Oxidative medicine and cellular longevity 2014 (2014)
Arne Trettin, Anke Böhmer, Maria-Theresia Suchy, Irmelin Probst, Ulrich Staerk, Dirk O Stichtenoth, Jürgen C Frölich, Dimitrios Tsikas
Effects of paracetamol on NOS, COX, and CYP activity and on oxidative stress in healthy male subjects, rat hepatocytes, and recombinant NOS. Oxidative medicine and cellular longevity 2014 (2014)