Fergal Joseph O'Brien (Fergal J O'Brien, F J O'Brien, Fergal J O' Brien)

ResearcherID Scopus Author ID Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Venues

Advanced healthcare materials

Molecular pharmaceutics

Pharmaceutics

Nature reviews. Urology

Royal College of Surgeons in Ireland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Royal College of Surgeons in Ireland Aug 01 2019

Ireland

Director of Research and Innovation :: Office of Research and Innovation

Royal College of Surgeons in Ireland

Ireland

Professor :: Anatomy

Advanced Materials and BioEngineering Research (AMBER) Centre

Ireland

PI and Deputy Director

Trinity College Dublin, Centre for Bioengineering

Ireland

Adjunct Professor

Royal College of Surgeons in Ireland

Ireland

Head of Tissue Engineering Research Group :: Anatomy

Royal College of Surgeons in Ireland - Aug 31 2019

Ireland

Deputy Director for Research (Applied Research)

Publications

Nadia Pang, Ashang L Laiva, Noof Z Sulaiman, Priya Das, Fergal Joseph O'Brien, Michael B Keogh
Dual Glyoxalase-1 and β-Klotho Gene-Activated Scaffold Reduces Methylglyoxal and Reprograms Diabetic Adipose-Derived Stem Cells: Prospects in Improved Wound Healing. Pharmaceutics 16 (2) (2024)
Pádraig Carroll, Éimear Smith, Adrian Dervan, Ciarán McCarthy, Ian Woods, Cliff Beirne, Geoff Harte, Dónal O'Flynn, John F Quinlan, Fergal Joseph O'Brien, Michelle Flood, Frank Moriarty
The Development of Principles for Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: A Modified Delphi Study. Health expectations : an international journal of public participation in health care and health policy 27 (4) (2024)
Rosanne M Raftery, Arlyng G Gonzalez Vazquez, David P Walsh, Gang Chen, Ashang L Laiva, Michael B Keogh, Fergal Joseph O'Brien
Mobilizing Endogenous Progenitor Cells Using pSDF1α-Activated Scaffolds Accelerates Angiogenesis and Bone Repair in Critical-Sized Bone Defects. Advanced healthcare materials (2024)
Nadia Pang, Ashang L Laiva, Noof Z Sulaiman, Priya Das, Fergal Joseph O'Brien, Michael B Keogh
Dual Glyoxalase-1 and β-Klotho Gene-Activated Scaffold Reduces Methylglyoxal and Reprograms Diabetic Adipose-Derived Stem Cells: Prospects in Improved Wound Healing. Pharmaceutics 16 (2) (2024)
Pádraig Carroll, Éimear Smith, Adrian Dervan, Ciarán McCarthy, Ian Woods, Cliff Beirne, Geoff Harte, Dónal O'Flynn, John F Quinlan, Fergal Joseph O'Brien, Michelle Flood, Frank Moriarty
The Development of Principles for Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: A Modified Delphi Study. Health expectations : an international journal of public participation in health care and health policy 27 (4) (2024)
Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal Joseph O'Brien, Sally-Ann Cryan
Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications. Molecular pharmaceutics 21 (4) (2024)
Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal Joseph O'Brien, Sally-Ann Cryan
Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications. Molecular pharmaceutics 21 (4) (2024)
Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal Joseph O'Brien, Sally-Ann Cryan
Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications. Molecular pharmaceutics 21 (4) (2024)
Rosanne M Raftery, Arlyng G Gonzalez Vazquez, David P Walsh, Gang Chen, Ashang L Laiva, Michael B Keogh, Fergal Joseph O'Brien
Mobilizing Endogenous Progenitor Cells Using pSDF1α-Activated Scaffolds Accelerates Angiogenesis and Bone Repair in Critical-Sized Bone Defects. Advanced healthcare materials (2024)
Stefanie M Croghan, Eoghan M Cunnane, Sorcha O'Meara, Connor V Cunnane, James C Forde, Rustom P Manecksha, Michael T Walsh, Kieran J Breen, Barry B McGuire, Fergal Joseph O'Brien, Niall Francis Davis
Human in vivo baseline intrarenal pressure, peristaltic activity and response to ureteric stenting. BJU international (2024)
Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal Joseph O'Brien, Sally-Ann Cryan
Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications. Molecular pharmaceutics 21 (4) (2024)
Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal Joseph O'Brien, Sally-Ann Cryan
Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications. Molecular pharmaceutics (2024)
Donagh G O'Shea, Tom Hodgkinson, Caroline M Curtin, Fergal Joseph O'Brien
An injectable and 3D printable pro-chondrogenic hyaluronic acid and collagen type II composite hydrogel for the repair of articular cartilage defects. Biofabrication (2023)
Sorcha O'Meara, Eoghan M Cunnane, Stefanie M Croghan, Connor V Cunnane, Michael T Walsh, Fergal Joseph O'Brien, Niall F Davis
Mechanical characteristics of the ureter and clinical implications. Nature reviews. Urology 21 (4) (2023)
Sorcha O'Meara, Eoghan M Cunnane, Stefanie M Croghan, Connor V Cunnane, Michael T Walsh, Fergal Joseph O'Brien, Niall F Davis
Mechanical characteristics of the ureter and clinical implications. Nature reviews. Urology (2023)
Sorcha O'Meara, Stefanie M Croghan, Fergal Joseph O'Brien, Niall Francis Davis
A Good Craftsperson Knows Their Tools: Understanding of Laser and Ureter Mechanics in Training Urologists. Journal of lasers in medical sciences 14 (2023)
Giuseppe A Asaro, Matteo Solazzo, Meenakshi Suku, Dahnan Spurling, Katelyn Genoud, Javier Gutierrez Gonzalez, Fergal Joseph O'Brien, Valeria Nicolosi, Michael G Monaghan
MXene functionalized collagen biomaterials for cardiac tissue engineering driving iPSC-derived cardiomyocyte maturation. NPJ 2D materials and applications 7 (1) (2023)
Sorcha O'Meara, Eoghan M Cunnane, Stefanie M Croghan, Connor V Cunnane, Michael T Walsh, Fergal Joseph O'Brien, Niall F Davis
Mechanical characteristics of the ureter and clinical implications. Nature reviews. Urology 21 (4) (2023)
Sorcha O'Meara, Eoghan M Cunnane, Stefanie M Croghan, Connor V Cunnane, Michael T Walsh, Fergal Joseph O'Brien, Niall F Davis
Mechanical characteristics of the ureter and clinical implications. Nature reviews. Urology 21 (4) (2023)
Giuseppe A Asaro, Matteo Solazzo, Meenakshi Suku, Dahnan Spurling, Katelyn Genoud, Javier Gutierrez Gonzalez, Fergal Joseph O'Brien, Valeria Nicolosi, Michael G Monaghan
MXene functionalized collagen biomaterials for cardiac tissue engineering driving iPSC-derived cardiomyocyte maturation. NPJ 2D materials and applications 7 (1) (2023)
Joanna Maria Sadowska, Rachael N Power, Katelyn J Genoud, Austyn Matheson, Arlyng González-Vázquez, Lara Costard, Kian Eccholz, Pierluca Pitacco, Tanguy Hallegouet, Gang Chen, Caroline M Curtin, Ciara M Murphy, Brenton Cavanagh, Huijun Zhang, Daniel J Kelly, Aldo R Boccaccini, Fergal Joseph O'Brien
A multifunctional scaffold for bone infection treatment by delivery of microRNA therapeutics combined with antimicrobial nanoparticles. Advanced materials (Deerfield Beach, Fla.) (2023)
Matthew McGrath, Karolina Zimkowska, Katelyn J Genoud, Jack Maughan, Javier Gutierrez Gonzalez, Shane Browne, Fergal Joseph O'Brien
A Biomimetic, Bilayered Antimicrobial Collagen-Based Scaffold for Enhanced Healing of Complex Wound Conditions. ACS applied materials & interfaces (2023)
Claudio Intini, Tom Hodgkinson, Sarah M Casey, John P Gleeson, Fergal Joseph O'Brien
Highly Porous Type II Collagen-Containing Scaffolds for Enhanced Cartilage Repair with Reduced Hypertrophic Cartilage Formation. Bioengineering (Basel, Switzerland) 9 (6) (2022)
Rachael N Power, Brenton L Cavanagh, James E Dixon, Caroline M Curtin, Fergal Joseph O'Brien
Development of a Gene-Activated Scaffold Incorporating Multifunctional Cell-Penetrating Peptides for pSDF-1α Delivery for Enhanced Angiogenesis in Tissue Engineering Applications. International journal of molecular sciences 23 (3) (2022)
Pádraig Carroll, Adrian Dervan, Anthony Maher, Ciarán McCarthy, Ian Woods, Rachel Kavanagh, Cliff Beirne, Geoff Harte, Dónal O'Flynn, Cian O'Connor, Tara McGuire, Liam M Leahy, Javier Gutierrez Gonzalez, Martyna Stasiewicz, Jack Maughan, Pedro Jose Gouveia, Paul J Murphy, John F Quinlan, Sarah Casey, Alice Holton, Éimear Smith, Frank Moriarty, Fergal Joseph O'Brien, Michelle Flood
Applying Patient and Public Involvement in preclinical research: A co-created scoping review. Health expectations : an international journal of public participation in health care and health policy 25 (6) (2022)
Robert T Brady, Fergal Joseph O'Brien, David A Hoey
The Impact of the Extracellular Matrix Environment on Sost Expression by the MLO-Y4 Osteocyte Cell Line. Bioengineering (Basel, Switzerland) 9 (1) (2022)
Fergal J O'Brien, Caroline M Curtin, Fergal Joseph O'Brien
Articulation inspired by nature: a review of biomimetic and biologically active 3D printed scaffolds for cartilage tissue engineering. Biomaterials science 10 (10) (2022)
Paige V Hinton, Katelyn J Genoud, James O Early, Fergal Joseph O'Brien, Oran D Kennedy
Impact of Fluid Flow Shear Stress on Osteoblast Differentiation and Cross-Talk with Articular Chondrocytes. International journal of molecular sciences 23 (16) (2022)
Tom Hodgkinson, Domhnall C Kelly, Caroline M Curtin, Fergal Joseph O'Brien
Mechanosignalling in cartilage: an emerging target for the treatment of osteoarthritis. Nature reviews. Rheumatology 18 (2) (2021)
Rita I R Ibañez, Ronaldo Jose Farias Correa Do Amaral, Rui L Reis, Alexandra P Marques, Ciara M Murphy, Fergal Joseph O'Brien
3D-Printed Gelatin Methacrylate Scaffolds with Controlled Architecture and Stiffness Modulate the Fibroblast Phenotype towards Dermal Regeneration. Polymers 13 (15) (2021)
Arlyng G Gonzalez Vazquez, Lia A Blokpoel Ferreras, Kathleen E Bennett, Sarah M Casey, Pieter Aj Brama, Fergal Joseph O'Brien
Systematic Comparison of Biomaterials-Based Strategies for Osteochondral and Chondral Repair in Large Animal Models. Advanced healthcare materials 10 (20) (2021)
Ian Woods, Cian O'Connor, Lisa Frugoli, Seán Kerr, Javier Gutierrez Gonzalez, Martyna Stasiewicz, Tara McGuire, Brenton L Cavanagh, Alan J Hibbitts, Adrian Dervan, Fergal Joseph O'Brien
Biomimetic Scaffolds for Spinal Cord Applications Exhibit Stiffness-Dependent Immunomodulatory and Neurotrophic Characteristics. Advanced healthcare materials (2021)
Ashang L Laiva, Fergal Joseph O'Brien, Michael B Keogh
Anti-Aging β-Klotho Gene-Activated Scaffold Promotes Rejuvenative Wound Healing Response in Human Adipose-Derived Stem Cells. Pharmaceuticals (Basel, Switzerland) 14 (11) (2021)
Luis Soriano, Tehreem Khalid, Fergal Joseph O'Brien, Cian O'Leary, Sally-Ann Cryan
A Tissue-Engineered Tracheobronchial In Vitro Co-Culture Model for Determining Epithelial Toxicological and Inflammatory Responses. Biomedicines 9 (6) (2021)
Tom Hodgkinson, P Monica Tsimbouri, Virginia Llopis-Hernandez, Paul Campsie, David J Scurr, Peter G Childs, David Phillips, Sam Donnelly, Julia A Wells, Fergal Joseph O'Brien, Manuel Salmeron-Sanchez, Karl Burgess, Morgan R Alexander, Massimo Vassalli, Richard O C Oreffo, Stuart Reid, David J France, Matthew John Dalby
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science advances 7 (9) (2021)
Ashang L Laiva, Fergal Joseph O'Brien, Michael B Keogh
SDF-1α Gene-Activated Collagen Scaffold Restores Pro-Angiogenic Wound Healing Features in Human Diabetic Adipose-Derived Stem Cells. Biomedicines 9 (2) (2021)
Adrian Dervan, Antonio Franchi, Francisco R Almeida-Gonzalez, Jennifer K Dowling, Ohemaa B Kwakyi, Claire E McCoy, Fergal Joseph O'Brien, Alan Hibbitts
Biomaterial and Therapeutic Approaches for the Manipulation of Macrophage Phenotype in Peripheral and Central Nerve Repair. Pharmaceutics 13 (12) (2021)
Rosanne M Raftery, Arlyng G Gonzalez Vazquez, Gang Chen, Fergal Joseph O'Brien
Activation of the SOX-5, SOX-6, and SOX-9 Trio of Transcription Factors Using a Gene-Activated Scaffold Stimulates Mesenchymal Stromal Cell Chondrogenesis and Inhibits Endochondral Ossification. Advanced healthcare materials 9 (10) (2020)
M Suku, A L Laiva, Fergal Joseph O'Brien, Michael B Keogh
Anti-Ageing Protein β-Klotho Rejuvenates Diabetic Stem Cells for Improved Gene-Activated Scaffold Based Wound Healing. Journal of personalized medicine 11 (1) (2020)
Rukmani Sridharan, Katelyn J Genoud, Daniel John Kelly, Fergal Joseph O'Brien
Hydroxyapatite Particle Shape and Size Influence MSC Osteogenesis by Directing the Macrophage Phenotype in Collagen-Hydroxyapatite Scaffolds. ACS applied bio materials 3 (11) (2020)
Lara S Costard, Domhnall C Kelly, Rachael N Power, Christopher Hobbs, Sonia Jaskaniec, Valeria Nicolosi, Brenton L Cavanagh, Caroline M Curtin, Fergal Joseph O'Brien
Layered Double Hydroxide as a Potent Non-viral Vector for Nucleic Acid Delivery Using Gene-Activated Scaffolds for Tissue Regeneration Applications. Pharmaceutics 12 (12) (2020)
Eoghan M Cunnane, Katherine L Lorentz, Aneesh K Ramaswamy, Prerak Gupta, Biman B Mandal, Fergal Joseph O'Brien, Justin S Weinbaum, David A Vorp
Extracellular Vesicles Enhance the Remodeling of Cell-Free Silk Vascular Scaffolds in Rat Aortae. ACS applied materials & interfaces 12 (24) (2020)
Matteo Solazzo, Fergal Joseph O'Brien, Valeria Nicolosi, Michael G Monaghan
The rationale and emergence of electroconductive biomaterial scaffolds in cardiac tissue engineering. APL bioengineering 3 (4) (2019)
Ronaldo Jose Farias Correa Do Amaral, Brenton Cavanagh, Fergal Joseph O'Brien, Cathal John Kearney
Platelet-derived growth factor stabilises vascularisation in collagen-glycosaminoglycan scaffolds in vitro. Journal of tissue engineering and regenerative medicine 13 (2) (2019)
Domhnall C Kelly, Rosanne M Raftery, Caroline M Curtin, Caitriona M O'Driscoll, Fergal Joseph O'Brien
Scaffold-Based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 37 (8) (2019)
Saltuk B Hanay, Joanne O'Dwyer, Scott D Kimmins, Fernando C S de Oliveira, Matthew G Haugh, Fergal Joseph O'Brien, Sally-Ann Cryan, Andreas Heise
Facile Approach to Covalent Copolypeptide Hydrogels and Hybrid Organohydrogels. ACS macro letters 7 (8) (2018)
David P Walsh, Robert D Murphy, Angela Panarella, Rosanne M Raftery, Brenton Cavanagh, Jeremy C Simpson, Fergal Joseph O'Brien, Andreas Heise, Sally-Ann Cryan
Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells. Molecular pharmaceutics 15 (5) (2018)
Rukmani Sridharan, Emily J Ryan, Cathal J Kearney, Daniel John Kelly, Fergal Joseph O'Brien
Macrophage Polarization in Response to Collagen Scaffold Stiffness Is Dependent on Cross-Linking Agent Used To Modulate the Stiffness. ACS biomaterials science & engineering 5 (2) (2018)
Alan J Ryan, Cathal J Kearney, Nian Shen, Umar Khan, Adam G Kelly, Christopher Probst, Eva Brauchle, Sonia Biccai, Carolina D Garciarena, Victor Vega-Mayoral, Peter Loskill, Steve W Kerrigan, Daniel J Kelly, Katja Schenke-Layland, Jonathan N Coleman, Fergal Joseph O'Brien
Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity. Advanced materials (Deerfield Beach, Fla.) 30 (15) (2018)
Amos Matsiko, Emmet M Thompson, Cai Lloyd-Griffith, Gráinne M Cunniffe, Tatiana Vinardell, John P Gleeson, Daniel John Kelly, Fergal Joseph O'Brien
An endochondral ossification approach to early stage bone repair: Use of tissue-engineered hypertrophic cartilage constructs as primordial templates for weight-bearing bone repair. Journal of tissue engineering and regenerative medicine 12 (4) (2018)
Filipa Lebre, Rukmani Sridharan, Michael J Sawkins, Daniel John Kelly, Fergal Joseph O'Brien, Ed C Lavelle
The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation. Scientific reports 7 (1) (2017)
Caroline M Curtin, Irene Mencía Castaño, Fergal Joseph O'Brien
Scaffold-Based microRNA Therapies in Regenerative Medicine and Cancer. Advanced healthcare materials 7 (1) (2017)
Claire M Brougham, Tanya J Levingstone, Nian Shen, Gerard M Cooney, Stefan Jockenhoevel, Thomas C Flanagan, Fergal Joseph O'Brien
Freeze-Drying as a Novel Biofabrication Method for Achieving a Controlled Microarchitecture within Large, Complex Natural Biomaterial Scaffolds. Advanced healthcare materials 6 (21) (2017)
Sara Barreto, Arlyng G Gonzalez Vazquez, Andrew R Cameron, Fergal Joseph O'Brien, Dylan J Murray
Identification of stiffness-induced signalling mechanisms in cells from patent and fused sutures associated with craniosynostosis. Scientific reports 7 (1) (2017)
Henrique V Almeida, Anna D Dikina, Kevin J Mulhall, Fergal Joseph O'Brien, Eben Alsberg, Daniel John Kelly
Porous Scaffolds Derived from Devitalized Tissue Engineered Cartilaginous Matrix Support Chondrogenesis of Adult Stem Cells. ACS biomaterials science & engineering 3 (6) (2017)
Cian O'Leary, Fergal Joseph O'Brien, Sally-Ann Cryan
Retinoic Acid-Loaded Collagen-Hyaluronate Scaffolds: A Bioactive Material for Respiratory Tissue Regeneration. ACS biomaterials science & engineering 3 (7) (2017)
Ashang Luwang Laiva, Fergal Joseph O'Brien, Michael B Keogh
Innovations in gene and growth factor delivery systems for diabetic wound healing. Journal of tissue engineering and regenerative medicine 12 (1) (2017)

Fergal Joseph O'Brien.css-eqlu8i{font-size:small;padding-left:4px;} (Fergal J O'Brien, F J O'Brien, Fergal J O' Brien)

Publication Activity (10 Years)

Top Topics

Top Venues

Fergal Joseph O'Brien (Fergal J O'Brien, F J O'Brien, Fergal J O' Brien)