Richard O C Oreffo (Richard Oreffo, Richard Oc Oreffo, R O C Oreffo)

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 36

Top Venues

Nature communications

Scientific reports

Bio-design and manufacturing

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

University of Southampton

University of Liverpool (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Southampton

United Kingdom

Personal Chair in Musculoskeletal Science

University of Southampton

United Kingdom

Associate Dean International and Enterprise

University of Southampton

United Kingdom

Director of Enterprise :: Faculty of Medicine, Health and Life Sciences

University of Southampton

United Kingdom

Associate Dean ( Innovation and Enterprise) :: Faculty of Medicine, Health and Life Sciences

University of Southampton

United Kingdom

Reader

University of Southampton

United Kingdom

Senior lecturer

University of Southampton

United Kingdom

Non-Clinical lecturer

University of Oxford

United Kingdom

MRC Research Fellow

Zeneca Pharmaceuticals

United Kingdom

Principal Research Scientist

Zeneca Pharmaceuticals

United Kingdom

Postdoctoral Research Fellow

University of Texas at San Antonio

United States

Research Fellow :: Department of Medicine

Oxford Brookes University

United Kingdom

Demonstrator

Education History

University of Liverpool

United Kingdom

BSC :: Biochemistry

Publications

Yang-Hee Kim, Janos M Kanczler, Stuart Lanham, Andrew Rawlings, Marta Roldo, Gianluca Tozzi, Jonathan I Dawson, Gianluca Cidonio, Richard O C Oreffo
Biofabrication of nanocomposite-based scaffolds containing human bone extracellular matrix for the differentiation of skeletal stem and progenitor cells. Bio-design and manufacturing 7 (2) (2024)
Takahiro Onoki, Janos M Kanczler, Andrew Rawlings, Melanie Smith, Yang-Hee Kim, Ko Hashimoto, Toshimi Aizawa, Richard O C Oreffo
Modulation of osteoblastogenesis by NRF2: NRF2 activation suppresses osteogenic differentiation and enhances mineralization in human bone marrow-derived mesenchymal stromal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (17) (2024)
Yang-Hee Kim, Janos M Kanczler, Stuart Lanham, Andrew Rawlings, Marta Roldo, Gianluca Tozzi, Jonathan I Dawson, Gianluca Cidonio, Richard O C Oreffo
Biofabrication of nanocomposite-based scaffolds containing human bone extracellular matrix for the differentiation of skeletal stem and progenitor cells. Bio-design and manufacturing 7 (2) (2024)
Yang-Hee Kim, Janos M Kanczler, Stuart Lanham, Andrew Rawlings, Marta Roldo, Gianluca Tozzi, Jonathan I Dawson, Gianluca Cidonio, Richard O C Oreffo
Biofabrication of nanocomposite-based scaffolds containing human bone extracellular matrix for the differentiation of skeletal stem and progenitor cells. Bio-design and manufacturing 7 (2) (2024)
Takahiro Onoki, Janos M Kanczler, Andrew Rawlings, Melanie Smith, Yang-Hee Kim, Ko Hashimoto, Toshimi Aizawa, Richard O C Oreffo
Modulation of osteoblastogenesis by NRF2: NRF2 activation suppresses osteogenic differentiation and enhances mineralization in human bone marrow-derived mesenchymal stromal cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (17) (2024)
Ewan A Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Penelope M Tsimbouri, Karl V Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A G Oliva, Jennifer Willis, Jaspreet Bansal, Paul M Reynolds, Julia A Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O C Oreffo, Manuel Salmeron-Sanchez, Matthew John Dalby
Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature communications 14 (1) (2023)
Roxanna Sharon Ramnarine-Sanchez, Janos M Kanczler, Nicholas D Evans, Richard O C Oreffo, Jonathan I Dawson
Self-assembly of Structured Colloidal Gels for High Resolution 3d Micropatterning of Proteins at Scale. Advanced materials (Deerfield Beach, Fla.) (2023)
Ewan A Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Penelope M Tsimbouri, Karl V Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A G Oliva, Jennifer Willis, Jaspreet Bansal, Paul M Reynolds, Julia A Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O C Oreffo, Manuel Salmeron-Sanchez, Matthew John Dalby
Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature communications 14 (1) (2023)
Ewan A Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Penelope M Tsimbouri, Karl V Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A G Oliva, Jennifer Willis, Jaspreet Bansal, Paul M Reynolds, Julia A Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O C Oreffo, Manuel Salmeron-Sanchez, Matthew John Dalby
Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature communications 14 (1) (2023)
Ewan A Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Penelope M Tsimbouri, Karl V Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A G Oliva, Jennifer Willis, Jaspreet Bansal, Paul M Reynolds, Julia A Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O C Oreffo, Manuel Salmeron-Sanchez, Matthew John Dalby
Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature communications 14 (1) (2023)
Ewan A Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Penelope M Tsimbouri, Karl V Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A G Oliva, Jennifer Willis, Jaspreet Bansal, Paul M Reynolds, Julia A Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O C Oreffo, Manuel Salmeron-Sanchez, Matthew John Dalby
Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature communications 14 (1) (2023)
Yang-Hee Kim, Jonathan I Dawson, Richard O C Oreffo, Yasuhiko Tabata, Dhiraj Kumar, Conrado Aparicio, Isha Mutreja
Gelatin Methacryloyl Hydrogels for Musculoskeletal Tissue Regeneration. Bioengineering (Basel, Switzerland) 9 (7) (2022)
Cameron Black, David Gibbs, Josephine McEwan, Janos M Kanczler, Marta Peña Fernández, Gianluca Tozzi, Jonathan Dawson, Richard O C Oreffo
Comparison of bone formation mediated by bone morphogenetic protein delivered by nanoclay gels with clinical techniques (autograft and InductOs ® ) in an ovine bone model. Journal of tissue engineering 13 (2022)
Katherine A Williams, Neil J Gostling, Richard O C Oreffo, Philipp Schneider
Ontogenetic changes in cortical bone vascular microstructure in the domestic duck (Anas platyrhynchos) and ring-necked pheasant (Phasianus colchicus). Journal of anatomy 241 (6) (2022)
Vitali Goriainov, Leonard J King, Richard O C Oreffo, Douglas G Dunlop
Custom 3D-Printed Triflange Implants for Treatment of Severe Acetabular Defects, with and without Pelvic Discontinuity: Early Results of Our First 19 Consecutive Cases. JB & JS open access 6 (4) (2021)
Babatunde O Okesola, Ana Karen Mendoza-Martinez, Gianluca Cidonio, Burak Derkus, Delali K Boccorh, David Osuna de la Peña, Sherif Elsharkawy, Yuanhao Wu, Jonathan I Dawson, Alastair W Wark, Dafna Knani, Dave J Adams, Richard O C Oreffo, Alvaro Mata
De Novo Design of Functional Coassembling Organic-Inorganic Hydrogels for Hierarchical Mineralization and Neovascularization. ACS nano (2021)
Mohamed Mousa, Juan Aviles Milan, Oscar Kelly, Jane Doyle, Nicholas D Evans, Richard O C Oreffo, Jonathan I Dawson
The role of lithium in the osteogenic bioactivity of clay nanoparticles. Biomaterials science 9 (8) (2021)
Pooja Basnett, Rupy K Matharu, Caroline S Taylor, Upulitha Illangakoon, Jonathan I Dawson, Janos M Kanczler, Mehrie Behbehani, Eleanor Humphrey, Qasim Majid, Barbara Lukasiewicz, Rinat Nigmatullin, Phoebe Louiseanne Heseltine, Richard O C Oreffo, John W Haycock, Cesare Terracciano, Sian E Harding, Mohan Edirisinghe, Ipsita Roy
Harnessing Polyhydroxyalkanoates and Pressurized Gyration for Hard and Soft Tissue Engineering. ACS applied materials & interfaces 13 (28) (2021)
Hareklea Markides, Nicola C Foster, Jane S McLaren, Timothy Hopkins, Cameron Black, Richard O C Oreffo, Brigitte E Scammell, Iria Echevarria, Lisa Jane White, Alicia J El Haj
Short-Term Evaluation of Cellular Fate in an Ovine Bone Formation Model. Cells 10 (7) (2021)
James P K Armstrong, Timothy J Keane, Anne C Roques, P Stephen Patrick, Claire M Mooney, Wei-Li Kuan, Venkat Pisupati, Richard O C Oreffo, Daniel J Stuckey, Fiona M Watt, Stuart John Forbes, Roger A Barker, Molly M Stevens
A blueprint for translational regenerative medicine. Science translational medicine 12 (572) (2021)
Tom Hodgkinson, P Monica Tsimbouri, Virginia Llopis-Hernandez, Paul Campsie, David J Scurr, Peter G Childs, David Phillips, Sam Donnelly, Julia A Wells, Fergal Joseph O'Brien, Manuel Salmeron-Sanchez, Karl Burgess, Morgan R Alexander, Massimo Vassalli, Richard O C Oreffo, Stuart Reid, David J France, Matthew John Dalby
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science advances 7 (9) (2021)
Yuanhao Wu, Babatunde O Okesola, Jing Xu, Ivan Korotkin, Alice Berardo, Ilaria Corridori, Francesco Luigi Pellerej di Brocchetti, Janos Kanczler, Jingyu Feng, Weiqi Li, Yejiao Shi, Vladimir S Farafonov, Yiqiang Wang, Rebecca F Thompson, Maria-Magdalena Titirci, Dmitry A Nerukh, Sergey Karabasov, Richard O C Oreffo, Jose Carlos Rodriguez-Cabello, Giovanni Vozzi, Helena S Azevedo, Nicola Maria Pugno, Wen Wang, Alvaro Mata
Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices. Nature communications 11 (1) (2020)
María C de Andrés, Mia S Meiss, Marina Sánchez-Hidalgo, Alejandro González-Benjumea, Jose G Fernández-Bolaños, Catalina Alarcón-de-la-Lastra, Richard O C Oreffo
Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol. Journal of tissue engineering 11 (2020)
Katherine A Williams, Neil J Gostling, Joshua W Steer, Richard O C Oreffo, Philipp Schneider
Quantifying intracortical bone microstructure: A critical appraisal of 2D and 3D approaches for assessing vascular canals and osteocyte lacunae. Journal of anatomy (2020)
Yang-Hee Kim, Xia Yang, Liyang Shi, Stuart A Lanham, Jons Hilborn, Richard O C Oreffo, Dmitri A Ossipov, Jonathan I Dawson
Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization. Nature communications 11 (1) (2020)
Marta Peña Fernández, Cameron Black, Jon Dawson, David Gibbs, Janos Kanczler, Richard O C Oreffo, Gianluca Tozzi
Exploratory Full-Field Strain Analysis of Regenerated Bone Tissue from Osteoinductive Biomaterials. Materials (Basel, Switzerland) 13 (1) (2020)
Patrick S Stumpf, Xin Du, Haruka Imanishi, Yuya Kunisaki, Yuichiro Semba, Timothy Noble, Rosanna C G Smith, Matthew Rose-Zerili, Jonathan J West, Richard O C Oreffo, Katayoun Farrahi, Mahesan Niranjan, Koichi Akashi, Fumio Arai, Ben D MacArthur
Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing. Communications biology 3 (1) (2020)
Inés Moreno-Jiménez, Stuart A Lanham, Janos M Kanczler, Gry Hulsart-Billstrom, Nicholas D Evans, Richard O C Oreffo
Remodelling of human bone on the chorioallantoic membrane of the chicken egg: De novo bone formation and resorption. Journal of tissue engineering and regenerative medicine 12 (8) (2019)
Catarina Costa Moura, Stuart A Lanham, Tual Monfort, Konstantinos N Bourdakos, Rahul S Tare, Richard O C Oreffo, Sumeet Mahajan
Quantitative temporal interrogation in 3D of bioengineered human cartilage using multimodal label-free imaging. Integrative biology : quantitative biosciences from nano to macro 10 (10) (2019)
Catarina Costa Moura, Konstantinos N Bourdakos, Rahul S Tare, Richard O C Oreffo, Sumeet Mahajan
Live-imaging of Bioengineered Cartilage Tissue using Multimodal Non-linear Molecular Imaging. Scientific reports 9 (1) (2019)
Stefanie Inglis, Karl Heinrich Schneider, Janos M Kanczler, Heinz Redl, Richard O C Oreffo
Harnessing Human Decellularized Blood Vessel Matrices and Cellular Construct Implants to Promote Bone Healing in an Ex Vivo Organotypic Bone Defect Model. Advanced healthcare materials 8 (9) (2018)
Miguel Xavier, María C de Andrés, Daniel Spencer, Richard O C Oreffo, Hywel Morgan
Size and dielectric properties of skeletal stem cells change critically after enrichment and expansion from human bone marrow: consequences for microfluidic cell sorting. Journal of the Royal Society, Interface 14 (133) (2018)
Isabel R Orriss, Stuart Lanham, Dawn Savery, Nicholas D E Greene, Philip Stanier, Richard O C Oreffo, Andrew J Copp, Gabriel L Galea
Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice. Scientific reports 8 (1) (2018)
Stuart A Lanham, F R Cagampang, Richard O C Oreffo
The influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice. Scientific reports 8 (1) (2018)
Atsushi Takahashi, María C de Andrés, Ko Hashimoto, Eiji Itoi, Miguel Otero, Kenneth B Marcu, Richard O C Oreffo
DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes. Scientific reports 7 (1) (2017)
Justyna P Smus, Catarina Costa Moura, Emma McMorrow, Rahul S Tare, Richard O C Oreffo, Sumeet Mahajan
Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging. Chemical science 6 (12) (2015)

Richard O C Oreffo.css-eqlu8i{font-size:small;padding-left:4px;} (Richard Oreffo, Richard Oc Oreffo, R O C Oreffo)

Publication Activity (10 Years)

Top Topics

Top Venues

Richard O C Oreffo (Richard Oreffo, Richard Oc Oreffo, R O C Oreffo)