Filip Van Petegem (Filip van Petegem)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 17

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

The Journal of general physiology

Nature chemical biology

University of British Columbia

Ghent University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of British Columbia Jul 01 2017

Canada

Professor :: Biochemistry and Molecular Biology

University of British Columbia Jul 01 2012 - Jun 30 2017

Canada

Associate Professor :: Biochemistry and Molecular Biology

University of British Columbia Jul 01 2007 - Jun 30 2012

Canada

Assistant Professor :: Biochemistry and Molecular Biology

University of California San Francisco Nov 01 2002 - May 31 2007

United States

Postdoctoral fellow :: Cardiovascular Research Institute

Education History

Ghent University Oct 01 1998 - Sep 15 2002

Belgium

PHD :: Biochemistry, physiology and Microbiology

Ghent University Oct 01 1994 - Jun 30 1998

Belgium

BSC :: Biochemistry, physiology and microbiology

Publications

Rita de Cássia Collaço, Filip Van Petegem, Frank Bosmans
ω-Grammotoxin-SIA inhibits voltage-gated Na+ channel currents. The Journal of general physiology 156 (10) (2024)
Omid Haji-Ghassemi, Yu Seby Chen, Kellie Woll, Georgina B Gurrola, Carmen R Valdivia, Wenxuan Cai, Songhua Li, Héctor H Valdivia, Filip Van Petegem
Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation. Science advances 9 (21) (2023)
Katrien Willegems, Jodene Eldstrom, Efthimios Kyriakis, Fariba Ataei, Harutyun Sahakyan, Ying Dou, Sophia Russo, Filip Van Petegem, David Fedida
Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nature communications 13 (1) (2022)
Zheng Fang Yang, Pankaj Panwar, Ciaran R McFarlane, Wietske E Tuinte, Marta Campiglio, Filip Van Petegem
Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations. Proceedings of the National Academy of Sciences of the United States of America 119 (10) (2022)
Kellie A Woll, Omid Haji-Ghassemi, Filip Van Petegem
Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nature communications 12 (1) (2021)
Parisa Asghari, David R L Scriven, Myles Ng, Pankaj Panwar, Keng C Chou, Filip Van Petegem, Edwin D W Moore
Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification. eLife 9 (2020)
Ruifang Ma, Omid Haji-Ghassemi, Dan Ma, Heng Jiang, Lianyun Lin, Li Yao, Arthur Samurkas, Yuxin Li, Yiwen Wang, Peng Cao, Shian Wu, Yan Zhang, Takashi Murayama, Bernard Moussian, Filip Van Petegem, Zhiguang Yuchi
Structural basis for diamide modulation of ryanodine receptor. Nature chemical biology 16 (11) (2020)
Kaiqian Wang, Malene Brohus, Christian Holt, Michael Toft Overgaard, Reinhard Wimmer, Filip Van Petegem
Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+ binding and cause misfolding. The Journal of physiology 598 (6) (2020)
Guillaume Déjean, Kazune Tamura, Adriana Cabrera, Namrata Jain, Nicholas A Pudlo, Gabriel Pereira, Alexander Holm Viborg, Filip Van Petegem, Eric C Martens, Harry Brumer
Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides. mBio 11 (2) (2020)
Matthew K Y Tung, Filip Van Petegem, Samantha Lauson, Ashley Collier, Kathy Hodgkinson, Bridget Fernandez, Sean Connors, Rick Leather, Shubhayan Sanatani, Laura Arbour
Cardiac arrest in a mother and daughter and the identification of a novel RYR2 variant, predisposing to low penetrant catecholaminergic polymorphic ventricular tachycardia in a four-generation Canadian family. Molecular genetics & genomic medicine 8 (4) (2020)
Sanam Shafaattalab, Alison Yueh Li, Eric Lin, Charles M Stevens, Laura J Dewar, Francis C Lynn, Shubhayan Sanatani, Zachary W M Laksman, Ryan D Morin, Filip Van Petegem, Leif Hove-Madsen, D Peter Tieleman, Jonathan P Davis, Glen F Tibbits
In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants. Proceedings of the National Academy of Sciences of the United States of America 116 (14) (2019)
Bernd R Gardill, Ricardo E Rivera-Acevedo, Ching-Chieh Tung, Filip Van Petegem
Crystal structures of Ca2+-calmodulin bound to NaV C-terminal regions suggest role for EF-hand domain in binding and inactivation. Proceedings of the National Academy of Sciences of the United States of America 116 (22) (2019)
Leo C T Ng, Meiying Zhuang, Filip Van Petegem, Yue Xian Li, Eric A Accili
Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide-gated ion channel. The Journal of general physiology 151 (10) (2019)
Filip Van Petegem, Bernd R Gardill
Reply to Pitt and Lee: Occupancies of Ca2+ in complexes of calmodulin with voltage-gated sodium channels. Proceedings of the National Academy of Sciences of the United States of America (2019)
Marta Campiglio, Pierre Costé de Bagneaux, Nadine J Ortner, Petronel Tuluc, Filip Van Petegem, Bernhard E Flucher
STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation. Proceedings of the National Academy of Sciences of the United States of America 115 (6) (2018)
Siobhan M Wong King Yuen, Marta Campiglio, Ching-Chieh Tung, Bernhard E Flucher, Filip Van Petegem
Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proceedings of the National Academy of Sciences of the United States of America 114 (45) (2017)
Mads Toft Søndergaard, Yingjie Liu, Kamilla Taunsig Larsen, Alma Nani, Xixi Tian, Christian Holt, Ruiwu Wang, Reinhard Wimmer, Filip Van Petegem, Michael Fill, S R Wayne Chen, Michael Toft Overgaard
The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. The Journal of biological chemistry 292 (4) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Filip Van Petegem (Filip van Petegem)