George-Lucian Moldovan

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 26

Top Venues

Nature communications

Nucleic acids research

NAR cancer

Oncogene

Penn State College of Medicine

Max-Planck-Institut für Biochemie (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Penn State College of Medicine Jul 01 2018

United States

Associate Professor :: Biochemistry

Penn State College of Medicine - Jun 30 2018

United States

Assistant Professor :: Biochemistry

Dana Farber Cancer Institute

United States

Postdoctoral fellow :: Radiation Oncology

Education History

Max-Planck-Institut für Biochemie

Germany

PHD :: Molecular and Cellular Biology

Universitatea din Bucure?ti

Romania

BSC :: Biochemistry

Publications

Jude B Khatib, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M Nicolae
PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis. Nature communications 15 (1) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research 52 (5) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research 52 (5) (2024)
Jude B Khatib, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M Nicolae
PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis. Nature communications 15 (1) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research 52 (5) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research (2024)
Jude B Khatib, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M Nicolae
PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis. Nature communications 15 (1) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research 52 (5) (2024)
Alexandra Nusawardhana, Lindsey M Pale, Claudia M Nicolae, George-Lucian Moldovan
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. Nucleic acids research 52 (5) (2024)
Anastasia Hale, Ashna Dhoonmoon, Joshua Straka, Claudia M Nicolae, George-Lucian Moldovan
Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases. Nature communications 14 (1) (2023)
Lindsey M Jackson, George-Lucian Moldovan
Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment. NAR cancer 4 (4) (2022)
Emily M Schleicher, Ashna Dhoonmoon, Lindsey M Jackson, Jude B Khatib, Claudia M Nicolae, George-Lucian Moldovan
The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells. Oncogenesis 11 (1) (2022)
Ashna Dhoonmoon, Claudia M Nicolae, George-Lucian Moldovan
The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1. Nature communications 13 (1) (2022)
Lindsey M Jackson, George-Lucian Moldovan
Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment. NAR cancer 4 (4) (2022)
Lindsey M Jackson, George-Lucian Moldovan
Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment. NAR cancer 4 (4) (2022)
Tanay Thakar, Ashna Dhoonmoon, Joshua Straka, Emily M Schleicher, Claudia M Nicolae, George-Lucian Moldovan
Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling. Nature communications 13 (1) (2022)
Tanay Thakar, George-Lucian Moldovan
The emerging determinants of replication fork stability. Nucleic acids research 49 (13) (2021)
Emily M Schleicher, George-Lucian Moldovan
CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery. The FEBS journal (2021)
Arindam Datta, Kajal Biswas, Joshua A Sommers, Haley Thompson, Sanket Awate, Claudia M Nicolae, Tanay Thakar, George-Lucian Moldovan, Robert H Shoemaker, Shyam K Sharan, Robert M Brosh
WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells. Nature communications 12 (1) (2021)
Lindsey M Jackson, Ashna Dhoonmoon, Anastasia Hale, Kady A Dennis, Emily M Schleicher, Claudia M Nicolae, George-Lucian Moldovan
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells. Nucleic acids research (2021)
Michael J O'Connor, Tanay Thakar, Claudia M Nicolae, George-Lucian Moldovan
PARP14 regulates cyclin D1 expression to promote cell-cycle progression. Oncogene 40 (30) (2021)
Emily M Schleicher, Ashna Dhoonmoon, Lindsey M Jackson, Kristen E Clements, Coryn L Stump, Claudia M Nicolae, George-Lucian Moldovan
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors. PLoS genetics 16 (11) (2020)
Kristen E Clements, Emily M Schleicher, Tanay Thakar, Anastasia Hale, Ashna Dhoonmoon, Nathanial J Tolman, Anchal Sharma, Xinwen Liang, Yuka Imamura Kawasawa, Claudia M Nicolae, Hong-Gang Wang, Subhajyoti De, George-Lucian Moldovan
Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens. Nature communications 11 (1) (2020)
Tanay Thakar, Wendy Leung, Claudia M Nicolae, Kristen E Clements, Binghui Shen, Anja-Katrin Bielinsky, George-Lucian Moldovan
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly. Nature communications 11 (1) (2020)
Tomomi M Yamamoto, Alexandra McMellen, Zachary L Watson, Jennifer Aguilera, Rebecca Ferguson, Elmar Nurmemmedov, Tanay Thakar, George-Lucian Moldovan, Hyunmin Kim, Diana M Cittelly, Annette M Joglar, Elyse P Brennecke, Heidi Wilson, Kian Behbakht, Matthew J Sikora, Benjamin G Bitler
Activation of Wnt signaling promotes olaparib resistant ovarian cancer. Molecular carcinogenesis 58 (10) (2019)
Katherine N Choe, Claudia M Nicolae, Daniel Constantin, Yuka Imamura Kawasawa, Maria Rocio Delgado-Diaz, Subhajyoti De, Raimundo Freire, Veronique Aj Smits, George-Lucian Moldovan
HUWE1 interacts with PCNA to alleviate replication stress. EMBO reports 17 (6) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

George-Lucian Moldovan