George N Pavlakis

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 22

Top Topics

Immune Response

Human Immunodeficiency Virus

Multiple Myeloma

Top Venues

Journal of virology

Journal for immunotherapy of cancer

This page only lists publications with an associated author ORCID identifier.

Publications

Rom S Leidner, Kevin C Conlon, Douglas G McNeel, Andrea Wang-Gillam, Sumati V Gupta, Robert Wesolowski, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Lang Ho Lee, Jessica A O'Keeffe, Nancy Lewis, George N Pavlakis, John A Thompson
First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors. Journal for immunotherapy of cancer 11 (10) (2023)
Santhi Devasundaram, Evangelos Terpos, Margherita Rosati, Ioannis Ntanasis-Stathopoulos, Jenifer Bear, Robert Burns, Stamatia Skourti, Panagiotis Malandrakis, Ioannis P Trougakos, Meletios- Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
XBB.1.5 neutralizing antibodies upon bivalent COVID-19 vaccination are similar to XBB but lower than BQ.1.1. American journal of hematology (2023)
Margherita Rosati, Evangelos Terpos, Jenifer Bear, Robert Burns, Santhi Devasundaram, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Efstathios Kastritis, Meletios- Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom's Macroglobulinemia after BNT162b2 Booster Vaccination. Cancers 14 (23) (2022)
Christina Papanikolaou, Vasiliki Rapti, Dimitris Stellas, Dimitra T Stefanou, Konstantinos Syrigos, George N Pavlakis, Vassilis L Souliotis
Delineating the SARS-CoV-2 Induced Interplay between the Host Immune System and the DNA Damage Response Network. Vaccines 10 (10) (2022)
Kevin C Conlon, Dionysios C Watson, Thomas A Waldmann, Antonio Valentin, Cristina Bergamaschi, Barbara K Felber, Cody J Peer, William Douglas Figg, E Lake Potter, Mario Roederer, Douglas G McNeel, John A Thompson, Sumati V Gupta, Rom S Leidner, Andrea Wang-Gillam, Nehal S Parikh, Debby Long, Sema Kurtulus, Lang Ho Lee, Niladri Roy Chowdhury, Florent Bender, George N Pavlakis
Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors. Journal for immunotherapy of cancer 9 (11) (2022)
Margherita Rosati, Evangelos Terpos, Jenifer Bear, Robert Burns, Santhi Devasundaram, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Efstathios Kastritis, Meletios- Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom's Macroglobulinemia after BNT162b2 Booster Vaccination. Cancers 14 (23) (2022)
Margherita Rosati, Evangelos Terpos, Jenifer Bear, Robert Burns, Santhi Devasundaram, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Efstathios Kastritis, Meletios- Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom's Macroglobulinemia after BNT162b2 Booster Vaccination. Cancers 14 (23) (2022)
Petros Barmpounakis, Nikolaos Demiris, Ioannis Kontoyiannis, George N Pavlakis, Vana Sypsa
Evaluating the effects of second-dose vaccine-delay policies in European countries: A simulation study based on data from Greece. PloS one 17 (4) (2022)
Margherita Rosati, Mahesh Agarwal, Xintao Hu, Santhi Devasundaram, Dimitris Stellas, Bhabadeb Chowdhury, Jenifer Bear, Robert Burns, Duncan Donohue, Laurent Pessaint, Hanne Andersen, Mark G Lewis, Evangelos Terpos, Meletios Athanasios Dimopoulos, Alexander Wlodawer, James I Mullins, David J Venzon, George N Pavlakis, Barbara K Felber
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques. PLoS pathogens 17 (9) (2021)
Cristina Bergamaschi, Hrishikesh Pandit, Bethany A Nagy, Dimitris Stellas, Shawn M Jensen, Jenifer Bear, Maggie Cam, Antonio Valentin, Bernard A Fox, Barbara K Felber, George N Pavlakis
Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10. Journal for immunotherapy of cancer 8 (1) (2021)
Margherita Rosati, Evangelos Terpos, Mahesh Agarwal, Vangelis Karalis, Jenifer Bear, Robert Burns, Xintao Hu, Demetrios Papademetriou, Ioannis Ntanasis-Stathopoulos, Ioannis P Trougakos, Meletios- Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
Distinct neutralization profile of spike variants by antibodies induced upon SARS-CoV-2 infection or vaccination. American journal of hematology (2021)
Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David W Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy. PLoS pathogens 17 (7) (2021)
Thomas P Thomopoulos, Margherita Rosati, Evangelos Terpos, Dimitris Stellas, Xintao Hu, Sevasti Karaliota, Anthi Bouchla, Ioannis Katagas, Anastasia Antoniadou, Andreas Mentis, Sotirios G Papageorgiou, Marianna Politou, Jenifer Bear, Duncan Donohue, Anastasia Kotanidou, Ioannis Kalomenidis, Eleni Korompoki, Robert Burns, Maria Pagoni, Elisavet Grouzi, Stavroula Labropoulou, Kostantinos Stamoulis, Aristotelis Bamias, Sotirios Tsiodras, Meletios- Athanasios Dimopoulos, George N Pavlakis, Vasiliki Pappa, Barbara K Felber
Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma. Viruses 13 (9) (2021)
Evangelos Terpos, Marianna Politou, Theodoros N Sergentanis, Andreas Mentis, Margherita Rosati, Dimitris Stellas, Jenifer Bear, Xintao Hu, Barbara K Felber, Vassiliki Pappa, Maria Pagoni, Elisavet Grouzi, Stavroula Labropoulou, Ioanna Charitaki, Ioannis Ntanasis-Stathopoulos, Dimitra Moschandreou, Anthi Bouhla, Stylianos Saridakis, Eleni Korompoki, Chara Giatra, Tina Bagratuni, Angelos Pefanis, Sotirios Papageorgiou, Alexandros Spyridonidis, Anastasia Antoniadou, Anastasia Kotanidou, Konstantinos Syrigos, Konstantinos Stamoulis, George Panayiotakopoulos, Sotirios Tsiodras, Leonidas Alexopoulos, Meletios- Athanasios Dimopoulos, George N Pavlakis
Anti-SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study. Microorganisms 8 (12) (2020)
Santhi Devasundaram, Margherita Rosati, Antonio Valentin, Svenja Weiss, Vincenza Itri, Hung V Trinh, Jenifer Bear, Bhabadeb Chowdhury, Celia C LaBranche, David Montefiori, Guido Ferrari, Mangala Rao, Xiang-Peng Kong, Susan Zolla-Pazner, George N Pavlakis, Barbara K Felber
Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques. Journal of virology 95 (2) (2020)
Thomas Musich, Vishal Thovarai, David J Venzon, Venkatramanan Mohanram, Iskra Tuero, Leia K Miller-Novak, Sabrina Helmold Hait, Mohammad Arif Rahman, Ruth Hunegnaw, Erin Huiting, Wuxing Yuan, Colm O'hUigin, Tanya Hoang, Yongjun Sui, Celia C LaBranche, David Montefiori, Jenifer Bear, Margherita Rosati, Massimiliano Bissa, Jay A Berzofsky, George N Pavlakis, Barbara K Felber, Genoveffa Franchini, Marjorie Robert-Guroff
A Prime/Boost Vaccine Regimen Alters the Rectal Microbiome and Impacts Immune Responses and Viremia Control Post-Simian Immunodeficiency Virus Infection in Male and Female Rhesus Macaques. Journal of virology 94 (24) (2020)
Sabrina Helmold Hait, Diego A Vargas-Inchaustegui, Thomas Musich, Venkatramanan Mohanram, Iskra Tuero, David J Venzon, Jenifer Bear, Margherita Rosati, Monica Vaccari, Genoveffa Franchini, Barbara K Felber, George N Pavlakis, Marjorie Robert-Guroff
Early T Follicular Helper Cell Responses and Germinal Center Reactions Are Associated with Viremia Control in Immunized Rhesus Macaques. Journal of virology 93 (4) (2019)
Shakti Singh, Eric Gustavo Ramirez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Xintao Hu, Brandon F Keele, Xiaoying X Shen, Georgia D Tomaras, Guido Ferrari, Celia C LaBranche, David C Montefiori, Jishnu Das, Galit Alter, Hung V Trinh, Christopher Hamlin, Mangala Rao, Frances Dayton, Jenifer Bear, Bhabadeb Chowdhury, Candido Alicea, Jeffrey D Lifson, Kate E Broderick, Niranjan Y Sardesai, Sandra J Sivananthan, Christopher B Fox, Steven G Reed, David J Venzon, Vanessa M Hirsch, George N Pavlakis, Barbara K Felber
Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques. Journal of virology 92 (15) (2018)
Paul Munson, Yi Liu, Debra Bratt, James T Fuller, Xintao Hu, George N Pavlakis, Barbara K Felber, James I Mullins, Deborah Heydenburg Fuller
Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection. Human vaccines & immunotherapeutics 14 (7) (2018)
Dionysios C Watson, Bryant C Yung, Cristina Bergamaschi, Bhabadeb Chowdhury, Jenifer Bear, Dimitris Stellas, Aizea Morales-Kastresana, Jennifer C Jones, Barbara K Felber, Xiaoyuan Shawn Chen, George N Pavlakis
Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes. Journal of extracellular vesicles 7 (1) (2018)
Xintao Hu, Zhongyan Lu, Antonio Valentin, Margherita Rosati, Kate E Broderick, Niranjan Y Sardesai, Preston A Marx, James I Mullins, George N Pavlakis, Barbara K Felber
Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques. Human vaccines & immunotherapeutics 14 (9) (2018)
Dionysios C Watson, Eirini Moysi, Antonio Valentin, Cristina Bergamaschi, Santhi Devasundaram, Sotirios P Fortis, Jenifer Bear, Elena Chertova, Julian Bess, Ray Sowder, David J Venzon, Claire Deleage, Jacob D Estes, Jeffrey D Lifson, Constantinos Petrovas, Barbara K Felber, George N Pavlakis
Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes. PLoS pathogens 14 (2) (2018)