Michael K Axthelm (Michael Axthelm)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Topics

Monoclonal Antibody

Antiretroviral Therapy

Hepatitis C Virus

Top Venues

Science advances

Science translational medicine

Journal of immunology (Baltimore, Md. : 1950)

This page only lists publications with an associated author ORCID identifier.

Publications

Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David W Morrow, Mandana Mansouri, Dimple Chakravarty, Teresa Beechwood, Christine Meyer, Luke Uebelhoer, Elvin J Lauron, Andrea N Selseth, Nessy John, Tin Htwe Thin, Siarhei Dzedzik, Colin Havenar-Daughton, Michael K Axthelm, Janet Douglas, Alan J Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G Hansen, Daniel Malouli, Louis J Picker, Klaus Früh
CD8 + T cell targeting of tumor antigens presented by HLA-E. Science advances 10 (19) (2024)
Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David W Morrow, Mandana Mansouri, Dimple Chakravarty, Teresa Beechwood, Christine Meyer, Luke Uebelhoer, Elvin J Lauron, Andrea N Selseth, Nessy John, Tin Htwe Thin, Siarhei Dzedzik, Colin Havenar-Daughton, Michael K Axthelm, Janet Douglas, Alan J Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G Hansen, Daniel Malouli, Louis J Picker, Klaus Früh
CD8 + T cell targeting of tumor antigens presented by HLA-E. Science advances 10 (19) (2024)
Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David W Morrow, Mandana Mansouri, Dimple Chakravarty, Teresa Beechwood, Christine Meyer, Luke Uebelhoer, Elvin J Lauron, Andrea N Selseth, Nessy John, Tin Htwe Thin, Siarhei Dzedzik, Colin Havenar-Daughton, Michael K Axthelm, Janet Douglas, Alan J Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G Hansen, Daniel Malouli, Louis J Picker, Klaus Früh
CD8 + T cell targeting of tumor antigens presented by HLA-E. Science advances 10 (19) (2024)
Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David W Morrow, Mandana Mansouri, Dimple Chakravarty, Teresa Beechwood, Christine Meyer, Luke Uebelhoer, Elvin J Lauron, Andrea N Selseth, Nessy John, Tin Htwe Thin, Siarhei Dzedzik, Colin Havenar-Daughton, Michael K Axthelm, Janet Douglas, Alan J Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G Hansen, Daniel Malouli, Louis J Picker, Klaus Früh
CD8 + T cell targeting of tumor antigens presented by HLA-E. Science advances 10 (19) (2024)
Ravi F Iyer, Marieke C Verweij, Sujit S Nair, David W Morrow, Mandana Mansouri, Dimple Chakravarty, Teresa Beechwood, Christine Meyer, Luke Uebelhoer, Elvin J Lauron, Andrea N Selseth, Nessy John, Tin Htwe Thin, Siarhei Dzedzik, Colin Havenar-Daughton, Michael K Axthelm, Janet Douglas, Alan J Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G Hansen, Daniel Malouli, Louis J Picker, Klaus Früh
CD8 + T cell targeting of tumor antigens presented by HLA-E. Science advances 10 (19) (2024)
Michael J Ricciardi, Lauren N Rust, Nuria Pedreño-Lopez, Sofiya Yusova, Sreya Biswas, Gabriela M Webb, Lucas Gonzalez-Nieto, Thomas B Voigt, Johan J Louw, Fernanda D Laurino, John R DiBello, Hans-Peter Raué, Aaron M Barber-Axthelm, Kimberly Chun, Samantha Uttke, Lidiane M S Raphael, Aaron Yrizarry-Medina, Brandon C Rosen, Rebecca Agnor, Lina Gao, Caralyn S Labriola, Michael K Axthelm, Jeremy V Smedley, Justin G Julander, Myrna Cristina Bonaldo, Laura M Walker, Ilhem Messaoudi, Mark K Slifka, Dennis R Burton, Esper Georges Kallás, Jonah B Sacha, David I Watkins, Benjamin J Burwitz
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection. Science translational medicine 15 (689) (2023)
Michael J Ricciardi, Lauren N Rust, Nuria Pedreño-Lopez, Sofiya Yusova, Sreya Biswas, Gabriela M Webb, Lucas Gonzalez-Nieto, Thomas B Voigt, Johan J Louw, Fernanda D Laurino, John R DiBello, Hans-Peter Raué, Aaron M Barber-Axthelm, Kimberly Chun, Samantha Uttke, Lidiane M S Raphael, Aaron Yrizarry-Medina, Brandon C Rosen, Rebecca Agnor, Lina Gao, Caralyn S Labriola, Michael K Axthelm, Jeremy V Smedley, Justin G Julander, Myrna Cristina Bonaldo, Laura M Walker, Ilhem Messaoudi, Mark K Slifka, Dennis R Burton, Esper Georges Kallás, Jonah B Sacha, David I Watkins, Benjamin J Burwitz
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection. Science translational medicine 15 (689) (2023)
Daniel Malouli, Scott G Hansen, Meaghan H Hancock, Colette M Hughes, Julia C Ford, Roxanne M Gilbride, Abigail B Ventura, David W Morrow, Kurt T Randall, Husam Taher, Luke S Uebelhoer, Matthew R McArdle, Courtney R Papen, Renee Espinosa Trethewy, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Justin M Greene, Michael K Axthelm, Danica Shao, Paul T Edlefsen, Finn Grey, Jay A Nelson, Jeffrey D Lifson, Daniel Streblow, Jonah B Sacha, Klaus Früh, Louis J Picker
Cytomegaloviral determinants of CD8+ T cell programming and RhCMV/SIV vaccine efficacy. Science immunology 6 (57) (2022)
Scott G Hansen, Meaghan H Hancock, Daniel Malouli, Emily E Marshall, Colette M Hughes, Kurt T Randall, David W Morrow, Julia C Ford, Roxanne M Gilbride, Andrea N Selseth, Renee Espinosa Trethewy, Lindsey M Bishop, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Lorna Silipino, Michael Nekorchuk, Kathleen Busman-Sahay, Jacob D Estes, Michael K Axthelm, Jeremy V Smedley, Danica Shao, Paul T Edlefsen, Jeffrey D Lifson, Klaus Früh, Jay A Nelson, Louis J Picker
Myeloid cell tropism enables MHC-E-restricted CD8 + T cell priming and vaccine efficacy by the RhCMV/SIV vaccine. Science immunology 7 (72) (2022)
Afam A Okoye, Remi Fromentin, Hiroshi Takata, Jessica H Brehm, Yoshinori Fukazawa, Bryan Randall, Marion Pardons, Vincent Tai, Jun Tang, Jeremy V Smedley, Michael K Axthelm, Jeffrey D Lifson, Louis J Picker, David Favre, Lydie Trautmann, Nicolas Chomont
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription. PLoS pathogens 18 (1) (2022)
Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Christine M Fennessey, Miranda B Fischer, Oriene Shiel, Tonya Swanson, Christine M Shriver-Munsch, Hugh B Crank, Kimberly M Armantrout, Aaron M Barber-Axthelm, Charlotte A Langner, Cassandra R Moats, Caralyn S Labriola, Rhonda P MacAllister, Michael K Axthelm, Jason M Brenchley, Brandon F Keele, Jacob D Estes, Scott G Hansen, Jeremy V Smedley
Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. PLoS pathogens 17 (5) (2021)
Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David W Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy. PLoS pathogens 17 (7) (2021)
Marieke C Verweij, Scott G Hansen, Ravi F Iyer, Nessy John, Daniel Malouli, David W Morrow, Isabel Scholz, Jennie L Womack, Shaheed Abdulhaqq, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Julia C Ford, Andrea N Selseth, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Danica Shao, Jonah B Sacha, Michael K Axthelm, Paul T Edlefsen, Jeffrey D Lifson, Louis J Picker, Klaus Früh
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy. Science (New York, N.Y.) 372 (6541) (2021)
Husam Taher, Eisa Mahyari, Craig Kreklywich, Luke S Uebelhoer, Matthew R McArdle, Matilda J Moström, Amruta Bhusari, Michael Nekorchuk, Xiaofei E, Travis Whitmer, Elizabeth A Scheef, Lesli M Sprehe, Dawn L Roberts, Colette M Hughes, Kerianne A Jackson, Andrea N Selseth, Abigail B Ventura, Hillary C Cleveland-Rubeor, Yujuan Yue, Kimberli A Schmidt, Danica Shao, Paul T Edlefsen, Jeremy V Smedley, Timothy F Kowalik, Richard James Stanton, Michael K Axthelm, Jacob D Estes, Scott G Hansen, Amitinder Kaur, Peter A Barry, Benjamin N Bimber, Louis J Picker, Daniel N Streblow, Klaus Früh, Daniel Malouli
In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome. PLoS pathogens 16 (11) (2020)
Gabriela M Webb, Jhomary Molden, Kathleen Busman-Sahay, Shaheed Abdulhaqq, Helen L Wu, Whitney C Weber, Katherine B Bateman, Jason S Reed, Mina Northrup, Nicholas Maier, Shiho Tanaka, Lina Gao, Brianna C Davey, Benjamin L Carpenter, Michael K Axthelm, Jeffrey J Stanton, Jeremy V Smedley, Justin M Greene, Jeffrey T Safrit, Jacob D Estes, Pamela J Skinner, Jonah B Sacha
The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques. PLoS pathogens 16 (3) (2020)
Scott G Hansen, Emily E Marshall, Daniel Malouli, Abigail B Ventura, Colette M Hughes, Emily Ainslie, Julia C Ford, David W Morrow, Roxanne M Gilbride, Jin Y Bae, Alfred W Legasse, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J Bosche, Michael Hull, Jennie L Womack, Jason Shao, Paul T Edlefsen, Jason S Reed, Benjamin J Burwitz, Jonah B Sacha, Michael K Axthelm, Klaus Früh, Jeffrey D Lifson, Louis J Picker
A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge. Science translational medicine 11 (501) (2020)
Mariya B Shapiro, Tracy Cheever, Delphine C Malherbe, Shilpi Pandey, Jason Reed, Eun Sung Yang, Keyun Wang, Amarendra Pegu, Xuejun Chen, Don Siess, David Burke, Heidi Henderson, Rebecca Lewinsohn, Miranda Fischer, Jeffrey J Stanton, Michael K Axthelm, Christoph Kahl, Byung Park, Anne D Lewis, Jonah B Sacha, John R Mascola, Ann J Hessell, Nancy L Haigwood
Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity. Nature communications 11 (1) (2020)
Benjamin J Burwitz, Patrick K Hashiguchi, Mandana Mansouri, Christine Meyer, Roxanne M Gilbride, Sreya Biswas, Jennie L Womack, Jason S Reed, Helen L Wu, Michael K Axthelm, Scott G Hansen, Louis J Picker, Klaus Früh, Jonah B Sacha
MHC-E-Restricted CD8+ T Cells Target Hepatitis B Virus-Infected Human Hepatocytes. Journal of immunology (Baltimore, Md. : 1950) 204 (8) (2020)
Emily E Marshall, Daniel Malouli, Scott G Hansen, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Emily Ainslie, Andrea N Selseth, Julia C Ford, David Burke, Craig N Kreklywich, Jennie L Womack, Alfred W Legasse, Michael K Axthelm, Christoph A Kahl, Daniel Streblow, Paul T Edlefsen, Louis J Picker, Klaus Früh
Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity. Science translational medicine 11 (501) (2020)
Afam A Okoye, Maren Q DeGottardi, Yoshinori Fukazawa, Mukta Vaidya, Chike O Abana, Audrie L Konfe, Devin N Fachko, Derick M Duell, He Li, Richard Lum, Lina Gao, Byung S Park, Rebecca L Skalsky, Anne D Lewis, Michael K Axthelm, Jeffrey D Lifson, Scott W Wong, Louis J Picker
Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques. Journal of immunology (Baltimore, Md. : 1950) 203 (11) (2019)
Scott G Hansen, Daniel E Zak, Guangwu Xu, Julia C Ford, Emily E Marshall, Daniel Malouli, Roxanne M Gilbride, Colette M Hughes, Abigail B Ventura, Emily Ainslie, Kurt T Randall, Andrea N Selseth, Parker Rundstrom, Lauren Herlache, Matthew S Lewis, Haesun Park, Shannon L Planer, John M Turner, Miranda Fischer, Christina Armstrong, Robert C Zweig, Joseph Valvo, Jackie M Braun, Smitha Shankar, Lenette Lu, Andrew W Sylwester, Alfred W Legasse, Martin Messerle, Michael A Jarvis, Lynn M Amon, Alan Aderem, Galit Alter, Dominick J Laddy, Michele Stone, Aurelio Bonavia, Thomas G Evans, Michael K Axthelm, Klaus Früh, Paul T Edlefsen, Louis J Picker
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine. Nature medicine 24 (2) (2018)
Alec J Hirsch, Victoria H J Roberts, Peta L Grigsby, Nicole Haese, Matthias C Schabel, Xiaojie Wang, Jamie O Lo, Zheng Liu, Christopher D Kroenke, Jessica L Smith, Meredith Kelleher, Rebecca Broeckel, Craig N Kreklywich, Christopher J Parkins, Michael Denton, Patricia Smith, Victor DeFilippis, William Messer, Jay A Nelson, Jon D Hennebold, Marjorie Grafe, Lois Colgin, Anne Lewis, Rebecca Ducore, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Rhonda MacAllister, Ashlee V Moses, Terry K Morgan, Antonio E Frias, Daniel N Streblow
Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology. Nature communications 9 (1) (2018)
Afam A Okoye, Scott G Hansen, Mukta Vaidya, Yoshinori Fukazawa, Haesun Park, Derick M Duell, Richard Lum, Colette M Hughes, Abigail B Ventura, Emily Ainslie, Julia C Ford, David W Morrow, Roxanne M Gilbride, Alfred W Legasse, Joseph Hesselgesser, Romas Geleziunas, Yuan Li, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Bhavesh R Borate, Paul T Edlefsen, Michael K Axthelm, Louis J Picker, Jeffrey D Lifson
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound. Nature medicine 24 (9) (2018)
Helen L Wu, Roger W Wiseman, Colette M Hughes, Gabriela M Webb, Shaheed A Abdulhaqq, Benjamin N Bimber, Katherine B Hammond, Jason S Reed, Lina Gao, Benjamin J Burwitz, Justin M Greene, Fidel Ferrer, Alfred W Legasse, Michael K Axthelm, Byung S Park, Simon Brackenridge, Nicholas J Maness, Andrew J McMichael, Louis J Picker, David H O'Connor, Scott G Hansen, Jonah B Sacha
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques. Journal of immunology (Baltimore, Md. : 1950) 200 (1) (2017)
Maren Q DeGottardi, Afam A Okoye, Mukta Vaidya, Aarthi Talla, Audrie L Konfe, Matthew D Reyes, Joseph A Clock, Derick M Duell, Alfred W Legasse, Amit Sabnis, Byung S Park, Michael K Axthelm, Jacob D Estes, Keith A Reiman, Rafick-Pierre Sekaly, Louis J Picker
Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. Journal of immunology (Baltimore, Md. : 1950) 197 (4) (2016)