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Gerhard Grüber

ORCID

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 22

Top Venues

Antimicrobial agents and chemotherapy

FEBS letters

ACS infectious diseases

The FEBS journal

Nanyang Technological University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Nanyang Technological University

Singapore

Professor :: School of Biological Sciences

Publications

Syed Moiz Ahmed, Priya Ragunathan, Joon Shin, Sabrina Peter, Sabrina Kleissle, Martin Neuenschwander, Reinhold Schäfer, Jens Peter V Kries, Gerhard Grüber, Peter Dröge
The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions. FEBS letters (2023)
Priya Ragunathan, Pearly Shuyi Ng, Samsher Singh, Wee Han Poh, Dennis Litty, Nitin Pal Kalia, Simon Larsson, Amaravadhi Harikishore, Scott A Rice, Philip W Ingham, Volker Müller, Garrett C Moraski, Marvin J Miller, Thomas Dick, Kevin Pethe, Gerhard Grüber
GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876. Microbiology spectrum (2023)
Amaravadhi Harikishore, Vikneswaran Mathiyazakan, Kevin Pethe, Gerhard Grüber
Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery. Expert opinion on drug discovery (2023)
Vikneswaran Mathiyazakan, Chui-Fann Wong, Amaravadhi Harikishore, Kevin Pethe, Gerhard Grüber
Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I. Antimicrobial agents and chemotherapy (2023)
Wuan-Geok Saw, Khoa Cong Minh Le, Joon Shin, Jes Hui Min Kwek, Chui Fann Wong, Priya Ragunathan, Tuck Choy Fong, Volker Müller, Gerhard Grüber
Atomic insights of an up and down conformation of the Acinetobacter baumannii F 1 -ATPase subunit ε and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (7) (2023)
Wuan-Geok Saw, Chen Yen Leow, Amaravadhi Harikishore, Joon Shin, Malcolm S Cole, Wassihun Wedajo Aragaw, Priya Ragunathan, Pooja Hegde, Courtney C Aldrich, Thomas Dick, Gerhard Grüber
Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor. ACS infectious diseases 8 (7) (2022)
Priya Ragunathan, Thomas Dick, Gerhard Grüber
Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1. Antimicrobial agents and chemotherapy 66 (5) (2022)
Amaravadhi Harikishore, Wuan-Geok Saw, Priya Ragunathan, Dennis Litty, Thomas Dick, Volker Müller, Gerhard Grüber
Mutational Analysis of Mycobacterial F-ATP Synthase Subunit δ Leads to a Potent δ Enzyme Inhibitor. ACS chemical biology 17 (3) (2022)
Chui Fann Wong, Wuan-Geok Saw, Sandip Basak, Mio Sano, Hiroshi Ueno, Hwee Wen Kerk, Dennis Litty, Priya Ragunathan, Thomas Dick, Volker Müller, Hiroyuki Noji, Gerhard Grüber
Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrobial agents and chemotherapy (2022)
Joon Shin, Amaravadhi Harikishore, Chui Fann Wong, Priya Ragunathan, Thomas Dick, Gerhard Grüber
Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor. The FEBS journal 289 (20) (2022)
Amaravadhi Harikishore, Chui-Fann Wong, Priya Ragunathan, Dennis Litty, Volker Müller, Gerhard Grüber
Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ. Antibiotics (Basel, Switzerland) 10 (12) (2021)
Joon Shin, Bharti Singal, Ardina Grüber, David Meng Kit Wong, Priya Ragunathan, Gerhard Grüber
Atomic structure of the regulatory TGS domain of Rel protein from Mycobacterium tuberculosis and its interaction with deacylated tRNA. FEBS letters (2021)
Priya Ragunathan, Malcolm Cole, Chitra Latka, Wassihun Wedajo Aragaw, Pooja Hegde, Joon Shin, Malathy Sony Subramanian Manimekalai, Sankaranarayanan Rishikesan, Courtney C Aldrich, Thomas Dick, Gerhard Grüber
Mycobacterium tuberculosis PanD Structure-Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor. ACS chemical biology 16 (6) (2021)
Zhu Qiao, Edwin R Lampugnani, Xin-Fu Yan, Ghazanfar Abbas Khan, Wuan Geok Saw, Patrick Hannah, Feng Qian, Jacob Calabria, Yansong Miao, Gerhard Grüber, Staffan Persson, Yong-Gui Gao
Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Shi Min Sherilyn Chong, Malathy Sony Subramanian Manimekalai, Jickky Palmae Sarathy, Zoe C Williams, Liam K Harold, Gregory M Cook, Thomas Dick, Kevin Pethe, Roderick W Bates, Gerhard Grüber
Antituberculosis Activity of the Antimalaria Cytochrome bcc Oxidase Inhibitor SCR0911. ACS infectious diseases 6 (4) (2020)
Adam Hotra, Priya Ragunathan, Pearly Shuyi Ng, Pattarakiat Seankongsuk, Amaravadhi Harikishore, Jickky Palmae Sarathy, Wuan-Geok Saw, Umayal Lakshmanan, Patcharaporn Sae-Lao, Nitin Pal Kalia, Joon Shin, Revathy Kalyanasundaram, Sivaraj Anbarasu, Krupakar Parthasarathy, Chaudhari Namrata Pradeep, Harshyaa Makhija, Peter Dröge, Anders Poulsen, Jocelyn Hui Ling Tan, Kevin Pethe, Thomas Dick, Roderick W Bates, Gerhard Grüber
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines. Angewandte Chemie (International ed. in English) 59 (32) (2020)
Ekaterina Sviriaeva, Malathy Sony Subramanian Manimekalai, Gerhard Grüber, Kevin Pethe
Features and Functional Importance of Key Residues of the Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS infectious diseases 6 (7) (2020)
Joon Shin, Bharti Singal, Malathy Sony Subramanian Manimekalai, Ming Wei Chen, Priya Ragunathan, Gerhard Grüber
Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein. The FEBS journal 288 (7) (2020)
Amaravadhi Harikishore, Sherilyn Shi Min Chong, Priya Ragunathan, Roderick W Bates, Gerhard Grüber
Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase. Molecular diversity 25 (1) (2020)
Chui-Fann Wong, Gerhard Grüber
The Unique C-Terminal Extension of Mycobacterial F-ATP Synthase Subunit α Is the Major Contributor to Its Latent ATP Hydrolysis Activity. Antimicrobial agents and chemotherapy 64 (12) (2020)
Chui-Fann Wong, Aik-Meng Lau, Amaravadhi Harikishore, Wuan-Geok Saw, Joon Shin, Priya Ragunathan, Shashi Bhushan, So-Fong Cam Ngan, Siu Kwan Sze, Roderick W Bates, Thomas Dick, Gerhard Grüber
A systematic assessment of mycobacterial F1 -ATPase subunit ε's role in latent ATPase hydrolysis. The FEBS journal 288 (3) (2020)
Shi Min Sherilyn Chong, Neelagandan Kamariah, Gerhard Grüber
Residues of helix ɑ2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C. FEBS letters 594 (17) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Gerhard Grüber