Expert opinion on drug discovery

Keyphrases

Publications

volume 19, number 5, 2024

Izabela Lepiarz-Raba, Taufik Hidayat, Anthony J Hannan, Ali Jawaid
Potential Alzheimer's disease drug targets identified through microglial biology research. Expert opinion on drug discovery 19 (5) (2024)
Michael Murray
Omega-3 polyunsaturated fatty acid derived lipid mediators: a comprehensive update on their application in anti-cancer drug discovery. Expert opinion on drug discovery 19 (5) (2024)
Ioannis Avgerinos, Panagiota Kakotrichi, Thomas Karagiannis, Eleni Bekiari, Apostolos Tsapas
The preclinical discovery and clinical evaluation of tirzepatide for the treatment of type 2 diabetes. Expert opinion on drug discovery 19 (5) (2024)
Julija Valančienė, Kazimieras Melaika, Aleksandra Šliachtenko, Kamilė Šiaurytė-Jurgelėnė, Aleksandra Ekkert, Dalius Jatuzis
Stroke genetics and how it Informs novel drug discovery. Expert opinion on drug discovery 19 (5) (2024)
Ivette A Nuñez, Anya Crane, Ian Crozier, Gabriella Worwa, J Thomas Beatty
Treatment of highly virulent mammarenavirus infections-status quo and future directions. Expert opinion on drug discovery 19 (5) (2024)
Stefano Romussi, Sebastián Giunti, Natalia Andersen, María José De Rosa
C. elegans : a prominent platform for modeling and drug screening in neurological disorders. Expert opinion on drug discovery 19 (5) (2024)
Izabela Lepiarz-Raba, Taufik Hidayat, Anthony J Hannan, Ali Jawaid
Potential Alzheimer's disease drug targets identified through microglial biology research. Expert opinion on drug discovery 19 (5) (2024)
José L Medina-Franco, Edgar López-López
What is the plausibility that all drugs will be designed by computers by the end of the decade? Expert opinion on drug discovery 19 (5) (2024)
Michael Murray
Omega-3 polyunsaturated fatty acid derived lipid mediators: a comprehensive update on their application in anti-cancer drug discovery. Expert opinion on drug discovery 19 (5) (2024)
Ivette A Nuñez, Anya Crane, Ian Crozier, Gabriella Worwa, J Thomas Beatty
Treatment of highly virulent mammarenavirus infections-status quo and future directions. Expert opinion on drug discovery 19 (5) (2024)
Julija Valančienė, Kazimieras Melaika, Aleksandra Šliachtenko, Kamilė Šiaurytė-Jurgelėnė, Aleksandra Ekkert, Dalius Jatuzis
Stroke genetics and how it Informs novel drug discovery. Expert opinion on drug discovery 19 (5) (2024)
Michael Murray
Omega-3 polyunsaturated fatty acid derived lipid mediators: a comprehensive update on their application in anti-cancer drug discovery. Expert opinion on drug discovery 19 (5) (2024)

volume 19, number 6, 2024

Victor A Adediwura, Kushal Koirala, Hung Nguyen Do, Jinan Wang, Yinglong Miao
Understanding the impact of binding free energy and kinetics calculations in modern drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Madia Lozupone, Vittorio Dibello, Rodolfo Sardone, Fabio Castellana, Roberta Zupo, Luisa Lampignano, Ilaria Bortone, Roberta Stallone, Mario Altamura, Antonello Bellomo, Antonio Daniele, Vincenzo Solfrizzi, Francesco Panza
Lessons learned from the failure of solanezumab as a prospective treatment strategy for Alzheimer's disease. Expert opinion on drug discovery 19 (6) (2024)
Zhou Dongrui, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Innovative peptide architectures: advancements in foldamers and stapled peptides for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Visvaldas Kairys, Lina Baranauskienė, Migle Kazlauskiene, Asta Zubrienė, Vytautas Petrauskas, Daumantas Matulis, Egidijus Kazlauskas
Recent advances in computational and experimental protein-ligand affinity determination techniques. Expert opinion on drug discovery 19 (6) (2024)
Ramakrishna Nirogi, Pradeep Jayarajan, Vijay Benade, Renny Abraham, Vinod Kumar Goyal
Hits and misses with animal models of narcolepsy and the implications for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana, Thibault Joseph William Jacques Dit Lapierre, André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha, Daniel Barbosa Liarte, Mariana Laureano de Souza, Gustavo Henrique Goulart Trossini, Celso de Oliveira Rezende Júnior, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi , the causative agent of Chagas disease. Expert opinion on drug discovery 19 (6) (2024)
Guixian Zhao, Mengping Zhu, Yangfeng Li, Gong Zhang, Yizhou Li
Using DNA-encoded libraries of fragments for hit discovery of challenging therapeutic targets. Expert opinion on drug discovery 19 (6) (2024)
Davide Bassani, Neil John Parrott, Nenad Manevski, Jitao David Zhang
Another string to your bow: machine learning prediction of the pharmacokinetic properties of small molecules. Expert opinion on drug discovery 19 (6) (2024)
Victor A Adediwura, Kushal Koirala, Hung Nguyen Do, Jinan Wang, Yinglong Miao
Understanding the impact of binding free energy and kinetics calculations in modern drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Victor A Adediwura, Kushal Koirala, Hung Nguyen Do, Jinan Wang, Yinglong Miao
Understanding the impact of binding free energy and kinetics calculations in modern drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Zhou Dongrui, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Innovative peptide architectures: advancements in foldamers and stapled peptides for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana, Thibault Joseph William Jacques Dit Lapierre, André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha, Daniel Barbosa Liarte, Mariana Laureano de Souza, Gustavo Henrique Goulart Trossini, Celso de Oliveira Rezende Júnior, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi , the causative agent of Chagas disease. Expert opinion on drug discovery 19 (6) (2024)
Guixian Zhao, Mengping Zhu, Yangfeng Li, Gong Zhang, Yizhou Li
Using DNA-encoded libraries of fragments for hit discovery of challenging therapeutic targets. Expert opinion on drug discovery 19 (6) (2024)
Ramakrishna Nirogi, Pradeep Jayarajan, Vijay Benade, Renny Abraham, Vinod Kumar Goyal
Hits and misses with animal models of narcolepsy and the implications for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Visvaldas Kairys, Lina Baranauskienė, Migle Kazlauskiene, Asta Zubrienė, Vytautas Petrauskas, Daumantas Matulis, Egidijus Kazlauskas
Recent advances in computational and experimental protein-ligand affinity determination techniques. Expert opinion on drug discovery 19 (6) (2024)
Davide Bassani, Neil John Parrott, Nenad Manevski, Jitao David Zhang
Another string to your bow: machine learning prediction of the pharmacokinetic properties of small molecules. Expert opinion on drug discovery 19 (6) (2024)
Ana Margarida Sousa, Maria Olívia Pereira
Challenges with drug efficacy prediction of in vitro models of biofilms infecting cystic fibrosis airway. Expert opinion on drug discovery 19 (6) (2024)
Claudio N Cavasotto, Juan I Di Filippo, Valeria Scardino
Lessons learnt from machine learning in early stages of drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Madia Lozupone, Vittorio Dibello, Rodolfo Sardone, Fabio Castellana, Roberta Zupo, Luisa Lampignano, Ilaria Bortone, Roberta Stallone, Mario Altamura, Antonello Bellomo, Antonio Daniele, Vincenzo Solfrizzi, Francesco Panza
Lessons learned from the failure of solanezumab as a prospective treatment strategy for Alzheimer's disease. Expert opinion on drug discovery 19 (6) (2024)

volume 19, number 7, 2024

Cecília R C Calado
Bridging the gap between target-based and phenotypic-based drug discovery. Expert opinion on drug discovery 19 (7) (2024)
Carlo Baraldi, Dagmar Beier, Paolo Martelletti, Lanfranco Pellesi
The preclinical discovery and development of atogepant for migraine prophylaxis. Expert opinion on drug discovery 19 (7) (2024)
Chang Liu, Hui Zhang
Data processing for high-throughput mass spectrometry in drug discovery. Expert opinion on drug discovery 19 (7) (2024)
Valentina Vitali, Lara Massai, Luigi Messori
Strategies for the design of analogs of auranofin endowed with anticancer potential. Expert opinion on drug discovery 19 (7) (2024)
Ayan Mukherjee, Vilas D Kadam, Qi Miao, Wanheng Zhang, Kevin R MacKenzie, Zhi Tan, Mingxing Teng
On-demand modular assembly for expedited PROTAC development. Expert opinion on drug discovery 19 (7) (2024)
Diogo Teles, Barry M Fine
Using induced pluripotent stem cells for drug discovery in arrhythmias. Expert opinion on drug discovery 19 (7) (2024)
Weijie Zhang, R Stephanie Huang
Computer-aided drug discovery strategies for novel therapeutics for prostate cancer leveraging next-generating sequencing data. Expert opinion on drug discovery 19 (7) (2024)
Yang Zhou, Fan Zhou, Shujing Xu, Dazhou Shi, Dang Ding, Shuo Wang, Vasanthanathan Poongavanam, Kai Tang, Xinyong Liu, Peng Zhan
Hydrophobic tagging of small molecules: an overview of the literature and future outlook. Expert opinion on drug discovery 19 (7) (2024)
Diogo Teles, Barry M Fine
Using induced pluripotent stem cells for drug discovery in arrhythmias. Expert opinion on drug discovery 19 (7) (2024)
Donatos Tsamoulis, Loukianos S Rallidis, Constantine E Kosmas
Inclisiran: the preclinical discovery and development of a novel therapy for the treatment of atherosclerosis. Expert opinion on drug discovery 19 (7) (2024)

volume 19, number 8, 2024

Catherine J Hutchings, Aaron K Sato
Phage display technology and its impact in the discovery of novel protein-based drugs. Expert opinion on drug discovery 19 (8) (2024)
Lihui Duo, Yu Liu, Jianfeng Ren, Bencan Tang, Jonathan D Hirst
Artificial intelligence for small molecule anticancer drug discovery. Expert opinion on drug discovery 19 (8) (2024)
Sahar F Bannoura, Husain Yar Khan, Md Hafiz Uddin, Ramzi M Mohammad, Boris C Pasche, Asfar S Azmi
Targeting guanine nucleotide exchange factors for novel cancer drug discovery. Expert opinion on drug discovery 19 (8) (2024)
Yongji Zeng, A Craig Lockhart, Ramon U Jin
The preclinical discovery and development of zolbetuximab for the treatment of gastric cancer. Expert opinion on drug discovery 19 (8) (2024)
Rebecca A Gallego, Martin P Edwards, T Patrick Montgomery
An update on lipophilic efficiency as an important metric in drug design. Expert opinion on drug discovery 19 (8) (2024)
Vijay H Masand, Sami Al-Hussain, Abdullah Y Alzahrani, Aamal A Al-Mutairi, Arwa Sultan Alqahtani, Abdul Samad, Ahmed M Alafeefy, Rahul D Jawarkar, Magdi E A Zaki
Unveiling dynamics of nitrogen content and selected nitrogen heterocycles in thrombin inhibitors: a ceteris paribus approach. Expert opinion on drug discovery 19 (8) (2024)
Sophia You, Glen McIntyre, Toby Passioura
The coming of age of cyclic peptide drugs: an update on discovery technologies. Expert opinion on drug discovery 19 (8) (2024)
Laszlo Otvos
The latest trends in peptide drug discovery and future challenges. Expert opinion on drug discovery 19 (8) (2024)
Alan Talevi, Carolina Bellera
An update on the novel methods for the discovery of antiseizure and antiepileptogenic medications: where are we in 2024? Expert opinion on drug discovery 19 (8) (2024)