Graham R Moran (Graham Moran)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 29

Top Topics

Molecular Dynamics Simulations

Reactive Oxygen Species

Top Venues

ACS chemical biology

Journal of the American Chemical Society

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Corine O Smith, Graham R Moran
Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from Lactoccocus lactis : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis. Biochemistry (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Correction to "Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase". ACS chemical biology 19 (8) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology (2024)
Corine O Smith, Graham R Moran
Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from Lactoccocus lactis : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis. Biochemistry 63 (10) (2024)
Corine O Smith, Graham R Moran
Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from Lactoccocus lactis : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis. Biochemistry 63 (10) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Correction to "Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase". ACS chemical biology (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Allison N Devitt, Abigail L Vargas, Wei Zhu, Benjamin James Des Soye, Fatma Ayaloglu Butun, Tyler Alt, Nicholas Kaley, Glaucio Monteiro Ferreira, Graham R Moran, Michael P Snyder, Dali Liu, Richard B Silverman
Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. ACS chemical biology 19 (5) (2024)
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham R Moran, Prakasha Kempaiah, Narayan S Hosmane, Minoru Suzuki, Daniel P Becker
Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry. International journal of molecular sciences 24 (8) (2023)
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham R Moran, Prakasha Kempaiah, Narayan S Hosmane, Minoru Suzuki, Daniel P Becker
Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry. International journal of molecular sciences 24 (8) (2023)
Wei Zhu, Arseniy Butrin, Rafael D Melani, Peter Francis Doubleday, Glaucio Monteiro Ferreira, Maurício Temotheo Tavares, Thahani S Habeeb Mohammad, Brett A Beaupre, Michael P Snyder, Graham R Moran, Dali Liu, Richard B Silverman
Correction to "Rational Design, Synthesis, and Mechanism of (3 S ,4 R )-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase". Journal of the American Chemical Society (2023)
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham R Moran, Prakasha Kempaiah, Narayan S Hosmane, Minoru Suzuki, Daniel P Becker
Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry. International journal of molecular sciences 24 (8) (2023)
Madison M Smith, Tyler B Alt, David L Williams, Graham R Moran
Descriptive Analysis of Transient-State Observations for Thioredoxin/Glutathione Reductase (Sec597Cys) from Schistosoma mansoni . Biochemistry (2023)
Nikola Kenjić, Kathleen M Meneely, Daniel J Wherritt, Melissa C Denler, Timothy A Jackson, Graham R Moran, Audrey L Lamb
Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis. Journal of the American Chemical Society 144 (28) (2022)
Wei Zhu, Arseniy Butrin, Rafael Donadélli Melani, Peter Francis Doubleday, Glaucio Monteiro Ferreira, Maurício Temotheo Tavares, Thahani S Habeeb Mohammad, Brett A Beaupre, Michael P Snyder, Graham R Moran, Dali Liu, Richard B Silverman
Rational Design, Synthesis, and Mechanism of (3 S ,4 R )-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. Journal of the American Chemical Society 144 (12) (2022)
Dariush C Forouzesh, Brett A Beaupre, Arseniy Butrin, Zdzislaw Wawrzak, Dali Liu, Graham R Moran
The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil. Biochemistry 60 (14) (2021)
Sida Shen, Arseniy Butrin, Peter F Doubleday, Rafael D Melani, Brett A Beaupre, Mauricio T Tavares, Glaucio Monteiro Ferreira, Michael P Snyder, Graham R Moran, Dali Liu, Richard B Silverman
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. Journal of the American Chemical Society 143 (23) (2021)
Brett A Beaupre, Dariush C Forouzesh, Arseniy Butrin, Dali Liu, Graham R Moran
Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry 60 (22) (2021)
Madison M Smith, Brett A Beaupre, Dariush C Fourozesh, Kathleen M Meneely, Audrey L Lamb, Graham R Moran
Finding Ways to Relax: A Revisionistic Analysis of the Chemistry of E. coli GTP Cyclohydrolase II. Biochemistry 60 (40) (2021)
Joseph V Roman, Trevor R Melkonian, Nicholas R Silvaggi, Graham R Moran
Correction to "Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States". Biochemistry 59 (35) (2020)
Audrey G O'Neill, Brett A Beaupre, Yuanzhang Zheng, Dali Liu, Graham R Moran
NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? Applied and environmental microbiology 86 (22) (2020)
Arseniy Butrin, Brett A Beaupre, Noel Kadamandla, Peidong Zhao, Sida Shen, Richard B Silverman, Graham R Moran, Dali Liu
Structural and Kinetic Analyses Reveal the Dual Inhibition Modes of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic Acid (BCF3). ACS chemical biology 16 (1) (2020)
Brett A Beaupre, Dariush C Forouzesh, Graham R Moran
Transient-State Analysis of Porcine Dihydropyrimidine Dehydrogenase Reveals Reductive Activation by NADPH. Biochemistry 59 (26) (2020)
Joseph V Roman, Trevor R Melkonian, Nicholas R Silvaggi, Graham R Moran
Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States. Biochemistry 58 (52) (2019)