Gregory Caleb Howard (Gregory C Howard)

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 18

Top Topics

Acute Myeloid Leukemia

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition. eLife 12 (2024)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kevin B Teuscher, Somenath Chowdhury, Kenneth M Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M South, John L Sensintaffar, Tyson A Rietz, Soumita Goswami, Jing Wang, Brian C Grieb, Shelly L Lorey, Gregory Caleb Howard, Qi Liu, William J Moore, Gordon M Stott, William P Tansey, Taekyu Lee, Stephen W Fesik
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)