Alexander James Silver (Alexander J Silver)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 32

Top Venues

Blood cancer journal

Cancer research

Blood advances

Proceedings of the National Academy of Sciences of the United States of America

Brigham and Women's Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Brigham and Women's Hospital

United States

Research Assistant :: Hematology

Publications

Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (11) (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Alexander James Silver, Donovan J Brown, Sarah D Olmstead, Jackson M Watke, Agnieszka E Gorska, Londa Tanner, Haley E Ramsey, Michael R Savona
Repair of leukemia-associated single nucleotide variants via interallelic gene conversion. bioRxiv : the preprint server for biology (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia. Cancer research (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Christian T Meyer, Brianna N Smith, Jing Wang, Kevin B Teuscher, Brian C Grieb, Gregory Caleb Howard, Alexander James Silver, Shelly L Lorey, Gordon M Stott, William J Moore, Taekyu Lee, Michael R Savona, April M Weissmiller, Qi Liu, Vito Quaranta, Stephen W Fesik, William P Tansey
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (11) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Ashwin Kishtagari, M A Wasay Khan, Yajing Li, Caitlyn Vlasschaert, Naimisha Marneni, Alexander James Silver, Kelly von Beck, Travis Spaulding, Shannon Stockton, Christina Snider, Andrew Sochacki, Dixon Dorand, Taralynn M Mack, P Brent Ferrell, Yaomin Xu, Cosmin A Bejan, Michael R Savona, Alexander G Bick
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood cancer journal 14 (1) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid organ transplant recipients exhibit more TET2-mutant clonal hematopoiesis of indeterminate potential not driven by increased transplantation risk. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Taralynn M Mack, Caitlyn Vlasschaert, Kelly von Beck, Alexander James Silver, Jonathan Brett Heimlich, Hannah M Poisner, Henry Robert Condon, Jessica Ulloa, Andrew L Sochacki, Travis P Spaulding, Ashwin Kishtagari, Cosmin A Bejan, Yaomin Xu, Michael R Savona, Angela Jones, Alexander G Bick
Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics. medRxiv : the preprint server for health sciences (2023)
Caitlyn Vlasschaert, Taralynn M Mack, Jonathan Brett Heimlich, Abhishek Niroula, M D Mesbah Uddin, Joshua S Weinstock, Brian Sharber, Alexander James Silver, Yaomin Xu, Michael R Savona, Christopher J Gibson, Matthew B Lanktree, Michael J Rauh, Benjamin L Ebert, Pradeep Natarajan, Siddhartha Jaiswal, Alexander G Bick
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets. Blood (2023)
Caitlyn Vlasschaert, Taralynn M Mack, Jonathan Brett Heimlich, Abhishek Niroula, M D Mesbah Uddin, Joshua S Weinstock, Brian Sharber, Alexander James Silver, Yaomin Xu, Michael R Savona, Christopher J Gibson, Matthew B Lanktree, Michael J Rauh, Benjamin L Ebert, Pradeep Natarajan, Siddhartha Jaiswal, Alexander G Bick
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets. Blood (2023)
Philipp J Rauch, Jayakrishnan Gopakumar, Alexander James Silver, Daniel Nachun, Herra Ahmad, Marie McConkey, Tetsushi Nakao, Marc Bosse, Thiago Rentz, Nora Vivanco Gonzalez, Noah F Greenwald, Erin F McCaffrey, Zumana Khair, Manu Gopakumar, Kameron B Rodrigues, Amy E Lin, Eti Sinha, Maia Fefer, Drew N Cohen, Amélie Vromman, Eugenia Shvartz, Galina Sukhova, Sean Bendall, R Michael Angelo, Peter Libby, Benjamin L Ebert, Siddhartha Jaiswal
Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes. Nature cardiovascular research 2 (9) (2023)
Caitlyn Vlasschaert, Taralynn M Mack, Jonathan Brett Heimlich, Abhishek Niroula, M D Mesbah Uddin, Joshua S Weinstock, Brian Sharber, Alexander James Silver, Yaomin Xu, Michael R Savona, Christopher J Gibson, Matthew B Lanktree, Michael J Rauh, Benjamin L Ebert, Pradeep Natarajan, Siddhartha Jaiswal, Alexander G Bick
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets. Blood (2023)
Sakshi Jasra, Orsi Giricz, Rachel Zeig-Owens, Kith Pradhan, David G Goldfarb, Angelica Barreto-Galvez, Alexander James Silver, Jiahao Chen, Srabani Sahu, Shanisha Gordon-Mitchell, Gaurav S Choudhary, Srinivas Aluri, Tushar D Bhagat, Aditi Shastri, Cosmin A Bejan, Shannon S Stockton, Travis P Spaulding, Victor Thiruthuvanathan, Hiroki Goto, Jeannine Gerhardt, Syed Hissam Haider, Arul Veerappan, Matthias Bartenstein, George Nwankwo, Carl Ola Landgren, Michael D Weiden, Jacqueline Lekostaj, Ryan Bender, Frederick Fletcher, Lee Greenberger, Benjamin L Ebert, Ulrich Steidl, Britta Will, Anna Nolan, Advaitha Madireddy, Michael R Savona, David J Prezant, Amit K Verma
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster. Nature medicine 28 (3) (2022)
Andrew L Sochacki, Cosmin A Bejan, Shilin Zhao, Ameet Patel, Ashwin Kishtagari, Travis P Spaulding, Alexander James Silver, Shannon S Stockton, Kelly Pugh, Rodney Dixon Dorand, Manasa Ram Bhatta, Nicholas Strayer, Siwei Zhang, Christina A Snider, Thomas P Stricker, Aziz Nazha, Alexander G Bick, Yaomin Xu, Michael R Savona
Patient-specific comorbidities as prognostic variables for survival in myelofibrosis. Blood advances (2022)
Alexander James Silver, Alexander G Bick, Michael R Savona
Germline risk of clonal haematopoiesis. Nature reviews. Genetics 22 (9) (2021)
Ofir Wolach, Rob S Sellar, Kimberly Martinod, Deya Cherpokova, Marie McConkey, Ryan J Chappell, Alexander James Silver, Dylan Adams, Cecilia A Castellano, Rebekka K Schneider, Robert F Padera, Daniel J DeAngelo, Martha Wadleigh, David P Steensma, Ilene Galinsky, Richard M Stone, Giulio Genovese, Steven A McCarroll, Bozenna Iliadou, Christina M Hultman, Donna S Neuberg, Ann Mullally, Denisa D Wagner, Benjamin L Ebert
Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms. Science translational medicine 10 (436) (2019)

Alexander James Silver.css-eqlu8i{font-size:small;padding-left:4px;} (Alexander J Silver)

Publication Activity (10 Years)

Top Topics

Top Venues

Alexander James Silver (Alexander J Silver)