Hai Qian

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Topics

Tyrosine Kinase

Endoplasmic Reticulum

Top Venues

Journal of medicinal chemistry

Chemical biology & drug design

Biomaterials science

Expert opinion on therapeutic patents

This page only lists publications with an associated author ORCID identifier.

Publications

Yang Zhang, Yiqing Fan, Shuyu Liu, Yonghui Guan, Jiale Wan, Qiang Ren, Jialing Wang, Li Zhong, Zhipeng Hu, Wei Shi, Hai Qian
Development of Peptide Paratope Mimics Derived from the Anti-ROR1 Antibody and Long-Acting Peptide-Drug Conjugates for Targeted Cancer Therapy. Journal of medicinal chemistry 67 (13) (2024)
Yang Zhang, Yiqing Fan, Shuyu Liu, Yonghui Guan, Jiale Wan, Qiang Ren, Jialing Wang, Li Zhong, Zhipeng Hu, Wei Shi, Hai Qian
Development of Peptide Paratope Mimics Derived from the Anti-ROR1 Antibody and Long-Acting Peptide-Drug Conjugates for Targeted Cancer Therapy. Journal of medicinal chemistry 67 (13) (2024)
Yang Zhang, Yiqing Fan, Shuyu Liu, Yonghui Guan, Jiale Wan, Qiang Ren, Jialing Wang, Li Zhong, Zhipeng Hu, Wei Shi, Hai Qian
Development of Peptide Paratope Mimics Derived from the Anti-ROR1 Antibody and Long-Acting Peptide-Drug Conjugates for Targeted Cancer Therapy. Journal of medicinal chemistry (2024)
Wei Shi, Zhenzhen Tong, Shuang Chen, Qianqian Qiu, Jiaqi Zhou, Hai Qian
Development of novel self-assembled vaccines based on tumour-specific antigenic peptide and TLR2 agonist for effective breast cancer immunotherapy via activating CD8 + T cells and enhancing their function. Immunology (2023)
Qiang Ren, Yiqing Fan, Lixin Yang, Mayu Shan, Wei Shi, Hai Qian
An updated patent review of GPR40/ FFAR1 modulators (2020 - present). Expert opinion on therapeutic patents (2023)
Qianqian Qiu, Fanglian Chi, Daoguang Zhou, Zhancheng Xie, Yunxiao Liu, Hanyu Wu, Ziyu Yin, Wei Shi, Hai Qian
Exploration of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Bispecific Inhibitors Based on the Moiety of Fedratinib for Treatment of Both Hematologic Malignancies and Solid Cancers. Journal of medicinal chemistry (2023)
Chunxia Liu, Faisal Raza, Hai Qian, Xin Tian
Recent advances in poly(ionic liquid)s for biomedical application. Biomaterials science 10 (10) (2022)
Chunxia Liu, Bin Chen, Wei Shi, Wenlong Huang, Hai Qian
Ionic Liquids for Enhanced Drug Delivery: Recent Progress and Prevailing Challenges. Molecular pharmaceutics 19 (4) (2022)
Jiaqi Zhou, Xiaojian Bian, Zigui Kan, Zilong Cai, Yuxuan Jiang, Zike Wang, Yuanyuan Li, Wei Shi, Hai Qian
In Silico Exploration and Biological Evaluation of Bispecific Peptides Derived from Anti-HER2 Antibodies and Peptide-Camptothecin Conjugates for HER2-Positive Breast Cancer. Journal of medicinal chemistry 65 (22) (2022)
Di Li, Yuanxiang Tu, Kaijun Jin, Lingjun Duan, Yuan Hong, Jia Xu, Na Chen, Zhihui Zhang, Hongjian Zuo, Wanchun Gong, Jing Zhang, Qian Wang, Hai Qian, Xuenan Wang, Ying Ke, Guangxin Xia
Discovery of SPH5030, a Selective, Potent, and Irreversible Tyrosine Kinase Inhibitor for HER2-Amplified and HER2-Mutant Cancer Treatment. Journal of medicinal chemistry 65 (7) (2022)
Hao Zhang, Linghua Zhang, Yue Zhong, Jiaqi Zhou, Yuanyuan Li, Ping Zhang, Junting Xi, Wei Shi, Hai Qian
A radical photochromic metal-organic framework for boosting NIR-II photothermal conversion and therapy. Chemical communications (Cambridge, England) 58 (79) (2022)
Qianqian Qiu, Feng Zou, Huilan Li, Wei Shi, Daoguang Zhou, Ping Zhang, Teng Li, Ziyu Yin, Zilong Cai, Yuxuan Jiang, Wenlong Huang, Hai Qian
Structure-Based Discovery of Pyrimidine Aminobenzene Derivatives as Potent Oral Reversal Agents against P-gp- and BCRP-Mediated Multidrug Resistance. Journal of medicinal chemistry 64 (9) (2021)
Wei Shi, Qianqian Qiu, Ziying Feng, Zhenzhen Tong, Weiwei Guo, Feng Zou, Na Yue, Wenlong Huang, Hai Qian
Design, synthesis and immunological evaluation of self-assembled antigenic peptides from dual-antigen targets: a broad-spectrum candidate for an effective antibreast cancer therapy. Journal for immunotherapy of cancer 9 (6) (2021)
Jiuhui Li, Wenjie Zhang, Qianqian Qiu, Daoguang Zhou, Ziying Feng, Zhenzhen Tong, Jiaxin Wei, Wenlong Huang, Jieming Li, Hai Qian, Wei Shi
Design, synthesis, and biological evaluation of novel 4,4-difluoro-1-methyl-N, 6-diphenyl-5, 6-dihydro-4H-pyrimido [4, 5-b] [1, 2, 4] triazolo [4, 3-d] [1, 4] diazepin-8-amine derivatives as potential BRD4 inhibitors. Chemical biology & drug design 97 (5) (2021)
Yao Ma, Dawei Yin, Jingjia Ye, Xiduan Wei, Yameng Pei, Xueyuan Li, Guangxu Si, Xuan-Yu Chen, Zhe-Sheng Chen, Yi Dong, Feng Zou, Wei Shi, Qianqian Qiu, Hai Qian, Gang Liu
Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue. Journal of medicinal chemistry 63 (10) (2020)
Qianqian Qiu, Wei Shi, Shiyuan Zhao, Yan Zhu, Zhengquan Ding, Shaoyang Zhou, Mutta Kairuki, Wenlong Huang, Hai Qian
Discovery to solve multidrug resistance: Design, synthesis, and biological evaluation of novel agents. Archiv der Pharmazie 352 (10) (2019)
Chunxia Liu, Zheng Li, Wei Shi, Huilan Li, Nasi Wang, Yuxuan Dai, Chen Liao, Wenlong Huang, Hai Qian
Improving metabolic stability with deuterium: The discovery of HWL-066, a potent and long-acting free fatty acid receptor 1 agonists. Chemical biology & drug design 92 (2) (2018)
Jing Han, Feng Zhou, Yingying Fei, Xinyu Chen, Junjie Fu, Hai Qian
Preparation and Pharmaceutical Characterizations of Lipidated Dimeric Xenopus Glucagon-Like Peptide-1 Conjugates. Bioconjugate chemistry 29 (2) (2018)
Jieming Li, Yan Liu, Huilan Li, Wei Shi, Xinzhou Bi, Qianqian Qiu, Bo Zhang, Wenlong Huang, Hai Qian
pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications. Biomaterials science 6 (11) (2018)
Hesham Ghaleb, Huilan Li, Mutta Kairuki, Qianqian Qiu, Xinzhou Bi, Chunxia Liu, Chen Liao, Jieming Li, Kamal Hezam, Wenlong Huang, Hai Qian
Design, synthesis and evaluation of a novel series of inhibitors reversing P-glycoprotein-mediated multidrug resistance. Chemical biology & drug design 92 (3) (2018)
Qianqian Qiu, Wei Shi, Zheng Li, Bo Zhang, Miaobo Pan, Jian Cui, Yuxuan Dai, Wenlong Huang, Hai Qian
Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance. Journal of medicinal chemistry 60 (7) (2017)
Qianqian Qiu, Baomin Liu, Jian Cui, Zheng Li, Xin Deng, Hao Qiang, Jieming Li, Chen Liao, Bo Zhang, Wei Shi, Miaobo Pan, Wenlong Huang, Hai Qian
Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance. Journal of medicinal chemistry 60 (8) (2017)
Bo Zhang, Wei Shi, Jieming Li, Chen Liao, Limei Yang, Wenlong Huang, Hai Qian
Synthesis and biological evaluation of novel peptides based on antimicrobial peptides as potential agents with antitumor and multidrug resistance-reversing activities. Chemical biology & drug design 90 (5) (2017)
Wei Shi, Miaobo Pan, Hao Qiang, Qianqian Qiu, Wenlong Huang, Haiyan Lin, Hai Qian, Liang Ge
A novel mitochondria-targeting fluorescent probe for hydrogen sulfide in living cells. Chemical biology & drug design 90 (2) (2017)
Teng Cui, Juan-Juan Liang, Huan Chen, Dong-Dong Geng, Lei Jiao, Jian-Yong Yang, Hai Qian, Can Zhang, Ya Ding
Performance of Doxorubicin-Conjugated Gold Nanoparticles: Regulation of Drug Location. ACS applied materials & interfaces 9 (10) (2017)