Chemical biology & drug design

Keyphrases

Publications

volume 104, number 1, 2024

Yu Yang, Yamin Pu, Xiaoli Huang, Mengya Liao, Yiwen Zhang
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti-tumor activity. Chemical biology & drug design 104 (1) (2024)
Zijun Yan, Ting Yu, Xiaoping Wu, Mengyue Deng, Panpan Wei, Ning Su, Yuzhen Ding, Die Xia, Yuehui Zhang, Liangming Zhang, Tong Chen
Nanoemulsion based lipid nanoparticles for effective demethylcantharidin delivery to cure liver cancer. Chemical biology & drug design 104 (1) (2024)
Larissa R S P Baliza, Túlio R Freitas, Edward K S Gonçalves, Gabriel R Antunes, Ana J F Souza, Julliane Yoneda, Caique Lopes Duarte, Silmara N Andrade, Adriano de Paula Sabino, Fernando de Pilla Varotti, Diego P Sangi
Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals. Chemical biology & drug design 104 (1) (2024)
Nanting Zou, Runfang Wu, Zhao Wu, Chunfei Zhang, Haohong Zhang, Qingyan Mo, Mingqian Ju, Xinan Shi, Zewei Mao, Chunping Wan
MW-19, a dihydropyrazole derivative, induces human triple-negative breast cancer cell apoptosis by targeting apoptosis-related pathways. Chemical biology & drug design 104 (1) (2024)
Chujie Zhang, Juncong Ma, Chang Liu, Xianliang Yan
The protective effect of karanjin against sepsis-induced acute lung injury in mice is involved in the suppression of the TLR4 pathway. Chemical biology & drug design 104 (1) (2024)
Itzel Mercado-Sánchez, Julio López, Rogelio Chávez-Rocha, Ismael Vargas-Rodríguez, Adán Bazán-Jiménez, Mariana Segovia-Mendoza, Heriberto Prado-Garcia, Miguel A Vázquez, Rocío García-Becerra, Marco A Garcia-Revilla
Evaluation of doxorubicin and β-lapachone analogs as anticancer agents, a biological and computational study. Chemical biology & drug design 104 (1) (2024)
Izabela Czyżewska, Liliana Mazur, Łukasz Popiołek
Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review. Chemical biology & drug design 104 (1) (2024)
Zijun Yan, Ting Yu, Xiaoping Wu, Mengyue Deng, Panpan Wei, Ning Su, Yuzhen Ding, Die Xia, Yuehui Zhang, Liangming Zhang, Tong Chen
Nanoemulsion based lipid nanoparticles for effective demethylcantharidin delivery to cure liver cancer. Chemical biology & drug design 104 (1) (2024)
Bin Liu, Bowen Hou, Yu Zhao, Fengyi Gao, Xiaoyin Dong, Jiageng He
Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation. Chemical biology & drug design 104 (1) (2024)
Yasin Durkal, Kubilay Inci, Onur Tokgün, Uğur Yılmaz, Banu Candan Yılmaz
Integrative analysis of ex vivo studies and microarray reveals the novel inhibitor effects of trehalose on the pathogenesis of pterygium. Chemical biology & drug design 104 (1) (2024)
Swati Paliwal, Sandhya Bawa, Nishtha Shalmali, Rajiv K Tonk
Therapeutic potential and recent progression of BTK inhibitors against rheumatoid arthritis. Chemical biology & drug design 104 (1) (2024)
Elaine Soares Coimbra, Luciana M R Antinarelli, Ari Sérgio de Oliveira Lemos, Adolfo Firmino da Silva Neto, Alessandra Campbell Pinheiro, Marcus Vinícius Nora de Souza
Synthesis, biological evaluation and mechanism of action of benzothiazole derivatives with aromatic hydrazone moiety, a new class of antileishmanial compounds. Chemical biology & drug design 104 (1) (2024)
Mei Qian Yau, Angeline J Wan, Aaron S H Tiong, Yong Sheng Yiap, Jason Siau Ee Loo
Leveraging binding pose metadynamics to optimise target fishing predictions for three diverse ligands and their true targets. Chemical biology & drug design 104 (1) (2024)
Larissa R S P Baliza, Túlio R Freitas, Edward K S Gonçalves, Gabriel R Antunes, Ana J F Souza, Julliane Yoneda, Caique Lopes Duarte, Silmara N Andrade, Adriano de Paula Sabino, Fernando de Pilla Varotti, Diego P Sangi
Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals. Chemical biology & drug design 104 (1) (2024)
Jiangfei Liu, Yaohui Ni, Keyun Zhou, Guanzhao Wu, Liangyong Hu, Tianyu Zhu, Defeng Xu, Hang Hu
Synthesis of curcumin derivatives targeting androgen receptor for castration-resistant prostate cancer therapy. Chemical biology & drug design 104 (1) (2024)
Yu Yang, Yamin Pu, Xiaoli Huang, Mengya Liao, Yiwen Zhang
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti-tumor activity. Chemical biology & drug design 104 (1) (2024)
Itzel Mercado-Sánchez, Julio López, Rogelio Chávez-Rocha, Ismael Vargas-Rodríguez, Adán Bazán-Jiménez, Mariana Segovia-Mendoza, Heriberto Prado-Garcia, Miguel A Vázquez, Rocío García-Becerra, Marco A Garcia-Revilla
Evaluation of doxorubicin and β-lapachone analogs as anticancer agents, a biological and computational study. Chemical biology & drug design 104 (1) (2024)
Yinhui Qin, Yuetai Teng, Yan Yang, Zhenkun Mao, Shengyu Zhao, Na Zhang, Xu Li, Weihong Niu
Advancements in inhibitors of crucial enzymes in the cysteine biosynthetic pathway: Serine acetyltransferase and O-acetylserine sulfhydrylase. Chemical biology & drug design 104 (1) (2024)
Lina Jing, Chunxia Liu
Novel phenylpiperazine derivatives as potent transient receptor potential vanilloid 1 antagonists. Chemical biology & drug design 104 (1) (2024)
Mengke Sheng, Lina Ma, Zhixun Li, Xinhui Peng, Shuai Cen, Minfang Feng, Yuting Tian, Xingxing Dai, Xinyuan Shi
A hybrid evaluation of the intestinal absorption performance of compounds from molecular structure. Chemical biology & drug design 104 (1) (2024)

volume 104, number 2, 2024

Yulong Zhao, Zhoudong Zhang, Xiaotian Kong, Kai Wang, Yaxuan Wang, Jie Jia, Huanqiu Li, Sheng Tian
Prediction of Drug-Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches. Chemical biology & drug design 104 (2) (2024)
Mohammad Shimia, Monireh Amini, Armin Ostovar Ravari, Peyman Tabnak, Amir Valizadeh, Mohammad Ghaheri, Bahman Yousefi
Thymoquinone reversed doxorubicin resistance in U87 glioblastoma cells via targeting PI3K/Akt/mTOR signaling. Chemical biology & drug design 104 (2) (2024)
Lei Zhang, Xinliang Yang, Rui Yi, Siming Wu, Qianbin Li, Gaoyun Hu, Zhuo Chen
Design, Synthesis, and Biological Evaluation of Quinoline (Quinolinone) Derivatives as NADPH Oxidase (NOX) Inhibitors. Chemical biology & drug design 104 (2) (2024)
Wu Tao, Yu Xufeng, Chen Xianmei, Qu Mengrou, Wang Jieqiong, Qiao Mingqi
Exploring the Mechanism of Myrrh in the Treatment of Breast Cancer Based on Network Pharmacology and Cell Experiments. Chemical biology & drug design 104 (2) (2024)
Raveendra Madhukar Bhat, Venkatraman Hegde, Srinivasa Budagumpi, Vinayak Adimule, Rangappa S Keri
Benzimidazole-Oxadiazole Hybrids-Development in Medicinal Chemistry: An Overview. Chemical biology & drug design 104 (2) (2024)
Mohamed El Oirdi
Plumbagin's Antiproliferative Mechanism in Human Cancer Cells: A Copper-Dependent Cytotoxic Approach. Chemical biology & drug design 104 (2) (2024)
Jin-Rong Ni, Qun-Hu Zhang, Jie-Lin Deng, Hai-Hu Wang, Yong-Chi Duan, Cheng-Ji Zhang, Lue-Tao Jiang
Promotion Effect of Catalpol on Angiogenesis and Potential Mechanisms: A Research Based on Network Pharmacology. Chemical biology & drug design 104 (2) (2024)
Qingqing Yu, Rongjun Tang, Weixing Mo, Linfang Zhao, Lingdi Li
Baicalein Enhances Radiosensitivity in Colorectal Cancer via JAK2/STAT3 Pathway Inhibition. Chemical biology & drug design 104 (2) (2024)
Yijiao Huang, Pei Xiang, Yuanyuan Chen, Qi Pan, Kemiao Yuan
Alantolactone facilitates ferroptosis in non-small cell lung cancer through promoting FTH1 ubiquitination and degradation. Chemical biology & drug design 104 (2) (2024)
Jin-Rong Ni, Qun-Hu Zhang, Jie-Lin Deng, Hai-Hu Wang, Yong-Chi Duan, Cheng-Ji Zhang, Lue-Tao Jiang
Promotion Effect of Catalpol on Angiogenesis and Potential Mechanisms: A Research Based on Network Pharmacology. Chemical biology & drug design 104 (2) (2024)
Yanmei Du, Xiaojing Wang, Lihui Zhang, Hongyu Qin, Guangzhao Xu, Fahui Li, Chunyan Fang, Honggang Li, Lei Zhang
Structural modification of 2-phenylquinoline-4-carboxylic acid containing SIRT3 inhibitors for the cancer differentiation therapy. Chemical biology & drug design 104 (2) (2024)
Durga Bhavani Kundrapu, Amajala Krishna Chaitanya, Kothapalli Manaswi, Seema Kumari, RamaRao Malla
Quercetin and taxifolin inhibits TMPRSS2 activity and its interaction with EGFR in paclitaxel-resistant breast cancer cells: An in silico and in vitro study. Chemical biology & drug design 104 (2) (2024)
Xiaoyan Lu, Yanzhong Han, Yongkang Zhang, Rui Li, Jiaoyan Xu, Jian Yang, Jingchun Yao, Zhihai Lv
An integrated network pharmacology and molecular docking approach to reveal the role of Arctigenin against Cutibacterium acnes-induced skin inflammation by targeting the CYP19A1. Chemical biology & drug design 104 (2) (2024)
Vinod Ravasaheb Shinde, Sajmina Khatun, Ajinkya Madhukar Thanekar, Basu Bhattacharjee, Aravind Kumar Rengan
Sodium copper chlorophyllin-loaded chitosan nanoparticle-based photodynamic therapy for B16 melanoma cancer cells. Chemical biology & drug design 104 (2) (2024)
Mine Buga Aktekin, Zehra Oksuz, Burcin Turkmenoglu, Erman Salih Istifli, Mehmet Kuzucu, Oztekin Algul
Synthesis and evaluation of di-heterocyclic benzazole compounds as potential antibacterial and anti-biofilm agents against Staphylococcus aureus. Chemical biology & drug design 104 (2) (2024)
Vinod Ravasaheb Shinde, Sajmina Khatun, Ajinkya Madhukar Thanekar, Basu Bhattacharjee, Aravind Kumar Rengan
Sodium copper chlorophyllin-loaded chitosan nanoparticle-based photodynamic therapy for B16 melanoma cancer cells. Chemical biology & drug design 104 (2) (2024)

volume 104, number 3, 2024

Ashini Singh, Suman Sinha, Niraj Kumar Singh
Dietary Natural Flavonoids: Intervention for MAO-B Against Parkinson's Disease. Chemical biology & drug design 104 (3) (2024)
Jian Guo, Huiheng Qu, Zhigang Huang, Yu Xue
Puerarin Decreases the Expression of FUS-Dependent MAPK4 to Inhibit the Development of Triple-Negative Breast Cancer. Chemical biology & drug design 104 (3) (2024)
Neha Sharma, Rupa Mazumder, Pallavi Rai, Abhijit Debnath
Role of PD-1 in Skin Cancer: Molecular Mechanism, Clinical Applications, and Resistance. Chemical biology & drug design 104 (3) (2024)
Hongbo Li, Xingen Liao, Min Lan, Jianying He, Jingping Gao, Zhiqiang Fan, Jiayu Huang, Xin Wu, Jiaxin Chen, Guicai Sun
Arctigenin Modulates Adipogenic-Osteogenic Balance in the Bone Marrow Microenvironment of Ovariectomized Rats via the MEK1/PPARγ/Wnt/β-Catenin Pathway. Chemical biology & drug design 104 (3) (2024)
Yawen Chen, Hongshun Gu, Danni Ye, Yi Li, Yan Chen, Haoyi Qiao, Yujiao Huang, Ran Tao, Shuhui Yu, Jianjun Zhang, Wenting Fei, Linyuan Wang
NMC-4 Ameliorates Depression-Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress. Chemical biology & drug design 104 (3) (2024)
Nurul Alam Inayatsyah, Mohamad Jemain Mohamad Ridhwan, Alim Alsukor Aznirulhisham, Nurulfazlina Edayah Rasol, Noraini Kasim, Syahrul Imran Abu Bakar
Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α-Glucosidase Inhibitor and Their Molecular Docking Studies. Chemical biology & drug design 104 (3) (2024)
Esra Kaplan, Ziya Erdem Koc, Ahmet Uysal, Abdullahi Ibrahim Uba, Gokhan Zengin
Elucidation of the Microwave-Assisted Synthesis and Characterization of Heteronuclear Complexes of Bisbenzimidazole Derivatives and Their Biological Activities by In Vitro and In Silico Assays. Chemical biology & drug design 104 (3) (2024)
Monica Chauhan, Rahul Barot, Rasana Yadav, Karan Joshi, Sadaf Mirza, Rupesh Chikhale, Vijay Kumar Srivastava, Mange Ram Yadav, Prashant R Murumkar
The Mycobacterium tuberculosis Cell Wall: An Alluring Drug Target for Developing Newer Anti-TB Drugs-A Perspective. Chemical biology & drug design 104 (3) (2024)
Anna Smirnova, Elena V Tretyakova, Oxana B Kazakova
New Cytotoxic α-Aminoacylamide and bis-1,5-Disubstituted Tetrazole Adducts From Amino-Diterpene Molecules by Ugi Reaction. Chemical biology & drug design 104 (3) (2024)
Ruihan Zhao, Xiao Ni, Chenhu Dong, Jun Xu, Yu Zhao
Synthesis and Preliminary Anticancer Evaluation of 4-C Derivatives of Diphyllin. Chemical biology & drug design 104 (3) (2024)
Weili Wang, Yuxiao Tang, Xiaobin Zhuo, Jianxin Yang, Zelong Gao, Chenqi Li, Chenghua Wu, Jianxin Qian, Feng Xie, Hui Shen, Dongyao Wang
Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells. Chemical biology & drug design 104 (3) (2024)
Qianrong Zhang, Aiping Jin, Haijuan Cheng, Shulin Li, Wei Li
Fucoxanthin Attenuates Myocardial Ischemia/Reperfusion-Induced Injury via AMPK/GSK-3β/Nrf2 Axis. Chemical biology & drug design 104 (3) (2024)
Ye-Jun Yang, Juan Liu
Echinacoside Alleviates Carbon Tetrachloride-Induced Chronic Liver Injury by Modulating the NF-κB/NLRP3 Inflammasome Pathway. Chemical biology & drug design 104 (3) (2024)
He Yu, Junsheng Lou, Libin Ni, Minwei Yan, Kewu Zhu, Su Mao, Jungao Zhu
Isoquercetin Ameliorates Osteoarthritis via Nrf2/NF-κB Axis: An In Vitro and In Vivo Study. Chemical biology & drug design 104 (3) (2024)