Henry I Mosberg

Publication Activity (10 Years)

Years Active: 2017-2020
Publications (10 Years): 8

Top Topics

Prefrontal Cortex

Pain Management

Structure Activity Relationship

Molecular Docking

Top Venues

Journal of medicinal chemistry

ACS chemical neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Zoe M Koeperich, Mark D Ericson, Katie T Freeman, Robert C Speth, Irina D Pogozheva, Henry I Mosberg, Carrie Haskell-Luevano
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists. Journal of medicinal chemistry 63 (5) (2020)
Sean Henry, Jessica P Anand, Ashley C Brinkel, Douglas M McMillan, Jack J Twarozynski, Christian E Loo, John R Traynor, Henry I Mosberg
SAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore. ACS chemical neuroscience 12 (1) (2020)
Sean Henry, Jessica P Anand, Jack J Twarozynski, Ashley C Brinkel, Irina D Pogozheva, Bryan F Sears, Emily M Jutkiewicz, John R Traynor, Henry I Mosberg
Aromatic-Amine Pendants Produce Highly Potent and Efficacious Mixed Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Peptidomimetics with Enhanced Metabolic Stability. Journal of medicinal chemistry 63 (4) (2020)
Deanna Montgomery, Jessica P Anand, Nicholas W Griggs, Thomas J Fernandez, Joshua G Hartman, Ashley A Sánchez-Santiago, Irina D Pogozheva, John R Traynor, Henry I Mosberg
Novel Dimethyltyrosine-Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show in Vitro Kappa and Mu Opioid Receptor Agonism. ACS chemical neuroscience 10 (8) (2019)
Sean P Henry, Thomas J Fernandez, Jessica P Anand, Nicholas W Griggs, John R Traynor, Henry I Mosberg
Structural Simplification of a Tetrahydroquinoline-Core Peptidomimetic μ-Opioid Receptor (MOR) Agonist/δ-Opioid Receptor (DOR) Antagonist Produces Improved Metabolic Stability. Journal of medicinal chemistry 62 (8) (2019)
Anthony F Nastase, Jessica P Anand, Aaron M Bender, Deanna Montgomery, Nicholas W Griggs, Thomas J Fernandez, Emily M Jutkiewicz, John R Traynor, Henry I Mosberg
Dual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design. Journal of medicinal chemistry 62 (8) (2019)
Anthony F Nastase, Nicholas W Griggs, Jessica P Anand, Thomas J Fernandez, Aubrie A Harland, Tyler J Trask, Emily M Jutkiewicz, John R Traynor, Henry I Mosberg
Synthesis and Pharmacological Evaluation of Novel C-8 Substituted Tetrahydroquinolines as Balanced-Affinity Mu/Delta Opioid Ligands for the Treatment of Pain. ACS chemical neuroscience 9 (7) (2018)
Aubrie A Harland, Irina D Pogozheva, Nicholas W Griggs, Tyler J Trask, John R Traynor, Henry I Mosberg
Placement of Hydroxy Moiety on Pendant of Peptidomimetic Scaffold Modulates Mu and Kappa Opioid Receptor Efficacy. ACS chemical neuroscience 8 (11) (2017)