Carrie Haskell-Luevano

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Topics

Obsessive Compulsive Disorder

Cervical Cancer Screening

Top Venues

Journal of medicinal chemistry

ACS chemical neuroscience

ACS pharmacology & translational science

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Mark D Ericson, Katie T Freeman, Courtney M Larson, Jacob L Bouchard, Kristen John, Mary M Lunzer, Zoe M Koeperich, Carrie Haskell-Luevano
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS pharmacology & translational science 7 (4) (2024)
Maria-Jesus Blanco, Joanne J Bronson, Erin F DiMauro, Carolyn D Dzierba, MariJean Eggen, Amanda L Garner, Gunda I Georg, Jeanine Giarolla, Nicole C Goodwin, Melissa C Grenier-Davies, Carrie Haskell-Luevano, Gerhard Bringmann, Rong Huang, H Rachel Lagiakos, Katerina Leftheris, Yvonne Martin, Maria João Matos, Tricia L May-Dracka, Christa Elisabeth Müller, Amy Hauck Newman, Emma Parmee, Jennifer C Petter, Nuria A Tamayo, Ruth R Wexler, Maria Laura Bolognesi, Amy Ripka, Wendy B Young
Empowering Voices: Inspiring Women in Medicinal Chemistry. ACS medicinal chemistry letters 15 (4) (2024)
Mark D Ericson, Katie T Freeman, Courtney M Larson, Jacob L Bouchard, Kristen John, Mary M Lunzer, Zoe M Koeperich, Carrie Haskell-Luevano
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS pharmacology & translational science 7 (4) (2024)
Mark D Ericson, Katie T Freeman, Courtney M Larson, Jacob L Bouchard, Kristen John, Mary M Lunzer, Zoe M Koeperich, Carrie Haskell-Luevano
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS pharmacology & translational science 7 (4) (2024)
Maria-Jesus Blanco, Joanne J Bronson, Erin F DiMauro, Carolyn D Dzierba, MariJean Eggen, Amanda L Garner, Gunda I Georg, Jeanine Giarolla, Nicole C Goodwin, Melissa C Grenier-Davies, Carrie Haskell-Luevano, Gerhard Bringmann, Rong Huang, H Rachel Lagiakos, Katerina Leftheris, Yvonne Martin, Maria João Matos, Tricia L May-Dracka, Christa Elisabeth Müller, Amy Hauck Newman, Emma Parmee, Jennifer C Petter, Nuria A Tamayo, Ruth R Wexler, Maria Laura Bolognesi, Amy Ripka, Wendy B Young
Empowering Voices: Inspiring Women in Medicinal Chemistry. Journal of medicinal chemistry 67 (6) (2024)
Nicholas A Weirath, Carrie Haskell-Luevano
Recommended Tool Compounds for the Melanocortin Receptor (MCR) G Protein-Coupled Receptors (GPCRs). ACS pharmacology & translational science 7 (9) (2024)
Maria-Jesus Blanco, Joanne J Bronson, Erin F DiMauro, Carolyn D Dzierba, MariJean Eggen, Amanda L Garner, Gunda I Georg, Jeanine Giarolla, Nicole C Goodwin, Melissa C Grenier-Davies, Carrie Haskell-Luevano, Gerhard Bringmann, Rong Huang, H Rachel Lagiakos, Katerina Leftheris, Yvonne Martin, Maria João Matos, Tricia L May-Dracka, Christa Elisabeth Müller, Amy Hauck Newman, Emma Parmee, Jennifer C Petter, Nuria A Tamayo, Ruth R Wexler, Maria Laura Bolognesi, Amy Ripka, Wendy B Young
Empowering Voices: Inspiring Women in Medicinal Chemistry. Journal of medicinal chemistry 67 (6) (2024)
Maria-Jesus Blanco, Joanne J Bronson, Erin F DiMauro, Carolyn D Dzierba, MariJean Eggen, Amanda L Garner, Gunda I Georg, Jeanine Giarolla, Nicole C Goodwin, Melissa C Grenier-Davies, Carrie Haskell-Luevano, Gerhard Bringmann, Rong Huang, H Rachel Lagiakos, Katerina Leftheris, Yvonne Martin, Maria João Matos, Tricia L May-Dracka, Christa Elisabeth Müller, Amy Hauck Newman, Emma Parmee, Jennifer C Petter, Nuria A Tamayo, Ruth R Wexler, Maria Laura Bolognesi, Amy Ripka, Wendy B Young
Empowering Voices: Inspiring Women in Medicinal Chemistry. ACS medicinal chemistry letters 15 (4) (2024)
Maria-Jesus Blanco, Joanne J Bronson, Erin F DiMauro, Carolyn D Dzierba, MariJean Eggen, Amanda L Garner, Gunda I Georg, Jeanine Giarolla, Nicole C Goodwin, Melissa C Grenier-Davies, Carrie Haskell-Luevano, Gerhard Bringmann, Rong Huang, H Rachel Lagiakos, Katerina Leftheris, Yvonne Martin, Maria João Matos, Tricia L May-Dracka, Christa Elisabeth Müller, Amy Hauck Newman, Emma Parmee, Jennifer C Petter, Nuria A Tamayo, Ruth R Wexler, Maria Laura Bolognesi, Amy Ripka, Wendy B Young
Empowering Voices: Inspiring Women in Medicinal Chemistry. Journal of medicinal chemistry (2024)
Mark D Ericson, Katie T Freeman, Travis M LaVoi, Haley M Donow, Radleigh G Santos, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten, Carrie Haskell-Luevano
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands. International journal of molecular sciences 24 (12) (2023)
Mark D Ericson, Linh T Tran, Sarah S Mathre, Katie T Freeman, Kelsey Holdaway, Kristen John, Mary M Lunzer, Jacob L Bouchard, Carrie Haskell-Luevano
Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH 2 ] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2')-Arg-NH 2 ]. Journal of medicinal chemistry (2023)
Mark D Ericson, Katie T Freeman, Travis M LaVoi, Haley M Donow, Radleigh G Santos, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten, Carrie Haskell-Luevano
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands. International journal of molecular sciences 24 (12) (2023)
Skye R Doering, Katie Freeman, Ginamarie Debevec, Phaedra Geer, Radleigh G Santos, Travis M Lavoi, Marc A Giulianotti, Clemencia Pinilla, Jon R Appel, Richard A Houghten, Mark D Ericson, Carrie Haskell-Luevano
Correction to "Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign". Journal of medicinal chemistry (2023)
Mark D Ericson, Katie T Freeman, Travis M LaVoi, Haley M Donow, Radleigh G Santos, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten, Carrie Haskell-Luevano
The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands. International journal of molecular sciences 24 (12) (2023)
Mark D Ericson, Courtney M Larson, Katie T Freeman, Lennart Nicke, Armin Geyer, Carrie Haskell-Luevano
Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide. ACS omega 7 (31) (2022)
Skye R Doering, Katie Freeman, Ginamarie Debevec, Phaedra Geer, Radleigh G Santos, Travis M Lavoi, Marc A Giulianotti, Clemencia Pinilla, Jon R Appel, Richard A Houghten, Mark D Ericson, Carrie Haskell-Luevano
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign. Journal of medicinal chemistry 64 (9) (2021)
Mark D Ericson, Erica M Haslach, Sathya M Schnell, Katie T Freeman, Zhimin M Xiang, Frederico P Portillo, Robert Speth, Sally A Litherland, Carrie Haskell-Luevano
Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R. ACS chemical neuroscience 12 (3) (2021)
Mark D Ericson, Skye R Doering, Courtney M Larson, Katie T Freeman, Travis M LaVoi, Haley M Donow, Radleigh G Santos, Rachel H Cho, Zoe M Koeperich, Marc A Giulianotti, Clemencia Pinilla, Richard A Houghten, Carrie Haskell-Luevano
Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist. Journal of medicinal chemistry 64 (19) (2021)
Zoe M Koeperich, Mark D Ericson, Katie T Freeman, Robert C Speth, Irina D Pogozheva, Henry I Mosberg, Carrie Haskell-Luevano
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists. Journal of medicinal chemistry 63 (5) (2020)
Danielle N Adank, Mary M Lunzer, Mark D Ericson, Zoe M Koeperich, Stacey L Wilber, Katlyn A Fleming, Carrie Haskell-Luevano
Comparative Intracerebroventricular and Intrathecal Administration of a Nanomolar Macrocyclic Melanocortin Receptor Agonist MDE6-5-2c (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro]) Decreases Food Intake in Mice. ACS chemical neuroscience 11 (19) (2020)
Katherine N Schlasner, Mark D Ericson, Skye R Doering, Katie T Freeman, Mary Weinrich, Carrie Haskell-Luevano
Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(pI)DPhe-Tic-NH2 at the Mouse Melanocortin Receptors: Modification at the (pI)DPhe Position Leads to mMC3R Versus mMC4R Selective Ligands. Molecules (Basel, Switzerland) 24 (8) (2019)
Katlyn A Fleming, Katie T Freeman, Mike D Powers, Radleigh G Santos, Ginamarie Debevec, Marc A Giulianotti, Richard A Houghten, Skye R Doering, Clemencia Pinilla, Carrie Haskell-Luevano
Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist. Journal of medicinal chemistry 62 (5) (2019)
Mark D Ericson, Anamika Singh, Srinivasa R Tala, Erica M Haslach, Marvin L S Dirain, Jay W Schaub, Viktor Flores, Natalie Eick, Cody J Lensing, Katie T Freeman, Branden A Smeester, Danielle N Adank, Stacey L Wilber, Robert Speth, Carrie Haskell-Luevano
Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors. Journal of medicinal chemistry 61 (8) (2018)
Cody J Lensing, Katie T Freeman, Sathya M Schnell, Robert C Speth, Adam T Zarth, Carrie Haskell-Luevano
Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin Receptors. Journal of medicinal chemistry 62 (1) (2018)
Carrie Haskell-Luevano, Gunda I Georg, Shaomeng Wang, Nicholas A Meanwell
Allosteric Modulators of Drug Targets Special Issue. Journal of medicinal chemistry 61 (4) (2018)
Katlyn A Fleming, Mark D Ericson, Katie T Freeman, Danielle N Adank, Mary M Lunzer, Stacey L Wilber, Carrie Haskell-Luevano
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in Mice. ACS chemical neuroscience 9 (5) (2018)
Aleksandar Todorovic, Cody J Lensing, Jerry Ryan Holder, Joseph W Scott, Nicholas B Sorensen, Carrie Haskell-Luevano
Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His-dPhe-Arg-Trp-NH2 Template. ACS chemical neuroscience 9 (11) (2018)
Mark D Ericson, Zoe M Koerperich, Katie T Freeman, Katlyn A Fleming, Carrie Haskell-Luevano
Arg-Phe-Phe d-Amino Acid Stereochemistry Scan in the Macrocyclic Agouti-Related Protein Antagonist Scaffold c[Pro-Arg-Phe-Phe-Xxx-Ala-Phe-DPro] Results in Unanticipated Melanocortin-1 Receptor Agonist Profiles. ACS chemical neuroscience 9 (12) (2018)
Mark D Ericson, Carrie Haskell-Luevano
A Review of Single-Nucleotide Polymorphisms in Orexigenic Neuropeptides Targeting G Protein-Coupled Receptors. ACS chemical neuroscience 9 (6) (2018)
Srinivasa R Tala, Anamika Singh, Cody J Lensing, Sathya M Schnell, Katie T Freeman, James R Rocca, Carrie Haskell-Luevano
1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional Characterization. ACS chemical neuroscience 9 (5) (2018)
Katlyn A Fleming, Katie T Freeman, Mark D Ericson, Carrie Haskell-Luevano
Synergistic Multiresidue Substitutions of a Macrocyclic c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Agouti-Related Protein (AGRP) Scaffold Yield Potent and >600-Fold MC4R versus MC3R Selective Melanocortin Receptor Antagonists. Journal of medicinal chemistry 61 (17) (2018)
Cody J Lensing, Danielle N Adank, Stacey L Wilber, Katie T Freeman, Sathya M Schnell, Robert C Speth, Adam T Zarth, Carrie Haskell-Luevano
A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage. ACS chemical neuroscience 8 (6) (2017)
Danielle N Adank, Mary M Lunzer, Cody J Lensing, Stacey L Wilber, Amy M Gancarz, Carrie Haskell-Luevano
Comparative in Vivo Investigation of Intrathecal and Intracerebroventricular Administration with Melanocortin Ligands MTII and AGRP into Mice. ACS chemical neuroscience 9 (2) (2017)
Mark D Ericson, Katie T Freeman, Sathya M Schnell, Carrie Haskell-Luevano
A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands. Journal of medicinal chemistry 60 (2) (2017)
Mark D Ericson, Katie T Freeman, Sathya M Schnell, Katlyn A Fleming, Carrie Haskell-Luevano
Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor. Journal of medicinal chemistry 60 (19) (2017)
Skye R Doering, Katie T Freeman, Sathya M Schnell, Erica M Haslach, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh G Santos, Marc A Giulianotti, Clemencia Pinilla, Jon R Appel, Robert C Speth, Richard A Houghten, Carrie Haskell-Luevano
Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2. Journal of medicinal chemistry 60 (10) (2017)