Hequan Yao

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 45

Top Topics

Molecular Docking

Cell Cycle Arrest

High Resolution Mass Spectrometry

Respiratory Syndrome Coronavirus

Top Venues

Organic letters

The Journal of organic chemistry

Future medicinal chemistry

Chemical communications (Cambridge, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Hengrui Zhou, Yiji Xue, Xiang Zhou, Hequan Yao, Aijun Lin
Palladium-Catalyzed Asymmetric Desymmetrization for the Simultaneous Construction of Chiral Phosphorus and Quaternary Carbon Stereocenters. Organic letters 26 (28) (2024)
Hengrui Zhou, Yiji Xue, Xiang Zhou, Hequan Yao, Aijun Lin
Palladium-Catalyzed Asymmetric Desymmetrization for the Simultaneous Construction of Chiral Phosphorus and Quaternary Carbon Stereocenters. Organic letters (2024)
Yong Yan, Hanwen Liu, Di Wu, Zhihao Gu, Wenhao Guo, Hequan Yao, Kejiang Lin, Xuanyi Li
Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2. Future medicinal chemistry 16 (9) (2024)
Yong Yan, Hanwen Liu, Di Wu, Zhihao Gu, Wenhao Guo, Hequan Yao, Kejiang Lin, Xuanyi Li
Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2. Future medicinal chemistry 16 (9) (2024)
Yong Yan, Hanwen Liu, Di Wu, Zhihao Gu, Wenhao Guo, Hequan Yao, Kejiang Lin, Xuanyi Li
Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2. Future medicinal chemistry (2024)
Yong Yan, Hanwen Liu, Di Wu, Zhihao Gu, Wenhao Guo, Hequan Yao, Kejiang Lin, Xuanyi Li
Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2. Future medicinal chemistry 16 (9) (2024)
Yong Yan, Hanwen Liu, Di Wu, Zhihao Gu, Wenhao Guo, Hequan Yao, Kejiang Lin, Xuanyi Li
Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2. Future medicinal chemistry 16 (9) (2024)
Pengyun Liu, Hongyue Dong, Baihui Gong, Shang Gao, Aijun Lin, Hequan Yao
Palladium-Catalyzed Asymmetric Tandem Carbonylation-Heck Reaction of Cyclopentenes to Access Chiral Bicyclo[3.2.1]octenes. Organic letters (2024)
Haipin Zhou, Rui Pan, Menghua Xu, Jiao Ma, Aijun Lin, Hequan Yao
Construction of oxygenated 2-azabicyclo[2.2.1]heptanes via palladium-catalyzed 1,2-aminoacyloxylation of cyclopentenes. Chemical communications (Cambridge, England) 59 (24) (2023)
Haipin Zhou, Rui Pan, Menghua Xu, Jiao Ma, Aijun Lin, Hequan Yao
Construction of oxygenated 2-azabicyclo[2.2.1]heptanes via palladium-catalyzed 1,2-aminoacyloxylation of cyclopentenes. Chemical communications (Cambridge, England) 59 (24) (2023)
Xinnan Li, Xiaotong Ze, Shengnan Zhou, Zhaoxin Hu, Chen He, Yilin Jia, Lihua Liu, Tao Wang, Junda Li, Shengtao Xu, Dong-Hua Yang, Zhe-Sheng Chen, Hequan Yao, Jinyi Xu, Hong Yao
Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA Polymerase. Journal of medicinal chemistry (2023)
Haipin Zhou, Rui Pan, Menghua Xu, Jiao Ma, Aijun Lin, Hequan Yao
Construction of oxygenated 2-azabicyclo[2.2.1]heptanes via palladium-catalyzed 1,2-aminoacyloxylation of cyclopentenes. Chemical communications (Cambridge, England) (2023)
Min Cai, Jiao Ma, Qimin Wu, Aijun Lin, Hequan Yao
Enantioselective Syntheses of 2-Azabicyclo[2.2.1]heptanes via Brønsted Acid Catalyzed Ring-Opening of meso -Epoxides. Organic letters (2022)
Bo Li, Jianping Zhu, Xia Zheng, Wenqing Ti, Yue Huang, Hequan Yao
Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones. The Journal of organic chemistry 88 (1) (2022)
Meihui Wang, Bo Li, Baihui Gong, Hequan Yao, Aijun Lin
Synthesis of pyranopyrazoles with a chiral quaternary carbon stereocenter via copper-catalyzed enantioselective [3 + 3] cycloaddition. Chemical communications (Cambridge, England) 58 (17) (2022)
Bo Li, Jianping Zhu, Xia Zheng, Wenqing Ti, Yue Huang, Hequan Yao
Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones. The Journal of organic chemistry (2022)
Long Chen, Cong Shi, Wei Li, Bo Li, Jie Zhu, Aijun Lin, Hequan Yao
Palladium-Catalyzed Asymmetric C-C Bond Activation/Carbonylation of Cyclobutanones. Organic letters (2022)
Qiuyu Li, Yunchu Zhang, Yuye Zeng, Yujing Fan, Aijun Lin, Hequan Yao
Palladium-Catalyzed Asymmetric Dearomative Carbonylation of Indoles. Organic letters 24 (16) (2022)
Qiuyu Li, Xinxin Fang, Rui Pan, Hequan Yao, Aijun Lin
Palladium-Catalyzed Asymmetric Sequential Hydroamination of 1,3-Enynes: Enantioselective Syntheses of Chiral Imidazolidinones. Journal of the American Chemical Society 144 (25) (2022)
Bo Li, Jianping Zhu, Xia Zheng, Wenqing Ti, Yue Huang, Hequan Yao
Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones. The Journal of organic chemistry 88 (1) (2022)
Bo Li, Jianping Zhu, Xia Zheng, Wenqing Ti, Yue Huang, Hequan Yao
Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones. The Journal of organic chemistry 88 (1) (2022)
Xiaoyi Zhu, Ruibo Li, Hequan Yao, Aijun Lin
Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds. Organic letters 23 (12) (2021)
Qiuyu Li, Rui Pan, Meihui Wang, Hequan Yao, Aijun Lin
Ligand-Controlled, Palladium-Catalyzed Asymmetric [4+4] and [2+4] Cycloadditions. Organic letters 23 (6) (2021)
Siwei Chen, Min Cai, Junru Huang, Hequan Yao, Aijun Lin
Cobalt-Catalyzed Dearomatization of Indoles via Transfer Hydrogenation To Afford Polycyclic Indolines. Organic letters 23 (6) (2021)
Dongquan Zhang, Miaomiao Li, Jiajia Li, Aijun Lin, Hequan Yao
Rhodium-catalyzed intermolecular enantioselective Alder-ene type reaction of cyclopentenes with silylacetylenes. Nature communications 12 (1) (2021)
Zhenbo Yuan, Yuye Zeng, Ziwen Feng, Zhe Guan, Aijun Lin, Hequan Yao
Constructing chiral bicyclo[3.2.1]octanes via palladium-catalyzed asymmetric tandem Heck/carbonylation desymmetrization of cyclopentenes. Nature communications 11 (1) (2020)
Songjin Guo, Panpan Li, Zhe Guan, Libo Cai, Siwei Chen, Aijun Lin, Hequan Yao
Pd-Catalyzed Alkyne Insertion/C-H Activation/[4 + 2] Carboannulation of Alkenes to the Synthesis of Polycyclics. Organic letters 21 (4) (2019)
Zhenbo Yuan, Ziwen Feng, Yuye Zeng, Xiaobin Zhao, Aijun Lin, Hequan Yao
Palladium-Catalyzed Asymmetric Intramolecular Reductive Heck Desymmetrization of Cyclopentenes: Access to Chiral Bicyclo[3.2.1]octanes. Angewandte Chemie (International ed. in English) 58 (9) (2019)
Rui Pan, Cong Shi, Dongquan Zhang, Yang Tian, Songjin Guo, Hequan Yao, Aijun Lin
Nickel-Catalyzed Reductive 1,2-Dialkynylation of Alkenes Bearing an 8-Aminoquinoline Directing Group. Organic letters 21 (22) (2019)
Songjin Guo, Rui Pan, Zhe Guan, Panpan Li, Libo Cai, Siwei Chen, Aijun Lin, Hequan Yao
Synthesis of Indole-Fused Polycyclics via Rhodium-Catalyzed Undirected C-H Activation/Alkene Insertion. Organic letters 21 (16) (2019)
Zhe Guan, Siwei Chen, Yue Huang, Hequan Yao
Rhodium(III)-Catalyzed Intramolecular Olefin Hydroarylation of Aromatic Aldehydes Using a Transient Directing Group. Organic letters 21 (11) (2019)
Xiaoying Xu, Kaifan Zhang, Panpan Li, Hequan Yao, Aijun Lin
[3 + 3] Cycloaddition of Azides with in Situ Formed Azaoxyallyl Cations To Synthesize 1,2,3,4-Tetrazines. Organic letters 20 (7) (2018)
Yanpeng Liu, Honghao Sun, Zhangjian Huang, Cong Ma, Aijun Lin, Hequan Yao, Jinyi Xu, Shengtao Xu
Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water. The Journal of organic chemistry 83 (23) (2018)
Xinxin Fang, Yuye Zeng, Qiuyu Li, Zijun Wu, Hequan Yao, Aijun Lin
Redox-Neutral Atom-Economic Pd(0)-Catalyzed Dearomatization of β-Naphthols with Alkynes toward Naphthalenones. Organic letters 20 (9) (2018)
Rui Pan, Lingyin Hu, Chunhua Han, Aijun Lin, Hequan Yao
Cascade Radical 1,6-Addition/Cyclization of para-Quinone Methides: Leading to Spiro[4.5]deca-6,9-dien-8-ones. Organic letters 20 (7) (2018)
Kai Yuan, Lina Liu, Jiayi Chen, Songjin Guo, Hequan Yao, Aijun Lin
Palladium-Catalyzed Cascade Heck Cyclization To Access Bisindoles. Organic letters 20 (12) (2018)
Xinxin Fang, Qiuyu Li, Rui Shi, Hequan Yao, Aijun Lin
Controllable Pd-Catalyzed Allylation of Indoles with Skipped Enynes: Divergent Synthesis of Indolenines and N-Allylindoles. Organic letters 20 (19) (2018)
Shengtao Xu, Hong Yao, Shanshan Luo, Yun-Kai Zhang, Dong-Hua Yang, Dahong Li, Guangyu Wang, Mei Hu, Yangyi Qiu, Xiaoming Wu, Hequan Yao, Weijia Xie, Zhe-Sheng Chen, Jinyi Xu
A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway. Journal of medicinal chemistry 60 (4) (2017)
Kaifan Zhang, Xiaoying Xu, Jiuan Zheng, Hequan Yao, Yue Huang, Aijun Lin
[3 + 3] Cycloaddition of in Situ Formed Azaoxyallyl Cations with 2-Alkenylindoles: An Approach to Tetrahydro-β-carbolinones. Organic letters 19 (10) (2017)
Shang Gao, Hao Liu, Chi Yang, Zhiyuan Fu, Hequan Yao, Aijun Lin
Accessing 1,3-Dienes via Palladium-Catalyzed Allylic Alkylation of Pronucleophiles with Skipped Enynes. Organic letters 19 (18) (2017)
Jiuan Zheng, Panpan Li, Meng Gu, Aijun Lin, Hequan Yao
Synthesis of Spiropentadiene Pyrazolones by Rh(III)-Catalyzed Formal sp3 C-H Activation/Annulation. Organic letters 19 (11) (2017)
Xuanyi Li, Chunhua Han, Hequan Yao, Aijun Lin
Organocatalyzed [3 + 2] Annulation of Cyclopropenones and β-Ketoesters: An Approach to Substituted Butenolides with a Quaternary Center. Organic letters 19 (4) (2017)
Shengtao Xu, Hong Yao, Mei Hu, Dahong Li, Zheying Zhu, Weijia Xie, Hequan Yao, Liang Wu, Zhe-Sheng Chen, Jinyi Xu
6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents. Journal of natural products 80 (9) (2017)
Zhenbo Yuan, Lina Liu, Rui Pan, Hequan Yao, Aijun Lin
Silver-Catalyzed Cascade 1,6-Addition/Cyclization of para-Quinone Methides with Propargyl Malonates: An Approach to Spiro[4.5]deca-6,9-dien-8-ones. The Journal of organic chemistry 82 (16) (2017)
Peng Sun, Shang Gao, Chi Yang, Songjin Guo, Aijun Lin, Hequan Yao
Controllable Rh(III)-Catalyzed Annulation between Salicylaldehydes and Diazo Compounds: Divergent Synthesis of Chromones and Benzofurans. Organic letters 18 (24) (2016)