Jinyi Xu

中国科学家在线 ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 53

Top Topics

Signaling Pathway

Top Venues

Journal of medicinal chemistry

The Journal of organic chemistry

Future medicinal chemistry

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Yiping Duan, Zhichao Guo, Tiandong Zheng, Yang Lu, Jinyi Xu, Jie Liu, Fulai Yang
Iodine-Promoted Reductive Sulfenylation Using Ketones as Hydride Donors. The Journal of organic chemistry 89 (8) (2024)
Yiping Duan, Zhichao Guo, Tiandong Zheng, Yang Lu, Jinyi Xu, Jie Liu, Fulai Yang
Iodine-Promoted Reductive Sulfenylation Using Ketones as Hydride Donors. The Journal of organic chemistry (2024)
Xiuyuan Wu, Xiaotong Ze, Shuai Qin, Beiyu Zhang, Xinnan Li, Qi Gong, Haiyan Zhang, Zheying Zhu, Jinyi Xu
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease. Molecules (Basel, Switzerland) 29 (8) (2024)
Shengnan Zhou, Xiaotong Ze, Dazhi Feng, Lihua Liu, Yuning Shi, Minghui Yu, Lijuan Huang, Yunyue Wang, Hanlu Men, Jianbing Wu, Zhenwei Yuan, Mengze Zhou, Jinyi Xu, Xinnan Li, Hong Yao
Identification of 6-Fluorine-Substituted Coumarin Analogues as POLRMT Inhibitors with High Potency and Safety for Treatment of Pancreatic Cancer. Journal of medicinal chemistry 67 (15) (2024)
Shengnan Zhou, Xiaotong Ze, Dazhi Feng, Lihua Liu, Yuning Shi, Minghui Yu, Lijuan Huang, Yunyue Wang, Hanlu Men, Jianbing Wu, Zhenwei Yuan, Mengze Zhou, Jinyi Xu, Xinnan Li, Hong Yao
Identification of 6-Fluorine-Substituted Coumarin Analogues as POLRMT Inhibitors with High Potency and Safety for Treatment of Pancreatic Cancer. Journal of medicinal chemistry (2024)
Xiuyuan Wu, Xiaotong Ze, Shuai Qin, Beiyu Zhang, Xinnan Li, Qi Gong, Haiyan Zhang, Zheying Zhu, Jinyi Xu
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease. Molecules (Basel, Switzerland) 29 (8) (2024)
Peng Wang, Huajian Zhu, Jia-Sheng Tian, Wenjian Zhu, Shengtao Xu, Hong Yao, Jie Liu, Zheying Zhu, Chao-Yu Miao, Jinyi Xu
Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension. Journal of medicinal chemistry (2024)
Chen He, Junkai Liu, Junda Li, Hongyu Wu, Chenyang Jiao, Xiaotong Ze, Shengtao Xu, Zheying Zhu, Wenjie Guo, Jinyi Xu, Hong Yao
Hit-to-Lead Optimization of the Natural Product Oridonin as Novel NLRP3 Inflammasome Inhibitors with Potent Anti-Inflammation Activity. Journal of medicinal chemistry (2024)
Chen He, Junkai Liu, Junda Li, Hongyu Wu, Chenyang Jiao, Xiaotong Ze, Shengtao Xu, Zheying Zhu, Wenjie Guo, Jinyi Xu, Hong Yao
Hit-to-Lead Optimization of the Natural Product Oridonin as Novel NLRP3 Inflammasome Inhibitors with Potent Anti-Inflammation Activity. Journal of medicinal chemistry 67 (11) (2024)
Shengnan Zhou, Xiaotong Ze, Dazhi Feng, Lihua Liu, Yuning Shi, Minghui Yu, Lijuan Huang, Yunyue Wang, Hanlu Men, Jianbing Wu, Zhenwei Yuan, Mengze Zhou, Jinyi Xu, Xinnan Li, Hong Yao
Identification of 6-Fluorine-Substituted Coumarin Analogues as POLRMT Inhibitors with High Potency and Safety for Treatment of Pancreatic Cancer. Journal of medicinal chemistry 67 (15) (2024)
Haoxiang Weng, Jinlong Li, Huajian Zhu, Kei Fung Carver Wong, Zheying Zhu, Jinyi Xu
An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors. Future medicinal chemistry 15 (1) (2023)
Shaowen Xie, Feiyan Zhan, Jingjie Zhu, Yuan Sun, Huajian Zhu, Jie Liu, Jian Chen, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Hong Yao, Jinyi Xu, Shengtao Xu
Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie (International ed. in English) 62 (13) (2023)
Shaowen Xie, Feiyan Zhan, Jingjie Zhu, Yuan Sun, Huajian Zhu, Jie Liu, Jian Chen, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Hong Yao, Jinyi Xu, Shengtao Xu
Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie (International ed. in English) 62 (13) (2023)
Wenjian Zhu, Hongyu Wu, Chen He, Huajian Zhu, Hong Yao, Yun Cao, Yueman Shi, Xiaotong Chen, Xue Feng, Shengtao Xu, Zheying Zhu, Jinyi Xu
Discovery of novel β-elemene hybrids with hydrogen sulfide-releasing moiety possessing cardiovascular protective activity for the treatment of atherosclerosis. RSC medicinal chemistry 15 (1) (2023)
Yiping Duan, Wenyi Zhong, Zhaolan Zeng, Jiajie Feng, Jinyi Xu, Fulai Yang, Jie Liu
Iodine-promoted transfer of dihydrogen from ketones to alkenes, triphenylmethyl, and diphenylmethyl derivatives. Chemical communications (Cambridge, England) (2023)
Shaowen Xie, Feiyan Zhan, Jingjie Zhu, Yuan Sun, Huajian Zhu, Jie Liu, Jian Chen, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Hong Yao, Jinyi Xu, Shengtao Xu
Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie (International ed. in English) 62 (13) (2023)
Wenjian Zhu, Hongyu Wu, Chen He, Huajian Zhu, Hong Yao, Yun Cao, Yueman Shi, Xiaotong Chen, Xue Feng, Shengtao Xu, Zheying Zhu, Jinyi Xu
Discovery of novel β-elemene hybrids with hydrogen sulfide-releasing moiety possessing cardiovascular protective activity for the treatment of atherosclerosis. RSC medicinal chemistry 15 (1) (2023)
Shaowen Xie, Feiyan Zhan, Jingjie Zhu, Yuan Sun, Huajian Zhu, Jie Liu, Jian Chen, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Hong Yao, Jinyi Xu, Shengtao Xu
Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie (International ed. in English) (2023)
Haoxiang Weng, Jinlong Li, Huajian Zhu, Kei Fung Carver Wong, Zheying Zhu, Jinyi Xu
An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors. Future medicinal chemistry (2023)
Xinnan Li, Xiaotong Ze, Shengnan Zhou, Zhaoxin Hu, Chen He, Yilin Jia, Lihua Liu, Tao Wang, Junda Li, Shengtao Xu, Dong-Hua Yang, Zhe-Sheng Chen, Hequan Yao, Jinyi Xu, Hong Yao
Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA Polymerase. Journal of medicinal chemistry (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry 88 (6) (2023)
Shaowen Xie, Feiyan Zhan, Jingjie Zhu, Yuan Sun, Huajian Zhu, Jie Liu, Jian Chen, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Hong Yao, Jinyi Xu, Shengtao Xu
Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie (International ed. in English) 62 (13) (2023)
Haoxiang Weng, Jinlong Li, Huajian Zhu, Kei Fung Carver Wong, Zheying Zhu, Jinyi Xu
An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors. Future medicinal chemistry 15 (1) (2023)
Haoxiang Weng, Jinlong Li, Huajian Zhu, Kei Fung Carver Wong, Zheying Zhu, Jinyi Xu
An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors. Future medicinal chemistry 15 (1) (2023)
Shaowen Xie, Jingjie Zhu, Junda Li, Feiyan Zhan, Hong Yao, Jinyi Xu, Shengtao Xu
Small-Molecule Hydrophobic Tagging: A Promising Strategy of Druglike Technology for Targeted Protein Degradation. Journal of medicinal chemistry (2023)
Zhaoxin Hu, Shengnan Zhou, Junda Li, Xinnan Li, Yang Zhou, Zheying Zhu, Jinyi Xu, Jie Liu
Design, synthesis and biological evaluation of novel indanones derivatives as potent acetylcholinesterase/monoamine oxidase B inhibitors. Future medicinal chemistry (2023)
Haoxiang Weng, Jinlong Li, Huajian Zhu, Kei Fung Carver Wong, Zheying Zhu, Jinyi Xu
An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors. Future medicinal chemistry 15 (1) (2023)
Songtao Xue, Zhiwei Li, Xiaotong Ze, Xiuyuan Wu, Chen He, Wen Shuai, Maria Marlow, Jian Chen, David J Scurr, Zheying Zhu, Jinyi Xu, Shengtao Xu
Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation. Journal of medicinal chemistry (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry 88 (6) (2023)
Giuseppe Uras, Xinuo Li, Alessia Manca, Antonella Pantaleo, Marco Bo, Jinyi Xu, Stephanie Allen, Zheying Zhu
Development of p-Tau Differentiated Cell Model of Alzheimer's Disease to Screen Novel Acetylcholinesterase Inhibitors. International journal of molecular sciences 23 (23) (2022)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Cu(II) Complexes with Proline-Derived Schiff Base Ligand: Chemical Resolution of N , C -Unprotected α-Amino Acids and Their Antibacterial Activity. The Journal of organic chemistry 87 (19) (2022)
Yin Yuan, Hong Yao, Manzhen Zhou, Xiaoqian Ma, Yi Zhou, Jinyi Xu, Miao-Miao Niu, Jun Yin, Lufeng Zheng, Shengtao Xu
Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization. Journal of medicinal chemistry 65 (23) (2022)
Huajian Zhu, Yuchen Tan, Chen He, Yang Liu, Yiping Duan, Wenjian Zhu, Tiandong Zheng, Da-Hong Li, Jinyi Xu, Dong-Hua Yang, Zhe-Sheng Chen, Shengtao Xu
Discovery of a Novel Vascular Disrupting Agent Inhibiting Tubulin Polymerization and HDACs with Potent Antitumor Effects. Journal of medicinal chemistry 65 (16) (2022)
Xinnan Li, Tiantian Li, Feiyan Zhan, Feiyue Cheng, Li Lu, Bocheng Zhang, Junda Li, Zhaoxin Hu, Shengnan Zhou, Yilin Jia, Stephanie Allen, Lisa Jane White, James Phillips, Zheying Zhu, Jinyi Xu, Hequan Yao
Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease. ACS chemical neuroscience 13 (23) (2022)
Giuseppe Uras, Xinuo Li, Alessia Manca, Antonella Pantaleo, Marco Bo, Jinyi Xu, Stephanie Allen, Zheying Zhu
Development of p-Tau Differentiated Cell Model of Alzheimer's Disease to Screen Novel Acetylcholinesterase Inhibitors. International journal of molecular sciences 23 (23) (2022)
Giuseppe Uras, Xinuo Li, Alessia Manca, Antonella Pantaleo, Marco Bo, Jinyi Xu, Stephanie Allen, Zheying Zhu
Development of p-Tau Differentiated Cell Model of Alzheimer's Disease to Screen Novel Acetylcholinesterase Inhibitors. International journal of molecular sciences 23 (23) (2022)
Giuseppe Uras, Xinuo Li, Alessia Manca, Antonella Pantaleo, Marco Bo, Jinyi Xu, Stephanie Allen, Zheying Zhu
Development of p-Tau Differentiated Cell Model of Alzheimer's Disease to Screen Novel Acetylcholinesterase Inhibitors. International journal of molecular sciences 23 (23) (2022)
Jichao Chen, Yiping Duan, Xiaoxuan Yu, Jiarou Zhong, Jing Bai, Nian-Guang Li, Zheying Zhu, Jinyi Xu
Development of novel 9- O -substituted-13-octylberberine derivatives as potential anti-hepatocellular carcinoma agents. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Shengtao Xu, Hong Yao, Yangyi Qiu, Manzhen Zhou, Da-Hong Li, Liang Wu, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu
Discovery of Novel Polycyclic Heterocyclic Derivatives from Evodiamine for the Potential Treatment of Triple-Negative Breast Cancer. Journal of medicinal chemistry 64 (23) (2021)
Shaowen Xie, Yuan Sun, Yulin Liu, Xinnan Li, Xinuo Li, Wenyi Zhong, Feiyan Zhan, Jingjie Zhu, Hong Yao, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu, Shengtao Xu
Development of Alectinib-Based PROTACs as Novel Potent Degraders of Anaplastic Lymphoma Kinase (ALK). Journal of medicinal chemistry 64 (13) (2021)
Hong Yao, Giuseppe Uras, Pengfei Zhang, Shengtao Xu, Ying Yin, Jie Liu, Shuai Qin, Xinuo Li, Stephanie Allen, Renren Bai, Qi Gong, Hai Yan Zhang, Zheying Zhu, Jinyi Xu
Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry 64 (11) (2021)
Hong Yao, Shaowen Xie, Xiaoqian Ma, Junkai Liu, Hongyu Wu, Aijun Lin, Hequan Yao, Da-Hong Li, Shengtao Xu, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu
Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer. Journal of medicinal chemistry 63 (15) (2020)
Yanpeng Liu, Lixue Lu, Haipin Zhou, Feijie Xu, Cong Ma, Zhangjian Huang, Jinyi Xu, Shengtao Xu
Chemodivergent synthesis of N -(pyridin-2-yl)amides and 3-bromoimidazo[1,2- a ]pyridines from α-bromoketones and 2-aminopyridines. RSC advances 9 (59) (2019)
Tianyu Wang, Xiaoxing Wu, Changying Guo, Kuojun Zhang, Jinyi Xu, Zheng Li, Sheng Jiang
Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway. Journal of medicinal chemistry 62 (4) (2018)
Yu Zou, Di Zhao, Chang Yan, Yanpeng Ji, Jin Liu, Jinyi Xu, Yisheng Lai, Jide Tian, Yihua Zhang, Zhangjian Huang
Novel Ligustrazine-Based Analogs of Piperlongumine Potently Suppress Proliferation and Metastasis of Colorectal Cancer Cells in Vitro and in Vivo. Journal of medicinal chemistry 61 (5) (2018)
Yanpeng Liu, Honghao Sun, Zhangjian Huang, Cong Ma, Aijun Lin, Hequan Yao, Jinyi Xu, Shengtao Xu
Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water. The Journal of organic chemistry 83 (23) (2018)
Pengfei Zhang, Yu Zhou, Xu Han, Jinyi Xu, Hong Liu
N-Heterocyclic Carbene Catalyzed Enantioselective [3 + 2] Dearomatizing Annulation of Saturated Carboxylic Esters with N-Iminoisoquinolinium Ylides. The Journal of organic chemistry 83 (7) (2018)
Wenlong Li, Feijie Xu, Wen Shuai, Honghao Sun, Hong Yao, Cong Ma, Shengtao Xu, Hequan Yao, Zheying Zhu, Dong-Hua Yang, Zhe-Sheng Chen, Jinyi Xu
Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity. Journal of medicinal chemistry 62 (2) (2018)
Shengtao Xu, Guangyu Wang, Feijie Xu, Wenlong Li, Aijun Lin, Hequan Yao, Jinyi Xu
Concise Total Synthesis of (±)-Deguelin and (±)-Tephrosin Using a Vinyl Iodide as a Key Building Block. Journal of natural products 81 (4) (2018)
Shengtao Xu, Hong Yao, Shanshan Luo, Yun-Kai Zhang, Dong-Hua Yang, Dahong Li, Guangyu Wang, Mei Hu, Yangyi Qiu, Xiaoming Wu, Hequan Yao, Weijia Xie, Zhe-Sheng Chen, Jinyi Xu
A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway. Journal of medicinal chemistry 60 (4) (2017)
Jia Wang, Chaolei Wang, Zheng Wu, Xinnan Li, Shengtao Xu, Jie Liu, Qinying Lan, Zheying Zhu, Jinyi Xu
Design, synthesis, biological evaluation, and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors (part II). Chemical biology & drug design 91 (3) (2017)
Shengtao Xu, Hong Yao, Mei Hu, Dahong Li, Zheying Zhu, Weijia Xie, Hequan Yao, Liang Wu, Zhe-Sheng Chen, Jinyi Xu
6,7-Seco-ent-Kauranoids Derived from Oridonin as Potential Anticancer Agents. Journal of natural products 80 (9) (2017)