Ira Tabas

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 21

Top Topics

Skeletal Muscle

Top Venues

Nature metabolism

Science translational medicine

Science signaling

Nature reviews. Cardiology

This page only lists publications with an associated author ORCID identifier.

Publications

Santosh R Sukka, Patrick B Ampomah, Lancia N F Darville, David Ngai, Xiaobo Wang, George Kuriakose, Yuling Xiao, Jin-Jun Shi, John M Koomen, Robert H McCusker, Ira Tabas
Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution. Nature metabolism (2024)
Mary P Moore, Xiaobo Wang, John Paul Kennelly, Hongxue Shi, Yuki Ishino, Kuniyuki Kano, Junken Aoki, Alessandro Cherubini, Luisa Ronzoni, Xiuqing Guo, Naga P Chalasani, Shareef Khalid, Danish Saleheen, Matthew A Mitsche, Jerome I Rotter, Katherine P Yates, Luca Valenti, Nozomu Kono, Peter Tontonoz, Ira Tabas
Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation. Hepatology (Baltimore, Md.) (2024)
Santosh R Sukka, Patrick B Ampomah, Lancia N F Darville, David Ngai, Xiaobo Wang, George Kuriakose, Yuling Xiao, Jin-Jun Shi, John M Koomen, Robert H McCusker, Ira Tabas
Publisher Correction: Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution. Nature metabolism (2024)
Wen Dai, Heng Zhang, Hayley Lund, Ziyu Zhang, Mark Castleberry, Maya Rodriguez, George Kuriakose, Sweta Gupta, Magdalena Lewandowska, Hayley R Powers, Swati Valmiki, Jieqing Zhu, Amy D Shapiro, M Mahmood Hussain, José A López, Mary G Sorci-Thomas, Roy L Silverstein, Henry N Ginsberg, Daisy Sahoo, Ira Tabas, Ze Zheng
Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes. Science (New York, N.Y.) 381 (6661) (2023)
Maaike Schilperoort, David Ngai, Santosh R Sukka, Kleopatra Avrampou, Hongxue Shi, Ira Tabas
The role of efferocytosis-fueled macrophage metabolism in the resolution of inflammation. Immunological reviews (2023)
Maaike Schilperoort, David Ngai, Marina Katerelos, David A Power, Ira Tabas
PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages. Nature metabolism (2023)
Maaike Schilperoort, David Ngai, Marina Katerelos, David A Power, Ira Tabas
PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages. Nature metabolism (2023)
David Ngai, Maaike Schilperoort, Ira Tabas
Efferocytosis-induced lactate enables the proliferation of pro-resolving macrophages to mediate tissue repair. Nature metabolism (2023)
Ingmar Mederacke, Aveline Filliol, Silvia Affo, Bindu Nair, Celine Hernandez, Qiuyan Sun, Florian Hamberger, Francesco Brundu, Yu Chen, Aashreya Ravichandra, Peter Huebener, Helena Anke, Hongxue Shi, Raquel A Martínez García de la Torre, James R Smith, Neil Cowan Henderson, Florian W R Vondran, Carla V Rothlin, Heike Bähre, Ira Tabas, Pau Sancho-Bru, Robert F Schwabe
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver. Science translational medicine 14 (639) (2022)
Hongxue Shi, Xiaobo Wang, Fang Li, Brennan D Gerlach, Arif Yurdagul, Mary P Moore, Sharon Zeldin, Hanrui Zhang, Bishuang Cai, Ze Zheng, Luca Vittorio Valenti, Ira Tabas
CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis. Science translational medicine 14 (672) (2022)
Patrick B Ampomah, Bishuang Cai, Santosh R Sukka, Brennan D Gerlach, Arif Yurdagul, Xiaobo Wang, George Kuriakose, Lancia N F Darville, Yan Sun, Simone Sidoli, John M Koomen, Alan R Tall, Ira Tabas
Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. Nature metabolism 4 (4) (2022)
Lale Ozcan, Canan Kasikara, Arif Yurdagul, George Kuriakose, Brian Hubbard, Michael H Serrano-Wu, Ira Tabas
Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis. PloS one 16 (5) (2021)
Wei Chen, Maaike Schilperoort, Yihai Cao, Jin-Jun Shi, Ira Tabas, Wei Tao
Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis. Nature reviews. Cardiology (2021)
Junjie Yu, Changyu Zhu, Xiaobo Wang, KyeongJin Kim, Alberto Bartolomé, Paola Dongiovanni, Katherine P Yates, Luca Vittorio Valenti, Michele Carrer, Thorsten Sadowski, Li Qiang, Ira Tabas, Joel E Lavine, Utpal B Pajvani
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis. Science translational medicine 13 (599) (2021)
Wei Tao, Arif Yurdagul, Na Kong, Wenliang Li, Xiaobo Wang, Amanda C Doran, Chan Feng, Junqing Wang, Mohammad Ariful Islam, Omid C Farokhzad, Ira Tabas, Jin-Jun Shi
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice. Science translational medicine 12 (553) (2021)
Changyu Zhu, Ira Tabas, Robert F Schwabe, Utpal B Pajvani
Maladaptive regeneration - the reawakening of developmental pathways in NASH and fibrosis. Nature reviews. Gastroenterology & hepatology 18 (2) (2020)
Amanda C Doran, Arif Yurdagul, Ira Tabas
Efferocytosis in health and disease. Nature reviews. Immunology 20 (4) (2019)
Xiaobo Wang, Mark R Sommerfeld, Kerstin Jahn-Hofmann, Bishuang Cai, Aveline Filliol, Helen E Remotti, Robert F Schwabe, Aimo Kannt, Ira Tabas
A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice. Hepatology communications 3 (9) (2019)
Changyu Zhu, KyeongJin Kim, Xiaobo Wang, Alberto Bartolomé, Marcela Salomao, Paola Dongiovanni, Marica Meroni, Mark J Graham, Katherine P Yates, Anna Mae Diehl, Robert F Schwabe, Ira Tabas, Luca Vittorio Valenti, Joel E Lavine, Utpal B Pajvani
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis. Science translational medicine 10 (468) (2019)
Ze Zheng, Lalitha Nayak, Wei Wang, Arif Yurdagul, Xiaobo Wang, Bishuang Cai, Stephanie Lapping, Lale Ozcan, Rajasekhar Ramakrishnan, Richard G Pestell, Mukesh K Jain, Ira Tabas
An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. Blood 133 (7) (2018)
Bishuang Cai, Canan Kasikara, Amanda C Doran, Rajasekhar Ramakrishnan, Raymond B Birge, Ira Tabas
MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Science signaling 11 (549) (2018)