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John M Koomen (John Koomen)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 40

Top Venues

ACS chemical biology

Nature communications

Nature cancer

Cancer research

H Lee Moffitt Cancer Center and Research Institute

Texas A&M University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

H Lee Moffitt Cancer Center and Research Institute

United States

Faculty Member-Currently Associate Level :: Molecular Oncology

Education History

Texas A&M University

United States

PHD :: Chemistry

Publications

Yi Liao, Sean Chin Chan, Eric A Welsh, Bin Fang, Luxin Sun, Ernst K Schonbrunn, John M Koomen, Derek R Duckett, Eric B Haura, Andrii Monastyrskyi, Uwe Rix
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target. ACS chemical biology 18 (2) (2023)
Karen L Burger, Mario R Fernandez, Mark B Meads, Praneeth Reddy Sudalagunta, Paula S Oliveira, Rafael Renatino Canevarolo, Raghunandan Reddy Alugubelli, Alexandre Tungsevik, Gabe De Avila, Maria Silva, Allison I Graeter, Hongyue Dai, Nicole D Vincelette, Antony Prabhu, Dario Magaletti, Chunying Yang, Weimin Li, Amit Kulkarni, Oliver Alexander Hampton, John M Koomen, William R Roush, Andrii Monastyrskyi, Anders E Berglund, Ariosto S Silva, John L Cleveland, Kenneth H Shain
CK1δ/CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma. Cancer research (2023)
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin R Luo, Tiandao Li, John M Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y Feng, Kiran Mahajan, Nupam P Mahajan
Author Correction: Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. Nature communications 14 (1) (2023)
Daniel K Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B Williamson, Dennie T Frederick, Tatyana Sharova, Michael G White, Joseph Markowitz, Biwei Cao, Jonathan V Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos Moran Segura, Jane Messina, Kerry L Thomas, Lancia Darville, Victoria Izumi, John M Koomen, Shari A Pilon-Thomas, Brian Ruffell, Vincent C Luca, Robert S Haltiwanger, Xuefeng Wang, Jennifer A Wargo, Genevieve Marie Boland, Eric K Lau
Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Nature cancer 4 (2) (2023)
Daniel K Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B Williamson, Dennie T Frederick, Tatyana Sharova, Michael G White, Joseph Markowitz, Biwei Cao, Jonathan V Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos Moran Segura, Jane Messina, Kerry L Thomas, Lancia Darville, Victoria Izumi, John M Koomen, Shari A Pilon-Thomas, Brian Ruffell, Vincent C Luca, Robert S Haltiwanger, Xuefeng Wang, Jennifer A Wargo, Genevieve Marie Boland, Eric K Lau
Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Nature cancer 4 (2) (2023)
Sudhir Putty Reddy, Aileen Y Alontaga, Eric A Welsh, Eric B Haura, Theresa A Boyle, Steven A Eschrich, John M Koomen
Deciphering Phenotypes from Protein Biomarkers for Translational Research with PIPER. Journal of proteome research (2023)
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin R Luo, Tiandao Li, John M Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y Feng, Kiran Mahajan, Nupam P Mahajan
Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. Nature communications 14 (1) (2023)
Yi Liao, Sean Chin Chan, Eric A Welsh, Bin Fang, Luxin Sun, Ernst K Schonbrunn, John M Koomen, Derek R Duckett, Eric B Haura, Andrii Monastyrskyi, Uwe Rix
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target. ACS chemical biology (2023)
Yi Liao, Sean Chin Chan, Eric A Welsh, Bin Fang, Luxin Sun, Ernst K Schonbrunn, John M Koomen, Derek R Duckett, Eric B Haura, Andrii Monastyrskyi, Uwe Rix
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target. ACS chemical biology 18 (2) (2023)
Yi Liao, Sean Chin Chan, Eric A Welsh, Bin Fang, Luxin Sun, Ernst K Schonbrunn, John M Koomen, Derek R Duckett, Eric B Haura, Andrii Monastyrskyi, Uwe Rix
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target. ACS chemical biology 18 (2) (2023)
Daniel K Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B Williamson, Dennie T Frederick, Tatyana Sharova, Michael G White, Joseph Markowitz, Biwei Cao, Jonathan V Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos Moran Segura, Jane Messina, Kerry L Thomas, Lancia Darville, Victoria Izumi, John M Koomen, Shari A Pilon-Thomas, Brian Ruffell, Vincent C Luca, Robert S Haltiwanger, Xuefeng Wang, Jennifer A Wargo, Genevieve Marie Boland, Eric K Lau
Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Nature cancer (2023)
Michael F Emmons, Richard L Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Chao Zhang, Robert J B Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M Koomen, Jiannong Li, Yian Ann Chen, Peter A Forsyth, Jonathan D Licht, Keiran S M Smalley
HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. Nature communications 14 (1) (2023)
Daniel K Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B Williamson, Dennie T Frederick, Tatyana Sharova, Michael G White, Joseph Markowitz, Biwei Cao, Jonathan V Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos Moran Segura, Jane Messina, Kerry L Thomas, Lancia Darville, Victoria Izumi, John M Koomen, Shari A Pilon-Thomas, Brian Ruffell, Vincent C Luca, Robert S Haltiwanger, Xuefeng Wang, Jennifer A Wargo, Genevieve Marie Boland, Eric K Lau
Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Nature cancer 4 (2) (2023)
Yi Liao, Sean Chin Chan, Eric A Welsh, Bin Fang, Luxin Sun, Ernst K Schonbrunn, John M Koomen, Derek R Duckett, Eric B Haura, Andrii Monastyrskyi, Uwe Rix
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target. ACS chemical biology 18 (2) (2023)
Karen E Ross, Guolin Zhang, Cuneyt Akcora, Yu Lin, Bin Fang, John M Koomen, Eric B Haura, Mark Grimes
Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer. PLoS computational biology 19 (3) (2023)
Daniel K Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B Williamson, Dennie T Frederick, Tatyana Sharova, Michael G White, Joseph Markowitz, Biwei Cao, Jonathan V Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos Moran Segura, Jane Messina, Kerry L Thomas, Lancia Darville, Victoria Izumi, John M Koomen, Shari A Pilon-Thomas, Brian Ruffell, Vincent C Luca, Robert S Haltiwanger, Xuefeng Wang, Jennifer A Wargo, Genevieve Marie Boland, Eric K Lau
Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Nature cancer 4 (2) (2023)
Rebecca S Hesterberg, Min Liu, Aya G Elmarsafawi, John M Koomen, Eric A Welsh, Stephen G Hesterberg, Sujeewa Ranatunga, Chunying Yang, Weimin Li, Harshani R Lawrence, Paulo C Rodriguez, Anders E Berglund, John L Cleveland
TCR-Independent Metabolic Reprogramming Precedes Lymphoma-Driven Changes in T-cell Fate. Cancer immunology research 10 (10) (2022)
Shikha Mahajan, Anurima Majumder, Paul A Stewart, Yian Ann Chen, Emma Adhikari, Bin Fang, Yan Yang, Harshani R Lawrence, Fumi Kinose, John M Koomen, Eric B Haura
Deubiquitinase Vulnerabilities Identified through Activity-Based Protein Profiling in Non-Small Cell Lung Cancer. ACS chemical biology 17 (4) (2022)
Lily L Remsing Rix, Natalia J Sumi, Qianqian Hu, Bina Desai, Annamarie T Bryant, Xueli Li, Eric A Welsh, Bin Fang, Fumi Kinose, Brent M Kuenzi, Yian Ann Chen, Scott J Antonia, Christine M Lovly, John M Koomen, Eric B Haura, Andriy Marusyk, Uwe Rix
IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells. Science signaling 15 (747) (2022)
Mario R Fernandez, Franz X Schaub, Chunying Yang, Weimin Li, Seongseok Yun, Stephanie K Schaub, Frank C Dorsey, Min Liu, Meredith A Steeves, Andrea Ballabio, Alexandar Tzankov, Zhihua Chen, John M Koomen, Anders E Berglund, John L Cleveland
Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy. Cancer research 82 (7) (2022)
Anurima Majumder, Sina Hosseinian, Mia Stroud, Emma Adhikari, James J Saller, Matthew A Smith, Guolin Zhang, Shruti Agarwal, Marc Creixell, Benjamin S Meyer, Fumi Kinose, Kiah Bowers, Bin Fang, Paul Allen Stewart, Eric A Welsh, Theresa A Boyle, Aaron S Meyer, John M Koomen, Eric B Haura
Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration. Molecular cancer research : MCR 20 (4) (2022)
Patrick B Ampomah, Bishuang Cai, Santosh R Sukka, Brennan D Gerlach, Arif Yurdagul, Xiaobo Wang, George Kuriakose, Lancia N F Darville, Yan Sun, Simone Sidoli, John M Koomen, Alan R Tall, Ira Tabas
Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. Nature metabolism 4 (4) (2022)
Jiannong Li, Inna Smalley, Zhihua Chen, Jheng-Yu Wu, Manali S Phadke, Jamie K Teer, Thanh Nguyen, Florian A Karreth, John M Koomen, Amod A Sarnaik, Jonathan S Zager, Nikhil I Khushalani, Ahmad A Tarhini, Vernon K Sondak, Paulo C Rodriguez, Jane L Messina, Yian Ann Chen, Keiran S M Smalley
Single-cell Characterization of the Cellular Landscape of Acral Melanoma Identifies Novel Targets for Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (10) (2022)
Asmaa El-Kenawi, William Dominguez-Viqueira, Min Liu, Shivanshu Awasthi, Julieta Abraham-Miranda, Aysenur Keske, KayLee K Steiner, Leenil Noel, Amparo N Serna, Jasreman Dhillon, Robert James Gillies, Xiaoqing Yu, John M Koomen, Kosj Yamoah, Robert A Gatenby, Brian Ruffell
Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer. Cancer research 81 (21) (2021)
Aslamuzzaman Kazi, Liwei Chen, Shengyan Xiang, Rajanikanth Vangipurapu, Hua Yang, Francisca Beato, Bin Fang, Terence M Williams, Kazim Husain, Patrick W Underwood, Jason B Fleming, Mokenge Malafa, Eric A Welsh, John M Koomen, José Trevino, Saïd M Sebti
Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (14) (2021)
Benjamin C Creelan, Chao Wang, Jamie K Teer, Eric M Toloza, Jiqiang Yao, Sungjune Kim, Ana M Landin, John E Mullinax, James J Saller, Andreas N Saltos, David R Noyes, Leighann B Montoya, Wesley Curry, Shari A Pilon-Thomas, Alberto A Chiappori, Tawee Tanvetyanon, Frederic J Kaye, Zachary J Thompson, Sean J Yoder, Bin Fang, John M Koomen, Amod A Sarnaik, Dung-Tsa Chen, José R Conejo-Garcia, Eric B Haura, Scott J Antonia
Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial. Nature medicine 27 (8) (2021)
Hitendra S Solanki, Eric A Welsh, Bin Fang, Victoria Izumi, Lancia Darville, Brandon Stone, Ryan Franzese, Sandip Chavan, Fumi Kinose, Denis Imbody, John M Koomen, Uwe Rix, Eric B Haura
Cell Type-specific Adaptive Signaling Responses to KRASG12C Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (9) (2021)
Gregory Watson, Daniel Lester, Hui Ren, Connor M Forsyth, Elliot Medina, David Gonzalez Perez, Lancia Darville, Jiqiang Yao, Vince Luca, John M Koomen, Ling Cen, Eric Lau
Fucosylated Proteome Profiling Identifies a Fucosylated, Non-Ribosomal, Stress-Responsive Species of Ribosomal Protein S3. Cells 10 (6) (2021)
David C Koomen, Mark B Meads, Dario M Magaletti, Joy D Guingab-Cagmat, Paula S Oliveira, Bin Fang, Min Liu, Eric A Welsh, Laurel E Meke, Zhijie Jiang, Oliver A Hampton, Alexandre Tungesvik, Gabriel De Avila, Raghunandan Reddy Alugubelli, Taiga Nishihori, Ariosto S Silva, Steven A Eschrich, Timothy J Garrett, John M Koomen, Kenneth H Shain
Metabolic Changes Are Associated with Melphalan Resistance in Multiple Myeloma. Journal of proteome research 20 (6) (2021)
Inna Smalley, Vincent Law, Clayton Wyatt, Brittany Evernden, Bin Fang, John M Koomen, Eric A Welsh, Robert J B Macaulay, Peter A Forsyth, Keiran S M Smalley
Proteomic Analysis of CSF from Patients with Leptomeningeal Melanoma Metastases Identifies Signatures Associated with Disease Progression and Therapeutic Resistance. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (9) (2020)
Bin Fang, Victoria Izumi, Lily L Remsing Rix, Eric Welsh, Ian Pike, Gary W Reuther, Eric B Haura, Uwe Rix, John M Koomen
Lowering Sample Requirements to Study Tyrosine Kinase Signaling Using Phosphoproteomics with the TMT Calibrator Approach. Proteomics 20 (24) (2020)
Andrew John Davis, Maksym Tsinkevich, Jason Rodencal, Hussein A Abbas, Xiao-Hua Su, Young-Jin Gi, Bin Fang, Kimal Rajapakshe, Cristian Coarfa, Preethi H Gunaratne, John M Koomen, Kenneth Y Tsai, Elsa R Flores
TAp63-Regulated miRNAs Suppress Cutaneous Squamous Cell Carcinoma through Inhibition of a Network of Cell-Cycle Genes. Cancer research 80 (12) (2020)
Fernanda Faião-Flores, Michael F Emmons, Michael A Durante, Fumi Kinose, Biswarup Saha, Bin Fang, John M Koomen, Srikumar P Chellappan, Silvya Stuchi Maria-Engler, Uwe Rix, Jonathan D Licht, J William Harbour, Keiran S M Smalley
HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)
Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jürgen Christian Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian A Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, Keiran S M Smalley
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy. Cancer research 79 (11) (2019)
Qing Yin, Tao Han, Bin Fang, Guolin Zhang, Chao Zhang, Evan R Roberts, Victoria Izumi, Mengmeng Zheng, Shulong Jiang, Xiu Yin, Minjung Kim, Jianfeng Cai, Eric B Haura, John M Koomen, Keiran S M Smalley, Lixin Wan
K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling. Nature communications 10 (1) (2019)
Maria C Ramello, Ismahène Benzaïd, Brent M Kuenzi, Maritza Lienlaf-Moreno, Wendy M Kandell, Daniel N Santiago, Mibel Pabón-Saldaña, Lancia Darville, Bin Fang, Uwe Rix, Sean Yoder, Anders E Berglund, John M Koomen, Eric B Haura, Daniel Abate-Daga
An immunoproteomic approach to characterize the CAR interactome and signalosome. Science signaling 12 (568) (2019)
Paul Allen Stewart, Eric A Welsh, Robbert J C Slebos, Bin Fang, Victoria Izumi, Matthew Chambers, Guolin Zhang, Ling Cen, Fredrik Pettersson, Yonghong Zhang, Zhihua Chen, Chia-Ho Cheng, Ram Thapa, Zachary Thompson, Katherine M Fellows, Jewel M Francis, James J Saller, Tania Mesa, Chaomei Zhang, Sean Yoder, Gina M DeNicola, Amer A Beg, Theresa A Boyle, Jamie K Teer, Yian Ann Chen, John M Koomen, Steven A Eschrich, Eric B Haura
Proteogenomic landscape of squamous cell lung cancer. Nature communications 10 (1) (2019)
Kristen S Hill, Evan R Roberts, Xue Wang, Ellen Marin, Taeeun D Park, Sorany Son, Yuan Ren, Bin Fang, Sean Yoder, Sungjune Kim, Lixin Wan, Amod A Sarnaik, John M Koomen, Jane L Messina, Jamie K Teer, Youngchul Kim, Jie Wu, Charles E Chalfant, Minjung Kim
PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas. Molecular cancer research : MCR 17 (2) (2018)
Dehuang Guo, Qinqin Xu, Sarabjot Pabla, John M Koomen, Paul Biddinger, Ashok Sharma, Simarjot Pabla, Rafal Pacholczyk, Chien-Chung Chang, Kevin Friedrich, Kamran Mohammed, Robert C Smallridge, John A Copland, Jin-Xiong She, Paul M Weinberger
Cytokeratin-8 in Anaplastic Thyroid Carcinoma: More Than a Simple Structural Cytoskeletal Protein. International journal of molecular sciences 19 (2) (2018)
Melissa A Hoffman, Bin Fang, Eric B Haura, Uwe Rix, John M Koomen
Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. Journal of proteome research 17 (1) (2017)

John M Koomen.css-eqlu8i{font-size:small;padding-left:4px;} (John Koomen)

Publication Activity (10 Years)

Top Topics

Top Venues

John M Koomen (John Koomen)