Isaac M Chiu

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 43

Top Venues

Nature

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

Nature communications

Harvard Medical School

Harvard medical school (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School Sep 02 2014

United States

Assistant Professor :: Immunology

Boston Children's Hospital

United States

Postdoctoral fellow :: Kirby Neurobiology Center

Education History

Harvard medical school

United States

PHD :: Immunology

Publications

Yangyang Zhu, Kimberly A Meerschaert, Silvia Galvan-Pena, Na-Ryum Bin, Daping Yang, Himanish Basu, Ryo Kawamoto, Amre Shalaby, Stephen D Liberles, Diane Mathis, Christophe Benoist, Isaac M Chiu
A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut. Science (New York, N.Y.) 385 (6708) (2024)
Yangyang Zhu, Kimberly A Meerschaert, Silvia Galvan-Pena, Na-Ryum Bin, Daping Yang, Himanish Basu, Ryo Kawamoto, Amre Shalaby, Stephen D Liberles, Diane Mathis, Christophe Benoist, Isaac M Chiu
A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut. Science (New York, N.Y.) 385 (6708) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature (2024)
Warakorn Kulalert, Alexandria C Wells, Verena M Link, Ai Ing Lim, Nicolas Bouladoux, Motoyoshi Nagai, Oliver J Harrison, Olena Kamenyeva, Juraj Kabat, Michel Enamorado, Isaac M Chiu, Yasmine Belkaid
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota. Proceedings of the National Academy of Sciences of the United States of America 121 (11) (2024)
Yangyang Zhu, Kimberly A Meerschaert, Silvia Galvan-Pena, Na-Ryum Bin, Daping Yang, Himanish Basu, Ryo Kawamoto, Amre Shalaby, Stephen D Liberles, Diane Mathis, Christophe Benoist, Isaac M Chiu
A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut. Science (New York, N.Y.) 385 (6708) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Warakorn Kulalert, Alexandria C Wells, Verena M Link, Ai Ing Lim, Nicolas Bouladoux, Motoyoshi Nagai, Oliver J Harrison, Olena Kamenyeva, Juraj Kabat, Michel Enamorado, Isaac M Chiu, Yasmine Belkaid
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota. Proceedings of the National Academy of Sciences of the United States of America 121 (11) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Warakorn Kulalert, Alexandria C Wells, Verena M Link, Ai Ing Lim, Nicolas Bouladoux, Motoyoshi Nagai, Oliver J Harrison, Olena Kamenyeva, Juraj Kabat, Michel Enamorado, Isaac M Chiu, Yasmine Belkaid
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota. Proceedings of the National Academy of Sciences of the United States of America 121 (11) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Warakorn Kulalert, Alexandria C Wells, Verena M Link, Ai Ing Lim, Nicolas Bouladoux, Motoyoshi Nagai, Oliver J Harrison, Olena Kamenyeva, Juraj Kabat, Michel Enamorado, Isaac M Chiu, Yasmine Belkaid
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota. Proceedings of the National Academy of Sciences of the United States of America 121 (11) (2024)
Warakorn Kulalert, Alexandria C Wells, Verena M Link, Ai Ing Lim, Nicolas Bouladoux, Motoyoshi Nagai, Oliver J Harrison, Olena Kamenyeva, Juraj Kabat, Michel Enamorado, Isaac M Chiu, Yasmine Belkaid
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota. Proceedings of the National Academy of Sciences of the United States of America 121 (11) (2024)
Wanyu Li, Jessica A Plante, ChieYu Lin, Himanish Basu, Jesse S Plung, Xiaoyi Fan, Joshua M Boeckers, Jessica Oros, Tierra K Buck, Praju V Anekal, Wesley A Hanson, Haley Varnum, Adrienne Wells, Colin J Mann, Laurentia V Tjang, Pan Yang, Rachel A Reyna, Brooke M Mitchell, Divya P Shinde, Jordyn L Walker, So Yoen Choi, Vesna Brusic, Paula Montero Llopis, Scott C Weaver, Hisashi Umemori, Isaac M Chiu, Kenneth S Plante, Jonathan Abraham
Shifts in receptors during submergence of an encephalitic arbovirus. Nature 632 (8025) (2024)
Na-Ryum Bin, Sara L Prescott, Nao Horio, Yandan Wang, Isaac M Chiu, Stephen D Liberles
An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature 615 (7952) (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature 615 (7952) (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature 615 (7952) (2023)
Na-Ryum Bin, Sara L Prescott, Nao Horio, Yandan Wang, Isaac M Chiu, Stephen D Liberles
An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature 615 (7953) (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature (2023)
Na-Ryum Bin, Sara L Prescott, Nao Horio, Yandan Wang, Isaac M Chiu, Stephen D Liberles
An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature 615 (7953) (2023)
Na-Ryum Bin, Sara L Prescott, Nao Horio, Yandan Wang, Isaac M Chiu, Stephen D Liberles
An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature 615 (7953) (2023)
Na-Ryum Bin, Sara L Prescott, Nao Horio, Yandan Wang, Isaac M Chiu, Stephen D Liberles
An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature (2023)
Daping Yang, Nicole Almanzar, Isaac M Chiu
The role of cellular and molecular neuroimmune crosstalk in gut immunity. Cellular & molecular immunology (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature (2023)
Felipe A Pinho-Ribeiro, Liwen Deng, Dylan V Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S Doran, Dan Levy, Isaac M Chiu
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature 615 (7952) (2023)
Larissa Staurengo-Ferrari, Liwen Deng, Isaac M Chiu
Interactions between nociceptor sensory neurons and microbial pathogens in pain. Pain 163 (Suppl 1) (2022)
Swalpa Udit, Kimbria Blake, Isaac M Chiu
Somatosensory and autonomic neuronal regulation of the immune response. Nature reviews. Neuroscience 23 (3) (2022)
Dylan V Neel, Himanish Basu, Georgia Gunner, Isaac M Chiu
Catching a killer: Mechanisms of programmed cell death and immune activation in Amyotrophic Lateral Sclerosis. Immunological reviews 311 (1) (2022)
Amanda Jacobson, Daping Yang, Madeleine Vella, Isaac M Chiu
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes. Mucosal immunology 14 (3) (2021)
Tiphaine Voisin, Caroline Perner, Marie-Angele Messou, Stephanie I Shiers, Saltanat Ualiyeva, Yoshihide Kanaoka, Theodore John Price, Caroline L Sokol, Lora G Bankova, K Frank Austen, Isaac M Chiu
The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. Proceedings of the National Academy of Sciences of the United States of America 118 (13) (2021)
Liwen Deng, Isaac M Chiu
Microbes and pain. PLoS pathogens 17 (4) (2021)
Liliana M Sanmarco, Michael A Wheeler, Cristina Gutiérrez-Vázquez, Carolina Manganeli Polonio, Mathias Linnerbauer, Felipe A Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V Batterman, Giulia Scalisi, Stephanie E J Zandee, Evelyn S Heck, Moneera Alsuwailm, Douglas L Rosene, Burkhard Becher, Isaac M Chiu, Alexandre Prat, Francisco J Quintana
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature 590 (7846) (2021)
Lars E Clark, Sarah A Clark, ChieYu Lin, Jianying Liu, Adrian Coscia, Katherine Nabel Smith, Pan Yang, Dylan V Neel, Hyo Lee, Vesna Brusic, Iryna Stryapunina, Kenneth S Plante, Asim A Ahmed, Flaminia Catteruccia, Tracy L Young-Pearse, Isaac M Chiu, Paula Montero Llopis, Scott C Weaver, Jonathan Abraham
VLDLR and ApoER2 are receptors for multiple alphaviruses. Nature 602 (7897) (2021)
Nicole J Yang, Joerg Isensee, Dylan V Neel, Andreza U Quadros, Han-Xiong Bear Zhang, Justas Lauzadis, Sai Man Liu, Stephanie Shiers, Andreea Belu, Shilpa Palan, Sandra Marlin, Jacquie Maignel, Angela Kennedy-Curran, Victoria S Tong, Mahtab Moayeri, Pascal Röderer, Anja Nitzsche, Mike Lu, Bradley L Pentelute, Oliver Brüstle, Vineeta Tripathi, Keith A Foster, Theodore John Price, R John Collier, Stephen H Leppla, Michelino Puopolo, Bruce P Bean, Thiago M Cunha, Tim Hucho, Isaac M Chiu
Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2 + DRG sensory neurons. Nature neuroscience 25 (2) (2021)
Pankaj Baral, Swalpa Udit, Isaac M Chiu
Pain and immunity: implications for host defence. Nature reviews. Immunology 19 (7) (2020)
Felipe A Pinho-Ribeiro, Isaac M Chiu
Nociceptor nerves set the stage for skin immunity. Cell research 29 (11) (2020)
Meng Wu, Yaobing Chen, Han Xia, Changli Wang, Chin Yee Tan, Xunhui Cai, Yufeng Liu, Fenghu Ji, Peng Xiong, Ran Liu, Yuanlin Guan, Yaqi Duan, Dong Kuang, Sanpeng Xu, Hanghang Cai, Qin Xia, Dehua Yang, Ming-Wei Wang, Isaac M Chiu, Chao Cheng, Philip P Ahern, Liang Liu, Guoping Wang, Neeraj K Surana, Tian Xia, Dennis L Kasper
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases. Proceedings of the National Academy of Sciences of the United States of America 117 (45) (2020)
Kathy Wang, Omar K Yaghi, Raul German Spallanzani, Xin Chen, David Zemmour, Nicole Lai, Isaac M Chiu, Christophe Benoist, Diane Mathis
Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America 117 (10) (2020)
Kimbria J Blake, Pankaj Baral, Tiphaine Voisin, Ashira Lubkin, Felipe Almeida Pinho-Ribeiro, Kelsey L Adams, David P Roberson, Yuxin C Ma, Michael Otto, Clifford J Woolf, Victor J Torres, Isaac M Chiu
Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314. Nature communications 9 (1) (2018)
Pankaj Baral, Benjamin D Umans, Lu Li, Antonia Wallrapp, Meghna Bist, Talia Kirschbaum, Yibing Wei, Yan Zhou, Vijay K Kuchroo, Patrick R Burkett, Bryan G Yipp, Stephen D Liberles, Isaac M Chiu
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Nature medicine 24 (4) (2018)

Isaac M Chiu.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Isaac M Chiu