Burkhard Becher (Burkard Becher, Becher Burkhard)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 105

Top Venues

Nature immunology

Nature communications

Nature

Science immunology

University of Zurich

McGill University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Zurich

Switzerland

Asst. Prof :: Neurology

Dartmouth-Hitchcock Medical Center

United States

PostDoc :: Microbiology & Immunology

Education History

McGill University

Canada

PHD

University of Cologne

Germany

MSC :: Genetics

Publications

Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Elena Morandi, Véronique Adoue, Isabelle Bernard, Ekaterina Friebel, Nicolas Nunez, Yann Aubert, Frederick Masson, Anne S Dejean, Burkhard Becher, Anne Astier, Ludovic Martinet, Abdelhadi Saoudi
Impact of the Multiple Sclerosis-Associated Genetic Variant CD226 Gly307Ser on Human CD8 T-Cell Functions. Neurology(R) neuroimmunology & neuroinflammation 11 (6) (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology 25 (3) (2024)
Alice Driessen, Susanne Unger, An-Phi Nguyen, Rhonda E Ries, Soheil Meshinchi, Stefanie Kreutmair, Chiara Alberti, Pavel Sumazin, Richard Aplenc, Michele S Redell, Burkhard Becher, María Rodríguez Martínez
Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder. Life science alliance 7 (11) (2024)
Kathleen A M Mills, Frederike Westermann, Vanessa Espinosa, Eric Rosiek, Jigar V Desai, Mariano A Aufiero, Yahui Guo, Kennedy A Mitchell, Selma Tuzlak, Donatella De Feo, Michail S Lionakis, Amariliz Rivera, Burkhard Becher, Tobias M Hohl
GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus . bioRxiv : the preprint server for biology (2024)
Janaki Manoja Vinnakota, Rachael C Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James R Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R Blazar, Justus Duyster, Melanie Börries, Natalie Stickel, Chintan M Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser
Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation. Science translational medicine 16 (751) (2024)
Kathleen A M Mills, Frederike Westermann, Vanessa Espinosa, Eric Rosiek, Jigar V Desai, Mariano A Aufiero, Yahui Guo, Kennedy A Mitchell, Selma Tuzlak, Donatella De Feo, Michail S Lionakis, Amariliz Rivera, Burkhard Becher, Tobias M Hohl
GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus . bioRxiv : the preprint server for biology (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology 25 (3) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Burkhard Becher, Tobias J Derfuss, Roland S Liblau
Targeting cytokine networks in neuroinflammatory diseases. Nature reviews. Drug discovery (2024)
Elena Morandi, Véronique Adoue, Isabelle Bernard, Ekaterina Friebel, Nicolas Nunez, Yann Aubert, Frederick Masson, Anne S Dejean, Burkhard Becher, Anne Astier, Ludovic Martinet, Abdelhadi Saoudi
Impact of the Multiple Sclerosis-Associated Genetic Variant CD226 Gly307Ser on Human CD8 T-Cell Functions. Neurology(R) neuroimmunology & neuroinflammation 11 (6) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology 25 (3) (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology (2024)
Alice Driessen, Susanne Unger, An-Phi Nguyen, Rhonda E Ries, Soheil Meshinchi, Stefanie Kreutmair, Chiara Alberti, Pavel Sumazin, Richard Aplenc, Michele S Redell, Burkhard Becher, María Rodríguez Martínez
Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder. Life science alliance 7 (11) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology 25 (3) (2024)
Alice Driessen, Susanne Unger, An-Phi Nguyen, Rhonda E Ries, Soheil Meshinchi, Stefanie Kreutmair, Chiara Alberti, Pavel Sumazin, Richard Aplenc, Michele S Redell, Burkhard Becher, María Rodríguez Martínez
Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder. Life science alliance 7 (11) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Tobias Wertheimer, Pascale Zwicky, Lukas Rindlisbacher, Colin Sparano, Marijne Vermeer, Bruno Marcel Silva de Melo, Claudia Haftmann, Tamina Rückert, Aakriti Sethi, Stefanie Schärli, Anna Huber, Florian Ingelfinger, Caroline Xu, Daehong Kim, Philipp Häne, André Fonseca da Silva, Andreas Muschaweckh, Nicolás Gonzalo Nuñez, Sinduya Krishnarajah, Natalie Stickel, Robert Zeiser, Mohamed Oukka, Thomas Korn, Sonia Tugues, Burkhard Becher
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment. Nature immunology 25 (3) (2024)
Florentia Dimitriou, Phil Fang Cheng, Annalisa Saltari, Katrin Schaper-Gerhardt, Ramon Staeger, Veronika Haunerdinger, Federica Sella, Aizhan Tastanova, Christian Urban, Susanne Dettwiler, Daniela Mihic-Probst, Christian M Matter, Olivier Michielin, Ralf Gutzmer, Georgina V Long, Burkhard Becher, Mitchell Paul Levesque, Reinhard Dummer
A targetable type III immune response with increase of IL-17A expressing CD4 + T cells is associated with immunotherapy-induced toxicity in melanoma. Nature cancer (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Janaki Manoja Vinnakota, Rachael C Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James R Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R Blazar, Justus Duyster, Melanie Börries, Natalie Stickel, Chintan M Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser
Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation. Science translational medicine 16 (751) (2024)
Giorgia Serena Gullotta, Donatella De Feo, Ekaterina Friebel, Aurora Semerano, Giulia Maria Scotti, Andrea Bergamaschi, Erica Butti, Elena Brambilla, Angela Genchi, Alessia Capotondo, Mattia Gallizioli, Simona Coviello, Marco Piccoli, Tiziana Vigo, Patrizia Della Valle, Paola Ronchi, Giancarlo Comi, Armando D'Angelo, Norma Maugeri, Luisa Roveri, Antonio Uccelli, Burkhard Becher, Gianvito Martino, Marco Bagicaluppi
Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology. Nature immunology (2023)
Nicolás Gonzalo Nuñez, Jonas Schmid, Laura Power, Chiara Alberti, Sinduya Krishnarajah, Stefanie Kreutmair, Susanne Unger, Sebastián Blanco, Brenda Konigheim, Constanza Marín, Luisina Onofrio, Jenny Christine Kienzler, Sara Costa-Pereira, Florian Ingelfinger, null null, null null, Marina E Pasinovich, Juan M Castelli, Carla Vizzotti, Maximilian Schaefer, Juan Villar-Vesga, Sarah Mundt, Carla Helena Merten, Aakriti Sethi, Tobias Wertheimer, Mirjam Lutz, Danusia Vanoaica, Claudia Sotomayor, Adriana Gruppi, Christian Münz, Diego Cardozo, Gabriela Barbás, Laura Lopez, Paula Carreño, Gonzalo Castro, Elias Raboy, Sandra Gallego, Gabriel Morón, Laura Cervi, Eva Virginia Acosta Rodríguez, Belkys A Maletto, Mariana Maccioni, Burkhard Becher
High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity. Nature immunology (2023)
Myrto Andreadou, Florian Ingelfinger, Donatella De Feo, Teresa L M Cramer, Selma Tuzlak, Ekaterina Friebel, Bettina Schreiner, Pascale Eede, Shirin Schneeberger, Maria Geesdorf, Frederike Ridder, Christina A Welsh, Laura Power, Daniel Kirschenbaum, Shiva K Tyagarajan, Melanie Greter, Frank L Heppner, Sarah Mundt, Burkhard Becher
IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice. Nature neuroscience (2023)
Nicolás Gonzalo Nuñez, Jonas Schmid, Laura Power, Chiara Alberti, Sinduya Krishnarajah, Stefanie Kreutmair, Susanne Unger, Sebastián Blanco, Brenda Konigheim, Constanza Marín, Luisina Onofrio, Jenny Christine Kienzler, Sara Costa-Pereira, Florian Ingelfinger, null null, null null, Marina E Pasinovich, Juan M Castelli, Carla Vizzotti, Maximilian Schaefer, Juan Villar-Vesga, Sarah Mundt, Carla Helena Merten, Aakriti Sethi, Tobias Wertheimer, Mirjam Lutz, Danusia Vanoaica, Claudia Sotomayor, Adriana Gruppi, Christian Münz, Diego Cardozo, Gabriela Barbás, Laura Lopez, Paula Carreño, Gonzalo Castro, Elias Raboy, Sandra Gallego, Gabriel Morón, Laura Cervi, Eva Virginia Acosta Rodríguez, Belkys A Maletto, Mariana Maccioni, Burkhard Becher
High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity. Nature immunology (2023)
Jenny Christine Kienzler, Burkhard Becher
Immunity in malignant brain tumors - Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment. European journal of immunology (2023)
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M Woessner, Hans D Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R Blazar, Susana Minguet, Patrick Turko, Mitchell Paul Levesque, Burkhard Becher, Robert Zeiser
MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production. Molecular cancer research : MCR (2023)
Nicolás Gonzalo Nuñez, Jonas Schmid, Laura Power, Chiara Alberti, Sinduya Krishnarajah, Stefanie Kreutmair, Susanne Unger, Sebastián Blanco, Brenda Konigheim, Constanza Marín, Luisina Onofrio, Jenny Christine Kienzler, Sara Costa-Pereira, Florian Ingelfinger, null null, null null, Marina E Pasinovich, Juan M Castelli, Carla Vizzotti, Maximilian Schaefer, Juan Villar-Vesga, Sarah Mundt, Carla Helena Merten, Aakriti Sethi, Tobias Wertheimer, Mirjam Lutz, Danusia Vanoaica, Claudia Sotomayor, Adriana Gruppi, Christian Münz, Diego Cardozo, Gabriela Barbás, Laura Lopez, Paula Carreño, Gonzalo Castro, Elias Raboy, Sandra Gallego, Gabriel Morón, Laura Cervi, Eva Virginia Acosta Rodríguez, Belkys A Maletto, Mariana Maccioni, Burkhard Becher
High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity. Nature immunology (2023)
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O Wenzel, Oliver M Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T Lindenmeyer, Elion Hoxha, Rolf A K Stahl, Tobias B Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F Krebs, Ulf Panzer
CD4 + T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12. Science translational medicine 15 (687) (2023)
Florian Ingelfinger, Michael Kramer, Mirjam Lutz, Corinne C Widmer, Luca Piccoli, Stefanie Kreutmair, Tobias Wertheimer, Mark Woodhall, Patrick Waters, Federica Sallusto, Antonio Lanzavecchia, Sarah Mundt, Burkhard Becher, Bettina Schreiner
Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates. Neurology(R) neuroimmunology & neuroinflammation 10 (2) (2023)
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O Wenzel, Oliver M Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T Lindenmeyer, Elion Hoxha, Rolf A K Stahl, Tobias B Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F Krebs, Ulf Panzer
CD4 + T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12. Science translational medicine 15 (687) (2023)
John G McKendrick, Gareth-Rhys Jones, Sonia S Elder, Erin Watson, Wouter T'Jonck, Ella Mercer, Marlene Magalhaes Pinto, Cecilia Rocchi, Lizi M Hegarty, Amanda L Johnson, Christoph Schneider, Burkhard Becher, Clare Pridans, Neil A Mabbott, Zhaoyuan Liu, Florent Ginhoux, Marc Bajenoff, Rebecca Gentek, Calum C Bain, Elaine Emmerson
CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury. Science immunology 8 (89) (2023)
Florian Ingelfinger, Michael Kramer, Mirjam Lutz, Corinne C Widmer, Luca Piccoli, Stefanie Kreutmair, Tobias Wertheimer, Mark Woodhall, Patrick Waters, Federica Sallusto, Antonio Lanzavecchia, Sarah Mundt, Burkhard Becher, Bettina Schreiner
Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates. Neurology(R) neuroimmunology & neuroinflammation 10 (2) (2023)
Sonja Marinović, Maja Lenartić, Karlo Mladenić, Marko Šestan, Inga Kavazović, Ante Benić, Mia Krapić, Lukas Rindlisbacher, Maja Cokarić Brdov Ak, Colin Sparano, Gioana Litscher, Tamara Turk Wensveen, Ivana Mikolašević, Dora Fǔkar Čupić, Lidija Bilić-Zulle, Aleksander Steinle, Esther Von Stebut, Adrian C Hayday, Sonia Tugues, Burkhard Becher, Bojan Polic, Felix M Wensveen
NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis. Science immunology 8 (87) (2023)
Florian Ingelfinger, Michael Kramer, Mirjam Lutz, Corinne C Widmer, Luca Piccoli, Stefanie Kreutmair, Tobias Wertheimer, Mark Woodhall, Patrick Waters, Federica Sallusto, Antonio Lanzavecchia, Sarah Mundt, Burkhard Becher, Bettina Schreiner
Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates. Neurology(R) neuroimmunology & neuroinflammation 10 (2) (2023)
Dilay Cansever, Ekaterina Petrova, Sinduya Krishnarajah, Caroline Mussak, Christina A Welsh, Wiebke Mildenberger, Kevin Mulder, Victor Kreiner, Elsa Roussel, Sebastian Anton Stifter, Myrto Andreadou, Pascale Zwicky, Nicole Puertas Jurado, Hubert Rehrauer, Ge Tan, Zhaoyuan Liu, Camille Blériot, Francesca Ronchi, Andrew J Macpherson, Florent Ginhoux, Giancarlo Natalucci, Burkhard Becher, Melanie Greter
Lactation-associated macrophages exist in murine mammary tissue and human milk. Nature immunology (2023)
Aaron James Forde, Julia Kolter, Pascale Zwicky, Sebastian Baasch, Florens Lohrmann, Marleen Eckert, Vitka Gres, Simon Lagies, Oliver Gorka, Angelika S Rambold, Joerg M Buescher, Bernd Kammerer, Nico Lachmann, Marco Prinz, Olaf Gross, Edward J Pearce, Burkhard Becher, Philipp Henneke
Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection. Science immunology 8 (86) (2023)
Thomas Look, Emanuele Puca, Marcel Bühler, Daniel Kirschenbaum, Roberto De Luca, Riccardo Stucchi, Domenico Ravazza, Cesare Di Nitto, Patrick Roth, Yonatan Katzenelenbogen, Assaf Weiner, Lukas Rindlisbacher, Burkhard Becher, Bjørt K Kragesteen, Michael Weller, Dario Neri, Teresa Hemmerle, Tobias Weiss
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma. Science translational medicine 15 (697) (2023)
Colin Sparano, Darío Solís-Sayago, Anjali Vijaykumar, Chiara Rickenbach, Marijne Vermeer, Florian Ingelfinger, Gioana Litscher, André Fonseca da Silva, Caroline Mussak, Maud Mayoux, Christin Friedrich, Cesar Nombela-Arrieta, Georg Gasteiger, Burkhard Becher, Sonia Tugues
Embryonic and neonatal waves generate distinct populations of hepatic ILC1s. Science immunology 7 (75) (2022)
Florian Ingelfinger, Lisa Ann Gerdes, Vladyslav Kavaka, Sinduya Krishnarajah, Ekaterina Friebel, Edoardo Galli, Pascale Zwicky, Reinhard Furrer, Christian Peukert, Charles-Antoine Dutertre, Klara Magdalena Eglseer, Florent Ginhoux, Andrea Flierl-Hecht, Tania Kümpfel, Donatella De Feo, Bettina Schreiner, Sarah Mundt, Martin Kerschensteiner, Reinhard Hohlfeld, Eduardo Beltrán, Burkhard Becher
Twin study reveals non-heritable immune perturbations in multiple sclerosis. Nature 603 (7899) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature 615 (7950) (2022)
Selma Tuzlak, Florent Ginhoux, Thomas Korn, Burkhard Becher
Reply to 'Comment on: Repositioning T H cell polarization from single cytokines to complex help'. Nature immunology 23 (4) (2022)
Ana Amorim, Donatella De Feo, Ekaterina Friebel, Florian Ingelfinger, Cyrill Dimitri Anderfuhren, Sinduya Krishnarajah, Myrto Andreadou, Christina A Welsh, Zhaoyuan Liu, Florent Ginhoux, Melanie Greter, Burkhard Becher
IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation. Nature immunology 23 (2) (2022)
Sarah A Dick, Anthony Wong, Homaira Hamidzada, Sara Nejat, Robert Nechanitzky, Shabana Vohra, Brigitte Mueller, Rysa Zaman, Crystal Kantores, Laura Aronoff, Abdul Momen, Duygu Nechanitzky, Wanda Y Li, Parameswaran Ramachandran, Sarah Q Crome, Burkhard Becher, Myron I Cybulsky, Filio Billia, Shaf Keshavjee, Seema Mital, Clint S Robbins, Tak Wah Mak, Slava Epelman
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Science immunology 7 (67) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature 615 (7950) (2022)
Tommy Regen, Sandrine Isaac, Ana Amorim, Nicolás Gonzalo Núñez, Judith Hauptmann, Arthi Shanmugavadivu, Matthias Klein, Roman Sankowski, Ilgiz A Mufazalov, Nir Yogev, Jula Huppert, Florian Wanke, Michael Witting, Alexandra Grill, Eric J C Gálvez, Alexei Nikolaev, Michaela Blanfeld, Immo Prinz, Philippe Schmitt-Kopplin, Till Strowig, Christian Reinhardt, Marco Prinz, Tobias Bopp, Burkhard Becher, Carles Ubeda, Esther Von Stebut
IL-17 controls central nervous system autoimmunity through the intestinal microbiome. Science immunology 6 (56) (2022)
Martin Diebold, Edoardo Galli, Andreas Kopf, Nicholas S R Sanderson, Ilaria Callegari, Pascal Benkert, Nicolás Gonzalo Núñez, Florian Ingelfinger, Stefan Herms, Sven Cichon, Ludwig Kappos, Jens Kuhle, Burkhard Becher, Manfred Claassen, Tobias Derfuss
High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America 119 (31) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature 615 (7950) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature 615 (7950) (2022)
Ilena Vincenti, Nicolas Page, Karin Steinbach, Alexander Yermanos, Sylvain Lemeille, Nicolas Nunez, Mario Kreutzfeldt, Bogna Klimek, Giovanni Di Liberto, Kristof Egervari, Margot Piccinno, Ghazal Shammas, Alexandre Mariotte, Nicolas Fonta, Nicolas Liaudet, Danielle Shlesinger, Anna Rita Liuzzi, Ingrid Wagner, Cynthia Saadi, Christine Stadelmann, Sai T Reddy, Burkhard Becher, Doron Merkler
Tissue-resident memory CD8 + T cells cooperate with CD4 + T cells to drive compartmentalized immunopathology in the CNS. Science translational medicine 14 (640) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature 615 (7950) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defence and immune responses in colitis. Nature (2022)
Jenny N H G Ho, Dominik Schmidt, Theresa Lowinus, Jeongmin Ryoo, Elaine-Pashupati Dopfer, Nicolás Gonzalo Núñez, Sara Costa-Pereira, Cristina Toffalori, Marco Punta, Viktor Fetsch, Tobias Wertheimer, Marie-Claire Rittmann, Lukas M Braun, Marie Follo, Christelle Briere, Janaki Manoja Vinnakota, Marlene Langenbach, Felicitas Koppers, Khalid Shoumariyeh, Helena Engel, Tamina Rückert, Melanie Märklin, Samuel Holzmayer, Anna L Illert, Federica Magon, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Julian Staniek, Marta Rizzi, Christoph Cornelius Miething, Natalie Stickel, Justus Duyster, Hans D Menssen, Melanie Börries, Joerg M Buescher, Nina Cabezas-Wallscheid, Bruce R Blazar, Petya Apostolova, Luca Vago, Erika L Pearce, Burkhard Becher, Robert Zeiser
Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140 (10) (2022)
Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás Gonzalo Nuñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma M C Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle Catherine Arnold
Active eosinophils regulate host defense and immune responses in colitis. Nature (2022)
Giuseppe Locatelli, Filipa Marques-Ferreira, Antonis Katsoulas, Vasileia Kalaitzaki, Martin Krueger, Barbara Ingold-Heppner, Sabrina Walthert, Roman Sankowski, Olivia Prazeres da Costa, Amalia Dolga, Magdalena Huber, Maike Gold, Carsten Culmsee, Esther Von Stebut, Ingo Bechmann, Vladislava Milchevskaya, Marco Prinz, Achim Tresch, Burkhard Becher, Thorsten Buch
IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia (2022)
Sinduya Krishnarajah, Florian Ingelfinger, Ekaterina Friebel, Dilay Cansever, Ana Amorim, Myrto Andreadou, David Bamert, Gioana Litscher, Mirjam Lutz, Maud Mayoux, Sarah Mundt, Frederike Ridder, Colin Sparano, Sebastian Anton Stifter, Can Ulutekin, Susanne Unger, Marijne Vermeer, Pascale Zwicky, Melanie Greter, Sonia Tugues, Donatella De Feo, Burkhard Becher
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice. Nature aging 2 (1) (2021)
Laura Ducimetière, Giulia Lucchiari, Gioana Litscher, Marc Nater, Laura Heeb, Nicolás Gonzalo Nuñez, Laura Wyss, Dominik Burri, Marijne Vermeer, Julia Gschwend, Andreas E Moor, Burkhard Becher, Maries van den Broek, Sonia Tugues
Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis. Proceedings of the National Academy of Sciences of the United States of America 118 (27) (2021)
Giulia Agliardi, Anna Rita Liuzzi, Alastair Hotblack, Donatella De Feo, Nicolás Gonzalo Nuñez, Cassandra L Stowe, Ekaterina Friebel, Francesco Nannini, Lukas Rindlisbacher, Thomas A Roberts, Rajiv Ramasawmy, Iwan P Williams, Bernard M Siow, Mark F Lythgoe, Tammy L Kalber, Sergio A Quezada, Martin A Pule, Sonia Tugues, Karin Straathof, Burkhard Becher
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nature communications 12 (1) (2021)
Julia Gschwend, Samantha P M Sherman, Frederike Ridder, Xiaogang Feng, Hong-Erh Liang, Richard M Locksley, Burkhard Becher, Christoph Schneider
Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. The Journal of experimental medicine 218 (10) (2021)
Iva Lelios, Sebastian A Stifter, Virginia Cecconi, Ekaterina Petrova, Mirjam Lutz, Dilay Cansever, Sebastian G Utz, Burkhard Becher, Maries van den Broek, Melanie Greter
Monocytes promote UV-induced epidermal carcinogenesis. European journal of immunology 51 (7) (2021)
Diana Stoycheva, Ioana Sandu, Fabienne Gräbnitz, Ana Amorim, Mariana Borsa, Stefan Weber, Burkhard Becher, Annette Oxenius
Non-neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice. European journal of immunology 51 (6) (2021)
Sinduya Krishnarajah, Florian Ingelfinger, Ekaterina Friebel, Dilay Cansever, Ana Amorim, Myrto Andreadou, David Bamert, Gioana Litscher, Mirjam Lutz, Maud Mayoux, Sarah Mundt, Frederike Ridder, Colin Sparano, Sebastian Anton Stifter, Can Ulutekin, Susanne Unger, Marijne Vermeer, Pascale Zwicky, Melanie Greter, Sonia Tugues, Donatella De Feo, Burkhard Becher
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice. Nature aging 2 (1) (2021)
Claudia Haftmann, Pascale Zwicky, Florian Ingelfinger, Florian Mair, Stefan Floess, René Riedel, Pawel Durek, Marianne Rebecca Spalinger, Ekaterina Friebel, Brian P Leung, Mirjam Lutz, Nicole Puertas, Ana Amorim, Stefanie Schärli, Benedict Becher, Jan Kisielow, Esther Von Stebut, Mir-Farzin Mashreghi, Jochen Huehn, Burkhard Becher
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development. Science immunology 6 (65) (2021)
Orsolya Török, Bettina Schreiner, Johanna Schaffenrath, Hsing-Chuan Tsai, Upasana Maheshwari, Sebastian A Stifter, Christina A Welsh, Ana Amorim, Sucheta Sridhar, Sebastian G Utz, Wiebke Mildenberger, Sina Nassiri, Mauro Delorenzi, Adriano Aguzzi, May H Han, Melanie Greter, Burkhard Becher, Annika Keller
Pericytes regulate vascular immune homeostasis in the CNS. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Selma Tuzlak, Anne S Dejean, Matteo Iannacone, Francisco J Quintana, Esther Von Stebut, Florent Ginhoux, Thomas Korn, Burkhard Becher
Repositioning TH cell polarization from single cytokines to complex help. Nature immunology 22 (10) (2021)
Liliana M Sanmarco, Michael A Wheeler, Cristina Gutiérrez-Vázquez, Carolina Manganeli Polonio, Mathias Linnerbauer, Felipe A Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V Batterman, Giulia Scalisi, Stephanie E J Zandee, Evelyn S Heck, Moneera Alsuwailm, Douglas L Rosene, Burkhard Becher, Isaac M Chiu, Alexandre Prat, Francisco J Quintana
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature 590 (7846) (2021)
Sinduya Krishnarajah, Florian Ingelfinger, Ekaterina Friebel, Dilay Cansever, Ana Amorim, Myrto Andreadou, David Bamert, Gioana Litscher, Mirjam Lutz, Maud Mayoux, Sarah Mundt, Frederike Ridder, Colin Sparano, Sebastian Anton Stifter, Can Ulutekin, Susanne Unger, Marijne Vermeer, Pascale Zwicky, Melanie Greter, Sonia Tugues, Donatella De Feo, Burkhard Becher
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice. Nature aging 2 (1) (2021)
Dominik Pfister, Nicolás Gonzalo Nuñez, Roser Pinyol, Olivier Govaere, Matthias Pinter, Marta Szydlowska, Revant Gupta, Mengjie Qiu, Aleksandra Deczkowska, Assaf Weiner, Florian Müller, Ankit Sinha, Ekaterina Friebel, Thomas Engleitner, Daniela Lenggenhager, Anja Moncsek, Danijela Heide, Kristin Stirm, Jan Kosla, Eleni Kotsiliti, Valentina Leone, Michael Dudek, Suhail Yousuf, Donato Inverso, Indrabahadur Singh, Ana Teijeiro, Florian Castet, Carla Montironi, Philipp K Haber, Dina Tiniakos, Pierre Bedossa, Simon Cockell, Ramy Younes, Michele Vacca, Fabio Marra, Jörn M Schattenberg, Michael E D Allison, Elisabetta Bugianesi, Vlad Ratziu, Tiziana Pressiani, Antonio D'Alessio, Nicola Personeni, Lorenza Rimassa, Ann K Daly, Bernhard Scheiner, Katharina Pomej, Martha M Kirstein, Arndt Vogel, Markus Peck-Radosavljevic, Florian Hucke, Fabian Finkelmeier, Oliver Waidmann, Jörg Trojan, Kornelius Schulze, Henning Wege, Sandra Koch, Arndt Weinmann, Marco Bueter, Fabian Rössler, Alexander Siebenhüner, Sara De Dosso, Jan Philipp Mallm, Viktor Umansky, Manfred Jugold, Tom Luedde, Andrea Schietinger, Peter Schirmacher, Brinda Emu, Hellmut G Augustin, Adrian Billeter, Beat Müller-Stich, Hiroto Kikuchi, Dan G Duda, Fabian Kütting, Dirk-Thomas Waldschmidt, Matthias Philip Ebert, Nuh Rahbari, Henrik E Mei, Axel Ronald Schulz, Jane A McKeating, Nisar Malek, Stephan Spahn, Michael Bitzer, Marina Ruiz de Galarreta, Amaia Lujambio, Jean-François Dufour, Thomas U Marron, Ahmed Kaseb, Masatoshi Kudo, Yi-Hsiang Huang, Nabil Djouder, Katharina Wolter, Lars Zender, Parice N Marche, Thomas Decaens, David James Pinato, Roland Rad, Joachim C Mertens, Achim Weber, Kristian Unger, Rüdiger Klein, Susanne Roth, Zuzana Macek Jilkova, Manfred Claassen, Quentin M Anstee, Bjørt K Kragesteen, Percy A Knolle, Burkhard Becher, Josep M Llovet, Mathias F Heikenwälder
NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature 592 (7854) (2021)
Ming Wang, Yalong Yang, Dilay Cansever, Yiming Wang, Crystal Kantores, Sébastien Messiaen, Delphine Moison, Gabriel Livera, Svetoslav Chakarov, Tobias Weinberger, Christopher Stremmel, Monika Fijak, Britta Klein, Christiane Pleuger, Zhexiong Lian, Wentao Ma, Qingzhi Liu, Kathrin Klee, Kristian Händler, Thomas Ulas, Andreas Schlitzer, Joachim L Schultze, Burkhard Becher, Melanie Greter, Zhaoyuan Liu, Florent Ginhoux, Slava Epelman, Christian Schulz, Andreas Meinhardt, Sudhanshu Bhushan
Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis. Proceedings of the National Academy of Sciences of the United States of America 118 (1) (2021)
Alexandre Gallerand, Marion I Stunault, Johanna Merlin, Hannah P Luehmann, Deborah H Sultan, Maria M Firulyova, Virginie Magnone, Narges Khedher, Antoine Jalil, Bastien Dolfi, Alexia Castiglione, Adelie Dumont, Marion Ayrault, Nathalie Vaillant, Jérôme Gilleron, Pascal Barbry, David Dombrowicz, Matthias Mack, David Masson, Thomas Bertero, Burkhard Becher, Jesse W Williams, Konstantin Zaitsev, Yongjian Liu, Rodolphe R Guinamard, Laurent Yvan-Charvet, Stoyan Ivanov
Brown adipose tissue monocytes support tissue expansion. Nature communications 12 (1) (2021)
Sinduya Krishnarajah, Florian Ingelfinger, Ekaterina Friebel, Dilay Cansever, Ana Amorim, Myrto Andreadou, David Bamert, Gioana Litscher, Mirjam Lutz, Maud Mayoux, Sarah Mundt, Frederike Ridder, Colin Sparano, Sebastian Anton Stifter, Can Ulutekin, Susanne Unger, Marijne Vermeer, Pascale Zwicky, Melanie Greter, Sonia Tugues, Donatella De Feo, Burkhard Becher
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice. Nature aging 2 (1) (2021)
Paulino Tallón de Lara, Héctor Castañón, Marijne Vermeer, Nicolás Gonzalo Nuñez, Karina Silina, Bettina Sobottka, Joaquín Urdinez, Virginia Cecconi, Hideo Yagita, Farkhondeh Movahedian Attar, Stefanie Hiltbrunner, Isabelle Glarner, Holger Moch, Sònia Tugues, Burkhard Becher, Maries van den Broek
CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer. Nature communications 12 (1) (2021)
Florian Ingelfinger, Sinduya Krishnarajah, Michael Kramer, Sebastian G Utz, Edoardo Galli, Mirjam Lutz, Pascale Zwicky, Ayse U Akarca, Nicole Puertas Jurado, Can Ulutekin, David Bamert, Corinne C Widmer, Luca Piccoli, Federica Sallusto, Nicolás G Núñez, Teresa Marafioti, Didier Schneiter, Isabelle Opitz, Antonio Lanzavecchia, Hans H Jung, Donatella De Feo, Sarah Mundt, Bettina Schreiner, Burkhard Becher
Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta neuropathologica 141 (6) (2021)
Pascale Zwicky, Florian Ingelfinger, Bruno Marcel Silva de Melo, Fiorella Ruchti, Stefanie Schärli, Nicole Puertas, Mirjam Lutz, Truong San Phan, Thomas M Kündig, Mitchell Paul Levesque, Julia-Tatjana Maul, Christoph Schlapbach, Salomé LeibundGut-Landmann, Sarah Mundt, Burkhard Becher
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation. Science immunology 6 (64) (2021)
Sarah Mundt, Dunja Mrjden, Sebastian Guido Utz, Melanie Greter, Bettina Schreiner, Burkhard Becher
Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation. Science immunology 4 (31) (2020)
Burkhard Becher, Donatella De Feo, Ana Amorim, Melanie Greter
Skipping adolescence to become super-inflammatory monocytes. Nature immunology 21 (5) (2020)
Frederick M Lang, Kevin M C Lee, John R Teijaro, Burkhard Becher, John A Hamilton
GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches. Nature reviews. Immunology 20 (8) (2020)
Shaima'a Hamarsheh, Lena Osswald, Benedikt S Saller, Susanne Unger, Donatella De Feo, Janaki Manoja Vinnakota, Martina Konantz, Franziska M Uhl, Heiko Becker, Michael Lübbert, Khalid Shoumariyeh, Christoph Schürch, Geoffroy Andrieux, Nils Venhoff, Annette Schmitt-Graeff, Sandra Duquesne, Dietmar Pfeifer, Matthew A Cooper, Claudia Lengerke, Melanie Boerries, Justus Duyster, Charlotte M Niemeyer, Miriam Erlacher, Bruce R Blazar, Burkhard Becher, Olaf Groß, Tilman Brummer, Robert Zeiser
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation. Nature communications 11 (1) (2020)
Katrin Aslan, Verena Turco, Jens Blobner, Jana K Sonner, Anna Rita Liuzzi, Nicolás Gonzalo Nuñez, Donatella De Feo, Philipp Kickingereder, Manuel Fischer, Ed Green, Ahmed Sadik, Mirco Friedrich, Khwab Sanghvi, Michael Kilian, Frederik Cichon, Lara Wolf, Kristine Jähne, Anna von Landenberg, Lukas Bunse, Felix Sahm, Daniel Schrimpf, Jochen Meyer, Allen Alexander, Gianluca Brugnara, Ralph Röth, Kira Pfleiderer, Beate Niesler, Andreas von Deimling, Christiane A Opitz, Michael O Breckwoldt, Sabine Heiland, Martin Bendszus, Wolfgang Wick, Burkhard Becher, Michael Platten
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nature communications 11 (1) (2020)
Nicolás Gonzalo Nuñez, Jimena Tosello, Rodrigo Nalio Ramos, Wilfrid Richer, Nicolas Cagnard, Cyrill Dimitri Anderfuhren, Leticia Laura Niborski, Jeremy Bigot, Didier Meseure, Philippe De La Rochere, Maud Milder, Sophie Viel, Delphine Loirat, Louis Pérol, Anne Vincent-Salomon, Xavier Sastre-Garau, Burkhard Becher, Christine Sedlik, Olivier Lantz, Sebastian Amigorena, Eliane Piaggio
Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients. Nature communications 11 (1) (2020)
Edoardo Galli, Felix J Hartmann, Bettina Schreiner, Florian Ingelfinger, Eirini Arvaniti, Martin Diebold, Dunja Mrjden, Franziska van der Meer, Carsten Krieg, Faiez Al Nimer, Nicholas Sanderson, Christine Stadelmann, Mohsen Khademi, Fredrik Piehl, Manfred Claassen, Tobias Derfuss, Tomas Olsson, Burkhard Becher
GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis. Nature medicine 25 (8) (2019)
Selim Nur, Florian Sparber, Christina Lemberg, Eva Guiducci, Tiziano A Schweizer, Pascale Zwicky, Burkhard Becher, Salomé LeibundGut-Landmann
IL-23 supports host defense against systemic Candida albicans infection by ensuring myeloid cell survival. PLoS pathogens 15 (12) (2019)
Lifei Hou, Deepak A Rao, Koichi Yuki, Jessica Cooley, Lauren A Henderson, A Helena Jonsson, Dion Kaiserman, Mark P Gorman, Peter A Nigrovic, Phillip I Bird, Burkhard Becher, Eileen Remold-O'Donnell
SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America 116 (41) (2019)
Jan Hülsdünker, Oliver S Thomas, Eileen Haring, Susanne Unger, Nicolás Gonzalo Núñez, Sonia Tugues, Zhan Gao, Sandra Duquesne, Colette Cywes-Bentley, Ozlem Oyardi, Susanne Kirschnek, Annette Schmitt-Graeff, Oliver Pabst, Christian Koenecke, Justus Duyster, Petya Apostolova, Martin J Blaser, Burkhard Becher, Gerald B Pier, Georg Häcker, Robert Zeiser
Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity. Proceedings of the National Academy of Sciences of the United States of America 116 (41) (2019)
Jolanda Brummelman, Claudia Haftmann, Nicolás Gonzalo Núñez, Giorgia Alvisi, Emilia M C Mazza, Burkhard Becher, Enrico Lugli
Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry. Nature protocols 14 (7) (2019)
Sonia Tugues, Ana Amorim, Sabine Spath, Guillaume Martin-Blondel, Bettina Schreiner, Donatella De Feo, Mirjam Lutz, Franco Guscetti, Petya Apostolova, Claudia Haftmann, Peter Hasselblatt, Nicolas G Núñez, Michael O Hottiger, Maries van den Broek, Markus Gabriel Manz, Robert Zeiser, Burkhard Becher
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells. Science translational medicine 10 (469) (2019)
Edoardo Galli, Ekaterina Friebel, Florian Ingelfinger, Susanne Unger, Nicolás Gonzalo Núñez, Burkhard Becher
The end of omics? High dimensional single cell analysis in precision medicine. European journal of immunology 49 (2) (2019)
Nimitha R Mathew, Francis Baumgartner, Lukas Braun, David O'Sullivan, Simone Thomas, Miguel Waterhouse, Tony A Müller, Kathrin Hanke, Sanaz Taromi, Petya Apostolova, Anna L Illert, Wolfgang Melchinger, Sandra Duquesne, Annette Schmitt-Graeff, Lena Osswald, Kai-Li Yan, Arnim Weber, Sonia Tugues, Sabine Spath, Dietmar Pfeifer, Marie Follo, Rainer Claus, Michael Lübbert, Christoph Rummelt, Hartmut Bertz, Ralph Wäsch, Johanna Haag, Andrea Schmidts, Michael Schultheiss, Dominik Bettinger, Robert Thimme, Evelyn Ullrich, Yakup Tanriver, Giang Lam Vuong, Renate Arnold, Philipp Hemmati, Dominik Wolf, Markus Ditschkowski, Cordula Jilg, Konrad Wilhelm, Christian Leiber, Sabine Gerull, Jörg Halter, Claudia Lengerke, Thomas Pabst, Thomas Schroeder, Guido Kobbe, Wolf Rösler, Soroush Doostkam, Stephan Meckel, Kathleen Stabla, Stephan K Metzelder, Sebastian Halbach, Tilman Brummer, Zehan Hu, Joern Dengjel, Björn Hackanson, Christoph Schmid, Udo Holtick, Christof Scheid, Alexandros Spirydonidis, Friedrich Stölzel, Rainer Ordemann, Lutz P Müller, Flore Sicre-de-Fontbrune, Gabriele Ihorst, Jürgen Kuball, Jan E Ehlert, Daniel Feger, Eva-Maria Wagner, Jean-Yves Cahn, Jacqueline Schnell, Florian Kuchenbauer, Donald Bunjes, Ronjon Chakraverty, Simon Richardson, Saar Gill, Nicolaus Kröger, Francis Ayuk, Luca Vago, Fabio Ciceri, Antonia M Müller, Takeshi Kondo, Takanori Teshima, Susan Klaeger, Bernhard Kuster, Dennis Dong Hwan Kim, Daniel Weisdorf, Walter van der Velden, Daniela Dörfel, Wolfgang Bethge, Inken Hilgendorf, Andreas Hochhaus, Geoffroy Andrieux, Melanie Börries, Hauke Busch, John Magenau, Pavan Reddy, Myriam Labopin, Joseph H Antin, Andrea S Henden, Geoffrey R Hill, Glen A Kennedy, Merav Bar, Anita Sarma, Donal McLornan, Ghulam Mufti, Betul Oran, Katayoun Rezvani, Omid Shah, Robert S Negrin, Arnon Nagler, Marco Prinz, Andreas Burchert, Andreas Neubauer, Dietrich Beelen, Andreas Mackensen, Nikolas von Bubnoff, Wolfgang Herr, Burkhard Becher, Gerard Socié, Michael A Caligiuri, Eliana Ruggiero, Chiara Bonini, Georg Häcker, Justus Duyster, Jürgen Finke, Erika Pearce, Bruce R Blazar, Robert Zeiser
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature medicine 24 (3) (2018)
Carsten Krieg, Malgorzata Nowicka, Silvia Guglietta, Sabrina Schindler, Felix J Hartmann, Lukas M Weber, Reinhard Dummer, Mark D Robinson, Mitchell Paul Levesque, Burkhard Becher
High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy. Nature medicine 24 (2) (2018)
Kathrin Nussbaum, Sara H Burkhard, Isabel Ohs, Florian Mair, Christoph S N Klose, Sebastian J Arnold, Andreas Diefenbach, Sonia Tugues, Burkhard Becher
Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. The Journal of experimental medicine 214 (8) (2017)
Giacomo Casella, Annamaria Finardi, Hélène Descamps, Federico Colombo, Chiara Maiorino, Francesca Ruffini, Marco Patrone, Massimo Degano, Gianvito Martino, Luca Muzio, Burkhard Becher, Roberto Furlan
IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression. Scientific reports 7 (1) (2017)
Atsushi Anzai, Jennifer L Choi, Shun He, Ashley M Fenn, Manfred Nairz, Sara Rattik, Cameron S McAlpine, John E Mindur, Christopher T Chan, Yoshiko Iwamoto, Benoit Tricot, Gregory R Wojtkiewicz, Ralph Weissleder, Peter Libby, Matthias Nahrendorf, James R Stone, Burkhard Becher, Filip K Swirski
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes. The Journal of experimental medicine 214 (11) (2017)
Lucy S K Walker, Steven Ziegler, Burkhard Becher
Contemplating autoimmunity in the Aegean islands. Nature immunology 17 (3) (2016)

Burkhard Becher.css-eqlu8i{font-size:small;padding-left:4px;} (Burkard Becher, Becher Burkhard)

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Burkhard Becher (Burkard Becher, Becher Burkhard)