Isabelle Plo

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Venues

INSERM UMR 1170

INSERM EPI-9910 (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

INSERM UMR 1170

France

Director of Research :: Hématopoïèse normale et pathologique

INSERM UMR 1170

France

Researcher (CR1 INSERM) :: Hématopoïèse normale et pathologique

INSERM UMR790

France

Post-doctoral position :: Hématopoïèse normale et pathologique

UMR CNRS/CEA 217

France

Post-doctoral position :: Laboratoire d’études des mécanismes de la recombinaison

INSERM EPI-9910

France

Ph.D :: Laboratoire de pharmacologie anti-tumorale

NCI/NIH

United States

Doctoral internship :: Laboratory of molecular pharmacology

Education History

INSERM EPI-9910

France

PHD :: Toulouse III

Publications

Marie-Charlotte Bourrienne, Véronique Le Cam Duchez, Dorothée Faille, Carine Farkh, Mialitiana Solo Nomenjanahary, Juliette Gay, Stéphane Loyau, Clément Journé, Sébastien Dupont, Véronique Ollivier, Jean-Luc J-L Villeval, Isabelle Plo, Valérie Edmond, Martine Jandrot Perrus, Sylvie Labrouche-Colomer, Bruno Cassinat, Emmanuelle Verger, Jean-Philippe Désilles, Benoît Ho Ho Tin Noé, Aude Triquenot Bagan, Michael Mazighi, Nadine Ajzenberg
Exacerbation of thromboinflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis. Blood advances 8 (12) (2024)
Marie-Charlotte Bourrienne, Véronique Le Cam Duchez, Dorothée Faille, Carine Farkh, Mialitiana Solo Nomenjanahary, Juliette Gay, Stéphane Loyau, Clément Journé, Sébastien Dupont, Véronique Ollivier, Jean-Luc J-L Villeval, Isabelle Plo, Valérie Edmond, Martine Jandrot Perrus, Sylvie Labrouche-Colomer, Bruno Cassinat, Emmanuelle Verger, Jean-Philippe Désilles, Benoît Ho Ho Tin Noé, Aude Triquenot Bagan, Michael Mazighi, Nadine Ajzenberg
Exacerbation of thromboinflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis. Blood advances 8 (12) (2024)
Marie-Charlotte Bourrienne, Véronique Le Cam Duchez, Dorothée Faille, Carine Farkh, Mialitiana Solo Nomenjanahary, Juliette Gay, Stéphane Loyau, Clément Journé, Sébastien Dupont, Véronique Ollivier, Jean-Luc J-L Villeval, Isabelle Plo, Valérie Edmond, Martine Jandrot Perrus, Sylvie Labrouche-Colomer, Bruno Cassinat, Emmanuelle Verger, Jean-Philippe Désilles, Benoît Ho Ho Tin Noé, Aude Triquenot Bagan, Michael Mazighi, Nadine Ajzenberg
Exacerbation of thromboinflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis. Blood advances 8 (12) (2024)
Marie-Charlotte Bourrienne, Véronique Le Cam Duchez, Dorothée Faille, Carine Farkh, Mialitiana Solo Nomenjanahary, Juliette Gay, Stéphane Loyau, Clément Journé, Sébastien Dupont, Véronique Ollivier, Jean-Luc J-L Villeval, Isabelle Plo, Valérie Edmond, Martine Jandrot Perrus, Sylvie Labrouche-Colomer, Bruno Cassinat, Emmanuelle Verger, Jean-Philippe Désilles, Benoît Ho Ho Tin Noé, Aude Triquenot Bagan, Michael Mazighi, Nadine Ajzenberg
Exacerbation of thrombo-inflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis. Blood advances (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia 38 (4) (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia (2024)
Edimara Reis, Rebecca A Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, Bianca L Ferreira, Lynn Leffet, Lu Lu, Elodie Rosa, Maxime Evrard, Gaurang Trivedi, Brittney Wass, April Horsey, Xin He, Maryanne B Covington, Alla Volgina, Florence Pasquier, Laurence Legros, Guillemette Fouquet, William Vainchenker, Yan-Ou Yang, Breann Barker, Jing Zhou, Shaun Stewart, Ian S Hitchcock, Dashyant Dhanak, Ricardo Macarron, Isabelle Plo, Horacio G Nastri, Patrick A Mayes
Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN. Blood (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia 38 (4) (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia 38 (4) (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia 38 (4) (2024)
Hélène Duparc, Delphine Muller, Laure Gilles, Agathe L Chédeville, Mira El Khoury, Rose Guignard, Najet Debili, Monika Wittner, Alexandre Kauskot, Florence Pasquier, Iléana Antony-Debré, Caroline Marty, William Vainchenker, Isabelle Plo, Hana Raslova
Deregulation of the p19/CDK4/CDK6 axis in Jak2 V617F megakaryocytes accelerates the development of myelofibrosis. Leukemia (2024)
Charly Courdy, Loïc Platteeuw, Charlotte Ducau, Isabelle De Araujo, Emeline Boet, Ambrine Sahal, Estelle Saland, Valérie Edmond, Suzanne Tavitian, Sarah Bertoli, Pierre Cougoul, Fanny Granat, Laura Poillet, Caroline Marty, Isabelle Plo, Jean-Emmanuel Sarry, Stéphane Manenti, Véronique De Mas, Carine Joffre
Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2 V617F myeloproliferative neoplasms. Blood cancer journal 13 (1) (2023)
Christophe Willekens, Lucie Laplane, Tracy Dagher, Camelia Benlabiod, Nicolas Papadopoulos, Catherine Lacout, Philippe Rameau, Cyril Catelain, Alexia Alfaro, Valérie Edmond, Nicolas Signolle, Valentine Marchand, Nathalie M Droin, Remco Hoogenboezem, Rebekka K Schneider, Alex Penson, Omar Abdel-Wahab, Stephane Giraudier, Florence Pasquier, Caroline Marty, Isabelle Plo, Jean-Luc J-L Villeval, Stefan N Constantinescu, Françoise Porteu, William Vainchenker, Eric Solary
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice. Leukemia (2023)
Graciela Rabadan Moraes, Florence Pasquier, Christophe Marzac, Erick Deconinck, Carlotta Caterina Damanti, Gwendoline Leroy, Mira El-Khoury, Wassim El Nemer, Jean-Jacques Kiladjian, Hana Raslova, Albert Najman, William Vainchenker, Caroline Marty, Christine Bellanné-Chantelot, Isabelle Plo
An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2 V617F myeloproliferative neoplasms. British journal of haematology 198 (1) (2022)
Christian Pecquet, Nicolas Papadopoulos, Thomas Balligand, Ilyas Chachoua, Amandine Tisserand, Gaëlle Vertenoeil, Audrey Nédélec, Didier Vertommen, Anita Roy, Caroline Marty, Harini Nivarthi, Jean-Philippe Defour, Mira El-Khoury, Eva Hug, Andrea Majoros, Erica Xu, Oleh Zagrijtschuk, Tudor Emanuel Fertig, Daciana S Marta, Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, Ilaria Carola Casetti, Elisa Rumi, Daniela Pietra, Chiara Cavalloni, Luca Arcaini, Mario Cazzola, Norio Komatsu, Yoshihiko Kihara, Yoshitaka Sunami, Yoko Edahiro, Marito Araki, Roman Lesyk, Veronika Buxhofer-Ausch, Sonja Heibl, Florence Pasquier, Isabelle Plo, William Vainchenker, Robert Kralovics, Stefan N Constantinescu
Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms. Blood (2022)
Gurvan Hermange, Alicia Rakotonirainy, Mahmoud Bentriou, Amandine Tisserand, Mira El-Khoury, Francois Girodon, Christophe Marzac, William Vainchenker, Isabelle Plo, Paul-Henry Cournede
Inferring the initiation and development of myeloproliferative neoplasms. Proceedings of the National Academy of Sciences of the United States of America 119 (37) (2022)
Matthieu Mosca, Gurvan Hermange, Amandine Tisserand, Robert John Noble, Christophe Marzac, Caroline Marty, Cécile Le Sueur, Hugo Campario, Gaëlle Vertenoeil, Mira El-Khoury, Cyril Catelain, Philippe Rameau, Cyril Gella, Julien Lenglet, Nicole Casadevall, Rémi Favier, Eric Solary, Bruno Cassinat, Jean-Jacques Kiladjian, Stefan N Constantinescu, Florence Pasquier, Michael E Hochberg, Hana Raslova, Jean-Luc J-L Villeval, Francois Girodon, William Vainchenker, Paul-Henry Cournede, Isabelle Plo
Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms. Blood 138 (22) (2022)
Shohei Murakami, Vilma Barroca, Leïla Perié, Anne Bravard, Jacqueline Bernardino-Sgherri, Amandine Tisserand, Caroline Devanand, Valérie Edmond, Aurélie Magniez, Sabrina Tenreira Bento, Claire Torres, Florence Pasquier, Isabelle Plo, William Vainchenker, Jean-Luc J-L Villeval, Paul-Henri Roméo, Daniel Lewandowski
In Vivo Monitoring of Polycythemia Vera Development Reveals Carbonic Anhydrase 1 as a Potent Therapeutic Target. Blood cancer discovery 3 (4) (2022)
Ralfs Buks, Tracy Dagher, Maria Giustina Rotordam, David Monedero Alonso, Sylvie Cochet, Emilie-Fleur Gautier, Philippe Chafey, Bruno Cassinat, Jean-Jacques Kiladjian, Nadine Becker, Isabelle Plo, Stéphane Egée, Wassim El Nemer
Altered Ca 2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis. Cells 11 (1) (2021)
Francesca Basso-Valentina, Gabriel Levy, Leila N Varghese, Myriam Oufadem, Benedicte Neven, Charlotte Boussard, Nathalie Balayn, Caroline Marty, William Vainchenker, Isabelle Plo, Paola Ballerini, Stefan N Constantinescu, Remi Favier, Hana Raslova
CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag. Blood 138 (6) (2021)
Jean Pegliasco, Pierre Hirsch, Christophe Marzac, Françoise Isnard, Jean-Côme Meniane, Caroline Deswarte, Philippe Pellet, Céline Lemaitre, Gwendoline Leroy, Graciela Rabadan Moraes, Hélène Guermouche, Barbara Schmaltz-Panneau, Florence Pasquier, Chrystelle Colas, Patrick R Benusiglio, Odile Bera, Jean-Henri Bourhis, Eolia Brissot, Olivier Caron, Samy Chraibi, Pascale Cony-Makhoul, Christine Delaunay-Darivon, Simona Lapusan, Flore Sicre de Fontbrune, Pascal Fuseau, Albert Najman, William Vainchenker, François Delhommeau, Jean-Baptiste Micol, Isabelle Plo, Christine Bellanné-Chantelot
Germline ATG2B/GSKIP-containing 14q32 duplication predisposes to early clonal hematopoiesis leading to myeloid neoplasms. Leukemia (2021)
Stefania Mazzi, Philippe Dessen, Mathieu Vieira, Virginie Dufour, Marie Cambot, Mira El Khoury, Iléana Antony-Debré, Brahim Arkoun, Francesca Basso-Valentina, Salwa BenAbdoulahab, Valerie Edmond, Philippe Rameau, Rachel Petermann, Monika Wittner, Bruno Cassinat, Isabelle Plo, Najet Debili, Hana Raslova, William Vainchenker
Dual role of EZH2 in megakaryocyte differentiation. Blood 138 (17) (2021)
Mira El-Khoury, Xénia Cabagnols, Matthieu Mosca, Gaëlle Vertenoeil, Christophe Marzac, Fabrizia Favale, Olivier Bluteau, Florence Lorre, Amandine Tisserand, Graciela Rabadan Moraes, Valérie Ugo, Jean-Christophe Ianotto, Jerôme Rey, Eric Solary, Lydia Roy, Philippe Rameau, Najet Debili, Florence Pasquier, Nicole Casadevall, Caroline Marty, Stefan N Constantinescu, Hana Raslova, William Vainchenker, Isabelle Plo
Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms. Oncogene 39 (31) (2020)
Alessandro Donada, Nathalie Balayn, Dominika Sliwa, Larissa Lordier, Valentina Ceglia, Francesco Baschieri, Cyril Goizet, Rémi Favier, Lucie Tosca, Gérard Tachdjian, Cecile V Denis, Isabelle Plo, William Vainchenker, Najet Debili, Jean-Philippe Rosa, Marijke Bryckaert, Hana Raslova
Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity. Blood 133 (16) (2019)
Hugo Campario, Matthieu Mosca, Bernard Aral, Valentin Bourgeois, Pauline Martin, Antoine Brustel, Mathilde Filser, Christophe Marzac, Isabelle Plo, François Girodon
Impact of interferon on a triple positive polycythemia vera. Leukemia 34 (4) (2019)
Christine Bellanné-Chantelot, Barbara Schmaltz-Panneau, Caroline Marty, Odile Fenneteau, Isabelle Callebaut, Séverine Clauin, Aurélie Docet, Gandhi-Laurent Damaj, Thierry Leblanc, Isabelle Pellier, Cécile Stoven, Sylvie Souquere, Iléana Antony-Debré, Blandine Beaupain, Nathalie Aladjidi, Vincent Barlogis, Frédéric Bauduer, Philippe Bensaid, Odile Boespflug-Tanguy, Claire Berger, Yves Bertrand, Liana Carausu, Claire Fieschi, Claire Galambrun, Aline Schmidt, Hubert Journel, Françoise Mazingue, Brigitte Nelken, Thuan Chong Quah, Eric Oksenhendler, Marie Ouachée, Marlène Pasquet, Véronique Saada, Felipe Suarez, Gérard Pierron, William Vainchenker, Isabelle Plo, Jean Donadieu
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome. Blood 132 (12) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Isabelle Plo